Whether to apply row-scaling on the matrix affects the clustering step in consensus partitioning, which might give different partition results on the samples. For the expression matrices, we recommend to scale rows because the more interesting thing is the subgrouping where genes show similar expression patterns in the sense of e.g. genes showing consistent up-regulation in the subgroups. If the rows are not scaled, the partitions are more generally affected by highly expressed genes.
In this analysis, we performed cola analysis on Golub Leukemia dataset by applying row-scaling on the matrix and not. The choice of row-scaling can be tuned by setting scale_rows
to TRUE
or FALSE
in run_all_consensus_partition_methods()
or consensus_partition()
function.
For the partition methods hclust
, kmeans
, skmeans
, pam
and mclust
, z-score scaling is applied as \((x-\mu)/\sigma\), and for NMF
, the “min-max” scalling is applied as (x - min)/(max - min)
.
Figure S10.1A and 1B (switching the tabs in the following figure) illustrate consensus heatmaps for two-group classification with or without row-scaling. Table 1 lists the stability of consensus partition under different methods (measured by 1-PAC scores):
Rows are scaled | Rows are unscaled | |
---|---|---|
ATC:skmeans | 1 | 0.67 |
ATC:kmeans | 1 | 0.66 |
ATC:NMF | 0.97 | 0.55 |
SD:skmeans | 0.62 | 1 |
CV:skmeans | 0.63 | 1 |
MAD:skmeans | 0.64 | 1 |
SD:kmeans | 0.66 | 1 |
CV:kmeans | 0.65 | 1 |
MAD:kmeans | 0.62 | 1 |
CV:mclust | 0.49 | 0.98 |
MAD:mclust | 0.82 | 0.96 |
SD:mclust | 0.37 | 0.74 |
CV:NMF | 0.63 | 0.68 |
MAD:NMF | 0.68 | 0.65 |
SD:NMF | 0.63 | 0.63 |
SD:pam | 0.55 | 0.62 |
MAD:pam | 0.65 | 0.58 |
CV:pam | 0.55 | 0.55 |
MAD:hclust | 0.23 | 0.53 |
ATC:pam | 0.6 | 0.51 |
SD:hclust | 0.24 | 0.44 |
ATC:hclust | 0.57 | 0.4 |
CV:hclust | 0.21 | 0.38 |
ATC:mclust | 0.36 | 0.36 |
A quick look shows the partitioning results are different when rows are scaled and not. We will discuss with more details in the next section.
Figure S10.2 puts classifications from all 24 methods together as well as one clinical annotation. The annotation ALL.AML
tells whether the patient (the sample) had ALL or AML. The lightness of the main heatmap corresponds to the silhouette scores for samples measured in each partitioning method. With lighter color, the less stable for the sample to stay in its group.
When the matrix rows are scaled (top heatmap in Figure S10.2), there are two major sets of different classifications where methods integrated with mclust
, kmeans
, and NMF
classify samples into two groups where one group mainly contains AML samples. Other methods integrated with ATC
, skmeans
and pam
generate classifications where a subset of ALL samples move to the same group of AML samples. Although there are two different two-group classifications, the samples that have different classifications among methods generally have lower silhouette scores in the corresponding consensus partition runs ( i.e. the colors in the heatmap are lighter), which means, they are less confident samples for the classifications and different partition methods might classify them into different groups.
When the matrix are not scaled (bottom heatmap in Figure S10.2), the pattern is similar that there are also two sets of classifications. The difference to the top heatmap is now the partitions where features are selected based on row variance (SD
/CV
/MAD
) are more stable in the consensus partitioning procedure while partitions with features selected by ATC are less stable.
Comparing classifications from row-scaling and non-row-scaling, the classifications are similar for both cases. Basically we can make the conclusion that, when rows are scaled, methods with ATC
give more stable partitions and when rows are not scaled, methods with SD
/CV
/MAD
give more stable partitions.
To look closer on the different impact on consensus partitioning of applying row-scaling or not, we select the results by ATC:skmeans
for the case when matrix rows are scaled and the results by MAD:kmeans
for the case when matrix rows are not scaled. The partitionings are stable for the two methods in their settings. Figure S10.3 illustrates how the two classifications correspond.
We can confirm that MAD:kmeans, row unscaled
classification fits very well to the AML/ALL classification, while a subset of ALL samples are classified as the same group as AML samples for the ATC:skmeans, row scaled
classification (the green samples on the most right side).
To make it easier to describe, we term the classification from the scaled matrix as \(C_{s, 2}\) (or C_{s,2} if it cannot be rendered as math symbols) and the classification from the unscaled matrix as \(C_{u,2}\) (or C_{u,2}).
We can confirm the separation of the two groups by PCA visualization. PCA is applied to the scaled matrix in Figure S10.4A and to the unscaled matrix in Figure S10.4B. The two plots shows the two classifications can both separate samples very well and seem very reasonable.
Since there are two different classifications, we can next look at the signature genes that are significantly differentially expressed in the two groups, i.e. to compare the signature genes that support the two different classifications.
In Figure S10.5A and S10.5B, the significant genes are simply selected by t-test (FDR < 0.05). According to the heatmaps illustrated in Figure S10.5A and S10.5B, it seems the two different classification are all reasonable that there are many significant genes supporting them, although the number of significant genes in \(C_{s,2}\) are approximate 2 fold more than in \(C_{u,2}\).
The two sets of signature genes have quite large overlap, and they also have their own unique set of genes. \(C_{s,2}\) has 1106 (61%) specific genes and \(C_{u,2}\) has 353 (33%) specific genes (Figure S10.6).
To see the difference of the three sets of signature genes in Figure S10.6, we make heatmaps for the signature genes specific in classification \(C_{s, 2}\), specific in \(C_{u, 2}\) and those common in the two classifications.
As illustrated in Figure S10.7A and S10.7C, the expression patterns for the signature genes specific in \(C_{s,2}\) or \(C_{u,2}\) are clean that the samples are not separable in the other classification, while in Figure S10.7B where the signature genes are shared by the two classifications, the signature genes show intermeidate expression patterns in the samples that disagree in the two classifcations, they can be classified to different groups by different methods.
We term the three categories of signature genes as group A/B/C and we apply Gene Ontology enrichment to the three set of genes by hypergenometric test (with the clusterProfiler package). We only use BP ontologies (Biological Process) and the significant GO terms are filtered by FDR < 0.01. The enriched GO terms are visualized as a heatmap in Figure S10.8 by their similarities between GO terms (with GOSemSim package). GO terms are split and clustered with the simplifyEnrichment package. The keywords of the summaries of GO functions in each cluster are visualized by word clouds.
Again, Figure S10.8 illustrates each set of genes have quite a lot enriched GO terms, which might imply both classification are biologically reasonable.
The complete list of the GO enrichment can be found at the end of this supplementary.
As a conclusion for the two-group classification analysis on Golub dataset, we can make following conclusions:
ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
---|---|---|---|---|---|---|
GO:0009725 | response to hormone | 119/885 | 987/18670 | 0.0000 | 0.0000 | 119 |
GO:0051050 | positive regulation of transport | 115/885 | 982/18670 | 0.0000 | 0.0000 | 115 |
GO:0010243 | response to organonitrogen compound | 110/885 | 998/18670 | 0.0000 | 0.0000 | 110 |
GO:1901652 | response to peptide | 68/885 | 520/18670 | 0.0000 | 0.0000 | 68 |
GO:0071417 | cellular response to organonitrogen compound | 73/885 | 585/18670 | 0.0000 | 0.0000 | 73 |
GO:0033993 | response to lipid | 98/885 | 923/18670 | 0.0000 | 0.0000 | 98 |
GO:1901699 | cellular response to nitrogen compound | 76/885 | 648/18670 | 0.0000 | 0.0000 | 76 |
GO:0014070 | response to organic cyclic compound | 95/885 | 915/18670 | 0.0000 | 0.0000 | 95 |
GO:0070482 | response to oxygen levels | 55/885 | 394/18670 | 0.0000 | 0.0000 | 55 |
GO:0019725 | cellular homeostasis | 98/885 | 970/18670 | 0.0000 | 0.0000 | 98 |
GO:0023061 | signal release | 60/885 | 462/18670 | 0.0000 | 0.0000 | 60 |
GO:0051046 | regulation of secretion | 86/885 | 811/18670 | 0.0000 | 0.0000 | 86 |
GO:1903530 | regulation of secretion by cell | 81/885 | 753/18670 | 0.0000 | 0.0000 | 81 |
GO:1901653 | cellular response to peptide | 52/885 | 385/18670 | 0.0000 | 0.0000 | 52 |
GO:0043434 | response to peptide hormone | 56/885 | 436/18670 | 0.0000 | 0.0000 | 56 |
GO:0032870 | cellular response to hormone stimulus | 76/885 | 701/18670 | 0.0000 | 0.0000 | 76 |
GO:0009611 | response to wounding | 74/885 | 678/18670 | 0.0000 | 0.0000 | 74 |
GO:0036293 | response to decreased oxygen levels | 50/885 | 370/18670 | 0.0000 | 0.0000 | 50 |
GO:0001666 | response to hypoxia | 49/885 | 359/18670 | 0.0000 | 0.0000 | 49 |
GO:0046879 | hormone secretion | 45/885 | 312/18670 | 0.0000 | 0.0000 | 45 |
GO:0055082 | cellular chemical homeostasis | 83/885 | 812/18670 | 0.0000 | 0.0000 | 83 |
GO:0030072 | peptide hormone secretion | 39/885 | 250/18670 | 0.0000 | 0.0000 | 39 |
GO:0009914 | hormone transport | 45/885 | 322/18670 | 0.0000 | 0.0000 | 45 |
GO:0090087 | regulation of peptide transport | 76/885 | 729/18670 | 0.0000 | 0.0000 | 76 |
GO:0046887 | positive regulation of hormone secretion | 27/885 | 131/18670 | 0.0000 | 0.0000 | 27 |
GO:0046883 | regulation of hormone secretion | 40/885 | 266/18670 | 0.0000 | 0.0000 | 40 |
GO:0010817 | regulation of hormone levels | 61/885 | 529/18670 | 0.0000 | 0.0000 | 61 |
GO:0002790 | peptide secretion | 68/885 | 624/18670 | 0.0000 | 0.0000 | 68 |
GO:0043066 | negative regulation of apoptotic process | 88/885 | 911/18670 | 0.0000 | 0.0000 | 88 |
GO:0009636 | response to toxic substance | 60/885 | 525/18670 | 0.0000 | 0.0000 | 60 |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 74/885 | 719/18670 | 0.0000 | 0.0000 | 74 |
GO:0061564 | axon development | 59/885 | 514/18670 | 0.0000 | 0.0000 | 59 |
GO:0051098 | regulation of binding | 48/885 | 373/18670 | 0.0000 | 0.0000 | 48 |
GO:1903532 | positive regulation of secretion by cell | 50/885 | 399/18670 | 0.0000 | 0.0000 | 50 |
GO:0043069 | negative regulation of programmed cell death | 88/885 | 932/18670 | 0.0000 | 0.0000 | 88 |
GO:0007409 | axonogenesis | 55/885 | 468/18670 | 0.0000 | 0.0000 | 55 |
GO:0003013 | circulatory system process | 61/885 | 551/18670 | 0.0000 | 0.0000 | 61 |
GO:0042391 | regulation of membrane potential | 52/885 | 434/18670 | 0.0000 | 0.0000 | 52 |
GO:0048732 | gland development | 52/885 | 434/18670 | 0.0000 | 0.0000 | 52 |
GO:0006936 | muscle contraction | 46/885 | 360/18670 | 0.0000 | 0.0000 | 46 |
