Compare two consensus partitioning results
2024-02-27
Top 1000 genes under the two top-value methods
Figure 1. Top 1000 genes with the highest ATC and SD values.
Compare classifications
Figure 2. Conseusus partitions from ATC:skmeans and SD:kmeans methods.
Dimension reduction by UMAP
UMAP plots with 2-group classification for ATC:skmeans and 2-group classification for SD:kmeans:
Figure 3. UMAP plots for visualizing the two classifications. Classification on the left plot is from ATC:skmeans and on the right is from SD:kmeans.
Signature genes (FDR < 0.05)
Signature genes from two classifications:
ATC:skmeans (2 groups)
Figure 4A. Signature genes from ATC:skmeans (2-group classification).
SD:kmeans (2 groups)
Figure 4B. Signature genes from SD:kmeans (2-group classification).
Overlap of the two signature lists:
Figure 5. Overlap of signatures in ATC:skmeans and SD:kmeans.
The signature genes are put into three groups, termed as:
- A: 1178 genes specific in ATC:skmeans.
- B: 618 genes common in ATC:skmeans and SD:kmeans.
- C: 371 genes specific in SD:kmeans.
Figure 6. Heatmaps of ATC:skmeans specific signatures, SD:kmeans specific signatures and common signatures in the two classifcations.
Gene Ontology enrichment
Gene Ontology enrichment to the three set of genes are performed by hypergenometric test (with the clusterProfiler package). BP ontologies (Biological Process) is only applied and the significant GO terms are filtered by FDR < 0.01. The enriched GO terms are visualized as a heatmap by their similarities between GO terms (with GOSemSim package). GO terms are split and clustered with the simplifyEnrichment package. The keywords of the summaries of GO functions in each cluster are visualized by word clouds.
The most left heatmap illustrates the FDR of GO terms for each gene list. Red basically means significant.
Figure 7. Gene ontology enrichment (FDR < 0.001) on the three sets of genes illustrated in the previous Figure.
A1 (435 terms)
| ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
|---|---|---|---|---|---|---|
| GO:0033993 | response to lipid | 84/595 | 921/18614 | 0e+00 | 0e+00 | 84 |
| GO:0046903 | secretion | 84/595 | 960/18614 | 0e+00 | 0e+00 | 84 |
| GO:0003013 | circulatory system process | 63/595 | 602/18614 | 0e+00 | 0e+00 | 63 |
| GO:0009611 | response to wounding | 61/595 | 575/18614 | 0e+00 | 0e+00 | 61 |
| GO:0044057 | regulation of system process | 62/595 | 595/18614 | 0e+00 | 0e+00 | 62 |
| GO:0014070 | response to organic cyclic compound | 80/595 | 932/18614 | 0e+00 | 0e+00 | 80 |
| GO:0051050 | positive regulation of transport | 78/595 | 913/18614 | 0e+00 | 0e+00 | 78 |
| GO:0009725 | response to hormone | 75/595 | 880/18614 | 0e+00 | 0e+00 | 75 |
| GO:0008015 | blood circulation | 54/595 | 516/18614 | 0e+00 | 0e+00 | 54 |
| GO:0051046 | regulation of secretion | 60/595 | 632/18614 | 0e+00 | 0e+00 | 60 |
| GO:0099536 | synaptic signaling | 67/595 | 779/18614 | 0e+00 | 0e+00 | 67 |
| GO:0007268 | chemical synaptic transmission | 65/595 | 748/18614 | 0e+00 | 0e+00 | 65 |
| GO:0098916 | anterograde trans-synaptic signaling | 65/595 | 748/18614 | 0e+00 | 0e+00 | 65 |
| GO:0032940 | secretion by cell | 69/595 | 826/18614 | 0e+00 | 0e+00 | 69 |
| GO:0099537 | trans-synaptic signaling | 65/595 | 755/18614 | 0e+00 | 0e+00 | 65 |
| GO:0071417 | cellular response to organonitrogen compound | 60/595 | 669/18614 | 0e+00 | 0e+00 | 60 |
| GO:0140352 | export from cell | 72/595 | 902/18614 | 0e+00 | 0e+00 | 72 |
| GO:0046879 | hormone secretion | 38/595 | 305/18614 | 0e+00 | 0e+00 | 38 |
| GO:0008284 | positive regulation of cell population proliferation | 76/595 | 986/18614 | 0e+00 | 0e+00 | 76 |
| GO:0023061 | signal release | 49/595 | 483/18614 | 0e+00 | 0e+00 | 49 |
| GO:0030855 | epithelial cell differentiation | 62/595 | 725/18614 | 0e+00 | 0e+00 | 62 |
| GO:1901699 | cellular response to nitrogen compound | 61/595 | 707/18614 | 0e+00 | 0e+00 | 61 |
| GO:0009914 | hormone transport | 38/595 | 315/18614 | 0e+00 | 0e+00 | 38 |
| GO:0006936 | muscle contraction | 40/595 | 349/18614 | 0e+00 | 0e+00 | 40 |
| GO:0042886 | amide transport | 40/595 | 349/18614 | 0e+00 | 0e+00 | 40 |
| GO:0010817 | regulation of hormone levels | 51/595 | 533/18614 | 0e+00 | 0e+00 | 51 |
| GO:0035239 | tube morphogenesis | 72/595 | 942/18614 | 0e+00 | 0e+00 | 72 |
| GO:0001944 | vasculature development | 65/595 | 815/18614 | 0e+00 | 0e+00 | 65 |
| GO:0002790 | peptide secretion | 32/595 | 243/18614 | 0e+00 | 0e+00 | 32 |
| GO:0001568 | blood vessel development | 63/595 | 782/18614 | 0e+00 | 0e+00 | 63 |
| GO:0003012 | muscle system process | 45/595 | 452/18614 | 0e+00 | 0e+00 | 45 |
| GO:0046883 | regulation of hormone secretion | 32/595 | 247/18614 | 0e+00 | 0e+00 | 32 |
| GO:0043066 | negative regulation of apoptotic process | 69/595 | 913/18614 | 0e+00 | 0e+00 | 69 |
| GO:0043410 | positive regulation of MAPK cascade | 47/595 | 495/18614 | 0e+00 | 0e+00 | 47 |
| GO:0002791 | regulation of peptide secretion | 28/595 | 195/18614 | 0e+00 | 0e+00 | 28 |
| GO:1901652 | response to peptide | 48/595 | 514/18614 | 0e+00 | 0e+00 | 48 |
| GO:0050878 | regulation of body fluid levels | 39/595 | 361/18614 | 0e+00 | 0e+00 | 39 |
| GO:0030072 | peptide hormone secretion | 31/595 | 238/18614 | 0e+00 | 0e+00 | 31 |
| GO:0048514 | blood vessel morphogenesis | 58/595 | 701/18614 | 0e+00 | 0e+00 | 58 |
| GO:0090087 | regulation of peptide transport | 28/595 | 197/18614 | 0e+00 | 0e+00 | 28 |
| GO:0010562 | positive regulation of phosphorus metabolic process | 66/595 | 864/18614 | 0e+00 | 0e+00 | 66 |
| GO:0045937 | positive regulation of phosphate metabolic process | 66/595 | 864/18614 | 0e+00 | 0e+00 | 66 |
| GO:0008285 | negative regulation of cell population proliferation | 62/595 | 787/18614 | 0e+00 | 0e+00 | 62 |
| GO:0006935 | chemotaxis | 53/595 | 614/18614 | 0e+00 | 0e+00 | 53 |
| GO:0060078 | regulation of postsynaptic membrane potential | 24/595 | 148/18614 | 0e+00 | 0e+00 | 24 |
| GO:0042330 | taxis | 53/595 | 616/18614 | 0e+00 | 0e+00 | 53 |
| GO:0015833 | peptide transport | 32/595 | 259/18614 | 0e+00 | 0e+00 | 32 |
| GO:0060322 | head development | 64/595 | 831/18614 | 0e+00 | 0e+00 | 64 |
| GO:1903522 | regulation of blood circulation | 32/595 | 261/18614 | 0e+00 | 0e+00 | 32 |
| GO:0048732 | gland development | 43/595 | 441/18614 | 0e+00 | 0e+00 | 43 |
| GO:0043069 | negative regulation of programmed cell death | 69/595 | 940/18614 | 0e+00 | 0e+00 | 69 |
| GO:0090276 | regulation of peptide hormone secretion | 27/595 | 192/18614 | 0e+00 | 0e+00 | 27 |
| GO:0003018 | vascular process in circulatory system | 32/595 | 265/18614 | 0e+00 | 0e+00 | 32 |
| GO:0001525 | angiogenesis | 52/595 | 609/18614 | 0e+00 | 0e+00 | 52 |
| GO:0045785 | positive regulation of cell adhesion | 45/595 | 482/18614 | 0e+00 | 0e+00 | 45 |
| GO:1903530 | regulation of secretion by cell | 50/595 | 573/18614 | 0e+00 | 0e+00 | 50 |
| GO:0019725 | cellular homeostasis | 61/595 | 789/18614 | 0e+00 | 0e+00 | 61 |
| GO:0042391 | regulation of membrane potential | 42/595 | 433/18614 | 0e+00 | 0e+00 | 42 |
| GO:0099565 | chemical synaptic transmission, postsynaptic | 22/595 | 132/18614 | 0e+00 | 0e+00 | 22 |
| GO:0040007 | growth | 67/595 | 919/18614 | 0e+00 | 0e+00 | 67 |
| GO:0045597 | positive regulation of cell differentiation | 65/595 | 878/18614 | 0e+00 | 0e+00 | 65 |
| GO:0022409 | positive regulation of cell-cell adhesion | 35/595 | 321/18614 | 0e+00 | 0e+00 | 35 |
| GO:0007610 | behavior | 53/595 | 642/18614 | 0e+00 | 0e+00 | 53 |
| GO:0009410 | response to xenobiotic stimulus | 42/595 | 440/18614 | 0e+00 | 0e+00 | 42 |
| GO:0006954 | inflammatory response | 63/595 | 852/18614 | 0e+00 | 0e+00 | 63 |
| GO:0043269 | regulation of monoatomic ion transport | 50/595 | 599/18614 | 0e+00 | 0e+00 | 50 |
| GO:0051047 | positive regulation of secretion | 34/595 | 317/18614 | 0e+00 | 0e+00 | 34 |
| GO:0022407 | regulation of cell-cell adhesion | 44/595 | 491/18614 | 0e+00 | 0e+00 | 44 |
| GO:0030155 | regulation of cell adhesion | 60/595 | 803/18614 | 0e+00 | 0e+00 | 60 |
| GO:0048511 | rhythmic process | 33/595 | 303/18614 | 0e+00 | 0e+00 | 33 |
| GO:0007420 | brain development | 59/595 | 783/18614 | 0e+00 | 0e+00 | 59 |
| GO:0061564 | axon development | 43/595 | 479/18614 | 0e+00 | 0e+00 | 43 |
| GO:0007409 | axonogenesis | 40/595 | 427/18614 | 0e+00 | 0e+00 | 40 |
| GO:0043408 | regulation of MAPK cascade | 54/595 | 695/18614 | 0e+00 | 0e+00 | 54 |
| GO:0050673 | epithelial cell proliferation | 43/595 | 488/18614 | 0e+00 | 0e+00 | 43 |
| GO:0071692 | protein localization to extracellular region | 37/595 | 382/18614 | 0e+00 | 0e+00 | 37 |
| GO:0060079 | excitatory postsynaptic potential | 20/595 | 124/18614 | 0e+00 | 0e+00 | 20 |
| GO:0034097 | response to cytokine | 65/595 | 933/18614 | 0e+00 | 0e+00 | 65 |
| GO:0042327 | positive regulation of phosphorylation | 58/595 | 788/18614 | 0e+00 | 0e+00 | 58 |
| GO:0009306 | protein secretion | 36/595 | 373/18614 | 0e+00 | 0e+00 | 36 |
| GO:0048729 | tissue morphogenesis | 50/595 | 634/18614 | 0e+00 | 0e+00 | 50 |
| GO:0035592 | establishment of protein localization to extracellular region | 36/595 | 374/18614 | 0e+00 | 0e+00 | 36 |
| GO:1901653 | cellular response to peptide | 36/595 | 375/18614 | 0e+00 | 0e+00 | 36 |
| GO:0098609 | cell-cell adhesion | 65/595 | 950/18614 | 0e+00 | 0e+00 | 65 |
| GO:0030097 | hemopoiesis | 64/595 | 930/18614 | 0e+00 | 0e+00 | 64 |
| GO:0009991 | response to extracellular stimulus | 43/595 | 507/18614 | 0e+00 | 0e+00 | 43 |
| GO:0043270 | positive regulation of monoatomic ion transport | 27/595 | 231/18614 | 0e+00 | 0e+00 | 27 |
| GO:0022603 | regulation of anatomical structure morphogenesis | 64/595 | 933/18614 | 0e+00 | 0e+00 | 64 |
| GO:0006937 | regulation of muscle contraction | 23/595 | 173/18614 | 0e+00 | 0e+00 | 23 |
| GO:1902074 | response to salt | 36/595 | 383/18614 | 0e+00 | 0e+00 | 36 |
| GO:0050678 | regulation of epithelial cell proliferation | 38/595 | 419/18614 | 0e+00 | 0e+00 | 38 |
| GO:0071396 | cellular response to lipid | 48/595 | 608/18614 | 0e+00 | 0e+00 | 48 |
| GO:0000165 | MAPK cascade | 57/595 | 791/18614 | 0e+00 | 0e+00 | 57 |
| GO:0040017 | positive regulation of locomotion | 48/595 | 609/18614 | 0e+00 | 0e+00 | 48 |
| GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 27/595 | 234/18614 | 0e+00 | 0e+00 | 27 |