GO:0090276 | regulation of peptide hormone secretion | 33/885 | 208/18670 | 0.0000 | 0.0000 | 33 |
GO:0048729 | tissue morphogenesis | 69/885 | 670/18670 | 0.0000 | 0.0000 | 69 |
GO:0051047 | positive regulation of secretion | 51/885 | 428/18670 | 0.0000 | 0.0000 | 51 |
GO:0072507 | divalent inorganic cation homeostasis | 57/885 | 513/18670 | 0.0000 | 0.0000 | 57 |
GO:0008015 | blood circulation | 59/885 | 541/18670 | 0.0000 | 0.0000 | 59 |
GO:0071375 | cellular response to peptide hormone stimulus | 42/885 | 321/18670 | 0.0000 | 0.0000 | 42 |
GO:0048545 | response to steroid hormone | 47/885 | 385/18670 | 0.0000 | 0.0000 | 47 |
GO:0008285 | negative regulation of cell proliferation | 74/885 | 760/18670 | 0.0000 | 0.0000 | 74 |
GO:0003012 | muscle system process | 53/885 | 465/18670 | 0.0000 | 0.0000 | 53 |
GO:0070201 | regulation of establishment of protein localization | 73/885 | 746/18670 | 0.0000 | 0.0000 | 73 |
GO:0099536 | synaptic signaling | 71/885 | 717/18670 | 0.0000 | 0.0000 | 71 |
GO:0060322 | head development | 75/885 | 776/18670 | 0.0000 | 0.0000 | 75 |
GO:0072503 | cellular divalent inorganic cation homeostasis | 55/885 | 493/18670 | 0.0000 | 0.0000 | 55 |
GO:0048534 | hematopoietic or lymphoid organ development | 85/885 | 929/18670 | 0.0000 | 0.0000 | 85 |
GO:0006875 | cellular metal ion homeostasis | 61/885 | 579/18670 | 0.0000 | 0.0000 | 61 |
GO:0044419 | interspecies interaction between organisms | 85/885 | 932/18670 | 0.0000 | 0.0000 | 85 |
GO:0030003 | cellular cation homeostasis | 66/885 | 652/18670 | 0.0000 | 0.0000 | 66 |
GO:0002791 | regulation of peptide secretion | 55/885 | 500/18670 | 0.0000 | 0.0000 | 55 |
GO:0060341 | regulation of cellular localization | 83/885 | 906/18670 | 0.0000 | 0.0000 | 83 |
GO:0002520 | immune system development | 88/885 | 985/18670 | 0.0000 | 0.0000 | 88 |
GO:0007268 | chemical synaptic transmission | 69/885 | 703/18670 | 0.0000 | 0.0000 | 69 |
GO:0098916 | anterograde trans-synaptic signaling | 69/885 | 703/18670 | 0.0000 | 0.0000 | 69 |
GO:0032868 | response to insulin | 37/885 | 272/18670 | 0.0000 | 0.0000 | 37 |
GO:0009306 | protein secretion | 61/885 | 591/18670 | 0.0000 | 0.0000 | 61 |
GO:0030097 | hemopoiesis | 81/885 | 887/18670 | 0.0000 | 0.0000 | 81 |
GO:0006873 | cellular ion homeostasis | 66/885 | 665/18670 | 0.0000 | 0.0000 | 66 |
GO:0035239 | tube morphogenesis | 83/885 | 920/18670 | 0.0000 | 0.0000 | 83 |
GO:0008284 | positive regulation of cell proliferation | 85/885 | 951/18670 | 0.0000 | 0.0000 | 85 |
GO:0099537 | trans-synaptic signaling | 69/885 | 711/18670 | 0.0000 | 0.0000 | 69 |
GO:0072358 | cardiovascular system development | 75/885 | 801/18670 | 0.0000 | 0.0000 | 75 |
GO:0009743 | response to carbohydrate | 33/885 | 230/18670 | 0.0000 | 0.0000 | 33 |
GO:0043269 | regulation of ion transport | 68/885 | 699/18670 | 0.0000 | 0.0000 | 68 |
GO:0051223 | regulation of protein transport | 68/885 | 699/18670 | 0.0000 | 0.0000 | 68 |
GO:0001944 | vasculature development | 74/885 | 792/18670 | 0.0000 | 0.0000 | 74 |
GO:0090277 | positive regulation of peptide hormone secretion | 20/885 | 96/18670 | 0.0000 | 0.0000 | 20 |
GO:0032386 | regulation of intracellular transport | 48/885 | 423/18670 | 0.0000 | 0.0000 | 48 |
GO:0120039 | plasma membrane bounded cell projection morphogenesis | 65/885 | 662/18670 | 0.0000 | 0.0000 | 65 |
GO:0048812 | neuron projection morphogenesis | 64/885 | 648/18670 | 0.0000 | 0.0000 | 64 |
GO:0048511 | rhythmic process | 38/885 | 295/18670 | 0.0000 | 0.0000 | 38 |
GO:0018209 | peptidyl-serine modification | 40/885 | 322/18670 | 0.0000 | 0.0000 | 40 |
GO:0048858 | cell projection morphogenesis | 65/885 | 666/18670 | 0.0000 | 0.0000 | 65 |
GO:0055065 | metal ion homeostasis | 64/885 | 653/18670 | 0.0000 | 0.0000 | 64 |
GO:1904951 | positive regulation of establishment of protein localization | 50/885 | 456/18670 | 0.0000 | 0.0000 | 50 |
GO:0048667 | cell morphogenesis involved in neuron differentiation | 59/885 | 583/18670 | 0.0000 | 0.0000 | 59 |
GO:0055074 | calcium ion homeostasis | 51/885 | 471/18670 | 0.0000 | 0.0000 | 51 |
GO:0055080 | cation homeostasis | 69/885 | 730/18670 | 0.0000 | 0.0000 | 69 |
GO:0006935 | chemotaxis | 63/885 | 644/18670 | 0.0000 | 0.0000 | 63 |
GO:0031175 | neuron projection development | 85/885 | 978/18670 | 0.0000 | 0.0000 | 85 |
GO:0007420 | brain development | 69/885 | 733/18670 | 0.0000 | 0.0000 | 69 |
GO:0042330 | taxis | 63/885 | 646/18670 | 0.0000 | 0.0000 | 63 |
GO:0030073 | insulin secretion | 30/885 | 207/18670 | 0.0000 | 0.0000 | 30 |
GO:0050804 | modulation of chemical synaptic transmission | 48/885 | 436/18670 | 0.0000 | 0.0000 | 48 |
GO:0009266 | response to temperature stimulus | 33/885 | 243/18670 | 0.0000 | 0.0000 | 33 |
GO:0099177 | regulation of trans-synaptic signaling | 48/885 | 437/18670 | 0.0000 | 0.0000 | 48 |
GO:0098771 | inorganic ion homeostasis | 69/885 | 741/18670 | 0.0000 | 0.0000 | 69 |
GO:0048863 | stem cell differentiation | 34/885 | 257/18670 | 0.0000 | 0.0000 | 34 |
GO:0071453 | cellular response to oxygen levels | 32/885 | 234/18670 | 0.0000 | 0.0000 | 32 |
GO:0032101 | regulation of response to external stimulus | 80/885 | 913/18670 | 0.0000 | 0.0000 | 80 |
GO:0034762 | regulation of transmembrane transport | 57/885 | 568/18670 | 0.0000 | 0.0000 | 57 |
GO:0032990 | cell part morphogenesis | 65/885 | 685/18670 | 0.0000 | 0.0000 | 65 |
GO:0098657 | import into cell | 82/885 | 945/18670 | 0.0000 | 0.0000 | 82 |
GO:0030001 | metal ion transport | 78/885 | 883/18670 | 0.0000 | 0.0000 | 78 |
GO:0001568 | blood vessel development | 70/885 | 761/18670 | 0.0000 | 0.0000 | 70 |
GO:0044057 | regulation of system process | 60/885 | 613/18670 | 0.0000 | 0.0000 | 60 |
GO:0071407 | cellular response to organic cyclic compound | 55/885 | 542/18670 | 0.0000 | 0.0000 | 55 |
GO:0006874 | cellular calcium ion homeostasis | 49/885 | 458/18670 | 0.0000 | 0.0000 | 49 |
GO:0045471 | response to ethanol | 22/885 | 125/18670 | 0.0000 | 0.0000 | 22 |
GO:0018105 | peptidyl-serine phosphorylation | 37/885 | 299/18670 | 0.0000 | 0.0000 | 37 |
GO:0050878 | regulation of body fluid levels | 52/885 | 501/18670 | 0.0000 | 0.0000 | 52 |
GO:0050801 | ion homeostasis | 73/885 | 811/18670 | 0.0000 | 0.0000 | 73 |
GO:0097190 | apoptotic signaling pathway | 59/885 | 602/18670 | 0.0000 | 0.0000 | 59 |
GO:0071363 | cellular response to growth factor stimulus | 66/885 | 706/18670 | 0.0000 | 0.0000 | 66 |
GO:0043270 | positive regulation of ion transport | 35/885 | 275/18670 | 0.0000 | 0.0000 | 35 |
GO:0002793 | positive regulation of peptide secretion | 36/885 | 288/18670 | 0.0000 | 0.0000 | 36 |
GO:2001233 | regulation of apoptotic signaling pathway | 45/885 | 406/18670 | 0.0000 | 0.0000 | 45 |
GO:0046677 | response to antibiotic | 39/885 | 327/18670 | 0.0000 | 0.0000 | 39 |
GO:0001505 | regulation of neurotransmitter levels | 41/885 | 354/18670 | 0.0000 | 0.0000 | 41 |
GO:0032869 | cellular response to insulin stimulus | 30/885 | 216/18670 | 0.0000 | 0.0000 | 30 |
GO:0048514 | blood vessel morphogenesis | 64/885 | 681/18670 | 0.0000 | 0.0000 | 64 |
GO:0042593 | glucose homeostasis | 32/885 | 241/18670 | 0.0000 | 0.0000 | 32 |
GO:0033500 | carbohydrate homeostasis | 32/885 | 242/18670 | 0.0000 | 0.0000 | 32 |
GO:0071396 | cellular response to lipid | 59/885 | 610/18670 | 0.0000 | 0.0000 | 59 |
GO:0030855 | epithelial cell differentiation | 70/885 | 775/18670 | 0.0000 | 0.0000 | 70 |
GO:0044403 | symbiont process | 77/885 | 884/18670 | 0.0000 | 0.0000 | 77 |
GO:0034284 | response to monosaccharide | 29/885 | 207/18670 | 0.0000 | 0.0000 | 29 |
GO:0009894 | regulation of catabolic process | 83/885 | 979/18670 | 0.0000 | 0.0000 | 83 |
GO:0031347 | regulation of defense response | 78/885 | 901/18670 | 0.0000 | 0.0000 | 78 |
GO:0009749 | response to glucose | 28/885 | 197/18670 | 0.0000 | 0.0000 | 28 |
GO:0070848 | response to growth factor | 67/885 | 736/18670 | 0.0000 | 0.0000 | 67 |
GO:0001525 | angiogenesis | 57/885 | 587/18670 | 0.0000 | 0.0000 | 57 |
GO:0007507 | heart development | 57/885 | 587/18670 | 0.0000 | 0.0000 | 57 |
GO:0015672 | monovalent inorganic cation transport | 53/885 | 529/18670 | 0.0000 | 0.0000 | 53 |
GO:1903522 | regulation of blood circulation | 36/885 | 297/18670 | 0.0000 | 0.0000 | 36 |
GO:0048608 | reproductive structure development | 46/885 | 431/18670 | 0.0000 | 0.0000 | 46 |
GO:0051222 | positive regulation of protein transport | 45/885 | 418/18670 | 0.0000 | 0.0000 | 45 |
GO:0006954 | inflammatory response | 74/885 | 848/18670 | 0.0000 | 0.0000 | 74 |
GO:0061458 | reproductive system development | 46/885 | 434/18670 | 0.0000 | 0.0000 | 46 |
GO:0090066 | regulation of anatomical structure size | 51/885 | 506/18670 | 0.0000 | 0.0000 | 51 |
GO:0001816 | cytokine production | 70/885 | 790/18670 | 0.0000 | 0.0000 | 70 |
GO:0000904 | cell morphogenesis involved in differentiation | 67/885 | 744/18670 | 0.0000 | 0.0000 | 67 |
GO:1902803 | regulation of synaptic vesicle transport | 17/885 | 84/18670 | 0.0000 | 0.0000 | 17 |
GO:0009746 | response to hexose | 28/885 | 202/18670 | 0.0000 | 0.0000 | 28 |
GO:0002009 | morphogenesis of an epithelium | 53/885 | 537/18670 | 0.0000 | 0.0000 | 53 |
GO:0031329 | regulation of cellular catabolic process | 75/885 | 871/18670 | 0.0000 | 0.0000 | 75 |
GO:0043065 | positive regulation of apoptotic process | 62/885 | 672/18670 | 0.0000 | 0.0000 | 62 |
GO:0019932 | second-messenger-mediated signaling | 46/885 | 439/18670 | 0.0000 | 0.0000 | 46 |
GO:0036294 | cellular response to decreased oxygen levels | 29/885 | 217/18670 | 0.0000 | 0.0000 | 29 |
GO:0031667 | response to nutrient levels | 50/885 | 499/18670 | 0.0000 | 0.0000 | 50 |
GO:0006937 | regulation of muscle contraction | 25/885 | 171/18670 | 0.0000 | 0.0000 | 25 |
GO:0000165 | MAPK cascade | 80/885 | 958/18670 | 0.0000 | 0.0000 | 80 |
GO:0033674 | positive regulation of kinase activity | 55/885 | 573/18670 | 0.0000 | 0.0000 | 55 |
GO:0071456 | cellular response to hypoxia | 28/885 | 207/18670 | 0.0000 | 0.0000 | 28 |
GO:0099003 | vesicle-mediated transport in synapse | 28/885 | 207/18670 | 0.0000 | 0.0000 | 28 |
GO:0006836 | neurotransmitter transport | 33/885 | 269/18670 | 0.0000 | 0.0000 | 33 |
GO:0016032 | viral process | 72/885 | 833/18670 | 0.0000 | 0.0000 | 72 |
GO:0006942 | regulation of striated muscle contraction | 18/885 | 97/18670 | 0.0000 | 0.0000 | 18 |
GO:0043068 | positive regulation of programmed cell death | 62/885 | 680/18670 | 0.0000 | 0.0000 | 62 |
GO:0016579 | protein deubiquitination | 34/885 | 283/18670 | 0.0000 | 0.0000 | 34 |
GO:0003018 | vascular process in circulatory system | 25/885 | 173/18670 | 0.0000 | 0.0000 | 25 |
GO:0007159 | leukocyte cell-cell adhesion | 38/885 | 337/18670 | 0.0000 | 0.0000 | 38 |
GO:0006941 | striated muscle contraction | 25/885 | 174/18670 | 0.0000 | 0.0000 | 25 |
GO:0042060 | wound healing | 54/885 | 564/18670 | 0.0000 | 0.0000 | 54 |
GO:0070646 | protein modification by small protein removal | 35/885 | 299/18670 | 0.0000 | 0.0000 | 35 |
GO:0010959 | regulation of metal ion transport | 42/885 | 394/18670 | 0.0000 | 0.0000 | 42 |
GO:0023014 | signal transduction by protein phosphorylation | 80/885 | 969/18670 | 0.0000 | 0.0000 | 80 |
GO:0009408 | response to heat | 25/885 | 176/18670 | 0.0000 | 0.0000 | 25 |
GO:0050796 | regulation of insulin secretion | 25/885 | 176/18670 | 0.0000 | 0.0000 | 25 |
GO:0007411 | axon guidance | 33/885 | 276/18670 | 0.0000 | 0.0000 | 33 |
GO:0097485 | neuron projection guidance | 33/885 | 277/18670 | 0.0000 | 0.0000 | 33 |
GO:0071214 | cellular response to abiotic stimulus | 37/885 | 331/18670 | 0.0000 | 0.0000 | 37 |
GO:0104004 | cellular response to environmental stimulus | 37/885 | 331/18670 | 0.0000 | 0.0000 | 37 |
GO:0051347 | positive regulation of transferase activity | 59/885 | 649/18670 | 0.0000 | 0.0000 | 59 |
GO:0050708 | regulation of protein secretion | 47/885 | 472/18670 | 0.0000 | 0.0000 | 47 |
GO:0009991 | response to extracellular stimulus | 51/885 | 531/18670 | 0.0000 | 0.0000 | 51 |
GO:0043393 | regulation of protein binding | 28/885 | 217/18670 | 0.0000 | 0.0000 | 28 |
GO:0010942 | positive regulation of cell death | 64/885 | 730/18670 | 0.0000 | 0.0001 | 64 |
GO:0007568 | aging | 36/885 | 321/18670 | 0.0000 | 0.0001 | 36 |
GO:0040007 | growth | 80/885 | 986/18670 | 0.0000 | 0.0001 | 80 |
GO:0060048 | cardiac muscle contraction | 21/885 | 137/18670 | 0.0000 | 0.0001 | 21 |
GO:0019221 | cytokine-mediated signaling pathway | 68/885 | 798/18670 | 0.0000 | 0.0001 | 68 |
GO:0045597 | positive regulation of cell differentiation | 80/885 | 991/18670 | 0.0000 | 0.0001 | 80 |
GO:0090257 | regulation of muscle system process | 31/885 | 259/18670 | 0.0000 | 0.0001 | 31 |
GO:0007188 | adenylate cyclase-modulating G protein-coupled receptor signaling pathway | 28/885 | 221/18670 | 0.0000 | 0.0001 | 28 |
GO:2000736 | regulation of stem cell differentiation | 19/885 | 116/18670 | 0.0000 | 0.0001 | 19 |
GO:0009755 | hormone-mediated signaling pathway | 29/885 | 235/18670 | 0.0000 | 0.0001 | 29 |
GO:0051588 | regulation of neurotransmitter transport | 21/885 | 139/18670 | 0.0000 | 0.0001 | 21 |
GO:0060078 | regulation of postsynaptic membrane potential | 21/885 | 140/18670 | 0.0000 | 0.0001 | 21 |
GO:0050778 | positive regulation of immune response | 74/885 | 902/18670 | 0.0000 | 0.0001 | 74 |
GO:0001101 | response to acid chemical | 37/885 | 343/18670 | 0.0000 | 0.0001 | 37 |
GO:0006887 | exocytosis | 74/885 | 903/18670 | 0.0000 | 0.0001 | 74 |
GO:0003015 | heart process | 33/885 | 290/18670 | 0.0000 | 0.0001 | 33 |
GO:0008016 | regulation of heart contraction | 30/885 | 251/18670 | 0.0000 | 0.0001 | 30 |
GO:0060627 | regulation of vesicle-mediated transport | 50/885 | 532/18670 | 0.0000 | 0.0001 | 50 |
GO:2000300 | regulation of synaptic vesicle exocytosis | 15/885 | 78/18670 | 0.0000 | 0.0001 | 15 |
GO:1903706 | regulation of hemopoiesis | 46/885 | 475/18670 | 0.0000 | 0.0001 | 46 |
GO:0050852 | T cell receptor signaling pathway | 26/885 | 202/18670 | 0.0000 | 0.0001 | 26 |
GO:0045785 | positive regulation of cell adhesion | 41/885 | 403/18670 | 0.0000 | 0.0001 | 41 |
GO:2000027 | regulation of animal organ morphogenesis | 30/885 | 253/18670 | 0.0000 | 0.0001 | 30 |
GO:0051090 | regulation of DNA-binding transcription factor activity | 43/885 | 432/18670 | 0.0000 | 0.0001 | 43 |
GO:0045786 | negative regulation of cell cycle | 57/885 | 641/18670 | 0.0000 | 0.0001 | 57 |
GO:0001817 | regulation of cytokine production | 62/885 | 719/18670 | 0.0000 | 0.0001 | 62 |
GO:0035296 | regulation of tube diameter | 21/885 | 143/18670 | 0.0000 | 0.0001 | 21 |
GO:0050880 | regulation of blood vessel size | 21/885 | 143/18670 | 0.0000 | 0.0001 | 21 |
GO:0097746 | regulation of blood vessel diameter | 21/885 | 143/18670 | 0.0000 | 0.0001 | 21 |
GO:0048771 | tissue remodeling | 24/885 | 179/18670 | 0.0000 | 0.0001 | 24 |
GO:0051051 | negative regulation of transport | 49/885 | 522/18670 | 0.0000 | 0.0001 | 49 |
GO:0022898 | regulation of transmembrane transporter activity | 31/885 | 268/18670 | 0.0000 | 0.0001 | 31 |
GO:0035150 | regulation of tube size | 21/885 | 144/18670 | 0.0000 | 0.0001 | 21 |
GO:0071322 | cellular response to carbohydrate stimulus | 21/885 | 144/18670 | 0.0000 | 0.0001 | 21 |
GO:0022409 | positive regulation of cell-cell adhesion | 30/885 | 255/18670 | 0.0000 | 0.0001 | 30 |
GO:0034764 | positive regulation of transmembrane transport | 26/885 | 204/18670 | 0.0000 | 0.0001 | 26 |
GO:0001656 | metanephros development | 16/885 | 90/18670 | 0.0000 | 0.0001 | 16 |
GO:2001234 | negative regulation of apoptotic signaling pathway | 28/885 | 230/18670 | 0.0000 | 0.0001 | 28 |
GO:0017144 | drug metabolic process | 70/885 | 851/18670 | 0.0000 | 0.0001 | 70 |
GO:0002253 | activation of immune response | 62/885 | 724/18670 | 0.0000 | 0.0001 | 62 |
GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 27/885 | 218/18670 | 0.0000 | 0.0001 | 27 |
GO:0098660 | inorganic ion transmembrane transport | 69/885 | 836/18670 | 0.0000 | 0.0001 | 69 |
GO:0098693 | regulation of synaptic vesicle cycle | 18/885 | 112/18670 | 0.0000 | 0.0001 | 18 |
GO:0033238 | regulation of cellular amine metabolic process | 15/885 | 81/18670 | 0.0000 | 0.0001 | 15 |
GO:0043549 | regulation of kinase activity | 71/885 | 870/18670 | 0.0000 | 0.0001 | 71 |
GO:0098655 | cation transmembrane transport | 70/885 | 855/18670 | 0.0000 | 0.0001 | 70 |
GO:0070838 | divalent metal ion transport | 46/885 | 483/18670 | 0.0000 | 0.0001 | 46 |
GO:0051101 | regulation of DNA binding | 19/885 | 124/18670 | 0.0000 | 0.0002 | 19 |
GO:0050900 | leukocyte migration | 47/885 | 499/18670 | 0.0000 | 0.0002 | 47 |
GO:0055117 | regulation of cardiac muscle contraction | 15/885 | 82/18670 | 0.0000 | 0.0002 | 15 |
GO:0050670 | regulation of lymphocyte proliferation | 26/885 | 208/18670 | 0.0000 | 0.0002 | 26 |
GO:0045055 | regulated exocytosis | 66/885 | 794/18670 | 0.0000 | 0.0002 | 66 |
GO:0032944 | regulation of mononuclear cell proliferation | 26/885 | 209/18670 | 0.0000 | 0.0002 | 26 |
GO:0070663 | regulation of leukocyte proliferation | 27/885 | 222/18670 | 0.0000 | 0.0002 | 27 |
GO:0045860 | positive regulation of protein kinase activity | 49/885 | 532/18670 | 0.0000 | 0.0002 | 49 |
GO:0009612 | response to mechanical stimulus | 26/885 | 210/18670 | 0.0000 | 0.0002 | 26 |
GO:0071560 | cellular response to transforming growth factor beta stimulus | 29/885 | 249/18670 | 0.0000 | 0.0002 | 29 |
GO:0072511 | divalent inorganic cation transport | 46/885 | 489/18670 | 0.0000 | 0.0002 | 46 |
GO:0009308 | amine metabolic process | 20/885 | 138/18670 | 0.0000 | 0.0002 | 20 |
GO:1903037 | regulation of leukocyte cell-cell adhesion | 33/885 | 304/18670 | 0.0000 | 0.0002 | 33 |
GO:0048589 | developmental growth | 58/885 | 674/18670 | 0.0000 | 0.0002 | 58 |
GO:0031960 | response to corticosteroid | 22/885 | 162/18670 | 0.0000 | 0.0002 | 22 |
GO:0040017 | positive regulation of locomotion | 53/885 | 598/18670 | 0.0000 | 0.0002 | 53 |
GO:0003006 | developmental process involved in reproduction | 58/885 | 676/18670 | 0.0000 | 0.0002 | 58 |
GO:2000147 | positive regulation of cell motility | 51/885 | 568/18670 | 0.0000 | 0.0002 | 51 |
GO:0006816 | calcium ion transport | 42/885 | 434/18670 | 0.0000 | 0.0002 | 42 |
GO:0033002 | muscle cell proliferation | 28/885 | 239/18670 | 0.0000 | 0.0002 | 28 |
GO:0051272 | positive regulation of cellular component movement | 52/885 | 585/18670 | 0.0000 | 0.0002 | 52 |
GO:0001678 | cellular glucose homeostasis | 21/885 | 152/18670 | 0.0000 | 0.0002 | 21 |
GO:2001020 | regulation of response to DNA damage stimulus | 26/885 | 214/18670 | 0.0000 | 0.0003 | 26 |
GO:0060047 | heart contraction | 31/885 | 280/18670 | 0.0000 | 0.0003 | 31 |
GO:0007221 | positive regulation of transcription of Notch receptor target | 7/885 | 18/18670 | 0.0000 | 0.0003 | 7 |
GO:0044106 | cellular amine metabolic process | 19/885 | 129/18670 | 0.0000 | 0.0003 | 19 |
GO:0050870 | positive regulation of T cell activation | 25/885 | 202/18670 | 0.0000 | 0.0003 | 25 |
GO:0051924 | regulation of calcium ion transport | 29/885 | 254/18670 | 0.0000 | 0.0003 | 29 |
GO:0045859 | regulation of protein kinase activity | 65/885 | 792/18670 | 0.0000 | 0.0003 | 65 |
GO:0048013 | ephrin receptor signaling pathway | 15/885 | 86/18670 | 0.0000 | 0.0003 | 15 |
GO:0071559 | response to transforming growth factor beta | 29/885 | 255/18670 | 0.0000 | 0.0003 | 29 |
GO:0034765 | regulation of ion transmembrane transport | 45/885 | 483/18670 | 0.0000 | 0.0003 | 45 |
GO:1903311 | regulation of mRNA metabolic process | 34/885 | 324/18670 | 0.0000 | 0.0003 | 34 |
GO:0007187 | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | 29/885 | 256/18670 | 0.0000 | 0.0003 | 29 |
GO:0032409 | regulation of transporter activity | 31/885 | 283/18670 | 0.0000 | 0.0003 | 31 |
GO:0051099 | positive regulation of binding | 23/885 | 179/18670 | 0.0000 | 0.0003 | 23 |
GO:0071496 | cellular response to external stimulus | 35/885 | 339/18670 | 0.0000 | 0.0003 | 35 |
GO:0007548 | sex differentiation | 30/885 | 270/18670 | 0.0000 | 0.0003 | 30 |
GO:0000375 | RNA splicing, via transesterification reactions | 38/885 | 382/18670 | 0.0000 | 0.0003 | 38 |
GO:0050727 | regulation of inflammatory response | 45/885 | 485/18670 | 0.0000 | 0.0003 | 45 |
GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 21/885 | 155/18670 | 0.0000 | 0.0003 | 21 |
GO:0072593 | reactive oxygen species metabolic process | 31/885 | 284/18670 | 0.0000 | 0.0003 | 31 |
GO:0070661 | leukocyte proliferation | 32/885 | 298/18670 | 0.0000 | 0.0003 | 32 |
GO:0034612 | response to tumor necrosis factor | 33/885 | 312/18670 | 0.0000 | 0.0003 | 33 |
GO:1905330 | regulation of morphogenesis of an epithelium | 23/885 | 180/18670 | 0.0000 | 0.0003 | 23 |
GO:0050806 | positive regulation of synaptic transmission | 22/885 | 168/18670 | 0.0000 | 0.0003 | 22 |
GO:0042129 | regulation of T cell proliferation | 21/885 | 156/18670 | 0.0000 | 0.0003 | 21 |
GO:0046651 | lymphocyte proliferation | 30/885 | 272/18670 | 0.0000 | 0.0003 | 30 |
GO:1904062 | regulation of cation transmembrane transport | 35/885 | 342/18670 | 0.0000 | 0.0004 | 35 |
GO:0048660 | regulation of smooth muscle cell proliferation | 22/885 | 169/18670 | 0.0000 | 0.0004 | 22 |
GO:0051100 | negative regulation of binding | 22/885 | 169/18670 | 0.0000 | 0.0004 | 22 |
GO:0048872 | homeostasis of number of cells | 28/885 | 246/18670 | 0.0000 | 0.0004 | 28 |
GO:0097755 | positive regulation of blood vessel diameter | 12/885 | 59/18670 | 0.0000 | 0.0004 | 12 |
GO:0070555 | response to interleukin-1 | 25/885 | 207/18670 | 0.0000 | 0.0004 | 25 |
GO:0051480 | regulation of cytosolic calcium ion concentration | 36/885 | 357/18670 | 0.0000 | 0.0004 | 36 |
GO:1901019 | regulation of calcium ion transmembrane transporter activity | 15/885 | 89/18670 | 0.0000 | 0.0004 | 15 |
GO:0030155 | regulation of cell adhesion | 58/885 | 691/18670 | 0.0000 | 0.0004 | 58 |