| GO:0055082 | intracellular chemical homeostasis | 52/595 | 689/18614 | 0e+00 | 0e+00 | 52 |
| GO:0070482 | response to oxygen levels | 33/595 | 333/18614 | 0e+00 | 0e+00 | 33 |
| GO:0031667 | response to nutrient levels | 41/595 | 477/18614 | 0e+00 | 0e+00 | 41 |
| GO:0048598 | embryonic morphogenesis | 48/595 | 613/18614 | 0e+00 | 0e+00 | 48 |
| GO:0048608 | reproductive structure development | 31/595 | 301/18614 | 0e+00 | 0e+00 | 31 |
| GO:2000147 | positive regulation of cell motility | 47/595 | 594/18614 | 0e+00 | 0e+00 | 47 |
| GO:0048871 | multicellular organismal-level homeostasis | 55/595 | 759/18614 | 0e+00 | 0e+00 | 55 |
| GO:0048545 | response to steroid hormone | 33/595 | 339/18614 | 0e+00 | 0e+00 | 33 |
| GO:0061458 | reproductive system development | 31/595 | 305/18614 | 0e+00 | 0e+00 | 31 |
| GO:1903532 | positive regulation of secretion by cell | 30/595 | 289/18614 | 0e+00 | 0e+00 | 30 |
| GO:0050900 | leukocyte migration | 36/595 | 393/18614 | 0e+00 | 0e+00 | 36 |
| GO:0036293 | response to decreased oxygen levels | 31/595 | 306/18614 | 0e+00 | 0e+00 | 31 |
| GO:0050804 | modulation of chemical synaptic transmission | 41/595 | 487/18614 | 0e+00 | 0e+00 | 41 |
| GO:0099177 | regulation of trans-synaptic signaling | 41/595 | 488/18614 | 0e+00 | 0e+00 | 41 |
| GO:0007159 | leukocyte cell-cell adhesion | 37/595 | 415/18614 | 0e+00 | 0e+00 | 37 |
| GO:0001666 | response to hypoxia | 30/595 | 293/18614 | 0e+00 | 0e+00 | 30 |
| GO:0030335 | positive regulation of cell migration | 45/595 | 569/18614 | 0e+00 | 0e+00 | 45 |
| GO:0031281 | positive regulation of cyclase activity | 11/595 | 39/18614 | 0e+00 | 0e+00 | 11 |
| GO:0045766 | positive regulation of angiogenesis | 23/595 | 185/18614 | 0e+00 | 0e+00 | 23 |
| GO:1904018 | positive regulation of vasculature development | 23/595 | 185/18614 | 0e+00 | 0e+00 | 23 |
| GO:0042060 | wound healing | 38/595 | 439/18614 | 0e+00 | 0e+00 | 38 |
| GO:0048667 | cell morphogenesis involved in neuron differentiation | 44/595 | 555/18614 | 0e+00 | 0e+00 | 44 |
| GO:0001656 | metanephros development | 16/595 | 92/18614 | 0e+00 | 0e+00 | 16 |
| GO:0008217 | regulation of blood pressure | 23/595 | 187/18614 | 0e+00 | 0e+00 | 23 |
| GO:0090257 | regulation of muscle system process | 27/595 | 254/18614 | 0e+00 | 0e+00 | 27 |
| GO:0010720 | positive regulation of cell development | 37/595 | 432/18614 | 0e+00 | 0e+00 | 37 |
| GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 28/595 | 273/18614 | 0e+00 | 0e+00 | 28 |
| GO:0097190 | apoptotic signaling pathway | 46/595 | 608/18614 | 0e+00 | 0e+00 | 46 |
| GO:0002793 | positive regulation of peptide secretion | 17/595 | 109/18614 | 0e+00 | 0e+00 | 17 |
| GO:0045109 | intermediate filament organization | 14/595 | 73/18614 | 0e+00 | 0e+00 | 14 |
| GO:0007411 | axon guidance | 25/595 | 225/18614 | 0e+00 | 0e+00 | 25 |
| GO:0097485 | neuron projection guidance | 25/595 | 225/18614 | 0e+00 | 0e+00 | 25 |
| GO:0030879 | mammary gland development | 19/595 | 136/18614 | 0e+00 | 0e+00 | 19 |
| GO:0090066 | regulation of anatomical structure size | 40/595 | 492/18614 | 0e+00 | 0e+00 | 40 |
| GO:0032880 | regulation of protein localization | 58/595 | 863/18614 | 0e+00 | 0e+00 | 58 |
| GO:0003015 | heart process | 27/595 | 259/18614 | 0e+00 | 0e+00 | 27 |
| GO:0031960 | response to corticosteroid | 21/595 | 166/18614 | 0e+00 | 0e+00 | 21 |
| GO:0008016 | regulation of heart contraction | 24/595 | 213/18614 | 0e+00 | 0e+00 | 24 |
| GO:0001934 | positive regulation of protein phosphorylation | 51/595 | 720/18614 | 0e+00 | 0e+00 | 51 |
| GO:0045471 | response to ethanol | 18/595 | 126/18614 | 0e+00 | 0e+00 | 18 |
| GO:0032989 | cellular component morphogenesis | 53/595 | 767/18614 | 0e+00 | 0e+00 | 53 |
| GO:0042593 | glucose homeostasis | 26/595 | 248/18614 | 0e+00 | 0e+00 | 26 |
| GO:0060284 | regulation of cell development | 56/595 | 833/18614 | 0e+00 | 0e+00 | 56 |
| GO:0033500 | carbohydrate homeostasis | 26/595 | 249/18614 | 0e+00 | 0e+00 | 26 |
| GO:0097435 | supramolecular fiber organization | 55/595 | 812/18614 | 0e+00 | 0e+00 | 55 |
| GO:0043434 | response to peptide hormone | 36/595 | 427/18614 | 0e+00 | 0e+00 | 36 |
| GO:0007548 | sex differentiation | 28/595 | 283/18614 | 0e+00 | 0e+00 | 28 |
| GO:0007584 | response to nutrient | 20/595 | 156/18614 | 0e+00 | 0e+00 | 20 |
| GO:0007589 | body fluid secretion | 15/595 | 89/18614 | 0e+00 | 0e+00 | 15 |
| GO:0051384 | response to glucocorticoid | 19/595 | 142/18614 | 0e+00 | 0e+00 | 19 |
| GO:0000904 | cell morphogenesis involved in differentiation | 46/595 | 625/18614 | 0e+00 | 0e+00 | 46 |
| GO:0002521 | leukocyte differentiation | 45/595 | 605/18614 | 0e+00 | 0e+00 | 45 |
| GO:0010035 | response to inorganic substance | 43/595 | 567/18614 | 0e+00 | 0e+00 | 43 |
| GO:0048589 | developmental growth | 47/595 | 649/18614 | 0e+00 | 0e+00 | 47 |
| GO:0008544 | epidermis development | 33/595 | 375/18614 | 0e+00 | 0e+00 | 33 |
| GO:1903037 | regulation of leukocyte cell-cell adhesion | 33/595 | 378/18614 | 0e+00 | 0e+00 | 33 |
| GO:0120039 | plasma membrane bounded cell projection morphogenesis | 46/595 | 633/18614 | 0e+00 | 0e+00 | 46 |
| GO:0030001 | metal ion transport | 59/595 | 911/18614 | 0e+00 | 0e+00 | 59 |
| GO:0045104 | intermediate filament cytoskeleton organization | 15/595 | 92/18614 | 0e+00 | 0e+00 | 15 |
| GO:0032496 | response to lipopolysaccharide | 31/595 | 345/18614 | 0e+00 | 0e+00 | 31 |
| GO:0045103 | intermediate filament-based process | 15/595 | 93/18614 | 0e+00 | 0e+00 | 15 |
| GO:0048812 | neuron projection morphogenesis | 45/595 | 617/18614 | 0e+00 | 0e+00 | 45 |
| GO:0048858 | cell projection morphogenesis | 46/595 | 638/18614 | 0e+00 | 0e+00 | 46 |
| GO:0045664 | regulation of neuron differentiation | 22/595 | 194/18614 | 0e+00 | 0e+00 | 22 |
| GO:0009617 | response to bacterium | 50/595 | 725/18614 | 0e+00 | 0e+00 | 50 |
| GO:0015837 | amine transport | 16/595 | 107/18614 | 0e+00 | 0e+00 | 16 |
| GO:0090277 | positive regulation of peptide hormone secretion | 16/595 | 107/18614 | 0e+00 | 0e+00 | 16 |
| GO:0002237 | response to molecule of bacterial origin | 32/595 | 366/18614 | 0e+00 | 0e+00 | 32 |
| GO:0071407 | cellular response to organic cyclic compound | 43/595 | 580/18614 | 0e+00 | 0e+00 | 43 |
| GO:0040008 | regulation of growth | 45/595 | 621/18614 | 0e+00 | 0e+00 | 45 |
| GO:0042476 | odontogenesis | 18/595 | 135/18614 | 0e+00 | 0e+00 | 18 |
| GO:0045765 | regulation of angiogenesis | 31/595 | 349/18614 | 0e+00 | 0e+00 | 31 |
| GO:0060341 | regulation of cellular localization | 61/595 | 969/18614 | 0e+00 | 0e+00 | 61 |
| GO:0031644 | regulation of nervous system process | 19/595 | 150/18614 | 0e+00 | 0e+00 | 19 |
| GO:0048771 | tissue remodeling | 21/595 | 181/18614 | 0e+00 | 0e+00 | 21 |
| GO:0030073 | insulin secretion | 22/595 | 197/18614 | 0e+00 | 0e+00 | 22 |
| GO:0051349 | positive regulation of lyase activity | 10/595 | 40/18614 | 0e+00 | 0e+00 | 10 |
| GO:0045776 | negative regulation of blood pressure | 11/595 | 50/18614 | 0e+00 | 0e+00 | 11 |
| GO:0006941 | striated muscle contraction | 21/595 | 182/18614 | 0e+00 | 0e+00 | 21 |
| GO:0060047 | heart contraction | 25/595 | 247/18614 | 0e+00 | 0e+00 | 25 |
| GO:0046887 | positive regulation of hormone secretion | 18/595 | 138/18614 | 0e+00 | 0e+00 | 18 |
| GO:0009612 | response to mechanical stimulus | 23/595 | 215/18614 | 0e+00 | 0e+00 | 23 |
| GO:1901342 | regulation of vasculature development | 31/595 | 355/18614 | 0e+00 | 0e+00 | 31 |
| GO:0044706 | multi-multicellular organism process | 23/595 | 216/18614 | 0e+00 | 0e+00 | 23 |
| GO:0032870 | cellular response to hormone stimulus | 44/595 | 611/18614 | 0e+00 | 0e+00 | 44 |
| GO:0051952 | regulation of amine transport | 15/595 | 98/18614 | 0e+00 | 0e+00 | 15 |
| GO:0007423 | sensory organ development | 42/595 | 571/18614 | 0e+00 | 0e+00 | 42 |
| GO:0006959 | humoral immune response | 25/595 | 250/18614 | 0e+00 | 0e+00 | 25 |
| GO:0007189 | adenylate cyclase-activating G protein-coupled receptor signaling pathway | 18/595 | 140/18614 | 0e+00 | 0e+00 | 18 |
| GO:0043068 | positive regulation of programmed cell death | 41/595 | 553/18614 | 0e+00 | 0e+00 | 41 |
| GO:0060349 | bone morphogenesis | 15/595 | 99/18614 | 0e+00 | 0e+00 | 15 |
| GO:0060348 | bone development | 24/595 | 235/18614 | 0e+00 | 0e+00 | 24 |
| GO:0002252 | immune effector process | 45/595 | 637/18614 | 0e+00 | 0e+00 | 45 |
| GO:0032990 | cell part morphogenesis | 46/595 | 658/18614 | 0e+00 | 0e+00 | 46 |
| GO:0003014 | renal system process | 17/595 | 127/18614 | 0e+00 | 0e+00 | 17 |
| GO:0032755 | positive regulation of interleukin-6 production | 15/595 | 100/18614 | 0e+00 | 0e+00 | 15 |
| GO:0031347 | regulation of defense response | 51/595 | 767/18614 | 0e+00 | 0e+00 | 51 |
| GO:0035296 | regulation of tube diameter | 18/595 | 142/18614 | 0e+00 | 0e+00 | 18 |
| GO:0097746 | blood vessel diameter maintenance | 18/595 | 142/18614 | 0e+00 | 0e+00 | 18 |
| GO:0034762 | regulation of transmembrane transport | 44/595 | 619/18614 | 0e+00 | 0e+00 | 44 |
| GO:0071345 | cellular response to cytokine stimulus | 54/595 | 834/18614 | 0e+00 | 0e+00 | 54 |
| GO:0034765 | regulation of monoatomic ion transmembrane transport | 37/595 | 478/18614 | 0e+00 | 0e+00 | 37 |
| GO:0035150 | regulation of tube size | 18/595 | 143/18614 | 0e+00 | 0e+00 | 18 |
| GO:0097094 | craniofacial suture morphogenesis | 7/595 | 18/18614 | 0e+00 | 0e+00 | 7 |
| GO:0031099 | regeneration | 21/595 | 190/18614 | 0e+00 | 0e+00 | 21 |
| GO:0019932 | second-messenger-mediated signaling | 27/595 | 292/18614 | 0e+00 | 0e+00 | 27 |
| GO:0000902 | cell morphogenesis | 58/595 | 929/18614 | 0e+00 | 0e+00 | 58 |
| GO:0050708 | regulation of protein secretion | 26/595 | 275/18614 | 0e+00 | 0e+00 | 26 |
| GO:0007611 | learning or memory | 26/595 | 276/18614 | 0e+00 | 0e+00 | 26 |
| GO:0032102 | negative regulation of response to external stimulus | 35/595 | 446/18614 | 0e+00 | 0e+00 | 35 |
| GO:0002064 | epithelial cell development | 22/595 | 210/18614 | 0e+00 | 0e+00 | 22 |
| GO:0007507 | heart development | 43/595 | 611/18614 | 0e+00 | 0e+00 | 43 |
| GO:0050796 | regulation of insulin secretion | 19/595 | 163/18614 | 0e+00 | 0e+00 | 19 |
| GO:0009268 | response to pH | 10/595 | 45/18614 | 0e+00 | 0e+00 | 10 |
| GO:0007204 | positive regulation of cytosolic calcium ion concentration | 20/595 | 179/18614 | 0e+00 | 0e+00 | 20 |