GO:0032943 | mononuclear cell proliferation | 30/885 | 274/18670 | 0.0000 | 0.0004 | 30 |
GO:0071300 | cellular response to retinoic acid | 13/885 | 69/18670 | 0.0000 | 0.0004 | 13 |
GO:0043433 | negative regulation of DNA-binding transcription factor activity | 22/885 | 170/18670 | 0.0000 | 0.0004 | 22 |
GO:0046683 | response to organophosphorus | 19/885 | 134/18670 | 0.0000 | 0.0004 | 19 |
GO:0051384 | response to glucocorticoid | 20/885 | 146/18670 | 0.0000 | 0.0004 | 20 |
GO:0022407 | regulation of cell-cell adhesion | 39/885 | 403/18670 | 0.0000 | 0.0004 | 39 |
GO:0048659 | smooth muscle cell proliferation | 22/885 | 171/18670 | 0.0000 | 0.0004 | 22 |
GO:0044706 | multi-multicellular organism process | 26/885 | 222/18670 | 0.0000 | 0.0004 | 26 |
GO:0009314 | response to radiation | 42/885 | 448/18670 | 0.0000 | 0.0004 | 42 |
GO:0006352 | DNA-templated transcription, initiation | 28/885 | 249/18670 | 0.0000 | 0.0004 | 28 |
GO:0042098 | T cell proliferation | 23/885 | 184/18670 | 0.0000 | 0.0004 | 23 |
GO:0043401 | steroid hormone mediated signaling pathway | 23/885 | 184/18670 | 0.0000 | 0.0004 | 23 |
GO:0031103 | axon regeneration | 11/885 | 51/18670 | 0.0000 | 0.0004 | 11 |
GO:0071383 | cellular response to steroid hormone stimulus | 28/885 | 250/18670 | 0.0000 | 0.0005 | 28 |
GO:0071356 | cellular response to tumor necrosis factor | 31/885 | 291/18670 | 0.0000 | 0.0005 | 31 |
GO:0071326 | cellular response to monosaccharide stimulus | 19/885 | 136/18670 | 0.0000 | 0.0005 | 19 |
GO:0031669 | cellular response to nutrient levels | 27/885 | 237/18670 | 0.0000 | 0.0005 | 27 |
GO:0015837 | amine transport | 16/885 | 102/18670 | 0.0000 | 0.0005 | 16 |
GO:0031099 | regeneration | 24/885 | 198/18670 | 0.0000 | 0.0005 | 24 |
GO:0016071 | mRNA metabolic process | 69/885 | 877/18670 | 0.0000 | 0.0005 | 69 |
GO:0002026 | regulation of the force of heart contraction | 8/885 | 27/18670 | 0.0000 | 0.0005 | 8 |
GO:0072207 | metanephric epithelium development | 8/885 | 27/18670 | 0.0000 | 0.0005 | 8 |
GO:0098810 | neurotransmitter reuptake | 8/885 | 27/18670 | 0.0000 | 0.0005 | 8 |
GO:0034605 | cellular response to heat | 19/885 | 137/18670 | 0.0000 | 0.0005 | 19 |
GO:0051954 | positive regulation of amine transport | 9/885 | 35/18670 | 0.0000 | 0.0005 | 9 |
GO:1901385 | regulation of voltage-gated calcium channel activity | 9/885 | 35/18670 | 0.0000 | 0.0005 | 9 |
GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 37/885 | 379/18670 | 0.0000 | 0.0005 | 37 |
GO:0000398 | mRNA splicing, via spliceosome | 37/885 | 379/18670 | 0.0000 | 0.0005 | 37 |
GO:1905114 | cell surface receptor signaling pathway involved in cell-cell signaling | 53/885 | 622/18670 | 0.0000 | 0.0005 | 53 |
GO:0030522 | intracellular receptor signaling pathway | 30/885 | 280/18670 | 0.0000 | 0.0005 | 30 |
GO:0035567 | non-canonical Wnt signaling pathway | 20/885 | 150/18670 | 0.0000 | 0.0005 | 20 |
GO:0030048 | actin filament-based movement | 19/885 | 138/18670 | 0.0000 | 0.0005 | 19 |
GO:0048857 | neural nucleus development | 12/885 | 62/18670 | 0.0000 | 0.0005 | 12 |
GO:0032024 | positive regulation of insulin secretion | 13/885 | 72/18670 | 0.0000 | 0.0006 | 13 |
GO:1902036 | regulation of hematopoietic stem cell differentiation | 13/885 | 72/18670 | 0.0000 | 0.0006 | 13 |
GO:0098662 | inorganic cation transmembrane transport | 61/885 | 752/18670 | 0.0000 | 0.0006 | 61 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 23/885 | 188/18670 | 0.0000 | 0.0006 | 23 |
GO:0046822 | regulation of nucleocytoplasmic transport | 16/885 | 104/18670 | 0.0000 | 0.0006 | 16 |
GO:0046928 | regulation of neurotransmitter secretion | 16/885 | 104/18670 | 0.0000 | 0.0006 | 16 |
GO:0097479 | synaptic vesicle localization | 21/885 | 163/18670 | 0.0000 | 0.0006 | 21 |
GO:1902600 | proton transmembrane transport | 21/885 | 163/18670 | 0.0000 | 0.0006 | 21 |
GO:0035270 | endocrine system development | 18/885 | 127/18670 | 0.0000 | 0.0006 | 18 |
GO:0043620 | regulation of DNA-templated transcription in response to stress | 18/885 | 127/18670 | 0.0000 | 0.0006 | 18 |
GO:0050714 | positive regulation of protein secretion | 29/885 | 268/18670 | 0.0000 | 0.0006 | 29 |
GO:1903169 | regulation of calcium ion transmembrane transport | 20/885 | 151/18670 | 0.0000 | 0.0006 | 20 |
GO:0070252 | actin-mediated cell contraction | 17/885 | 116/18670 | 0.0000 | 0.0006 | 17 |
GO:0060218 | hematopoietic stem cell differentiation | 14/885 | 83/18670 | 0.0000 | 0.0006 | 14 |
GO:0048489 | synaptic vesicle transport | 20/885 | 152/18670 | 0.0000 | 0.0006 | 20 |
GO:0097480 | establishment of synaptic vesicle localization | 20/885 | 152/18670 | 0.0000 | 0.0006 | 20 |
GO:0033555 | multicellular organismal response to stress | 13/885 | 73/18670 | 0.0000 | 0.0006 | 13 |
GO:0051338 | regulation of transferase activity | 74/885 | 972/18670 | 0.0000 | 0.0007 | 74 |
GO:0007599 | hemostasis | 34/885 | 341/18670 | 0.0000 | 0.0007 | 34 |
GO:0062012 | regulation of small molecule metabolic process | 42/885 | 459/18670 | 0.0000 | 0.0007 | 42 |
GO:0017157 | regulation of exocytosis | 25/885 | 217/18670 | 0.0000 | 0.0007 | 25 |
GO:0045766 | positive regulation of angiogenesis | 24/885 | 204/18670 | 0.0000 | 0.0007 | 24 |
GO:0051952 | regulation of amine transport | 15/885 | 95/18670 | 0.0000 | 0.0007 | 15 |
GO:0040008 | regulation of growth | 56/885 | 679/18670 | 0.0000 | 0.0007 | 56 |
GO:0008361 | regulation of cell size | 22/885 | 179/18670 | 0.0000 | 0.0007 | 22 |
GO:0071347 | cellular response to interleukin-1 | 22/885 | 179/18670 | 0.0000 | 0.0007 | 22 |
GO:0006913 | nucleocytoplasmic transport | 34/885 | 343/18670 | 0.0000 | 0.0007 | 34 |
GO:0007565 | female pregnancy | 23/885 | 192/18670 | 0.0000 | 0.0007 | 23 |
GO:1901532 | regulation of hematopoietic progenitor cell differentiation | 14/885 | 85/18670 | 0.0000 | 0.0007 | 14 |
GO:1901796 | regulation of signal transduction by p53 class mediator | 22/885 | 180/18670 | 0.0000 | 0.0008 | 22 |
GO:0030879 | mammary gland development | 19/885 | 143/18670 | 0.0000 | 0.0008 | 19 |
GO:0048738 | cardiac muscle tissue development | 26/885 | 233/18670 | 0.0000 | 0.0008 | 26 |
GO:0097305 | response to alcohol | 26/885 | 233/18670 | 0.0000 | 0.0008 | 26 |
GO:0045776 | negative regulation of blood pressure | 10/885 | 46/18670 | 0.0000 | 0.0008 | 10 |
GO:0042110 | T cell activation | 42/885 | 464/18670 | 0.0000 | 0.0008 | 42 |
GO:0050673 | epithelial cell proliferation | 40/885 | 434/18670 | 0.0000 | 0.0008 | 40 |
GO:0032526 | response to retinoic acid | 16/885 | 108/18670 | 0.0000 | 0.0008 | 16 |
GO:0099565 | chemical synaptic transmission, postsynaptic | 16/885 | 108/18670 | 0.0000 | 0.0008 | 16 |
GO:0006091 | generation of precursor metabolites and energy | 46/885 | 526/18670 | 0.0000 | 0.0008 | 46 |
GO:0099504 | synaptic vesicle cycle | 23/885 | 194/18670 | 0.0000 | 0.0008 | 23 |
GO:0051169 | nuclear transport | 34/885 | 346/18670 | 0.0000 | 0.0008 | 34 |
GO:0051591 | response to cAMP | 15/885 | 97/18670 | 0.0000 | 0.0008 | 15 |
GO:0010332 | response to gamma radiation | 11/885 | 56/18670 | 0.0001 | 0.0009 | 11 |
GO:0030335 | positive regulation of cell migration | 47/885 | 544/18670 | 0.0001 | 0.0009 | 47 |
GO:0051590 | positive regulation of neurotransmitter transport | 9/885 | 38/18670 | 0.0001 | 0.0009 | 9 |
GO:1901342 | regulation of vasculature development | 39/885 | 422/18670 | 0.0001 | 0.0009 | 39 |
GO:0043618 | regulation of transcription from RNA polymerase II promoter in response to stress | 17/885 | 121/18670 | 0.0001 | 0.0009 | 17 |
GO:0071333 | cellular response to glucose stimulus | 18/885 | 133/18670 | 0.0001 | 0.0009 | 18 |
GO:0045664 | regulation of neuron differentiation | 54/885 | 656/18670 | 0.0001 | 0.0009 | 54 |
GO:0050678 | regulation of epithelial cell proliferation | 36/885 | 378/18670 | 0.0001 | 0.0009 | 36 |
GO:0060284 | regulation of cell development | 72/885 | 953/18670 | 0.0001 | 0.0010 | 72 |
GO:0043410 | positive regulation of MAPK cascade | 47/885 | 546/18670 | 0.0001 | 0.0010 | 47 |
GO:0008380 | RNA splicing | 42/885 | 469/18670 | 0.0001 | 0.0010 | 42 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 13/885 | 77/18670 | 0.0001 | 0.0010 | 13 |
GO:0032355 | response to estradiol | 18/885 | 134/18670 | 0.0001 | 0.0010 | 18 |
GO:0007596 | blood coagulation | 33/885 | 336/18670 | 0.0001 | 0.0010 | 33 |
GO:0002764 | immune response-regulating signaling pathway | 55/885 | 675/18670 | 0.0001 | 0.0010 | 55 |
GO:0007517 | muscle organ development | 38/885 | 410/18670 | 0.0001 | 0.0010 | 38 |
GO:0072215 | regulation of metanephros development | 7/885 | 23/18670 | 0.0001 | 0.0010 | 7 |
GO:0072243 | metanephric nephron epithelium development | 7/885 | 23/18670 | 0.0001 | 0.0010 | 7 |
GO:0051129 | negative regulation of cellular component organization | 59/885 | 741/18670 | 0.0001 | 0.0011 | 59 |
GO:0071331 | cellular response to hexose stimulus | 18/885 | 135/18670 | 0.0001 | 0.0011 | 18 |
GO:0060079 | excitatory postsynaptic potential | 15/885 | 100/18670 | 0.0001 | 0.0011 | 15 |
GO:1902041 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | 11/885 | 58/18670 | 0.0001 | 0.0012 | 11 |
GO:0045765 | regulation of angiogenesis | 36/885 | 383/18670 | 0.0001 | 0.0012 | 36 |
GO:0001503 | ossification | 37/885 | 398/18670 | 0.0001 | 0.0012 | 37 |
GO:0031668 | cellular response to extracellular stimulus | 28/885 | 268/18670 | 0.0001 | 0.0012 | 28 |
GO:0019933 | cAMP-mediated signaling | 22/885 | 187/18670 | 0.0001 | 0.0012 | 22 |
GO:0010720 | positive regulation of cell development | 47/885 | 553/18670 | 0.0001 | 0.0013 | 47 |
GO:0080135 | regulation of cellular response to stress | 59/885 | 746/18670 | 0.0001 | 0.0013 | 59 |
GO:0014074 | response to purine-containing compound | 19/885 | 149/18670 | 0.0001 | 0.0013 | 19 |
GO:0046007 | negative regulation of activated T cell proliferation | 5/885 | 11/18670 | 0.0001 | 0.0013 | 5 |
GO:0030163 | protein catabolic process | 70/885 | 931/18670 | 0.0001 | 0.0013 | 70 |
GO:0031102 | neuron projection regeneration | 11/885 | 59/18670 | 0.0001 | 0.0013 | 11 |
GO:0032388 | positive regulation of intracellular transport | 24/885 | 215/18670 | 0.0001 | 0.0014 | 24 |
GO:0050817 | coagulation | 33/885 | 342/18670 | 0.0001 | 0.0014 | 33 |
GO:0071295 | cellular response to vitamin | 8/885 | 32/18670 | 0.0001 | 0.0014 | 8 |
GO:0015980 | energy derivation by oxidation of organic compounds | 29/885 | 285/18670 | 0.0001 | 0.0014 | 29 |
GO:0050863 | regulation of T cell activation | 31/885 | 314/18670 | 0.0001 | 0.0014 | 31 |
GO:0001819 | positive regulation of cytokine production | 41/885 | 464/18670 | 0.0001 | 0.0015 | 41 |
GO:1904018 | positive regulation of vasculature development | 25/885 | 230/18670 | 0.0001 | 0.0015 | 25 |
GO:0043488 | regulation of mRNA stability | 21/885 | 177/18670 | 0.0001 | 0.0015 | 21 |
GO:0007189 | adenylate cyclase-activating G protein-coupled receptor signaling pathway | 18/885 | 139/18670 | 0.0001 | 0.0015 | 18 |
GO:0018149 | peptide cross-linking | 11/885 | 60/18670 | 0.0001 | 0.0015 | 11 |
GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 15/885 | 104/18670 | 0.0001 | 0.0017 | 15 |
GO:0043254 | regulation of protein complex assembly | 41/885 | 467/18670 | 0.0001 | 0.0017 | 41 |
GO:0002757 | immune response-activating signal transduction | 52/885 | 641/18670 | 0.0001 | 0.0017 | 52 |
GO:0032412 | regulation of ion transmembrane transporter activity | 27/885 | 260/18670 | 0.0001 | 0.0017 | 27 |
GO:0098609 | cell-cell adhesion | 64/885 | 839/18670 | 0.0001 | 0.0017 | 64 |
GO:0060249 | anatomical structure homeostasis | 39/885 | 437/18670 | 0.0001 | 0.0017 | 39 |
GO:0007589 | body fluid secretion | 14/885 | 93/18670 | 0.0001 | 0.0017 | 14 |
GO:0072202 | cell differentiation involved in metanephros development | 7/885 | 25/18670 | 0.0001 | 0.0017 | 7 |
GO:0010035 | response to inorganic substance | 47/885 | 562/18670 | 0.0001 | 0.0017 | 47 |
GO:0007584 | response to nutrient | 24/885 | 219/18670 | 0.0001 | 0.0017 | 24 |
GO:0007610 | behavior | 49/885 | 594/18670 | 0.0001 | 0.0017 | 49 |
GO:0070997 | neuron death | 33/885 | 348/18670 | 0.0001 | 0.0018 | 33 |
GO:0097094 | craniofacial suture morphogenesis | 6/885 | 18/18670 | 0.0001 | 0.0018 | 6 |
GO:0033209 | tumor necrosis factor-mediated signaling pathway | 20/885 | 167/18670 | 0.0001 | 0.0019 | 20 |
GO:0050805 | negative regulation of synaptic transmission | 12/885 | 72/18670 | 0.0001 | 0.0019 | 12 |
GO:0051168 | nuclear export | 22/885 | 194/18670 | 0.0001 | 0.0020 | 22 |
GO:0050671 | positive regulation of lymphocyte proliferation | 17/885 | 130/18670 | 0.0001 | 0.0020 | 17 |
GO:0045926 | negative regulation of growth | 26/885 | 249/18670 | 0.0001 | 0.0020 | 26 |
GO:0001906 | cell killing | 20/885 | 168/18670 | 0.0001 | 0.0020 | 20 |
GO:0002260 | lymphocyte homeostasis | 11/885 | 62/18670 | 0.0001 | 0.0020 | 11 |
GO:0006521 | regulation of cellular amino acid metabolic process | 11/885 | 62/18670 | 0.0001 | 0.0020 | 11 |
GO:0007623 | circadian rhythm | 23/885 | 208/18670 | 0.0001 | 0.0020 | 23 |
GO:0002444 | myeloid leukocyte mediated immunity | 46/885 | 551/18670 | 0.0001 | 0.0020 | 46 |
GO:0043516 | regulation of DNA damage response, signal transduction by p53 class mediator | 8/885 | 34/18670 | 0.0001 | 0.0021 | 8 |
GO:0008217 | regulation of blood pressure | 21/885 | 182/18670 | 0.0002 | 0.0021 | 21 |
GO:0019884 | antigen processing and presentation of exogenous antigen | 21/885 | 182/18670 | 0.0002 | 0.0021 | 21 |
GO:1903524 | positive regulation of blood circulation | 12/885 | 73/18670 | 0.0002 | 0.0021 | 12 |
GO:0032946 | positive regulation of mononuclear cell proliferation | 17/885 | 131/18670 | 0.0002 | 0.0021 | 17 |
GO:0071377 | cellular response to glucagon stimulus | 7/885 | 26/18670 | 0.0002 | 0.0022 | 7 |
GO:0043487 | regulation of RNA stability | 21/885 | 183/18670 | 0.0002 | 0.0023 | 21 |
GO:0048598 | embryonic morphogenesis | 48/885 | 586/18670 | 0.0002 | 0.0023 | 48 |
GO:0097191 | extrinsic apoptotic signaling pathway | 24/885 | 224/18670 | 0.0002 | 0.0023 | 24 |
GO:1903829 | positive regulation of cellular protein localization | 31/885 | 324/18670 | 0.0002 | 0.0023 | 31 |
GO:0030100 | regulation of endocytosis | 28/885 | 281/18670 | 0.0002 | 0.0024 | 28 |
GO:0006119 | oxidative phosphorylation | 18/885 | 145/18670 | 0.0002 | 0.0024 | 18 |
GO:2000696 | regulation of epithelial cell differentiation involved in kidney development | 6/885 | 19/18670 | 0.0002 | 0.0024 | 6 |
GO:1903827 | regulation of cellular protein localization | 44/885 | 524/18670 | 0.0002 | 0.0024 | 44 |
GO:0043408 | regulation of MAPK cascade | 59/885 | 768/18670 | 0.0002 | 0.0024 | 59 |
GO:0031348 | negative regulation of defense response | 25/885 | 239/18670 | 0.0002 | 0.0025 | 25 |
GO:0035850 | epithelial cell differentiation involved in kidney development | 9/885 | 44/18670 | 0.0002 | 0.0025 | 9 |
GO:0046688 | response to copper ion | 9/885 | 44/18670 | 0.0002 | 0.0025 | 9 |
GO:0001508 | action potential | 17/885 | 133/18670 | 0.0002 | 0.0025 | 17 |
GO:0006397 | mRNA processing | 45/885 | 541/18670 | 0.0002 | 0.0025 | 45 |
GO:0006897 | endocytosis | 62/885 | 820/18670 | 0.0002 | 0.0025 | 62 |
GO:1903708 | positive regulation of hemopoiesis | 21/885 | 185/18670 | 0.0002 | 0.0025 | 21 |
GO:0045666 | positive regulation of neuron differentiation | 34/885 | 371/18670 | 0.0002 | 0.0026 | 34 |
GO:0061005 | cell differentiation involved in kidney development | 10/885 | 54/18670 | 0.0002 | 0.0026 | 10 |
GO:0007179 | transforming growth factor beta receptor signaling pathway | 22/885 | 199/18670 | 0.0002 | 0.0026 | 22 |
GO:0061061 | muscle structure development | 53/885 | 672/18670 | 0.0002 | 0.0026 | 53 |
GO:0006163 | purine nucleotide metabolic process | 47/885 | 575/18670 | 0.0002 | 0.0027 | 47 |
GO:0050767 | regulation of neurogenesis | 62/885 | 822/18670 | 0.0002 | 0.0027 | 62 |
GO:1901214 | regulation of neuron death | 30/885 | 313/18670 | 0.0002 | 0.0027 | 30 |
GO:0002275 | myeloid cell activation involved in immune response | 45/885 | 544/18670 | 0.0002 | 0.0028 | 45 |
GO:1903305 | regulation of regulated secretory pathway | 19/885 | 160/18670 | 0.0002 | 0.0028 | 19 |
GO:0006939 | smooth muscle contraction | 15/885 | 110/18670 | 0.0002 | 0.0028 | 15 |
GO:0098739 | import across plasma membrane | 15/885 | 110/18670 | 0.0002 | 0.0028 | 15 |
GO:0014823 | response to activity | 11/885 | 65/18670 | 0.0002 | 0.0028 | 11 |
GO:1905475 | regulation of protein localization to membrane | 21/885 | 187/18670 | 0.0002 | 0.0028 | 21 |
GO:0060123 | regulation of growth hormone secretion | 5/885 | 13/18670 | 0.0002 | 0.0028 | 5 |
GO:0072182 | regulation of nephron tubule epithelial cell differentiation | 5/885 | 13/18670 | 0.0002 | 0.0028 | 5 |
GO:1900272 | negative regulation of long-term synaptic potentiation | 5/885 | 13/18670 | 0.0002 | 0.0028 | 5 |
GO:0033762 | response to glucagon | 8/885 | 36/18670 | 0.0002 | 0.0029 | 8 |
GO:0060428 | lung epithelium development | 8/885 | 36/18670 | 0.0002 | 0.0029 | 8 |
GO:0019395 | fatty acid oxidation | 14/885 | 99/18670 | 0.0002 | 0.0030 | 14 |
GO:0019935 | cyclic-nucleotide-mediated signaling | 23/885 | 215/18670 | 0.0002 | 0.0030 | 23 |
GO:0010975 | regulation of neuron projection development | 42/885 | 499/18670 | 0.0002 | 0.0030 | 42 |
GO:0002478 | antigen processing and presentation of exogenous peptide antigen | 20/885 | 175/18670 | 0.0002 | 0.0031 | 20 |
GO:0048644 | muscle organ morphogenesis | 13/885 | 88/18670 | 0.0002 | 0.0031 | 13 |
GO:0001736 | establishment of planar polarity | 16/885 | 124/18670 | 0.0003 | 0.0032 | 16 |
GO:0007164 | establishment of tissue polarity | 16/885 | 124/18670 | 0.0003 | 0.0032 | 16 |
GO:0048002 | antigen processing and presentation of peptide antigen | 21/885 | 189/18670 | 0.0003 | 0.0032 | 21 |
GO:0003180 | aortic valve morphogenesis | 7/885 | 28/18670 | 0.0003 | 0.0032 | 7 |
GO:0017158 | regulation of calcium ion-dependent exocytosis | 15/885 | 112/18670 | 0.0003 | 0.0032 | 15 |
GO:0070268 | cornification | 15/885 | 112/18670 | 0.0003 | 0.0032 | 15 |
GO:0048638 | regulation of developmental growth | 32/885 | 347/18670 | 0.0003 | 0.0033 | 32 |
GO:0001504 | neurotransmitter uptake | 9/885 | 46/18670 | 0.0003 | 0.0033 | 9 |
GO:0060537 | muscle tissue development | 36/885 | 408/18670 | 0.0003 | 0.0033 | 36 |
GO:0032615 | interleukin-12 production | 10/885 | 56/18670 | 0.0003 | 0.0033 | 10 |
GO:0098586 | cellular response to virus | 10/885 | 56/18670 | 0.0003 | 0.0033 | 10 |
GO:0043299 | leukocyte degranulation | 44/885 | 534/18670 | 0.0003 | 0.0033 | 44 |
GO:0030162 | regulation of proteolysis | 62/885 | 831/18670 | 0.0003 | 0.0033 | 62 |
GO:0018108 | peptidyl-tyrosine phosphorylation | 33/885 | 363/18670 | 0.0003 | 0.0034 | 33 |
GO:0016042 | lipid catabolic process | 31/885 | 333/18670 | 0.0003 | 0.0034 | 31 |
GO:0032147 | activation of protein kinase activity | 31/885 | 333/18670 | 0.0003 | 0.0034 | 31 |
GO:0046006 | regulation of activated T cell proliferation | 8/885 | 37/18670 | 0.0003 | 0.0034 | 8 |
GO:0035265 | organ growth | 22/885 | 204/18670 | 0.0003 | 0.0034 | 22 |
GO:0002027 | regulation of heart rate | 14/885 | 101/18670 | 0.0003 | 0.0035 | 14 |
GO:0034440 | lipid oxidation | 14/885 | 101/18670 | 0.0003 | 0.0035 | 14 |
GO:0097006 | regulation of plasma lipoprotein particle levels | 14/885 | 101/18670 | 0.0003 | 0.0035 | 14 |
GO:0010038 | response to metal ion | 33/885 | 364/18670 | 0.0003 | 0.0035 | 33 |
GO:0007204 | positive regulation of cytosolic calcium ion concentration | 30/885 | 319/18670 | 0.0003 | 0.0035 | 30 |
GO:0007178 | transmembrane receptor protein serine/threonine kinase signaling pathway | 32/885 | 349/18670 | 0.0003 | 0.0035 | 32 |
GO:0046649 | lymphocyte activation | 56/885 | 733/18670 | 0.0003 | 0.0036 | 56 |
GO:0002696 | positive regulation of leukocyte activation | 34/885 | 380/18670 | 0.0003 | 0.0036 | 34 |
GO:0009205 | purine ribonucleoside triphosphate metabolic process | 31/885 | 335/18670 | 0.0003 | 0.0037 | 31 |
GO:0015844 | monoamine transport | 13/885 | 90/18670 | 0.0003 | 0.0037 | 13 |
GO:0030901 | midbrain development | 13/885 | 90/18670 | 0.0003 | 0.0037 | 13 |
GO:0050769 | positive regulation of neurogenesis | 40/885 | 474/18670 | 0.0003 | 0.0037 | 40 |
GO:0031333 | negative regulation of protein complex assembly | 17/885 | 139/18670 | 0.0003 | 0.0037 | 17 |
GO:0070665 | positive regulation of leukocyte proliferation | 17/885 | 139/18670 | 0.0003 | 0.0037 | 17 |
GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 42/885 | 506/18670 | 0.0003 | 0.0037 | 42 |
GO:0018212 | peptidyl-tyrosine modification | 33/885 | 366/18670 | 0.0003 | 0.0038 | 33 |
GO:0002438 | acute inflammatory response to antigenic stimulus | 6/885 | 21/18670 | 0.0003 | 0.0038 | 6 |
GO:0014821 | phasic smooth muscle contraction | 6/885 | 21/18670 | 0.0003 | 0.0038 | 6 |
GO:0006611 | protein export from nucleus | 20/885 | 179/18670 | 0.0003 | 0.0039 | 20 |
GO:0060452 | positive regulation of cardiac muscle contraction | 5/885 | 14/18670 | 0.0003 | 0.0039 | 5 |
GO:0060562 | epithelial tube morphogenesis | 30/885 | 322/18670 | 0.0003 | 0.0039 | 30 |
GO:0016572 | histone phosphorylation | 8/885 | 38/18670 | 0.0003 | 0.0039 | 8 |
GO:0046825 | regulation of protein export from nucleus | 8/885 | 38/18670 | 0.0003 | 0.0039 | 8 |
GO:0072073 | kidney epithelium development | 17/885 | 140/18670 | 0.0003 | 0.0040 | 17 |
GO:0060485 | mesenchyme development | 27/885 | 278/18670 | 0.0003 | 0.0040 | 27 |
GO:0002064 | epithelial cell development | 22/885 | 207/18670 | 0.0003 | 0.0040 | 22 |
GO:0035690 | cellular response to drug | 33/885 | 369/18670 | 0.0004 | 0.0043 | 33 |
GO:0009161 | ribonucleoside monophosphate metabolic process | 32/885 | 354/18670 | 0.0004 | 0.0043 | 32 |
GO:0055008 | cardiac muscle tissue morphogenesis | 11/885 | 69/18670 | 0.0004 | 0.0043 | 11 |
GO:0051960 | regulation of nervous system development | 67/885 | 927/18670 | 0.0004 | 0.0043 | 67 |
GO:0002683 | negative regulation of immune system process | 39/885 | 463/18670 | 0.0004 | 0.0044 | 39 |