| GO:0033674 | positive regulation of kinase activity | 34/595 | 430/18614 | 0e+00 | 0e+00 | 34 |
| GO:0001906 | cell killing | 21/595 | 197/18614 | 0e+00 | 0e+00 | 21 |
| GO:0042110 | T cell activation | 40/595 | 554/18614 | 0e+00 | 0e+00 | 40 |
| GO:0042063 | gliogenesis | 28/595 | 320/18614 | 0e+00 | 0e+00 | 28 |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 44/595 | 639/18614 | 0e+00 | 0e+00 | 44 |
| GO:0045321 | leukocyte activation | 58/595 | 948/18614 | 0e+00 | 0e+00 | 58 |
| GO:0050870 | positive regulation of T cell activation | 24/595 | 249/18614 | 0e+00 | 0e+00 | 24 |
| GO:0043065 | positive regulation of apoptotic process | 39/595 | 536/18614 | 0e+00 | 0e+00 | 39 |
| GO:0006874 | intracellular calcium ion homeostasis | 27/595 | 303/18614 | 0e+00 | 0e+00 | 27 |
| GO:0010942 | positive regulation of cell death | 43/595 | 621/18614 | 0e+00 | 0e+00 | 43 |
| GO:0051223 | regulation of protein transport | 38/595 | 518/18614 | 0e+00 | 0e+00 | 38 |
| GO:2001233 | regulation of apoptotic signaling pathway | 31/595 | 381/18614 | 0e+00 | 0e+00 | 31 |
| GO:0034764 | positive regulation of transmembrane transport | 23/595 | 235/18614 | 0e+00 | 0e+00 | 23 |
| GO:0003180 | aortic valve morphogenesis | 9/595 | 38/18614 | 0e+00 | 1e-04 | 9 |
| GO:0051251 | positive regulation of lymphocyte activation | 28/595 | 327/18614 | 0e+00 | 1e-04 | 28 |
| GO:0055074 | calcium ion homeostasis | 28/595 | 327/18614 | 0e+00 | 1e-04 | 28 |
| GO:0010959 | regulation of metal ion transport | 33/595 | 423/18614 | 0e+00 | 1e-04 | 33 |
| GO:0006942 | regulation of striated muscle contraction | 14/595 | 97/18614 | 0e+00 | 1e-04 | 14 |
| GO:0007565 | female pregnancy | 20/595 | 187/18614 | 0e+00 | 1e-04 | 20 |
| GO:0031175 | neuron projection development | 58/595 | 962/18614 | 0e+00 | 1e-04 | 58 |
| GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 18/595 | 156/18614 | 0e+00 | 1e-04 | 18 |
| GO:0034330 | cell junction organization | 48/595 | 739/18614 | 0e+00 | 1e-04 | 48 |
| GO:0045933 | positive regulation of muscle contraction | 10/595 | 49/18614 | 0e+00 | 1e-04 | 10 |
| GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 22/595 | 222/18614 | 0e+00 | 1e-04 | 22 |
| GO:0061448 | connective tissue development | 25/595 | 275/18614 | 0e+00 | 1e-04 | 25 |
| GO:0050905 | neuromuscular process | 18/595 | 157/18614 | 0e+00 | 1e-04 | 18 |
| GO:0009913 | epidermal cell differentiation | 23/595 | 240/18614 | 0e+00 | 1e-04 | 23 |
| GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 14/595 | 99/18614 | 0e+00 | 1e-04 | 14 |
| GO:0006939 | smooth muscle contraction | 15/595 | 113/18614 | 0e+00 | 1e-04 | 15 |
| GO:0007200 | phospholipase C-activating G protein-coupled receptor signaling pathway | 15/595 | 113/18614 | 0e+00 | 1e-04 | 15 |
| GO:0031279 | regulation of cyclase activity | 11/595 | 61/18614 | 0e+00 | 1e-04 | 11 |
| GO:0044703 | multi-organism reproductive process | 21/595 | 207/18614 | 0e+00 | 1e-04 | 21 |
| GO:0015844 | monoamine transport | 13/595 | 86/18614 | 0e+00 | 1e-04 | 13 |
| GO:0050679 | positive regulation of epithelial cell proliferation | 22/595 | 225/18614 | 0e+00 | 1e-04 | 22 |
| GO:0034767 | positive regulation of monoatomic ion transmembrane transport | 19/595 | 175/18614 | 0e+00 | 1e-04 | 19 |
| GO:0070372 | regulation of ERK1 and ERK2 cascade | 27/595 | 315/18614 | 0e+00 | 1e-04 | 27 |
| GO:0006873 | intracellular monoatomic ion homeostasis | 37/595 | 513/18614 | 0e+00 | 1e-04 | 37 |
| GO:0050890 | cognition | 27/595 | 317/18614 | 0e+00 | 1e-04 | 27 |
| GO:1903131 | mononuclear cell differentiation | 35/595 | 474/18614 | 0e+00 | 1e-04 | 35 |
| GO:0045165 | cell fate commitment | 25/595 | 281/18614 | 0e+00 | 1e-04 | 25 |
| GO:0048880 | sensory system development | 31/595 | 395/18614 | 0e+00 | 1e-04 | 31 |
| GO:0006816 | calcium ion transport | 34/595 | 455/18614 | 0e+00 | 1e-04 | 34 |
| GO:0002696 | positive regulation of leukocyte activation | 30/595 | 377/18614 | 0e+00 | 1e-04 | 30 |
| GO:0060485 | mesenchyme development | 27/595 | 320/18614 | 0e+00 | 1e-04 | 27 |
| GO:0061061 | muscle structure development | 45/595 | 689/18614 | 0e+00 | 1e-04 | 45 |
| GO:0002009 | morphogenesis of an epithelium | 37/595 | 519/18614 | 0e+00 | 1e-04 | 37 |
| GO:0071300 | cellular response to retinoic acid | 11/595 | 64/18614 | 0e+00 | 1e-04 | 11 |
| GO:0051048 | negative regulation of secretion | 19/595 | 180/18614 | 0e+00 | 1e-04 | 19 |
| GO:0098771 | inorganic ion homeostasis | 38/595 | 542/18614 | 0e+00 | 1e-04 | 38 |
| GO:0070201 | regulation of establishment of protein localization | 38/595 | 543/18614 | 0e+00 | 1e-04 | 38 |
| GO:0007595 | lactation | 9/595 | 42/18614 | 0e+00 | 1e-04 | 9 |
| GO:0046888 | negative regulation of hormone secretion | 11/595 | 65/18614 | 0e+00 | 1e-04 | 11 |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 22/595 | 233/18614 | 0e+00 | 1e-04 | 22 |
| GO:0030003 | intracellular monoatomic cation homeostasis | 36/595 | 504/18614 | 0e+00 | 1e-04 | 36 |
| GO:0097305 | response to alcohol | 23/595 | 252/18614 | 0e+00 | 1e-04 | 23 |
| GO:0042129 | regulation of T cell proliferation | 19/595 | 183/18614 | 0e+00 | 1e-04 | 19 |
| GO:0003176 | aortic valve development | 9/595 | 43/18614 | 0e+00 | 1e-04 | 9 |
| GO:0032735 | positive regulation of interleukin-12 production | 9/595 | 43/18614 | 0e+00 | 1e-04 | 9 |
| GO:0051954 | positive regulation of amine transport | 9/595 | 43/18614 | 0e+00 | 1e-04 | 9 |
| GO:1904062 | regulation of monoatomic cation transmembrane transport | 28/595 | 346/18614 | 0e+00 | 1e-04 | 28 |
| GO:0043588 | skin development | 26/595 | 308/18614 | 0e+00 | 1e-04 | 26 |
| GO:0001654 | eye development | 30/595 | 385/18614 | 0e+00 | 1e-04 | 30 |
| GO:0060452 | positive regulation of cardiac muscle contraction | 5/595 | 10/18614 | 0e+00 | 1e-04 | 5 |
| GO:0032868 | response to insulin | 24/595 | 272/18614 | 0e+00 | 1e-04 | 24 |
| GO:1904064 | positive regulation of cation transmembrane transport | 17/595 | 152/18614 | 0e+00 | 1e-04 | 17 |
| GO:0032526 | response to retinoic acid | 14/595 | 107/18614 | 0e+00 | 2e-04 | 14 |
| GO:0006836 | neurotransmitter transport | 20/595 | 202/18614 | 0e+00 | 2e-04 | 20 |
| GO:0001819 | positive regulation of cytokine production | 35/595 | 489/18614 | 0e+00 | 2e-04 | 35 |
| GO:0051966 | regulation of synaptic transmission, glutamatergic | 12/595 | 80/18614 | 0e+00 | 2e-04 | 12 |
| GO:0051098 | regulation of binding | 29/595 | 369/18614 | 0e+00 | 2e-04 | 29 |
| GO:0051216 | cartilage development | 20/595 | 203/18614 | 0e+00 | 2e-04 | 20 |
| GO:0150063 | visual system development | 30/595 | 389/18614 | 0e+00 | 2e-04 | 30 |
| GO:0060048 | cardiac muscle contraction | 16/595 | 138/18614 | 0e+00 | 2e-04 | 16 |
| GO:0050776 | regulation of immune response | 52/595 | 863/18614 | 0e+00 | 2e-04 | 52 |
| GO:0050670 | regulation of lymphocyte proliferation | 22/595 | 239/18614 | 0e+00 | 2e-04 | 22 |
| GO:0007517 | muscle organ development | 28/595 | 351/18614 | 0e+00 | 2e-04 | 28 |
| GO:0048562 | embryonic organ morphogenesis | 25/595 | 294/18614 | 0e+00 | 2e-04 | 25 |
| GO:0034114 | regulation of heterotypic cell-cell adhesion | 7/595 | 25/18614 | 0e+00 | 2e-04 | 7 |
| GO:0061138 | morphogenesis of a branching epithelium | 19/595 | 188/18614 | 0e+00 | 2e-04 | 19 |
| GO:0030198 | extracellular matrix organization | 26/595 | 314/18614 | 0e+00 | 2e-04 | 26 |
| GO:0048568 | embryonic organ development | 33/595 | 453/18614 | 0e+00 | 2e-04 | 33 |
| GO:0097529 | myeloid leukocyte migration | 22/595 | 241/18614 | 0e+00 | 2e-04 | 22 |
| GO:0043062 | extracellular structure organization | 26/595 | 315/18614 | 0e+00 | 2e-04 | 26 |
| GO:0001501 | skeletal system development | 37/595 | 537/18614 | 0e+00 | 2e-04 | 37 |
| GO:1903531 | negative regulation of secretion by cell | 17/595 | 156/18614 | 0e+00 | 2e-04 | 17 |
| GO:0055080 | monoatomic cation homeostasis | 40/595 | 602/18614 | 0e+00 | 2e-04 | 40 |
| GO:0050867 | positive regulation of cell activation | 30/595 | 394/18614 | 0e+00 | 2e-04 | 30 |
| GO:0010332 | response to gamma radiation | 10/595 | 57/18614 | 0e+00 | 2e-04 | 10 |
| GO:0050778 | positive regulation of immune response | 44/595 | 691/18614 | 0e+00 | 2e-04 | 44 |
| GO:1903706 | regulation of hemopoiesis | 31/595 | 415/18614 | 0e+00 | 2e-04 | 31 |
| GO:0045229 | external encapsulating structure organization | 26/595 | 317/18614 | 0e+00 | 2e-04 | 26 |
| GO:0032944 | regulation of mononuclear cell proliferation | 22/595 | 243/18614 | 0e+00 | 2e-04 | 22 |
| GO:0046649 | lymphocyte activation | 48/595 | 782/18614 | 0e+00 | 2e-04 | 48 |
| GO:0030216 | keratinocyte differentiation | 18/595 | 174/18614 | 0e+00 | 2e-04 | 18 |
| GO:0003007 | heart morphogenesis | 23/595 | 262/18614 | 0e+00 | 2e-04 | 23 |
| GO:0002026 | regulation of the force of heart contraction | 7/595 | 26/18614 | 0e+00 | 2e-04 | 7 |
| GO:0050863 | regulation of T cell activation | 29/595 | 377/18614 | 0e+00 | 2e-04 | 29 |
| GO:0043010 | camera-type eye development | 27/595 | 338/18614 | 0e+00 | 2e-04 | 27 |
| GO:1902105 | regulation of leukocyte differentiation | 26/595 | 319/18614 | 0e+00 | 2e-04 | 26 |
| GO:0009755 | hormone-mediated signaling pathway | 19/595 | 192/18614 | 0e+00 | 2e-04 | 19 |
| GO:0035249 | synaptic transmission, glutamatergic | 14/595 | 112/18614 | 0e+00 | 2e-04 | 14 |
| GO:0097191 | extrinsic apoptotic signaling pathway | 21/595 | 227/18614 | 0e+00 | 2e-04 | 21 |
| GO:0008406 | gonad development | 21/595 | 228/18614 | 0e+00 | 2e-04 | 21 |
| GO:0071363 | cellular response to growth factor stimulus | 45/595 | 720/18614 | 0e+00 | 2e-04 | 45 |
| GO:0042220 | response to cocaine | 9/595 | 47/18614 | 0e+00 | 3e-04 | 9 |
| GO:1905314 | semi-lunar valve development | 9/595 | 47/18614 | 0e+00 | 3e-04 | 9 |
| GO:0098657 | import into cell | 23/595 | 265/18614 | 0e+00 | 3e-04 | 23 |
| GO:0070371 | ERK1 and ERK2 cascade | 27/595 | 341/18614 | 0e+00 | 3e-04 | 27 |
| GO:1905114 | cell surface receptor signaling pathway involved in cell-cell signaling | 39/595 | 589/18614 | 0e+00 | 3e-04 | 39 |
| GO:0031348 | negative regulation of defense response | 24/595 | 284/18614 | 0e+00 | 3e-04 | 24 |
| GO:0031102 | neuron projection regeneration | 10/595 | 59/18614 | 0e+00 | 3e-04 | 10 |
| GO:0050801 | monoatomic ion homeostasis | 40/595 | 612/18614 | 0e+00 | 3e-04 | 40 |