GO:0032535 | regulation of cellular component size | 33/885 | 370/18670 | 0.0004 | 0.0044 | 33 |
GO:0009167 | purine ribonucleoside monophosphate metabolic process | 31/885 | 340/18670 | 0.0004 | 0.0045 | 31 |
GO:0061138 | morphogenesis of a branching epithelium | 20/885 | 182/18670 | 0.0004 | 0.0047 | 20 |
GO:0009126 | purine nucleoside monophosphate metabolic process | 31/885 | 341/18670 | 0.0004 | 0.0047 | 31 |
GO:0009199 | ribonucleoside triphosphate metabolic process | 31/885 | 341/18670 | 0.0004 | 0.0047 | 31 |
GO:0009615 | response to virus | 30/885 | 326/18670 | 0.0004 | 0.0047 | 30 |
GO:0030258 | lipid modification | 24/885 | 238/18670 | 0.0004 | 0.0047 | 24 |
GO:0097529 | myeloid leukocyte migration | 22/885 | 210/18670 | 0.0004 | 0.0048 | 22 |
GO:0051966 | regulation of synaptic transmission, glutamatergic | 11/885 | 70/18670 | 0.0004 | 0.0048 | 11 |
GO:0007269 | neurotransmitter secretion | 19/885 | 169/18670 | 0.0004 | 0.0048 | 19 |
GO:0050728 | negative regulation of inflammatory response | 19/885 | 169/18670 | 0.0004 | 0.0048 | 19 |
GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle | 13/885 | 93/18670 | 0.0004 | 0.0048 | 13 |
GO:0035249 | synaptic transmission, glutamatergic | 13/885 | 93/18670 | 0.0004 | 0.0048 | 13 |
GO:0055017 | cardiac muscle tissue growth | 14/885 | 105/18670 | 0.0004 | 0.0048 | 14 |
GO:1902750 | negative regulation of cell cycle G2/M phase transition | 14/885 | 105/18670 | 0.0004 | 0.0048 | 14 |
GO:0009144 | purine nucleoside triphosphate metabolic process | 31/885 | 342/18670 | 0.0004 | 0.0048 | 31 |
GO:0030856 | regulation of epithelial cell differentiation | 18/885 | 156/18670 | 0.0004 | 0.0048 | 18 |
GO:0034767 | positive regulation of ion transmembrane transport | 18/885 | 156/18670 | 0.0004 | 0.0048 | 18 |
GO:0010506 | regulation of autophagy | 30/885 | 327/18670 | 0.0004 | 0.0048 | 30 |
GO:0033157 | regulation of intracellular protein transport | 23/885 | 225/18670 | 0.0005 | 0.0050 | 23 |
GO:0099643 | signal release from synapse | 19/885 | 170/18670 | 0.0005 | 0.0051 | 19 |
GO:0072521 | purine-containing compound metabolic process | 48/885 | 613/18670 | 0.0005 | 0.0051 | 48 |
GO:0060415 | muscle tissue morphogenesis | 12/885 | 82/18670 | 0.0005 | 0.0051 | 12 |
GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator | 5/885 | 15/18670 | 0.0005 | 0.0052 | 5 |
GO:0072160 | nephron tubule epithelial cell differentiation | 5/885 | 15/18670 | 0.0005 | 0.0052 | 5 |
GO:1904064 | positive regulation of cation transmembrane transport | 17/885 | 144/18670 | 0.0005 | 0.0052 | 17 |
GO:0019882 | antigen processing and presentation | 23/885 | 226/18670 | 0.0005 | 0.0052 | 23 |
GO:0014706 | striated muscle tissue development | 34/885 | 390/18670 | 0.0005 | 0.0052 | 34 |
GO:0009416 | response to light stimulus | 29/885 | 314/18670 | 0.0005 | 0.0053 | 29 |
GO:0009268 | response to pH | 8/885 | 40/18670 | 0.0005 | 0.0053 | 8 |
GO:0045823 | positive regulation of heart contraction | 8/885 | 40/18670 | 0.0005 | 0.0053 | 8 |
GO:0050832 | defense response to fungus | 8/885 | 40/18670 | 0.0005 | 0.0053 | 8 |
GO:0060401 | cytosolic calcium ion transport | 19/885 | 171/18670 | 0.0005 | 0.0053 | 19 |
GO:0043062 | extracellular structure organization | 36/885 | 422/18670 | 0.0005 | 0.0054 | 36 |
GO:0045165 | cell fate commitment | 26/885 | 270/18670 | 0.0005 | 0.0054 | 26 |
GO:0038093 | Fc receptor signaling pathway | 24/885 | 241/18670 | 0.0005 | 0.0054 | 24 |
GO:0016079 | synaptic vesicle exocytosis | 15/885 | 119/18670 | 0.0005 | 0.0054 | 15 |
GO:0060292 | long-term synaptic depression | 7/885 | 31/18670 | 0.0005 | 0.0054 | 7 |
GO:0090075 | relaxation of muscle | 7/885 | 31/18670 | 0.0005 | 0.0054 | 7 |
GO:0007369 | gastrulation | 20/885 | 185/18670 | 0.0005 | 0.0054 | 20 |
GO:0060402 | calcium ion transport into cytosol | 18/885 | 158/18670 | 0.0005 | 0.0054 | 18 |
GO:0061013 | regulation of mRNA catabolic process | 21/885 | 199/18670 | 0.0005 | 0.0054 | 21 |
GO:0030518 | intracellular steroid hormone receptor signaling pathway | 16/885 | 132/18670 | 0.0005 | 0.0055 | 16 |
GO:0001909 | leukocyte mediated cytotoxicity | 14/885 | 107/18670 | 0.0005 | 0.0055 | 14 |
GO:0042102 | positive regulation of T cell proliferation | 13/885 | 95/18670 | 0.0005 | 0.0056 | 13 |
GO:0050851 | antigen receptor-mediated signaling pathway | 29/885 | 316/18670 | 0.0005 | 0.0057 | 29 |
GO:0006635 | fatty acid beta-oxidation | 11/885 | 72/18670 | 0.0005 | 0.0057 | 11 |
GO:0002274 | myeloid leukocyte activation | 50/885 | 651/18670 | 0.0005 | 0.0058 | 50 |
GO:0006974 | cellular response to DNA damage stimulus | 62/885 | 854/18670 | 0.0006 | 0.0058 | 62 |
GO:0002283 | neutrophil activation involved in immune response | 40/885 | 488/18670 | 0.0006 | 0.0058 | 40 |
GO:0010499 | proteasomal ubiquitin-independent protein catabolic process | 6/885 | 23/18670 | 0.0006 | 0.0058 | 6 |
GO:0072170 | metanephric tubule development | 6/885 | 23/18670 | 0.0006 | 0.0058 | 6 |
GO:2000637 | positive regulation of gene silencing by miRNA | 6/885 | 23/18670 | 0.0006 | 0.0058 | 6 |
GO:0031349 | positive regulation of defense response | 42/885 | 521/18670 | 0.0006 | 0.0060 | 42 |
GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 14/885 | 108/18670 | 0.0006 | 0.0060 | 14 |
GO:0050867 | positive regulation of cell activation | 34/885 | 394/18670 | 0.0006 | 0.0060 | 34 |
GO:0002429 | immune response-activating cell surface receptor signaling pathway | 39/885 | 473/18670 | 0.0006 | 0.0060 | 39 |
GO:0048167 | regulation of synaptic plasticity | 20/885 | 187/18670 | 0.0006 | 0.0060 | 20 |
GO:0050798 | activated T cell proliferation | 8/885 | 41/18670 | 0.0006 | 0.0060 | 8 |
GO:0002262 | myeloid cell homeostasis | 17/885 | 147/18670 | 0.0006 | 0.0062 | 17 |
GO:0010212 | response to ionizing radiation | 17/885 | 147/18670 | 0.0006 | 0.0062 | 17 |
GO:0007006 | mitochondrial membrane organization | 16/885 | 134/18670 | 0.0006 | 0.0062 | 16 |
GO:0045596 | negative regulation of cell differentiation | 56/885 | 755/18670 | 0.0006 | 0.0062 | 56 |
GO:0003007 | heart morphogenesis | 25/885 | 259/18670 | 0.0006 | 0.0062 | 25 |
GO:0003208 | cardiac ventricle morphogenesis | 11/885 | 73/18670 | 0.0006 | 0.0062 | 11 |
GO:0097435 | supramolecular fiber organization | 51/885 | 671/18670 | 0.0006 | 0.0062 | 51 |
GO:0046824 | positive regulation of nucleocytoplasmic transport | 10/885 | 62/18670 | 0.0006 | 0.0063 | 10 |
GO:0051251 | positive regulation of lymphocyte activation | 30/885 | 334/18670 | 0.0006 | 0.0063 | 30 |
GO:0003176 | aortic valve development | 7/885 | 32/18670 | 0.0006 | 0.0063 | 7 |
GO:0042311 | vasodilation | 7/885 | 32/18670 | 0.0006 | 0.0063 | 7 |
GO:0044257 | cellular protein catabolic process | 57/885 | 773/18670 | 0.0006 | 0.0064 | 57 |
GO:0032102 | negative regulation of response to external stimulus | 32/885 | 365/18670 | 0.0006 | 0.0064 | 32 |
GO:2001022 | positive regulation of response to DNA damage stimulus | 13/885 | 97/18670 | 0.0007 | 0.0065 | 13 |
GO:0044242 | cellular lipid catabolic process | 22/885 | 217/18670 | 0.0007 | 0.0066 | 22 |
GO:0030252 | growth hormone secretion | 5/885 | 16/18670 | 0.0007 | 0.0066 | 5 |
GO:0045989 | positive regulation of striated muscle contraction | 5/885 | 16/18670 | 0.0007 | 0.0066 | 5 |
GO:0071871 | response to epinephrine | 5/885 | 16/18670 | 0.0007 | 0.0066 | 5 |
GO:0002366 | leukocyte activation involved in immune response | 53/885 | 707/18670 | 0.0007 | 0.0066 | 53 |
GO:0009620 | response to fungus | 9/885 | 52/18670 | 0.0007 | 0.0067 | 9 |
GO:2000677 | regulation of transcription regulatory region DNA binding | 9/885 | 52/18670 | 0.0007 | 0.0067 | 9 |
GO:0009150 | purine ribonucleotide metabolic process | 43/885 | 542/18670 | 0.0007 | 0.0068 | 43 |
GO:0042445 | hormone metabolic process | 23/885 | 232/18670 | 0.0007 | 0.0068 | 23 |
GO:0031670 | cellular response to nutrient | 11/885 | 74/18670 | 0.0007 | 0.0068 | 11 |
GO:0090175 | regulation of establishment of planar polarity | 14/885 | 110/18670 | 0.0007 | 0.0068 | 14 |
GO:0010001 | glial cell differentiation | 22/885 | 218/18670 | 0.0007 | 0.0069 | 22 |
GO:0009117 | nucleotide metabolic process | 53/885 | 709/18670 | 0.0007 | 0.0070 | 53 |
GO:0035637 | multicellular organismal signaling | 21/885 | 204/18670 | 0.0007 | 0.0070 | 21 |
GO:0051928 | positive regulation of calcium ion transport | 15/885 | 123/18670 | 0.0007 | 0.0070 | 15 |
GO:0060148 | positive regulation of posttranscriptional gene silencing | 6/885 | 24/18670 | 0.0007 | 0.0070 | 6 |
GO:0001776 | leukocyte homeostasis | 12/885 | 86/18670 | 0.0007 | 0.0070 | 12 |
GO:0008625 | extrinsic apoptotic signaling pathway via death domain receptors | 12/885 | 86/18670 | 0.0007 | 0.0070 | 12 |
GO:0090559 | regulation of membrane permeability | 12/885 | 86/18670 | 0.0007 | 0.0070 | 12 |
GO:0031214 | biomineral tissue development | 18/885 | 163/18670 | 0.0007 | 0.0072 | 18 |
GO:0019693 | ribose phosphate metabolic process | 45/885 | 577/18670 | 0.0007 | 0.0072 | 45 |
GO:0002263 | cell activation involved in immune response | 53/885 | 711/18670 | 0.0008 | 0.0073 | 53 |
GO:0010737 | protein kinase A signaling | 7/885 | 33/18670 | 0.0008 | 0.0073 | 7 |
GO:0033028 | myeloid cell apoptotic process | 7/885 | 33/18670 | 0.0008 | 0.0073 | 7 |
GO:0099084 | postsynaptic specialization organization | 7/885 | 33/18670 | 0.0008 | 0.0073 | 7 |
GO:0030099 | myeloid cell differentiation | 35/885 | 416/18670 | 0.0008 | 0.0073 | 35 |
GO:0008544 | epidermis development | 38/885 | 464/18670 | 0.0008 | 0.0074 | 38 |
GO:0009895 | negative regulation of catabolic process | 28/885 | 308/18670 | 0.0008 | 0.0074 | 28 |
GO:0048588 | developmental cell growth | 23/885 | 234/18670 | 0.0008 | 0.0074 | 23 |
GO:0050679 | positive regulation of epithelial cell proliferation | 21/885 | 206/18670 | 0.0008 | 0.0077 | 21 |
GO:0044087 | regulation of cellular component biogenesis | 67/885 | 954/18670 | 0.0008 | 0.0077 | 67 |
GO:0021762 | substantia nigra development | 8/885 | 43/18670 | 0.0008 | 0.0077 | 8 |
GO:0034383 | low-density lipoprotein particle clearance | 8/885 | 43/18670 | 0.0008 | 0.0077 | 8 |
GO:1904646 | cellular response to amyloid-beta | 8/885 | 43/18670 | 0.0008 | 0.0077 | 8 |
GO:0046777 | protein autophosphorylation | 23/885 | 235/18670 | 0.0008 | 0.0078 | 23 |
GO:0042119 | neutrophil activation | 40/885 | 498/18670 | 0.0008 | 0.0078 | 40 |
GO:0060419 | heart growth | 14/885 | 112/18670 | 0.0008 | 0.0079 | 14 |
GO:0030432 | peristalsis | 4/885 | 10/18670 | 0.0008 | 0.0079 | 4 |
GO:0070091 | glucagon secretion | 4/885 | 10/18670 | 0.0008 | 0.0079 | 4 |
GO:0002446 | neutrophil mediated immunity | 40/885 | 499/18670 | 0.0009 | 0.0080 | 40 |
GO:0045333 | cellular respiration | 20/885 | 193/18670 | 0.0009 | 0.0081 | 20 |
GO:0007200 | phospholipase C-activating G protein-coupled receptor signaling pathway | 13/885 | 100/18670 | 0.0009 | 0.0081 | 13 |
GO:2001023 | regulation of response to drug | 13/885 | 100/18670 | 0.0009 | 0.0081 | 13 |
GO:0006753 | nucleoside phosphate metabolic process | 53/885 | 716/18670 | 0.0009 | 0.0083 | 53 |