| GO:0051928 | positive regulation of calcium ion transport | 15/595 | 129/18614 | 0e+00 | 3e-04 | 15 |
| GO:0032682 | negative regulation of chemokine production | 7/595 | 27/18614 | 0e+00 | 3e-04 | 7 |
| GO:0072207 | metanephric epithelium development | 7/595 | 27/18614 | 0e+00 | 3e-04 | 7 |
| GO:0032635 | interleukin-6 production | 18/595 | 178/18614 | 0e+00 | 3e-04 | 18 |
| GO:0032675 | regulation of interleukin-6 production | 18/595 | 178/18614 | 0e+00 | 3e-04 | 18 |
| GO:0019216 | regulation of lipid metabolic process | 27/595 | 344/18614 | 0e+00 | 3e-04 | 27 |
| GO:0007369 | gastrulation | 19/595 | 196/18614 | 0e+00 | 3e-04 | 19 |
| GO:0046717 | acid secretion | 9/595 | 48/18614 | 0e+00 | 3e-04 | 9 |
| GO:0072073 | kidney epithelium development | 16/595 | 146/18614 | 0e+00 | 3e-04 | 16 |
| GO:0003179 | heart valve morphogenesis | 10/595 | 60/18614 | 0e+00 | 3e-04 | 10 |
| GO:0003170 | heart valve development | 11/595 | 73/18614 | 0e+00 | 3e-04 | 11 |
| GO:0051937 | catecholamine transport | 11/595 | 73/18614 | 0e+00 | 3e-04 | 11 |
| GO:0070848 | response to growth factor | 46/595 | 751/18614 | 0e+00 | 3e-04 | 46 |
| GO:0045137 | development of primary sexual characteristics | 21/595 | 233/18614 | 0e+00 | 3e-04 | 21 |
| GO:0048708 | astrocyte differentiation | 12/595 | 87/18614 | 0e+00 | 3e-04 | 12 |
| GO:0071496 | cellular response to external stimulus | 26/595 | 327/18614 | 0e+00 | 3e-04 | 26 |
| GO:0071375 | cellular response to peptide hormone stimulus | 25/595 | 308/18614 | 0e+00 | 3e-04 | 25 |
| GO:0010038 | response to metal ion | 28/595 | 367/18614 | 0e+00 | 3e-04 | 28 |
| GO:0046849 | bone remodeling | 12/595 | 88/18614 | 0e+00 | 4e-04 | 12 |
| GO:0010001 | glial cell differentiation | 21/595 | 235/18614 | 0e+00 | 4e-04 | 21 |
| GO:0018108 | peptidyl-tyrosine phosphorylation | 28/595 | 370/18614 | 0e+00 | 4e-04 | 28 |
| GO:0030856 | regulation of epithelial cell differentiation | 17/595 | 166/18614 | 0e+00 | 4e-04 | 17 |
| GO:0009266 | response to temperature stimulus | 18/595 | 183/18614 | 0e+00 | 4e-04 | 18 |
| GO:0001935 | endothelial cell proliferation | 19/595 | 201/18614 | 0e+00 | 4e-04 | 19 |
| GO:1902107 | positive regulation of leukocyte differentiation | 18/595 | 184/18614 | 0e+00 | 4e-04 | 18 |
| GO:1903708 | positive regulation of hemopoiesis | 18/595 | 184/18614 | 0e+00 | 4e-04 | 18 |
| GO:0018212 | peptidyl-tyrosine modification | 28/595 | 372/18614 | 0e+00 | 4e-04 | 28 |
| GO:0007601 | visual perception | 20/595 | 220/18614 | 0e+00 | 4e-04 | 20 |
| GO:0001936 | regulation of endothelial cell proliferation | 18/595 | 185/18614 | 0e+00 | 4e-04 | 18 |
| GO:0045596 | negative regulation of cell differentiation | 44/595 | 717/18614 | 0e+00 | 4e-04 | 44 |
| GO:0033555 | multicellular organismal response to stress | 12/595 | 90/18614 | 0e+00 | 4e-04 | 12 |
| GO:0060562 | epithelial tube morphogenesis | 26/595 | 334/18614 | 0e+00 | 4e-04 | 26 |
| GO:0001763 | morphogenesis of a branching structure | 19/595 | 203/18614 | 0e+00 | 4e-04 | 19 |
| GO:0051101 | regulation of DNA binding | 14/595 | 120/18614 | 0e+00 | 4e-04 | 14 |
| GO:0098660 | inorganic ion transmembrane transport | 53/595 | 926/18614 | 0e+00 | 4e-04 | 53 |
| GO:0042102 | positive regulation of T cell proliferation | 13/595 | 105/18614 | 0e+00 | 4e-04 | 13 |
| GO:1903169 | regulation of calcium ion transmembrane transport | 18/595 | 186/18614 | 0e+00 | 5e-04 | 18 |
| GO:0015850 | organic hydroxy compound transport | 24/595 | 296/18614 | 0e+00 | 5e-04 | 24 |
| GO:0007568 | aging | 17/595 | 169/18614 | 0e+00 | 5e-04 | 17 |
| GO:0031401 | positive regulation of protein modification process | 55/595 | 976/18614 | 0e+00 | 5e-04 | 55 |
| GO:0050728 | negative regulation of inflammatory response | 18/595 | 187/18614 | 0e+00 | 5e-04 | 18 |
| GO:0032615 | interleukin-12 production | 10/595 | 64/18614 | 0e+00 | 5e-04 | 10 |
| GO:0032655 | regulation of interleukin-12 production | 10/595 | 64/18614 | 0e+00 | 5e-04 | 10 |
| GO:0050806 | positive regulation of synaptic transmission | 17/595 | 170/18614 | 0e+00 | 5e-04 | 17 |
| GO:0008277 | regulation of G protein-coupled receptor signaling pathway | 15/595 | 137/18614 | 0e+00 | 5e-04 | 15 |
| GO:0050865 | regulation of cell activation | 41/595 | 655/18614 | 0e+00 | 5e-04 | 41 |
| GO:0051347 | positive regulation of transferase activity | 35/595 | 524/18614 | 0e+00 | 5e-04 | 35 |
| GO:0022602 | ovulation cycle process | 9/595 | 52/18614 | 0e+00 | 5e-04 | 9 |
| GO:0031103 | axon regeneration | 9/595 | 52/18614 | 0e+00 | 5e-04 | 9 |
| GO:0007596 | blood coagulation | 20/595 | 224/18614 | 0e+00 | 5e-04 | 20 |
| GO:0050953 | sensory perception of light stimulus | 20/595 | 224/18614 | 0e+00 | 5e-04 | 20 |
| GO:0031668 | cellular response to extracellular stimulus | 22/595 | 261/18614 | 0e+00 | 5e-04 | 22 |
| GO:0051051 | negative regulation of transport | 33/595 | 483/18614 | 0e+00 | 5e-04 | 33 |
| GO:0071466 | cellular response to xenobiotic stimulus | 18/595 | 189/18614 | 0e+00 | 5e-04 | 18 |
| GO:0051339 | regulation of lyase activity | 10/595 | 65/18614 | 0e+00 | 5e-04 | 10 |
| GO:1904427 | positive regulation of calcium ion transmembrane transport | 12/595 | 93/18614 | 0e+00 | 6e-04 | 12 |
| GO:0001894 | tissue homeostasis | 22/595 | 263/18614 | 0e+00 | 6e-04 | 22 |
| GO:0060249 | anatomical structure homeostasis | 22/595 | 263/18614 | 0e+00 | 6e-04 | 22 |
| GO:0051090 | regulation of DNA-binding transcription factor activity | 32/595 | 465/18614 | 0e+00 | 6e-04 | 32 |
| GO:0002685 | regulation of leukocyte migration | 20/595 | 227/18614 | 0e+00 | 6e-04 | 20 |
| GO:0045762 | positive regulation of adenylate cyclase activity | 7/595 | 31/18614 | 0e+00 | 6e-04 | 7 |
| GO:0048754 | branching morphogenesis of an epithelial tube | 16/595 | 157/18614 | 0e+00 | 6e-04 | 16 |
| GO:0007218 | neuropeptide signaling pathway | 13/595 | 109/18614 | 0e+00 | 6e-04 | 13 |
| GO:0032890 | regulation of organic acid transport | 11/595 | 80/18614 | 0e+00 | 6e-04 | 11 |
| GO:0048644 | muscle organ morphogenesis | 11/595 | 80/18614 | 0e+00 | 6e-04 | 11 |
| GO:0048863 | stem cell differentiation | 21/595 | 247/18614 | 0e+00 | 7e-04 | 21 |
| GO:0051924 | regulation of calcium ion transport | 22/595 | 266/18614 | 0e+00 | 7e-04 | 22 |
| GO:1903829 | positive regulation of protein localization | 32/595 | 468/18614 | 0e+00 | 7e-04 | 32 |
| GO:0060537 | muscle tissue development | 30/595 | 426/18614 | 0e+00 | 7e-04 | 30 |
| GO:0050817 | coagulation | 20/595 | 229/18614 | 0e+00 | 7e-04 | 20 |
| GO:0009620 | response to fungus | 10/595 | 67/18614 | 0e+00 | 7e-04 | 10 |
| GO:0001505 | regulation of neurotransmitter levels | 19/595 | 211/18614 | 1e-04 | 7e-04 | 19 |
| GO:0033630 | positive regulation of cell adhesion mediated by integrin | 6/595 | 22/18614 | 1e-04 | 7e-04 | 6 |
| GO:0003206 | cardiac chamber morphogenesis | 14/595 | 126/18614 | 1e-04 | 7e-04 | 14 |
| GO:0003231 | cardiac ventricle development | 14/595 | 126/18614 | 1e-04 | 7e-04 | 14 |
| GO:0046651 | lymphocyte proliferation | 24/595 | 306/18614 | 1e-04 | 7e-04 | 24 |
| GO:0007599 | hemostasis | 20/595 | 230/18614 | 1e-04 | 7e-04 | 20 |
| GO:0031669 | cellular response to nutrient levels | 20/595 | 230/18614 | 1e-04 | 7e-04 | 20 |
| GO:0045860 | positive regulation of protein kinase activity | 27/595 | 366/18614 | 1e-04 | 7e-04 | 27 |
| GO:0070663 | regulation of leukocyte proliferation | 22/595 | 268/18614 | 1e-04 | 7e-04 | 22 |
| GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway | 7/595 | 32/18614 | 1e-04 | 7e-04 | 7 |
| GO:0001503 | ossification | 30/595 | 429/18614 | 1e-04 | 7e-04 | 30 |
| GO:0018209 | peptidyl-serine modification | 25/595 | 327/18614 | 1e-04 | 7e-04 | 25 |
| GO:0050805 | negative regulation of synaptic transmission | 9/595 | 55/18614 | 1e-04 | 7e-04 | 9 |
| GO:0042098 | T cell proliferation | 19/595 | 213/18614 | 1e-04 | 7e-04 | 19 |
| GO:0090596 | sensory organ morphogenesis | 22/595 | 269/18614 | 1e-04 | 7e-04 | 22 |
| GO:0061844 | antimicrobial humoral immune response mediated by antimicrobial peptide | 11/595 | 82/18614 | 1e-04 | 8e-04 | 11 |
| GO:0070661 | leukocyte proliferation | 26/595 | 348/18614 | 1e-04 | 8e-04 | 26 |
| GO:0022898 | regulation of transmembrane transporter activity | 23/595 | 289/18614 | 1e-04 | 8e-04 | 23 |
| GO:0009314 | response to radiation | 31/595 | 452/18614 | 1e-04 | 8e-04 | 31 |
| GO:0002253 | activation of immune response | 33/595 | 495/18614 | 1e-04 | 8e-04 | 33 |
| GO:0018105 | peptidyl-serine phosphorylation | 24/595 | 309/18614 | 1e-04 | 8e-04 | 24 |
| GO:0050671 | positive regulation of lymphocyte proliferation | 15/595 | 145/18614 | 1e-04 | 8e-04 | 15 |
| GO:0007187 | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | 9/595 | 56/18614 | 1e-04 | 8e-04 | 9 |
| GO:0050832 | defense response to fungus | 9/595 | 56/18614 | 1e-04 | 8e-04 | 9 |
| GO:0043549 | regulation of kinase activity | 43/595 | 720/18614 | 1e-04 | 8e-04 | 43 |
| GO:0072243 | metanephric nephron epithelium development | 6/595 | 23/18614 | 1e-04 | 8e-04 | 6 |
| GO:0001816 | cytokine production | 49/595 | 860/18614 | 1e-04 | 8e-04 | 49 |
| GO:0032642 | regulation of chemokine production | 12/595 | 98/18614 | 1e-04 | 9e-04 | 12 |
| GO:0035265 | organ growth | 17/595 | 180/18614 | 1e-04 | 9e-04 | 17 |
| GO:0050714 | positive regulation of protein secretion | 15/595 | 146/18614 | 1e-04 | 9e-04 | 15 |
| GO:0060326 | cell chemotaxis | 24/595 | 312/18614 | 1e-04 | 9e-04 | 24 |
| GO:0050727 | regulation of inflammatory response | 29/595 | 414/18614 | 1e-04 | 9e-04 | 29 |
| GO:0007266 | Rho protein signal transduction | 14/595 | 130/18614 | 1e-04 | 9e-04 | 14 |
| GO:0032943 | mononuclear cell proliferation | 24/595 | 313/18614 | 1e-04 | 9e-04 | 24 |
| GO:0032602 | chemokine production | 12/595 | 99/18614 | 1e-04 | 9e-04 | 12 |
| GO:0006909 | phagocytosis | 20/595 | 236/18614 | 1e-04 | 9e-04 | 20 |
| GO:0002687 | positive regulation of leukocyte migration | 15/595 | 147/18614 | 1e-04 | 9e-04 | 15 |
| GO:0034116 | positive regulation of heterotypic cell-cell adhesion | 5/595 | 15/18614 | 1e-04 | 9e-04 | 5 |
| GO:0045989 | positive regulation of striated muscle contraction | 5/595 | 15/18614 | 1e-04 | 9e-04 | 5 |
| GO:0001504 | neurotransmitter uptake | 8/595 | 45/18614 | 1e-04 | 1e-03 | 8 |
| GO:0098815 | modulation of excitatory postsynaptic potential | 8/595 | 45/18614 | 1e-04 | 1e-03 | 8 |
| GO:0032946 | positive regulation of mononuclear cell proliferation | 15/595 | 148/18614 | 1e-04 | 1e-03 | 15 |
A2 (38 terms)
| ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
|---|---|---|---|---|---|---|
| GO:0045333 | cellular respiration | 25/364 | 243/18614 | 0 | 0e+00 | 25 |
| GO:0016071 | mRNA metabolic process | 45/364 | 769/18614 | 0 | 0e+00 | 45 |
| GO:0000375 | RNA splicing, via transesterification reactions | 28/364 | 329/18614 | 0 | 0e+00 | 28 |
| GO:0015980 | energy derivation by oxidation of organic compounds | 28/364 | 337/18614 | 0 | 0e+00 | 28 |
| GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 27/364 | 325/18614 | 0 | 0e+00 | 27 |
| GO:0000398 | mRNA splicing, via spliceosome | 27/364 | 325/18614 | 0 | 0e+00 | 27 |
| GO:0009060 | aerobic respiration | 21/364 | 196/18614 | 0 | 0e+00 | 21 |
| GO:0006119 | oxidative phosphorylation | 18/364 | 148/18614 | 0 | 0e+00 | 18 |
| GO:0008380 | RNA splicing | 32/364 | 466/18614 | 0 | 0e+00 | 32 |
| GO:0006397 | mRNA processing | 33/364 | 500/18614 | 0 | 0e+00 | 33 |
| GO:0022904 | respiratory electron transport chain | 16/364 | 124/18614 | 0 | 0e+00 | 16 |
| GO:0006886 | intracellular protein transport | 45/364 | 875/18614 | 0 | 0e+00 | 45 |
| GO:0019646 | aerobic electron transport chain | 14/364 | 94/18614 | 0 | 0e+00 | 14 |
| GO:0042773 | ATP synthesis coupled electron transport | 14/364 | 102/18614 | 0 | 0e+00 | 14 |
| GO:0042775 | mitochondrial ATP synthesis coupled electron transport | 14/364 | 102/18614 | 0 | 0e+00 | 14 |
| GO:0048024 | regulation of mRNA splicing, via spliceosome | 14/364 | 108/18614 | 0 | 0e+00 | 14 |
| GO:0022900 | electron transport chain | 17/364 | 177/18614 | 0 | 0e+00 | 17 |
| GO:0050684 | regulation of mRNA processing | 15/364 | 139/18614 | 0 | 0e+00 | 15 |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 27/364 | 439/18614 | 0 | 0e+00 | 27 |
| GO:0010498 | proteasomal protein catabolic process | 29/364 | 508/18614 | 0 | 1e-04 | 29 |
| GO:0006091 | generation of precursor metabolites and energy | 29/364 | 510/18614 | 0 | 1e-04 | 29 |
| GO:0043632 | modification-dependent macromolecule catabolic process | 35/364 | 702/18614 | 0 | 1e-04 | 35 |
| GO:0006913 | nucleocytoplasmic transport | 22/364 | 328/18614 | 0 | 1e-04 | 22 |
| GO:0051169 | nuclear transport | 22/364 | 328/18614 | 0 | 1e-04 | 22 |
| GO:0006511 | ubiquitin-dependent protein catabolic process | 34/364 | 680/18614 | 0 | 1e-04 | 34 |
| GO:1903311 | regulation of mRNA metabolic process | 22/364 | 329/18614 | 0 | 1e-04 | 22 |
| GO:0043484 | regulation of RNA splicing | 16/364 | 182/18614 | 0 | 1e-04 | 16 |
| GO:0006518 | peptide metabolic process | 42/364 | 954/18614 | 0 | 1e-04 | 42 |
| GO:0022613 | ribonucleoprotein complex biogenesis | 27/364 | 475/18614 | 0 | 1e-04 | 27 |
| GO:0019941 | modification-dependent protein catabolic process | 34/364 | 690/18614 | 0 | 1e-04 | 34 |
| GO:1902600 | proton transmembrane transport | 14/364 | 143/18614 | 0 | 1e-04 | 14 |
| GO:0051603 | proteolysis involved in protein catabolic process | 36/364 | 785/18614 | 0 | 3e-04 | 36 |
| GO:0006974 | cellular response to DNA damage stimulus | 38/364 | 871/18614 | 0 | 4e-04 | 38 |
| GO:0043043 | peptide biosynthetic process | 36/364 | 820/18614 | 0 | 6e-04 | 36 |
| GO:0006413 | translational initiation | 12/364 | 123/18614 | 0 | 6e-04 | 12 |
| GO:0006412 | translation | 35/364 | 790/18614 | 0 | 7e-04 | 35 |
| GO:0006457 | protein folding | 16/364 | 220/18614 | 0 | 8e-04 | 16 |
| GO:0006403 | RNA localization | 15/364 | 197/18614 | 0 | 9e-04 | 15 |
B1 (94 terms)
| ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
|---|---|---|---|---|---|---|
| GO:0033993 | response to lipid | 36/165 | 921/18614 | 0 | 0e+00 | 36 |
| GO:0034097 | response to cytokine | 34/165 | 933/18614 | 0 | 0e+00 | 34 |
| GO:0009617 | response to bacterium | 29/165 | 725/18614 | 0 | 0e+00 | 29 |
| GO:0002252 | immune effector process | 27/165 | 637/18614 | 0 | 0e+00 | 27 |
| GO:0006954 | inflammatory response | 31/165 | 852/18614 | 0 | 0e+00 | 31 |
| GO:0030155 | regulation of cell adhesion | 30/165 | 803/18614 | 0 | 0e+00 | 30 |
| GO:0045321 | leukocyte activation | 32/165 | 948/18614 | 0 | 0e+00 | 32 |
| GO:0019221 | cytokine-mediated signaling pathway | 23/165 | 492/18614 | 0 | 0e+00 | 23 |
| GO:0002237 | response to molecule of bacterial origin | 20/165 | 366/18614 | 0 | 0e+00 | 20 |
| GO:0071345 | cellular response to cytokine stimulus | 29/165 | 834/18614 | 0 | 0e+00 | 29 |
| GO:0050766 | positive regulation of phagocytosis | 10/165 | 73/18614 | 0 | 0e+00 | 10 |
| GO:0050764 | regulation of phagocytosis | 11/165 | 101/18614 | 0 | 0e+00 | 11 |
| GO:0032496 | response to lipopolysaccharide | 18/165 | 345/18614 | 0 | 0e+00 | 18 |
| GO:0060627 | regulation of vesicle-mediated transport | 22/165 | 530/18614 | 0 | 0e+00 | 22 |
| GO:0002274 | myeloid leukocyte activation | 15/165 | 240/18614 | 0 | 0e+00 | 15 |
| GO:0006959 | humoral immune response | 15/165 | 250/18614 | 0 | 0e+00 | 15 |
| GO:0050865 | regulation of cell activation | 23/165 | 655/18614 | 0 | 0e+00 | 23 |
| GO:0042110 | T cell activation | 21/165 | 554/18614 | 0 | 0e+00 | 21 |
| GO:0030595 | leukocyte chemotaxis | 14/165 | 241/18614 | 0 | 0e+00 | 14 |
| GO:0009611 | response to wounding | 21/165 | 575/18614 | 0 | 0e+00 | 21 |
| GO:0002366 | leukocyte activation involved in immune response | 15/165 | 296/18614 | 0 | 0e+00 | 15 |
| GO:0002263 | cell activation involved in immune response | 15/165 | 300/18614 | 0 | 0e+00 | 15 |
| GO:0050900 | leukocyte migration | 17/165 | 393/18614 | 0 | 0e+00 | 17 |
| GO:0002443 | leukocyte mediated immunity | 17/165 | 401/18614 | 0 | 0e+00 | 17 |
| GO:0060326 | cell chemotaxis | 15/165 | 312/18614 | 0 | 0e+00 | 15 |
| GO:0051050 | positive regulation of transport | 26/165 | 913/18614 | 0 | 0e+00 | 26 |
| GO:0045087 | innate immune response | 26/165 | 916/18614 | 0 | 0e+00 | 26 |
| GO:1901652 | response to peptide | 19/165 | 514/18614 | 0 | 0e+00 | 19 |
| GO:0006909 | phagocytosis | 13/165 | 236/18614 | 0 | 0e+00 | 13 |
| GO:0071219 | cellular response to molecule of bacterial origin | 13/165 | 237/18614 | 0 | 0e+00 | 13 |
| GO:0097529 | myeloid leukocyte migration | 13/165 | 241/18614 | 0 | 0e+00 | 13 |
| GO:0045785 | positive regulation of cell adhesion | 18/165 | 482/18614 | 0 | 0e+00 | 18 |
| GO:0042060 | wound healing | 17/165 | 439/18614 | 0 | 0e+00 | 17 |
| GO:0003013 | circulatory system process | 20/165 | 602/18614 | 0 | 0e+00 | 20 |
| GO:0071396 | cellular response to lipid | 20/165 | 608/18614 | 0 | 0e+00 | 20 |
| GO:0006935 | chemotaxis | 20/165 | 614/18614 | 0 | 1e-04 | 20 |
| GO:0042330 | taxis | 20/165 | 616/18614 | 0 | 1e-04 | 20 |
| GO:0002444 | myeloid leukocyte mediated immunity | 9/165 | 110/18614 | 0 | 1e-04 | 9 |
| GO:0071216 | cellular response to biotic stimulus | 13/165 | 264/18614 | 0 | 1e-04 | 13 |
| GO:0014070 | response to organic cyclic compound | 25/165 | 932/18614 | 0 | 1e-04 | 25 |
| GO:0071222 | cellular response to lipopolysaccharide | 12/165 | 224/18614 | 0 | 1e-04 | 12 |
| GO:0098609 | cell-cell adhesion | 25/165 | 950/18614 | 0 | 1e-04 | 25 |
| GO:0002694 | regulation of leukocyte activation | 19/165 | 598/18614 | 0 | 1e-04 | 19 |
| GO:0046649 | lymphocyte activation | 22/165 | 782/18614 | 0 | 1e-04 | 22 |
| GO:0002697 | regulation of immune effector process | 15/165 | 384/18614 | 0 | 1e-04 | 15 |
| GO:0051336 | regulation of hydrolase activity | 25/165 | 979/18614 | 0 | 1e-04 | 25 |
| GO:0022407 | regulation of cell-cell adhesion | 17/165 | 491/18614 | 0 | 1e-04 | 17 |
| GO:0071674 | mononuclear cell migration | 11/165 | 202/18614 | 0 | 1e-04 | 11 |
| GO:0071417 | cellular response to organonitrogen compound | 20/165 | 669/18614 | 0 | 1e-04 | 20 |
| GO:0050776 | regulation of immune response | 23/165 | 863/18614 | 0 | 2e-04 | 23 |
| GO:0045576 | mast cell activation | 7/165 | 69/18614 | 0 | 2e-04 | 7 |
| GO:0007568 | aging | 10/165 | 169/18614 | 0 | 2e-04 | 10 |
| GO:0062197 | cellular response to chemical stress | 14/165 | 349/18614 | 0 | 2e-04 | 14 |
| GO:0010035 | response to inorganic substance | 18/165 | 567/18614 | 0 | 2e-04 | 18 |
| GO:0097435 | supramolecular fiber organization | 22/165 | 812/18614 | 0 | 2e-04 | 22 |
| GO:0002455 | humoral immune response mediated by circulating immunoglobulin | 6/165 | 46/18614 | 0 | 2e-04 | 6 |
| GO:0008015 | blood circulation | 17/165 | 516/18614 | 0 | 2e-04 | 17 |
| GO:0043300 | regulation of leukocyte degranulation | 6/165 | 48/18614 | 0 | 2e-04 | 6 |
| GO:0034341 | response to type II interferon | 9/165 | 139/18614 | 0 | 2e-04 | 9 |
| GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 13/165 | 311/18614 | 0 | 2e-04 | 13 |
| GO:0050878 | regulation of body fluid levels | 14/165 | 361/18614 | 0 | 2e-04 | 14 |
| GO:0030198 | extracellular matrix organization | 13/165 | 314/18614 | 0 | 3e-04 | 13 |
| GO:1901699 | cellular response to nitrogen compound | 20/165 | 707/18614 | 0 | 3e-04 | 20 |
| GO:0043062 | extracellular structure organization | 13/165 | 315/18614 | 0 | 3e-04 | 13 |
| GO:0045229 | external encapsulating structure organization | 13/165 | 317/18614 | 0 | 3e-04 | 13 |
| GO:0050866 | negative regulation of cell activation | 11/165 | 225/18614 | 0 | 3e-04 | 11 |
| GO:0010543 | regulation of platelet activation | 6/165 | 52/18614 | 0 | 3e-04 | 6 |
| GO:0008217 | regulation of blood pressure | 10/165 | 187/18614 | 0 | 3e-04 | 10 |
| GO:0030162 | regulation of proteolysis | 20/165 | 727/18614 | 0 | 4e-04 | 20 |
| GO:0043304 | regulation of mast cell degranulation | 5/165 | 31/18614 | 0 | 4e-04 | 5 |
| GO:0043299 | leukocyte degranulation | 7/165 | 81/18614 | 0 | 4e-04 | 7 |
| GO:0071706 | tumor necrosis factor superfamily cytokine production | 10/165 | 190/18614 | 0 | 4e-04 | 10 |
| GO:1903555 | regulation of tumor necrosis factor superfamily cytokine production | 10/165 | 190/18614 | 0 | 4e-04 | 10 |
| GO:0030097 | hemopoiesis | 23/165 | 930/18614 | 0 | 4e-04 | 23 |
| GO:0043303 | mast cell degranulation | 6/165 | 54/18614 | 0 | 4e-04 | 6 |
| GO:0070482 | response to oxygen levels | 13/165 | 333/18614 | 0 | 4e-04 | 13 |
| GO:0071346 | cellular response to type II interferon | 8/165 | 116/18614 | 0 | 4e-04 | 8 |
| GO:0002279 | mast cell activation involved in immune response | 6/165 | 56/18614 | 0 | 4e-04 | 6 |
| GO:0033006 | regulation of mast cell activation involved in immune response | 5/165 | 33/18614 | 0 | 4e-04 | 5 |