GO:0016049 | cell growth | 39/885 | 484/18670 | 0.0009 | 0.0084 | 39 |
GO:0032655 | regulation of interleukin-12 production | 9/885 | 54/18670 | 0.0009 | 0.0084 | 9 |
GO:0070206 | protein trimerization | 9/885 | 54/18670 | 0.0009 | 0.0084 | 9 |
GO:1904645 | response to amyloid-beta | 9/885 | 54/18670 | 0.0009 | 0.0084 | 9 |
GO:0045088 | regulation of innate immune response | 37/885 | 452/18670 | 0.0009 | 0.0084 | 37 |
GO:0010976 | positive regulation of neuron projection development | 26/885 | 281/18670 | 0.0009 | 0.0084 | 26 |
GO:0090185 | negative regulation of kidney development | 5/885 | 17/18670 | 0.0009 | 0.0084 | 5 |
GO:0043200 | response to amino acid | 14/885 | 113/18670 | 0.0009 | 0.0084 | 14 |
GO:0048640 | negative regulation of developmental growth | 14/885 | 113/18670 | 0.0009 | 0.0084 | 14 |
GO:0002244 | hematopoietic progenitor cell differentiation | 18/885 | 166/18670 | 0.0009 | 0.0084 | 18 |
GO:1901215 | negative regulation of neuron death | 21/885 | 208/18670 | 0.0009 | 0.0084 | 21 |
GO:0032479 | regulation of type I interferon production | 15/885 | 126/18670 | 0.0009 | 0.0084 | 15 |
GO:0071346 | cellular response to interferon-gamma | 19/885 | 180/18670 | 0.0009 | 0.0085 | 19 |
GO:0043312 | neutrophil degranulation | 39/885 | 485/18670 | 0.0009 | 0.0085 | 39 |
GO:0051249 | regulation of lymphocyte activation | 39/885 | 485/18670 | 0.0009 | 0.0085 | 39 |
GO:0045137 | development of primary sexual characteristics | 22/885 | 223/18670 | 0.0010 | 0.0086 | 22 |
GO:0010463 | mesenchymal cell proliferation | 8/885 | 44/18670 | 0.0010 | 0.0086 | 8 |
GO:0042987 | amyloid precursor protein catabolic process | 8/885 | 44/18670 | 0.0010 | 0.0086 | 8 |
GO:1901028 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 8/885 | 44/18670 | 0.0010 | 0.0086 | 8 |
GO:0090316 | positive regulation of intracellular protein transport | 17/885 | 153/18670 | 0.0010 | 0.0086 | 17 |
GO:0048678 | response to axon injury | 11/885 | 77/18670 | 0.0010 | 0.0088 | 11 |
GO:0051937 | catecholamine transport | 11/885 | 77/18670 | 0.0010 | 0.0088 | 11 |
GO:0051048 | negative regulation of secretion | 23/885 | 238/18670 | 0.0010 | 0.0088 | 23 |
GO:0032602 | chemokine production | 12/885 | 89/18670 | 0.0010 | 0.0088 | 12 |
GO:0002443 | leukocyte mediated immunity | 62/885 | 874/18670 | 0.0010 | 0.0089 | 62 |
GO:0030218 | erythrocyte differentiation | 14/885 | 114/18670 | 0.0010 | 0.0089 | 14 |
GO:0009123 | nucleoside monophosphate metabolic process | 32/885 | 375/18670 | 0.0010 | 0.0089 | 32 |
GO:0046888 | negative regulation of hormone secretion | 10/885 | 66/18670 | 0.0010 | 0.0092 | 10 |
GO:1905710 | positive regulation of membrane permeability | 10/885 | 66/18670 | 0.0010 | 0.0092 | 10 |
GO:0017156 | calcium ion regulated exocytosis | 17/885 | 154/18670 | 0.0010 | 0.0092 | 17 |
GO:0036230 | granulocyte activation | 40/885 | 504/18670 | 0.0010 | 0.0092 | 40 |
GO:0051402 | neuron apoptotic process | 23/885 | 239/18670 | 0.0010 | 0.0092 | 23 |
GO:0043523 | regulation of neuron apoptotic process | 21/885 | 210/18670 | 0.0010 | 0.0092 | 21 |
GO:0010522 | regulation of calcium ion transport into cytosol | 13/885 | 102/18670 | 0.0011 | 0.0093 | 13 |
GO:0001763 | morphogenesis of a branching structure | 20/885 | 196/18670 | 0.0011 | 0.0093 | 20 |
GO:0002685 | regulation of leukocyte migration | 20/885 | 196/18670 | 0.0011 | 0.0093 | 20 |
GO:0050808 | synapse organization | 34/885 | 408/18670 | 0.0011 | 0.0093 | 34 |
GO:0001738 | morphogenesis of a polarized epithelium | 16/885 | 141/18670 | 0.0011 | 0.0094 | 16 |
GO:0008286 | insulin receptor signaling pathway | 16/885 | 141/18670 | 0.0011 | 0.0094 | 16 |
GO:0010948 | negative regulation of cell cycle process | 31/885 | 361/18670 | 0.0011 | 0.0094 | 31 |
GO:0032496 | response to lipopolysaccharide | 29/885 | 330/18670 | 0.0011 | 0.0094 | 29 |
GO:0033143 | regulation of intracellular steroid hormone receptor signaling pathway | 11/885 | 78/18670 | 0.0011 | 0.0095 | 11 |
GO:0002687 | positive regulation of leukocyte migration | 15/885 | 128/18670 | 0.0011 | 0.0095 | 15 |
GO:0032606 | type I interferon production | 15/885 | 128/18670 | 0.0011 | 0.0095 | 15 |
GO:0006813 | potassium ion transport | 23/885 | 240/18670 | 0.0011 | 0.0095 | 23 |
GO:0032735 | positive regulation of interleukin-12 production | 7/885 | 35/18670 | 0.0011 | 0.0095 | 7 |
GO:0110111 | negative regulation of animal organ morphogenesis | 7/885 | 35/18670 | 0.0011 | 0.0095 | 7 |
GO:1902991 | regulation of amyloid precursor protein catabolic process | 7/885 | 35/18670 | 0.0011 | 0.0095 | 7 |
GO:0070372 | regulation of ERK1 and ERK2 cascade | 27/885 | 300/18670 | 0.0011 | 0.0096 | 27 |
GO:0001974 | blood vessel remodeling | 8/885 | 45/18670 | 0.0011 | 0.0096 | 8 |
GO:0009141 | nucleoside triphosphate metabolic process | 31/885 | 362/18670 | 0.0011 | 0.0097 | 31 |
GO:0034114 | regulation of heterotypic cell-cell adhesion | 6/885 | 26/18670 | 0.0011 | 0.0098 | 6 |
GO:0060037 | pharyngeal system development | 6/885 | 26/18670 | 0.0011 | 0.0098 | 6 |
GO:0032091 | negative regulation of protein binding | 13/885 | 103/18670 | 0.0012 | 0.0099 | 13 |
GO:0048259 | regulation of receptor-mediated endocytosis | 13/885 | 103/18670 | 0.0012 | 0.0099 | 13 |
GO:0010769 | regulation of cell morphogenesis involved in differentiation | 27/885 | 301/18670 | 0.0012 | 0.0099 | 27 |
ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
---|---|---|---|---|---|---|
GO:1903047 | mitotic cell cycle process | 83/594 | 873/18670 | 0.0000 | 0.0000 | 83 |
GO:0010948 | negative regulation of cell cycle process | 51/594 | 361/18670 | 0.0000 | 0.0000 | 51 |
GO:0002366 | leukocyte activation involved in immune response | 73/594 | 707/18670 | 0.0000 | 0.0000 | 73 |
GO:0002263 | cell activation involved in immune response | 73/594 | 711/18670 | 0.0000 | 0.0000 | 73 |
GO:0002274 | myeloid leukocyte activation | 67/594 | 651/18670 | 0.0000 | 0.0000 | 67 |
GO:0016032 | viral process | 77/594 | 833/18670 | 0.0000 | 0.0000 | 77 |
GO:0002443 | leukocyte mediated immunity | 79/594 | 874/18670 | 0.0000 | 0.0000 | 79 |
GO:0044419 | interspecies interaction between organisms | 82/594 | 932/18670 | 0.0000 | 0.0000 | 82 |
GO:0044403 | symbiont process | 79/594 | 884/18670 | 0.0000 | 0.0000 | 79 |
GO:0036230 | granulocyte activation | 57/594 | 504/18670 | 0.0000 | 0.0000 | 57 |
GO:0044772 | mitotic cell cycle phase transition | 62/594 | 588/18670 | 0.0000 | 0.0000 | 62 |
GO:0002275 | myeloid cell activation involved in immune response | 59/594 | 544/18670 | 0.0000 | 0.0000 | 59 |
GO:0042119 | neutrophil activation | 56/594 | 498/18670 | 0.0000 | 0.0000 | 56 |
GO:0044770 | cell cycle phase transition | 64/594 | 631/18670 | 0.0000 | 0.0000 | 64 |
GO:0043299 | leukocyte degranulation | 58/594 | 534/18670 | 0.0000 | 0.0000 | 58 |
GO:0002444 | myeloid leukocyte mediated immunity | 59/594 | 551/18670 | 0.0000 | 0.0000 | 59 |
GO:0045055 | regulated exocytosis | 72/594 | 794/18670 | 0.0000 | 0.0000 | 72 |
GO:0007346 | regulation of mitotic cell cycle | 64/594 | 656/18670 | 0.0000 | 0.0000 | 64 |
GO:0002283 | neutrophil activation involved in immune response | 54/594 | 488/18670 | 0.0000 | 0.0000 | 54 |
GO:0010564 | regulation of cell cycle process | 71/594 | 789/18670 | 0.0000 | 0.0000 | 71 |
GO:0043312 | neutrophil degranulation | 53/594 | 485/18670 | 0.0000 | 0.0000 | 53 |
GO:0045786 | negative regulation of cell cycle | 62/594 | 641/18670 | 0.0000 | 0.0000 | 62 |
GO:0006887 | exocytosis | 76/594 | 903/18670 | 0.0000 | 0.0000 | 76 |
GO:0002446 | neutrophil mediated immunity | 53/594 | 499/18670 | 0.0000 | 0.0000 | 53 |
GO:1901990 | regulation of mitotic cell cycle phase transition | 48/594 | 444/18670 | 0.0000 | 0.0000 | 48 |
GO:1901991 | negative regulation of mitotic cell cycle phase transition | 35/594 | 248/18670 | 0.0000 | 0.0000 | 35 |
GO:1903311 | regulation of mRNA metabolic process | 40/594 | 324/18670 | 0.0000 | 0.0000 | 40 |
GO:0006974 | cellular response to DNA damage stimulus | 70/594 | 854/18670 | 0.0000 | 0.0000 | 70 |
GO:0006260 | DNA replication | 36/594 | 274/18670 | 0.0000 | 0.0000 | 36 |
GO:1901987 | regulation of cell cycle phase transition | 49/594 | 480/18670 | 0.0000 | 0.0000 | 49 |
GO:0045930 | negative regulation of mitotic cell cycle | 40/594 | 338/18670 | 0.0000 | 0.0000 | 40 |
GO:1901988 | negative regulation of cell cycle phase transition | 35/594 | 267/18670 | 0.0000 | 0.0000 | 35 |
GO:0002520 | immune system development | 75/594 | 985/18670 | 0.0000 | 0.0000 | 75 |
GO:0030097 | hemopoiesis | 70/594 | 887/18670 | 0.0000 | 0.0000 | 70 |
GO:0002244 | hematopoietic progenitor cell differentiation | 27/594 | 166/18670 | 0.0000 | 0.0000 | 27 |
GO:0000122 | negative regulation of transcription by RNA polymerase II | 67/594 | 839/18670 | 0.0000 | 0.0000 | 67 |
GO:0048534 | hematopoietic or lymphoid organ development | 71/594 | 929/18670 | 0.0000 | 0.0000 | 71 |
GO:1902749 | regulation of cell cycle G2/M phase transition | 30/594 | 213/18670 | 0.0000 | 0.0000 | 30 |
GO:0006281 | DNA repair | 51/594 | 552/18670 | 0.0000 | 0.0000 | 51 |
GO:0060218 | hematopoietic stem cell differentiation | 19/594 | 83/18670 | 0.0000 | 0.0000 | 19 |
GO:0033993 | response to lipid | 70/594 | 923/18670 | 0.0000 | 0.0000 | 70 |
GO:0016071 | mRNA metabolic process | 67/594 | 877/18670 | 0.0000 | 0.0000 | 67 |
GO:0019221 | cytokine-mediated signaling pathway | 63/594 | 798/18670 | 0.0000 | 0.0000 | 63 |
GO:0010389 | regulation of G2/M transition of mitotic cell cycle | 28/594 | 196/18670 | 0.0000 | 0.0000 | 28 |
GO:1902036 | regulation of hematopoietic stem cell differentiation | 17/594 | 72/18670 | 0.0000 | 0.0000 | 17 |
GO:0033044 | regulation of chromosome organization | 37/594 | 342/18670 | 0.0000 | 0.0000 | 37 |
GO:0000082 | G1/S transition of mitotic cell cycle | 33/594 | 279/18670 | 0.0000 | 0.0000 | 33 |
GO:0070482 | response to oxygen levels | 40/594 | 394/18670 | 0.0000 | 0.0000 | 40 |
GO:0006403 | RNA localization | 29/594 | 230/18670 | 0.0000 | 0.0000 | 29 |
GO:2001252 | positive regulation of chromosome organization | 25/594 | 174/18670 | 0.0000 | 0.0000 | 25 |
GO:0002521 | leukocyte differentiation | 46/594 | 515/18670 | 0.0000 | 0.0000 | 46 |
GO:0001666 | response to hypoxia | 37/594 | 359/18670 | 0.0000 | 0.0000 | 37 |
GO:0070198 | protein localization to chromosome, telomeric region | 11/594 | 28/18670 | 0.0000 | 0.0000 | 11 |
GO:0019439 | aromatic compound catabolic process | 56/594 | 712/18670 | 0.0000 | 0.0000 | 56 |
GO:0044839 | cell cycle G2/M phase transition | 31/594 | 266/18670 | 0.0000 | 0.0000 | 31 |
GO:0044843 | cell cycle G1/S phase transition | 33/594 | 298/18670 | 0.0000 | 0.0000 | 33 |
GO:2000736 | regulation of stem cell differentiation | 20/594 | 116/18670 | 0.0000 | 0.0000 | 20 |
GO:0036293 | response to decreased oxygen levels | 37/594 | 370/18670 | 0.0000 | 0.0000 | 37 |
GO:0000165 | MAPK cascade | 67/594 | 958/18670 | 0.0000 | 0.0000 | 67 |
GO:1901532 | regulation of hematopoietic progenitor cell differentiation | 17/594 | 85/18670 | 0.0000 | 0.0000 | 17 |