| GO:0009725 | response to hormone | 22/165 | 880/18614 | 0 | 5e-04 | 22 |
| GO:0002448 | mast cell mediated immunity | 6/165 | 57/18614 | 0 | 5e-04 | 6 |
| GO:0001666 | response to hypoxia | 12/165 | 293/18614 | 0 | 5e-04 | 12 |
| GO:0002886 | regulation of myeloid leukocyte mediated immunity | 6/165 | 60/18614 | 0 | 6e-04 | 6 |
| GO:0070098 | chemokine-mediated signaling pathway | 7/165 | 91/18614 | 0 | 7e-04 | 7 |
| GO:0019730 | antimicrobial humoral response | 8/165 | 126/18614 | 0 | 7e-04 | 8 |
| GO:0036293 | response to decreased oxygen levels | 12/165 | 306/18614 | 0 | 8e-04 | 12 |
| GO:0001817 | regulation of cytokine production | 21/165 | 847/18614 | 0 | 8e-04 | 21 |
| GO:0003073 | regulation of systemic arterial blood pressure | 7/165 | 94/18614 | 0 | 8e-04 | 7 |
| GO:0007162 | negative regulation of cell adhesion | 12/165 | 312/18614 | 0 | 9e-04 | 12 |
| GO:0000165 | MAPK cascade | 20/165 | 791/18614 | 0 | 9e-04 | 20 |
| GO:0007259 | receptor signaling pathway via JAK-STAT | 9/165 | 173/18614 | 0 | 9e-04 | 9 |
| GO:0001816 | cytokine production | 21/165 | 860/18614 | 0 | 9e-04 | 21 |
| GO:0052547 | regulation of peptidase activity | 14/165 | 425/18614 | 0 | 1e-03 | 14 |
| GO:0002275 | myeloid cell activation involved in immune response | 7/165 | 98/18614 | 0 | 1e-03 | 7 |
B2 (162 terms)
| ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
|---|---|---|---|---|---|---|
| GO:0006974 | cellular response to DNA damage stimulus | 66/374 | 871/18614 | 0 | 0e+00 | 66 |
| GO:0051276 | chromosome organization | 55/374 | 626/18614 | 0 | 0e+00 | 55 |
| GO:0006281 | DNA repair | 49/374 | 587/18614 | 0 | 0e+00 | 49 |
| GO:0051052 | regulation of DNA metabolic process | 46/374 | 537/18614 | 0 | 0e+00 | 46 |
| GO:0000278 | mitotic cell cycle | 61/374 | 933/18614 | 0 | 0e+00 | 61 |
| GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 35/374 | 325/18614 | 0 | 0e+00 | 35 |
| GO:0000398 | mRNA splicing, via spliceosome | 35/374 | 325/18614 | 0 | 0e+00 | 35 |
| GO:0000375 | RNA splicing, via transesterification reactions | 35/374 | 329/18614 | 0 | 0e+00 | 35 |
| GO:1903047 | mitotic cell cycle process | 54/374 | 777/18614 | 0 | 0e+00 | 54 |
| GO:0006325 | chromatin organization | 49/374 | 653/18614 | 0 | 0e+00 | 49 |
| GO:0033044 | regulation of chromosome organization | 30/374 | 250/18614 | 0 | 0e+00 | 30 |
| GO:0050684 | regulation of mRNA processing | 23/374 | 139/18614 | 0 | 0e+00 | 23 |
| GO:0006260 | DNA replication | 31/374 | 278/18614 | 0 | 0e+00 | 31 |
| GO:0006403 | RNA localization | 26/374 | 197/18614 | 0 | 0e+00 | 26 |
| GO:0008380 | RNA splicing | 38/374 | 466/18614 | 0 | 0e+00 | 38 |
| GO:0071897 | DNA biosynthetic process | 25/374 | 198/18614 | 0 | 0e+00 | 25 |
| GO:0006397 | mRNA processing | 39/374 | 500/18614 | 0 | 0e+00 | 39 |
| GO:2001252 | positive regulation of chromosome organization | 19/374 | 111/18614 | 0 | 0e+00 | 19 |
| GO:0034502 | protein localization to chromosome | 19/374 | 116/18614 | 0 | 0e+00 | 19 |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | 55/374 | 961/18614 | 0 | 0e+00 | 55 |
| GO:0016071 | mRNA metabolic process | 48/374 | 769/18614 | 0 | 0e+00 | 48 |
| GO:0051054 | positive regulation of DNA metabolic process | 29/374 | 303/18614 | 0 | 0e+00 | 29 |
| GO:2000278 | regulation of DNA biosynthetic process | 19/374 | 121/18614 | 0 | 0e+00 | 19 |
| GO:0048024 | regulation of mRNA splicing, via spliceosome | 18/374 | 108/18614 | 0 | 0e+00 | 18 |
| GO:1903311 | regulation of mRNA metabolic process | 30/374 | 329/18614 | 0 | 0e+00 | 30 |
| GO:0006310 | DNA recombination | 30/374 | 332/18614 | 0 | 0e+00 | 30 |
| GO:0070198 | protein localization to chromosome, telomeric region | 11/374 | 30/18614 | 0 | 0e+00 | 11 |
| GO:0006261 | DNA-templated DNA replication | 21/374 | 160/18614 | 0 | 0e+00 | 21 |
| GO:1904356 | regulation of telomere maintenance via telomere lengthening | 14/374 | 61/18614 | 0 | 0e+00 | 14 |
| GO:2000573 | positive regulation of DNA biosynthetic process | 15/374 | 74/18614 | 0 | 0e+00 | 15 |
| GO:0033365 | protein localization to organelle | 52/374 | 932/18614 | 0 | 0e+00 | 52 |
| GO:0006338 | chromatin remodeling | 32/374 | 402/18614 | 0 | 0e+00 | 32 |
| GO:0000723 | telomere maintenance | 20/374 | 156/18614 | 0 | 0e+00 | 20 |
| GO:0010833 | telomere maintenance via telomere lengthening | 15/374 | 81/18614 | 0 | 0e+00 | 15 |
| GO:0007346 | regulation of mitotic cell cycle | 36/374 | 517/18614 | 0 | 0e+00 | 36 |
| GO:1904358 | positive regulation of telomere maintenance via telomere lengthening | 11/374 | 37/18614 | 0 | 0e+00 | 11 |
| GO:0043484 | regulation of RNA splicing | 21/374 | 182/18614 | 0 | 0e+00 | 21 |
| GO:1904851 | positive regulation of establishment of protein localization to telomere | 7/374 | 10/18614 | 0 | 0e+00 | 7 |
| GO:0010564 | regulation of cell cycle process | 44/374 | 747/18614 | 0 | 0e+00 | 44 |
| GO:0032200 | telomere organization | 21/374 | 187/18614 | 0 | 0e+00 | 21 |
| GO:0040029 | epigenetic regulation of gene expression | 21/374 | 188/18614 | 0 | 0e+00 | 21 |
| GO:0006278 | RNA-templated DNA biosynthetic process | 14/374 | 75/18614 | 0 | 0e+00 | 14 |
| GO:0032204 | regulation of telomere maintenance | 16/374 | 104/18614 | 0 | 0e+00 | 16 |
| GO:0022618 | ribonucleoprotein complex assembly | 23/374 | 231/18614 | 0 | 0e+00 | 23 |
| GO:0071103 | DNA conformation change | 15/374 | 90/18614 | 0 | 0e+00 | 15 |
| GO:0070203 | regulation of establishment of protein localization to telomere | 7/374 | 11/18614 | 0 | 0e+00 | 7 |
| GO:1904869 | regulation of protein localization to Cajal body | 7/374 | 11/18614 | 0 | 0e+00 | 7 |
| GO:1904871 | positive regulation of protein localization to Cajal body | 7/374 | 11/18614 | 0 | 0e+00 | 7 |
| GO:0044770 | cell cycle phase transition | 37/374 | 571/18614 | 0 | 0e+00 | 37 |
| GO:0044772 | mitotic cell cycle phase transition | 33/374 | 467/18614 | 0 | 0e+00 | 33 |
| GO:0032210 | regulation of telomere maintenance via telomerase | 12/374 | 53/18614 | 0 | 0e+00 | 12 |
| GO:0071826 | ribonucleoprotein complex subunit organization | 23/374 | 239/18614 | 0 | 0e+00 | 23 |
| GO:0032212 | positive regulation of telomere maintenance via telomerase | 10/374 | 34/18614 | 0 | 0e+00 | 10 |
| GO:0070202 | regulation of establishment of protein localization to chromosome | 7/374 | 12/18614 | 0 | 0e+00 | 7 |
| GO:1903405 | protein localization to nuclear body | 7/374 | 12/18614 | 0 | 0e+00 | 7 |
| GO:1904816 | positive regulation of protein localization to chromosome, telomeric region | 7/374 | 12/18614 | 0 | 0e+00 | 7 |
| GO:1904867 | protein localization to Cajal body | 7/374 | 12/18614 | 0 | 0e+00 | 7 |
| GO:0007004 | telomere maintenance via telomerase | 13/374 | 69/18614 | 0 | 0e+00 | 13 |
| GO:0032392 | DNA geometric change | 14/374 | 83/18614 | 0 | 0e+00 | 14 |
| GO:0032206 | positive regulation of telomere maintenance | 13/374 | 70/18614 | 0 | 0e+00 | 13 |
| GO:0070828 | heterochromatin organization | 15/374 | 105/18614 | 0 | 0e+00 | 15 |
| GO:1901987 | regulation of cell cycle phase transition | 31/374 | 457/18614 | 0 | 0e+00 | 31 |
| GO:1904814 | regulation of protein localization to chromosome, telomeric region | 7/374 | 14/18614 | 0 | 0e+00 | 7 |
| GO:1990173 | protein localization to nucleoplasm | 7/374 | 14/18614 | 0 | 0e+00 | 7 |
| GO:1901990 | regulation of mitotic cell cycle phase transition | 27/374 | 357/18614 | 0 | 0e+00 | 27 |
| GO:0002521 | leukocyte differentiation | 36/374 | 605/18614 | 0 | 0e+00 | 36 |
| GO:1904874 | positive regulation of telomerase RNA localization to Cajal body | 7/374 | 15/18614 | 0 | 0e+00 | 7 |
| GO:0031507 | heterochromatin formation | 14/374 | 96/18614 | 0 | 0e+00 | 14 |
| GO:0006275 | regulation of DNA replication | 16/374 | 136/18614 | 0 | 0e+00 | 16 |
| GO:0070200 | establishment of protein localization to telomere | 7/374 | 17/18614 | 0 | 0e+00 | 7 |
| GO:0010948 | negative regulation of cell cycle process | 24/374 | 317/18614 | 0 | 0e+00 | 24 |
| GO:0051236 | establishment of RNA localization | 17/374 | 163/18614 | 0 | 0e+00 | 17 |
| GO:1904872 | regulation of telomerase RNA localization to Cajal body | 7/374 | 18/18614 | 0 | 0e+00 | 7 |
| GO:0006270 | DNA replication initiation | 9/374 | 37/18614 | 0 | 0e+00 | 9 |
| GO:0045814 | negative regulation of gene expression, epigenetic | 14/374 | 109/18614 | 0 | 0e+00 | 14 |
| GO:0033260 | nuclear DNA replication | 9/374 | 38/18614 | 0 | 0e+00 | 9 |
| GO:0000245 | spliceosomal complex assembly | 13/374 | 94/18614 | 0 | 0e+00 | 13 |
| GO:0090670 | RNA localization to Cajal body | 7/374 | 19/18614 | 0 | 0e+00 | 7 |
| GO:0090671 | telomerase RNA localization to Cajal body | 7/374 | 19/18614 | 0 | 0e+00 | 7 |
| GO:0090672 | telomerase RNA localization | 7/374 | 19/18614 | 0 | 0e+00 | 7 |
| GO:0090685 | RNA localization to nucleus | 7/374 | 19/18614 | 0 | 0e+00 | 7 |
| GO:0006302 | double-strand break repair | 23/374 | 303/18614 | 0 | 0e+00 | 23 |
| GO:0022613 | ribonucleoprotein complex biogenesis | 29/374 | 475/18614 | 0 | 0e+00 | 29 |
| GO:0044786 | cell cycle DNA replication | 9/374 | 43/18614 | 0 | 0e+00 | 9 |
| GO:0010638 | positive regulation of organelle organization | 30/374 | 508/18614 | 0 | 0e+00 | 30 |
| GO:0050657 | nucleic acid transport | 16/374 | 160/18614 | 0 | 0e+00 | 16 |
| GO:0050658 | RNA transport | 16/374 | 160/18614 | 0 | 0e+00 | 16 |
| GO:0072594 | establishment of protein localization to organelle | 28/374 | 453/18614 | 0 | 0e+00 | 28 |
| GO:0000380 | alternative mRNA splicing, via spliceosome | 11/374 | 72/18614 | 0 | 0e+00 | 11 |
| GO:0000082 | G1/S transition of mitotic cell cycle | 20/374 | 251/18614 | 0 | 0e+00 | 20 |
| GO:0090329 | regulation of DNA-templated DNA replication | 10/374 | 58/18614 | 0 | 0e+00 | 10 |
| GO:2000045 | regulation of G1/S transition of mitotic cell cycle | 17/374 | 186/18614 | 0 | 0e+00 | 17 |
| GO:0051301 | cell division | 34/374 | 636/18614 | 0 | 0e+00 | 34 |
| GO:0030097 | hemopoiesis | 43/374 | 930/18614 | 0 | 0e+00 | 43 |
| GO:0032508 | DNA duplex unwinding | 11/374 | 77/18614 | 0 | 0e+00 | 11 |
| GO:1901991 | negative regulation of mitotic cell cycle phase transition | 17/374 | 194/18614 | 0 | 0e+00 | 17 |
| GO:1901988 | negative regulation of cell cycle phase transition | 20/374 | 274/18614 | 0 | 0e+00 | 20 |
| GO:0042113 | B cell activation | 20/374 | 276/18614 | 0 | 0e+00 | 20 |
| GO:0070199 | establishment of protein localization to chromosome | 7/374 | 28/18614 | 0 | 0e+00 | 7 |
| GO:0044843 | cell cycle G1/S phase transition | 20/374 | 281/18614 | 0 | 0e+00 | 20 |
| GO:0010212 | response to ionizing radiation | 14/374 | 143/18614 | 0 | 0e+00 | 14 |
| GO:0000381 | regulation of alternative mRNA splicing, via spliceosome | 9/374 | 56/18614 | 0 | 1e-04 | 9 |
| GO:1902806 | regulation of cell cycle G1/S phase transition | 17/374 | 214/18614 | 0 | 1e-04 | 17 |
| GO:0071824 | protein-DNA complex subunit organization | 19/374 | 263/18614 | 0 | 1e-04 | 19 |
| GO:0010332 | response to gamma radiation | 9/374 | 57/18614 | 0 | 1e-04 | 9 |
| GO:0016032 | viral process | 25/374 | 426/18614 | 0 | 1e-04 | 25 |
| GO:0009394 | 2’-deoxyribonucleotide metabolic process | 8/374 | 43/18614 | 0 | 1e-04 | 8 |
| GO:0051095 | regulation of helicase activity | 5/374 | 12/18614 | 0 | 1e-04 | 5 |
| GO:0009262 | deoxyribonucleotide metabolic process | 8/374 | 44/18614 | 0 | 1e-04 | 8 |
| GO:0019692 | deoxyribose phosphate metabolic process | 8/374 | 44/18614 | 0 | 1e-04 | 8 |
| GO:0010720 | positive regulation of cell development | 25/374 | 432/18614 | 0 | 1e-04 | 25 |
| GO:0045786 | negative regulation of cell cycle | 24/374 | 404/18614 | 0 | 1e-04 | 24 |
| GO:0015931 | nucleobase-containing compound transport | 17/374 | 221/18614 | 0 | 1e-04 | 17 |
| GO:2001251 | negative regulation of chromosome organization | 11/374 | 93/18614 | 0 | 1e-04 | 11 |
| GO:0006352 | DNA-templated transcription initiation | 14/374 | 153/18614 | 0 | 1e-04 | 14 |
| GO:0046649 | lymphocyte activation | 36/374 | 782/18614 | 0 | 1e-04 | 36 |
| GO:0034504 | protein localization to nucleus | 20/374 | 304/18614 | 0 | 1e-04 | 20 |
| GO:2000736 | regulation of stem cell differentiation | 10/374 | 79/18614 | 0 | 1e-04 | 10 |
| GO:1903131 | mononuclear cell differentiation | 26/374 | 474/18614 | 0 | 1e-04 | 26 |
| GO:0006412 | translation | 36/374 | 790/18614 | 0 | 2e-04 | 36 |
| GO:0080135 | regulation of cellular response to stress | 34/374 | 726/18614 | 0 | 2e-04 | 34 |
| GO:0030099 | myeloid cell differentiation | 24/374 | 421/18614 | 0 | 2e-04 | 24 |
| GO:0030098 | lymphocyte differentiation | 24/374 | 422/18614 | 0 | 2e-04 | 24 |
| GO:2001020 | regulation of response to DNA damage stimulus | 20/374 | 311/18614 | 0 | 2e-04 | 20 |
| GO:0006304 | DNA modification | 12/374 | 120/18614 | 0 | 2e-04 | 12 |
| GO:1902969 | mitotic DNA replication | 5/374 | 14/18614 | 0 | 2e-04 | 5 |
| GO:1903241 | U2-type prespliceosome assembly | 6/374 | 24/18614 | 0 | 2e-04 | 6 |
| GO:0050821 | protein stabilization | 16/374 | 213/18614 | 0 | 2e-04 | 16 |
| GO:0006271 | DNA strand elongation involved in DNA replication | 5/374 | 15/18614 | 0 | 3e-04 | 5 |
| GO:0009263 | deoxyribonucleotide biosynthetic process | 5/374 | 15/18614 | 0 | 3e-04 | 5 |
| GO:0009265 | 2’-deoxyribonucleotide biosynthetic process | 5/374 | 15/18614 | 0 | 3e-04 | 5 |
| GO:0046385 | deoxyribose phosphate biosynthetic process | 5/374 | 15/18614 | 0 | 3e-04 | 5 |
| GO:0065004 | protein-DNA complex assembly | 17/374 | 242/18614 | 0 | 3e-04 | 17 |
| GO:0007059 | chromosome segregation | 24/374 | 435/18614 | 0 | 3e-04 | 24 |
| GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | 10/374 | 86/18614 | 0 | 3e-04 | 10 |
| GO:0045930 | negative regulation of mitotic cell cycle | 17/374 | 243/18614 | 0 | 3e-04 | 17 |
| GO:0061077 | chaperone-mediated protein folding | 9/374 | 69/18614 | 0 | 3e-04 | 9 |
| GO:0043043 | peptide biosynthetic process | 36/374 | 820/18614 | 0 | 3e-04 | 36 |
| GO:0044839 | cell cycle G2/M phase transition | 13/374 | 151/18614 | 0 | 4e-04 | 13 |
| GO:0097193 | intrinsic apoptotic signaling pathway | 19/374 | 301/18614 | 0 | 4e-04 | 19 |
| GO:0030162 | regulation of proteolysis | 33/374 | 727/18614 | 0 | 4e-04 | 33 |
| GO:0002562 | somatic diversification of immune receptors via germline recombination within a single locus | 9/374 | 71/18614 | 0 | 4e-04 | 9 |
| GO:0016444 | somatic cell DNA recombination | 9/374 | 71/18614 | 0 | 4e-04 | 9 |
| GO:0032922 | circadian regulation of gene expression | 9/374 | 71/18614 | 0 | 4e-04 | 9 |
| GO:0014070 | response to organic cyclic compound | 39/374 | 932/18614 | 0 | 4e-04 | 39 |
| GO:0016570 | histone modification | 25/374 | 475/18614 | 0 | 4e-04 | 25 |
| GO:0034097 | response to cytokine | 39/374 | 933/18614 | 0 | 4e-04 | 39 |
| GO:0048511 | rhythmic process | 19/374 | 303/18614 | 0 | 4e-04 | 19 |
| GO:1901998 | toxin transport | 7/374 | 40/18614 | 0 | 4e-04 | 7 |
| GO:1902749 | regulation of cell cycle G2/M phase transition | 11/374 | 112/18614 | 0 | 5e-04 | 11 |
| GO:0033151 | V(D)J recombination | 5/374 | 17/18614 | 0 | 5e-04 | 5 |
| GO:0034660 | ncRNA metabolic process | 29/374 | 611/18614 | 0 | 5e-04 | 29 |
| GO:0098727 | maintenance of cell number | 14/374 | 181/18614 | 0 | 5e-04 | 14 |
| GO:0007623 | circadian rhythm | 15/374 | 207/18614 | 0 | 6e-04 | 15 |
| GO:0007064 | mitotic sister chromatid cohesion | 6/374 | 30/18614 | 0 | 7e-04 | 6 |
| GO:1902807 | negative regulation of cell cycle G1/S phase transition | 10/374 | 97/18614 | 0 | 7e-04 | 10 |
| GO:0002200 | somatic diversification of immune receptors | 9/374 | 78/18614 | 0 | 7e-04 | 9 |
| GO:0043414 | macromolecule methylation | 19/374 | 320/18614 | 0 | 8e-04 | 19 |
| GO:0050792 | regulation of viral process | 13/374 | 165/18614 | 0 | 8e-04 | 13 |
| GO:0031647 | regulation of protein stability | 19/374 | 322/18614 | 0 | 8e-04 | 19 |
| GO:0071478 | cellular response to radiation | 14/374 | 191/18614 | 0 | 9e-04 | 14 |
| GO:0071345 | cellular response to cytokine stimulus | 35/374 | 834/18614 | 0 | 9e-04 | 35 |
C1 (3 terms)
| ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
|---|---|---|---|---|---|---|
| GO:0000278 | mitotic cell cycle | 26/136 | 933/18614 | 0 | 0e+00 | 26 |
| GO:1903047 | mitotic cell cycle process | 22/136 | 777/18614 | 0 | 1e-04 | 22 |
| GO:0044770 | cell cycle phase transition | 17/136 | 571/18614 | 0 | 9e-04 | 17 |
C2 (165 terms)
| ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
|---|---|---|---|---|---|---|
| GO:0002366 | leukocyte activation involved in immune response | 21/184 | 296/18614 | 0 | 0e+00 | 21 |
| GO:0002263 | cell activation involved in immune response | 21/184 | 300/18614 | 0 | 0e+00 | 21 |
| GO:0033993 | response to lipid | 35/184 | 921/18614 | 0 | 0e+00 | 35 |
| GO:0002252 | immune effector process | 29/184 | 637/18614 | 0 | 0e+00 | 29 |
| GO:0002697 | regulation of immune effector process | 22/184 | 384/18614 | 0 | 0e+00 | 22 |
| GO:0045321 | leukocyte activation | 33/184 | 948/18614 | 0 | 0e+00 | 33 |
| GO:0002700 | regulation of production of molecular mediator of immune response | 15/184 | 189/18614 | 0 | 0e+00 | 15 |
| GO:2001233 | regulation of apoptotic signaling pathway | 20/184 | 381/18614 | 0 | 0e+00 | 20 |
| GO:0050865 | regulation of cell activation | 26/184 | 655/18614 | 0 | 0e+00 | 26 |
| GO:0051050 | positive regulation of transport | 31/184 | 913/18614 | 0 | 0e+00 | 31 |
| GO:0032496 | response to lipopolysaccharide | 19/184 | 345/18614 | 0 | 0e+00 | 19 |
| GO:0002285 | lymphocyte activation involved in immune response | 15/184 | 208/18614 | 0 | 0e+00 | 15 |
| GO:0008284 | positive regulation of cell population proliferation | 32/184 | 986/18614 | 0 | 0e+00 | 32 |
| GO:0014070 | response to organic cyclic compound | 31/184 | 932/18614 | 0 | 0e+00 | 31 |
| GO:0019725 | cellular homeostasis | 28/184 | 789/18614 | 0 | 0e+00 | 28 |
| GO:0002237 | response to molecule of bacterial origin | 19/184 | 366/18614 | 0 | 0e+00 | 19 |
| GO:0001817 | regulation of cytokine production | 29/184 | 847/18614 | 0 | 0e+00 | 29 |
| GO:0006954 | inflammatory response | 29/184 | 852/18614 | 0 | 0e+00 | 29 |
| GO:0030155 | regulation of cell adhesion | 28/184 | 803/18614 | 0 | 0e+00 | 28 |
| GO:0001816 | cytokine production | 29/184 | 860/18614 | 0 | 0e+00 | 29 |
| GO:0097190 | apoptotic signaling pathway | 24/184 | 608/18614 | 0 | 0e+00 | 24 |
| GO:0045785 | positive regulation of cell adhesion | 21/184 | 482/18614 | 0 | 0e+00 | 21 |
| GO:0031589 | cell-substrate adhesion | 18/184 | 359/18614 | 0 | 0e+00 | 18 |
| GO:0055082 | intracellular chemical homeostasis | 25/184 | 689/18614 | 0 | 0e+00 | 25 |
| GO:0002694 | regulation of leukocyte activation | 23/184 | 598/18614 | 0 | 0e+00 | 23 |
| GO:0030003 | intracellular monoatomic cation homeostasis | 21/184 | 504/18614 | 0 | 0e+00 | 21 |
| GO:0001818 | negative regulation of cytokine production | 18/184 | 371/18614 | 0 | 0e+00 | 18 |
| GO:0006873 | intracellular monoatomic ion homeostasis | 21/184 | 513/18614 | 0 | 0e+00 | 21 |
| GO:0071222 | cellular response to lipopolysaccharide | 14/184 | 224/18614 | 0 | 0e+00 | 14 |
| GO:0046649 | lymphocyte activation | 26/184 | 782/18614 | 0 | 0e+00 | 26 |
| GO:0002637 | regulation of immunoglobulin production | 9/184 | 76/18614 | 0 | 0e+00 | 9 |
| GO:0062197 | cellular response to chemical stress | 17/184 | 349/18614 | 0 | 0e+00 | 17 |
| GO:0050867 | positive regulation of cell activation | 18/184 | 394/18614 | 0 | 0e+00 | 18 |
| GO:0071219 | cellular response to molecule of bacterial origin | 14/184 | 237/18614 | 0 | 0e+00 | 14 |
| GO:0048871 | multicellular organismal-level homeostasis | 25/184 | 759/18614 | 0 | 0e+00 | 25 |
| GO:0055080 | monoatomic cation homeostasis | 22/184 | 602/18614 | 0 | 0e+00 | 22 |
| GO:0034097 | response to cytokine | 28/184 | 933/18614 | 0 | 0e+00 | 28 |
| GO:0009725 | response to hormone | 27/184 | 880/18614 | 0 | 0e+00 | 27 |
| GO:0043069 | negative regulation of programmed cell death | 28/184 | 940/18614 | 0 | 0e+00 | 28 |
| GO:0002440 | production of molecular mediator of immune response | 16/184 | 328/18614 | 0 | 0e+00 | 16 |
| GO:0050801 | monoatomic ion homeostasis | 22/184 | 612/18614 | 0 | 0e+00 | 22 |
| GO:0006914 | autophagy | 21/184 | 565/18614 | 0 | 0e+00 | 21 |
| GO:0061919 | process utilizing autophagic mechanism | 21/184 | 565/18614 | 0 | 0e+00 | 21 |
| GO:0034599 | cellular response to oxidative stress | 15/184 | 290/18614 | 0 | 0e+00 | 15 |
| GO:0009617 | response to bacterium | 24/184 | 725/18614 | 0 | 0e+00 | 24 |
| GO:0010942 | positive regulation of cell death | 22/184 | 621/18614 | 0 | 0e+00 | 22 |
| GO:0002286 | T cell activation involved in immune response | 10/184 | 119/18614 | 0 | 0e+00 | 10 |
| GO:0043066 | negative regulation of apoptotic process | 27/184 | 913/18614 | 0 | 0e+00 | 27 |
| GO:0070661 | leukocyte proliferation | 16/184 | 348/18614 | 0 | 0e+00 | 16 |
| GO:0071216 | cellular response to biotic stimulus | 14/184 | 264/18614 | 0 | 0e+00 | 14 |
| GO:0050776 | regulation of immune response | 26/184 | 863/18614 | 0 | 0e+00 | 26 |
| GO:2000379 | positive regulation of reactive oxygen species metabolic process | 8/184 | 70/18614 | 0 | 0e+00 | 8 |
| GO:0002699 | positive regulation of immune effector process | 14/184 | 267/18614 | 0 | 0e+00 | 14 |
| GO:0070663 | regulation of leukocyte proliferation | 14/184 | 268/18614 | 0 | 0e+00 | 14 |
| GO:0042110 | T cell activation | 20/184 | 554/18614 | 0 | 0e+00 | 20 |
| GO:0071396 | cellular response to lipid | 21/184 | 608/18614 | 0 | 0e+00 | 21 |
| GO:0097067 | cellular response to thyroid hormone stimulus | 5/184 | 18/18614 | 0 | 0e+00 | 5 |
| GO:0007035 | vacuolar acidification | 6/184 | 33/18614 | 0 | 0e+00 | 6 |
| GO:0006935 | chemotaxis | 21/184 | 614/18614 | 0 | 1e-04 | 21 |
| GO:0042330 | taxis | 21/184 | 616/18614 | 0 | 1e-04 | 21 |
| GO:0007159 | leukocyte cell-cell adhesion | 17/184 | 415/18614 | 0 | 1e-04 | 17 |
| GO:0090322 | regulation of superoxide metabolic process | 6/184 | 34/18614 | 0 | 1e-04 | 6 |
| GO:0032930 | positive regulation of superoxide anion generation | 5/184 | 19/18614 | 0 | 1e-04 | 5 |
| GO:0030335 | positive regulation of cell migration | 20/184 | 569/18614 | 0 | 1e-04 | 20 |
| GO:0002696 | positive regulation of leukocyte activation | 16/184 | 377/18614 | 0 | 1e-04 | 16 |
| GO:0052547 | regulation of peptidase activity | 17/184 | 425/18614 | 0 | 1e-04 | 17 |
| GO:0051336 | regulation of hydrolase activity | 27/184 | 979/18614 | 0 | 1e-04 | 27 |
| GO:0043299 | leukocyte degranulation | 8/184 | 81/18614 | 0 | 1e-04 | 8 |
| GO:0006163 | purine nucleotide metabolic process | 19/184 | 535/18614 | 0 | 1e-04 | 19 |
| GO:0030097 | hemopoiesis | 26/184 | 930/18614 | 0 | 1e-04 | 26 |
| GO:2000147 | positive regulation of cell motility | 20/184 | 594/18614 | 0 | 1e-04 | 20 |
| GO:0010506 | regulation of autophagy | 15/184 | 348/18614 | 0 | 1e-04 | 15 |
| GO:0032928 | regulation of superoxide anion generation | 5/184 | 22/18614 | 0 | 1e-04 | 5 |
| GO:0098609 | cell-cell adhesion | 26/184 | 950/18614 | 0 | 1e-04 | 26 |
| GO:2000377 | regulation of reactive oxygen species metabolic process | 10/184 | 150/18614 | 0 | 1e-04 | 10 |
| GO:0002443 | leukocyte mediated immunity | 16/184 | 401/18614 | 0 | 1e-04 | 16 |
| GO:0071345 | cellular response to cytokine stimulus | 24/184 | 834/18614 | 0 | 1e-04 | 24 |
| GO:0051249 | regulation of lymphocyte activation | 18/184 | 503/18614 | 0 | 1e-04 | 18 |
| GO:0040017 | positive regulation of locomotion | 20/184 | 609/18614 | 0 | 1e-04 | 20 |
| GO:0032870 | cellular response to hormone stimulus | 20/184 | 611/18614 | 0 | 1e-04 | 20 |
| GO:0045628 | regulation of T-helper 2 cell differentiation | 4/184 | 11/18614 | 0 | 1e-04 | 4 |
| GO:0050878 | regulation of body fluid levels | 15/184 | 361/18614 | 0 | 1e-04 | 15 |
| GO:0007599 | hemostasis | 12/184 | 230/18614 | 0 | 1e-04 | 12 |
| GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 13/184 | 273/18614 | 0 | 2e-04 | 13 |
| GO:0072521 | purine-containing compound metabolic process | 19/184 | 565/18614 | 0 | 2e-04 | 19 |
| GO:0007584 | response to nutrient | 10/184 | 156/18614 | 0 | 2e-04 | 10 |
| GO:2001234 | negative regulation of apoptotic signaling pathway | 12/184 | 233/18614 | 0 | 2e-04 | 12 |
| GO:0010038 | response to metal ion | 15/184 | 367/18614 | 0 | 2e-04 | 15 |
| GO:0043302 | positive regulation of leukocyte degranulation | 5/184 | 25/18614 | 0 | 2e-04 | 5 |
| GO:0006909 | phagocytosis | 12/184 | 236/18614 | 0 | 2e-04 | 12 |
| GO:0072593 | reactive oxygen species metabolic process | 12/184 | 237/18614 | 0 | 2e-04 | 12 |
| GO:0010631 | epithelial cell migration | 15/184 | 371/18614 | 0 | 2e-04 | 15 |
| GO:0007160 | cell-matrix adhesion | 12/184 | 239/18614 | 0 | 2e-04 | 12 |
| GO:0090132 | epithelium migration | 15/184 | 374/18614 | 0 | 2e-04 | 15 |
| GO:0002274 | myeloid leukocyte activation | 12/184 | 240/18614 | 0 | 2e-04 | 12 |
| GO:1903307 | positive regulation of regulated secretory pathway | 6/184 | 45/18614 | 0 | 2e-04 | 6 |
| GO:0090130 | tissue migration | 15/184 | 379/18614 | 0 | 2e-04 | 15 |
| GO:0034394 | protein localization to cell surface | 7/184 | 70/18614 | 0 | 2e-04 | 7 |
| GO:0048661 | positive regulation of smooth muscle cell proliferation | 8/184 | 99/18614 | 0 | 2e-04 | 8 |
| GO:0002703 | regulation of leukocyte mediated immunity | 12/184 | 246/18614 | 0 | 2e-04 | 12 |
| GO:0043065 | positive regulation of apoptotic process | 18/184 | 536/18614 | 0 | 2e-04 | 18 |
| GO:0006979 | response to oxidative stress | 16/184 | 434/18614 | 0 | 3e-04 | 16 |
| GO:0009117 | nucleotide metabolic process | 19/184 | 593/18614 | 0 | 3e-04 | 19 |
| GO:0033002 | muscle cell proliferation | 12/184 | 249/18614 | 0 | 3e-04 | 12 |
| GO:0007249 | I-kappaB kinase/NF-kappaB signaling | 13/184 | 293/18614 | 0 | 3e-04 | 13 |
| GO:0036230 | granulocyte activation | 6/184 | 48/18614 | 0 | 3e-04 | 6 |
| GO:0043300 | regulation of leukocyte degranulation | 6/184 | 48/18614 | 0 | 3e-04 | 6 |
| GO:0098771 | inorganic ion homeostasis | 18/184 | 542/18614 | 0 | 3e-04 | 18 |
| GO:1905477 | positive regulation of protein localization to membrane | 8/184 | 102/18614 | 0 | 3e-04 | 8 |
| GO:0048732 | gland development | 16/184 | 441/18614 | 0 | 3e-04 | 16 |
| GO:0006753 | nucleoside phosphate metabolic process | 19/184 | 601/18614 | 0 | 3e-04 | 19 |
| GO:0050900 | leukocyte migration | 15/184 | 393/18614 | 0 | 3e-04 | 15 |
| GO:0006898 | receptor-mediated endocytosis | 12/184 | 256/18614 | 0 | 3e-04 | 12 |
| GO:0097193 | intrinsic apoptotic signaling pathway | 13/184 | 301/18614 | 0 | 3e-04 | 13 |
| GO:0043068 | positive regulation of programmed cell death | 18/184 | 553/18614 | 0 | 3e-04 | 18 |
| GO:0097066 | response to thyroid hormone | 5/184 | 30/18614 | 0 | 3e-04 | 5 |
| GO:0060341 | regulation of cellular localization | 25/184 | 969/18614 | 0 | 3e-04 | 25 |
| GO:0061082 | myeloid leukocyte cytokine production | 6/184 | 51/18614 | 0 | 3e-04 | 6 |
| GO:0031400 | negative regulation of protein modification process | 17/184 | 503/18614 | 0 | 3e-04 | 17 |
| GO:0030162 | regulation of proteolysis | 21/184 | 727/18614 | 0 | 3e-04 | 21 |
| GO:0040007 | growth | 24/184 | 919/18614 | 0 | 4e-04 | 24 |
| GO:0045921 | positive regulation of exocytosis | 7/184 | 80/18614 | 0 | 4e-04 | 7 |
| GO:0007596 | blood coagulation | 11/184 | 224/18614 | 0 | 5e-04 | 11 |
| GO:0051452 | intracellular pH reduction | 6/184 | 54/18614 | 0 | 5e-04 | 6 |
| GO:0097191 | extrinsic apoptotic signaling pathway | 11/184 | 227/18614 | 0 | 5e-04 | 11 |
| GO:0043370 | regulation of CD4-positive, alpha-beta T cell differentiation | 6/184 | 55/18614 | 0 | 5e-04 | 6 |
| GO:0009611 | response to wounding | 18/184 | 575/18614 | 0 | 5e-04 | 18 |
| GO:0051047 | positive regulation of secretion | 13/184 | 317/18614 | 0 | 5e-04 | 13 |
| GO:0050817 | coagulation | 11/184 | 229/18614 | 0 | 5e-04 | 11 |
| GO:0016050 | vesicle organization | 14/184 | 368/18614 | 0 | 5e-04 | 14 |
| GO:0022409 | positive regulation of cell-cell adhesion | 13/184 | 321/18614 | 0 | 6e-04 | 13 |
| GO:0061515 | myeloid cell development | 7/184 | 84/18614 | 0 | 6e-04 | 7 |
| GO:0030099 | myeloid cell differentiation | 15/184 | 421/18614 | 0 | 6e-04 | 15 |
| GO:0006897 | endocytosis | 18/184 | 583/18614 | 0 | 6e-04 | 18 |
| GO:0060627 | regulation of vesicle-mediated transport | 17/184 | 530/18614 | 0 | 6e-04 | 17 |
| GO:0070997 | neuron death | 14/184 | 373/18614 | 0 | 6e-04 | 14 |
| GO:0002718 | regulation of cytokine production involved in immune response | 8/184 | 119/18614 | 0 | 7e-04 | 8 |
| GO:1903037 | regulation of leukocyte cell-cell adhesion | 14/184 | 378/18614 | 0 | 7e-04 | 14 |
| GO:0045064 | T-helper 2 cell differentiation | 4/184 | 18/18614 | 0 | 7e-04 | 4 |
| GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 9/184 | 156/18614 | 0 | 7e-04 | 9 |
| GO:0045861 | negative regulation of proteolysis | 13/184 | 330/18614 | 0 | 7e-04 | 13 |
| GO:0043542 | endothelial cell migration | 12/184 | 283/18614 | 0 | 7e-04 | 12 |
| GO:0002367 | cytokine production involved in immune response | 8/184 | 121/18614 | 0 | 7e-04 | 8 |
| GO:0043367 | CD4-positive, alpha-beta T cell differentiation | 7/184 | 89/18614 | 0 | 8e-04 | 7 |
| GO:0001819 | positive regulation of cytokine production | 16/184 | 489/18614 | 0 | 8e-04 | 16 |
| GO:0052548 | regulation of endopeptidase activity | 13/184 | 336/18614 | 0 | 8e-04 | 13 |
| GO:0032944 | regulation of mononuclear cell proliferation | 11/184 | 243/18614 | 0 | 8e-04 | 11 |
| GO:0001934 | positive regulation of protein phosphorylation | 20/184 | 720/18614 | 0 | 8e-04 | 20 |
| GO:0010744 | positive regulation of macrophage derived foam cell differentiation | 4/184 | 19/18614 | 0 | 8e-04 | 4 |
| GO:0042060 | wound healing | 15/184 | 439/18614 | 0 | 8e-04 | 15 |
| GO:0009205 | purine ribonucleoside triphosphate metabolic process | 11/184 | 244/18614 | 0 | 8e-04 | 11 |
| GO:0002521 | leukocyte differentiation | 18/184 | 605/18614 | 0 | 8e-04 | 18 |
| GO:0031623 | receptor internalization | 8/184 | 125/18614 | 0 | 8e-04 | 8 |
| GO:0010742 | macrophage derived foam cell differentiation | 5/184 | 38/18614 | 0 | 8e-04 | 5 |
| GO:0001667 | ameboidal-type cell migration | 16/184 | 496/18614 | 0 | 9e-04 | 16 |
| GO:0031401 | positive regulation of protein modification process | 24/184 | 976/18614 | 0 | 9e-04 | 24 |
| GO:0042327 | positive regulation of phosphorylation | 21/184 | 788/18614 | 0 | 9e-04 | 21 |
| GO:0055086 | nucleobase-containing small molecule metabolic process | 19/184 | 668/18614 | 0 | 9e-04 | 19 |
| GO:0009144 | purine nucleoside triphosphate metabolic process | 11/184 | 249/18614 | 0 | 9e-04 | 11 |
| GO:0090077 | foam cell differentiation | 5/184 | 39/18614 | 0 | 9e-04 | 5 |
| GO:0097242 | amyloid-beta clearance | 5/184 | 39/18614 | 0 | 9e-04 | 5 |
| GO:0051346 | negative regulation of hydrolase activity | 13/184 | 345/18614 | 0 | 1e-03 | 13 |
| GO:0070665 | positive regulation of leukocyte proliferation | 9/184 | 166/18614 | 0 | 1e-03 | 9 |
| GO:0009199 | ribonucleoside triphosphate metabolic process | 11/184 | 251/18614 | 0 | 1e-03 | 11 |
| GO:0097305 | response to alcohol | 11/184 | 252/18614 | 0 | 1e-03 | 11 |