GO:0046700 | heterocycle catabolic process | 54/594 | 695/18670 | 0.0000 | 0.0000 | 54 |
GO:0044270 | cellular nitrogen compound catabolic process | 54/594 | 696/18670 | 0.0000 | 0.0000 | 54 |
GO:0000086 | G2/M transition of mitotic cell cycle | 29/594 | 247/18670 | 0.0000 | 0.0000 | 29 |
GO:0023014 | signal transduction by protein phosphorylation | 67/594 | 969/18670 | 0.0000 | 0.0000 | 67 |
GO:1901361 | organic cyclic compound catabolic process | 56/594 | 745/18670 | 0.0000 | 0.0000 | 56 |
GO:0031329 | regulation of cellular catabolic process | 62/594 | 871/18670 | 0.0000 | 0.0000 | 62 |
GO:0034655 | nucleobase-containing compound catabolic process | 51/594 | 648/18670 | 0.0000 | 0.0000 | 51 |
GO:1903405 | protein localization to nuclear body | 7/594 | 10/18670 | 0.0000 | 0.0000 | 7 |
GO:1904851 | positive regulation of establishment of protein localization to telomere | 7/594 | 10/18670 | 0.0000 | 0.0000 | 7 |
GO:1904867 | protein localization to Cajal body | 7/594 | 10/18670 | 0.0000 | 0.0000 | 7 |
GO:0042110 | T cell activation | 41/594 | 464/18670 | 0.0000 | 0.0000 | 41 |
GO:0051052 | regulation of DNA metabolic process | 39/594 | 429/18670 | 0.0000 | 0.0000 | 39 |
GO:0043487 | regulation of RNA stability | 24/594 | 183/18670 | 0.0000 | 0.0000 | 24 |
GO:0033238 | regulation of cellular amine metabolic process | 16/594 | 81/18670 | 0.0000 | 0.0000 | 16 |
GO:0044106 | cellular amine metabolic process | 20/594 | 129/18670 | 0.0000 | 0.0000 | 20 |
GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle | 17/594 | 93/18670 | 0.0000 | 0.0000 | 17 |
GO:0044786 | cell cycle DNA replication | 15/594 | 71/18670 | 0.0000 | 0.0000 | 15 |
GO:0034502 | protein localization to chromosome | 16/594 | 82/18670 | 0.0000 | 0.0000 | 16 |
GO:0070201 | regulation of establishment of protein localization | 55/594 | 746/18670 | 0.0000 | 0.0000 | 55 |
GO:0030162 | regulation of proteolysis | 59/594 | 831/18670 | 0.0000 | 0.0000 | 59 |
GO:0032392 | DNA geometric change | 19/594 | 119/18670 | 0.0000 | 0.0000 | 19 |
GO:0046649 | lymphocyte activation | 54/594 | 733/18670 | 0.0000 | 0.0000 | 54 |
GO:0070203 | regulation of establishment of protein localization to telomere | 7/594 | 11/18670 | 0.0000 | 0.0000 | 7 |
GO:0000723 | telomere maintenance | 22/594 | 162/18670 | 0.0000 | 0.0000 | 22 |
GO:0043488 | regulation of mRNA stability | 23/594 | 177/18670 | 0.0000 | 0.0000 | 23 |
GO:0070555 | response to interleukin-1 | 25/594 | 207/18670 | 0.0000 | 0.0000 | 25 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 15/594 | 75/18670 | 0.0000 | 0.0000 | 15 |
GO:0071824 | protein-DNA complex subunit organization | 30/594 | 288/18670 | 0.0000 | 0.0000 | 30 |
GO:0009308 | amine metabolic process | 20/594 | 138/18670 | 0.0000 | 0.0000 | 20 |
GO:0010638 | positive regulation of organelle organization | 48/594 | 623/18670 | 0.0000 | 0.0000 | 48 |
GO:0019882 | antigen processing and presentation | 26/594 | 226/18670 | 0.0000 | 0.0000 | 26 |
GO:0017144 | drug metabolic process | 59/594 | 851/18670 | 0.0000 | 0.0000 | 59 |
GO:0071897 | DNA biosynthetic process | 24/594 | 196/18670 | 0.0000 | 0.0000 | 24 |
GO:0002237 | response to molecule of bacterial origin | 33/594 | 343/18670 | 0.0000 | 0.0000 | 33 |
GO:0006261 | DNA-dependent DNA replication | 21/594 | 153/18670 | 0.0000 | 0.0000 | 21 |
GO:0045088 | regulation of innate immune response | 39/594 | 452/18670 | 0.0000 | 0.0000 | 39 |
GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 35/594 | 379/18670 | 0.0000 | 0.0000 | 35 |
GO:0000398 | mRNA splicing, via spliceosome | 35/594 | 379/18670 | 0.0000 | 0.0000 | 35 |
GO:0071103 | DNA conformation change | 32/594 | 327/18670 | 0.0000 | 0.0000 | 32 |
GO:2000573 | positive regulation of DNA biosynthetic process | 14/594 | 67/18670 | 0.0000 | 0.0000 | 14 |
GO:0033365 | protein localization to organelle | 62/594 | 922/18670 | 0.0000 | 0.0000 | 62 |
GO:0070202 | regulation of establishment of protein localization to chromosome | 7/594 | 12/18670 | 0.0000 | 0.0000 | 7 |
GO:1904816 | positive regulation of protein localization to chromosome, telomeric region | 7/594 | 12/18670 | 0.0000 | 0.0000 | 7 |
GO:1990173 | protein localization to nucleoplasm | 7/594 | 12/18670 | 0.0000 | 0.0000 | 7 |
GO:0000375 | RNA splicing, via transesterification reactions | 35/594 | 382/18670 | 0.0000 | 0.0000 | 35 |
GO:0060249 | anatomical structure homeostasis | 38/594 | 437/18670 | 0.0000 | 0.0000 | 38 |
GO:0061013 | regulation of mRNA catabolic process | 24/594 | 199/18670 | 0.0000 | 0.0000 | 24 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 15/594 | 79/18670 | 0.0000 | 0.0000 | 15 |
GO:0065004 | protein-DNA complex assembly | 27/594 | 248/18670 | 0.0000 | 0.0000 | 27 |
GO:0006352 | DNA-templated transcription, initiation | 27/594 | 249/18670 | 0.0000 | 0.0000 | 27 |
GO:0031145 | anaphase-promoting complex-dependent catabolic process | 15/594 | 81/18670 | 0.0000 | 0.0000 | 15 |
GO:0032204 | regulation of telomere maintenance | 15/594 | 81/18670 | 0.0000 | 0.0000 | 15 |
GO:1902750 | negative regulation of cell cycle G2/M phase transition | 17/594 | 105/18670 | 0.0000 | 0.0000 | 17 |
GO:0006397 | mRNA processing | 43/594 | 541/18670 | 0.0000 | 0.0000 | 43 |
GO:0014070 | response to organic cyclic compound | 61/594 | 915/18670 | 0.0000 | 0.0000 | 61 |
GO:0033260 | nuclear DNA replication | 13/594 | 60/18670 | 0.0000 | 0.0000 | 13 |
GO:0032200 | telomere organization | 22/594 | 175/18670 | 0.0000 | 0.0000 | 22 |
GO:0009314 | response to radiation | 38/594 | 448/18670 | 0.0000 | 0.0000 | 38 |
GO:2000278 | regulation of DNA biosynthetic process | 17/594 | 108/18670 | 0.0000 | 0.0000 | 17 |
GO:0030155 | regulation of cell adhesion | 50/594 | 691/18670 | 0.0000 | 0.0000 | 50 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 16/594 | 96/18670 | 0.0000 | 0.0000 | 16 |
GO:0071396 | cellular response to lipid | 46/594 | 610/18670 | 0.0000 | 0.0000 | 46 |
GO:0006521 | regulation of cellular amino acid metabolic process | 13/594 | 62/18670 | 0.0000 | 0.0000 | 13 |
GO:1904356 | regulation of telomere maintenance via telomere lengthening | 13/594 | 62/18670 | 0.0000 | 0.0000 | 13 |
GO:0071347 | cellular response to interleukin-1 | 22/594 | 179/18670 | 0.0000 | 0.0000 | 22 |
GO:0010243 | response to organonitrogen compound | 64/594 | 998/18670 | 0.0000 | 0.0000 | 64 |
GO:0050684 | regulation of mRNA processing | 19/594 | 137/18670 | 0.0000 | 0.0000 | 19 |
GO:0051169 | nuclear transport | 32/594 | 346/18670 | 0.0000 | 0.0000 | 32 |
GO:0051054 | positive regulation of DNA metabolic process | 25/594 | 228/18670 | 0.0000 | 0.0000 | 25 |
GO:0009894 | regulation of catabolic process | 63/594 | 979/18670 | 0.0000 | 0.0000 | 63 |
GO:1904814 | regulation of protein localization to chromosome, telomeric region | 7/594 | 14/18670 | 0.0000 | 0.0000 | 7 |
GO:0010035 | response to inorganic substance | 43/594 | 562/18670 | 0.0000 | 0.0000 | 43 |
GO:0050778 | positive regulation of immune response | 59/594 | 902/18670 | 0.0000 | 0.0000 | 59 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 14/594 | 77/18670 | 0.0000 | 0.0000 | 14 |
GO:0008380 | RNA splicing | 38/594 | 469/18670 | 0.0000 | 0.0000 | 38 |
GO:0007568 | aging | 30/594 | 321/18670 | 0.0000 | 0.0000 | 30 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 22/594 | 188/18670 | 0.0000 | 0.0000 | 22 |
GO:0002220 | innate immune response activating cell surface receptor signaling pathway | 17/594 | 116/18670 | 0.0000 | 0.0000 | 17 |
GO:1904358 | positive regulation of telomere maintenance via telomere lengthening | 10/594 | 37/18670 | 0.0000 | 0.0000 | 10 |
GO:0006325 | chromatin organization | 54/594 | 800/18670 | 0.0000 | 0.0000 | 54 |
GO:0052547 | regulation of peptidase activity | 37/594 | 452/18670 | 0.0000 | 0.0000 | 37 |
GO:1904874 | positive regulation of telomerase RNA localization to Cajal body | 7/594 | 15/18670 | 0.0000 | 0.0000 | 7 |
GO:0006913 | nucleocytoplasmic transport | 31/594 | 343/18670 | 0.0000 | 0.0000 | 31 |
GO:1903706 | regulation of hemopoiesis | 38/594 | 475/18670 | 0.0000 | 0.0000 | 38 |
GO:0048863 | stem cell differentiation | 26/594 | 257/18670 | 0.0000 | 0.0000 | 26 |
GO:0006310 | DNA recombination | 28/594 | 292/18670 | 0.0000 | 0.0000 | 28 |
GO:0062012 | regulation of small molecule metabolic process | 37/594 | 459/18670 | 0.0000 | 0.0000 | 37 |
GO:0050821 | protein stabilization | 21/594 | 178/18670 | 0.0000 | 0.0000 | 21 |
GO:0032496 | response to lipopolysaccharide | 30/594 | 330/18670 | 0.0000 | 0.0000 | 30 |
GO:0010833 | telomere maintenance via telomere lengthening | 14/594 | 82/18670 | 0.0000 | 0.0000 | 14 |
GO:0070200 | establishment of protein localization to telomere | 7/594 | 16/18670 | 0.0000 | 0.0000 | 7 |
GO:0043069 | negative regulation of programmed cell death | 59/594 | 932/18670 | 0.0000 | 0.0000 | 59 |
GO:0002218 | activation of innate immune response | 29/594 | 319/18670 | 0.0000 | 0.0000 | 29 |
GO:0031647 | regulation of protein stability | 27/594 | 284/18670 | 0.0000 | 0.0000 | 27 |
GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle | 17/594 | 125/18670 | 0.0000 | 0.0000 | 17 |
GO:0032206 | positive regulation of telomere maintenance | 11/594 | 51/18670 | 0.0000 | 0.0000 | 11 |
GO:0071453 | cellular response to oxygen levels | 24/594 | 234/18670 | 0.0000 | 0.0000 | 24 |
GO:0009725 | response to hormone | 61/594 | 987/18670 | 0.0000 | 0.0000 | 61 |
GO:0006401 | RNA catabolic process | 33/594 | 397/18670 | 0.0000 | 0.0000 | 33 |
GO:0002223 | stimulatory C-type lectin receptor signaling pathway | 16/594 | 113/18670 | 0.0000 | 0.0000 | 16 |
GO:0070498 | interleukin-1-mediated signaling pathway | 15/594 | 100/18670 | 0.0000 | 0.0000 | 15 |
GO:0045089 | positive regulation of innate immune response | 32/594 | 381/18670 | 0.0000 | 0.0000 | 32 |
GO:0002576 | platelet degranulation | 17/594 | 128/18670 | 0.0000 | 0.0000 | 17 |
GO:1904872 | regulation of telomerase RNA localization to Cajal body | 7/594 | 18/18670 | 0.0000 | 0.0000 | 7 |
GO:0071456 | cellular response to hypoxia | 22/594 | 207/18670 | 0.0000 | 0.0000 | 22 |
GO:0002478 | antigen processing and presentation of exogenous peptide antigen | 20/594 | 175/18670 | 0.0000 | 0.0000 | 20 |
GO:0032212 | positive regulation of telomere maintenance via telomerase | 9/594 | 34/18670 | 0.0000 | 0.0000 | 9 |
GO:0071478 | cellular response to radiation | 21/594 | 191/18670 | 0.0000 | 0.0000 | 21 |
GO:1901699 | cellular response to nitrogen compound | 45/594 | 648/18670 | 0.0000 | 0.0000 | 45 |
GO:0032210 | regulation of telomere maintenance via telomerase | 11/594 | 54/18670 | 0.0000 | 0.0000 | 11 |
GO:0006278 | RNA-dependent DNA biosynthetic process | 13/594 | 77/18670 | 0.0000 | 0.0000 | 13 |
GO:1902807 | negative regulation of cell cycle G1/S phase transition | 17/594 | 131/18670 | 0.0000 | 0.0000 | 17 |
GO:0071214 | cellular response to abiotic stimulus | 29/594 | 331/18670 | 0.0000 | 0.0000 | 29 |
GO:0104004 | cellular response to environmental stimulus | 29/594 | 331/18670 | 0.0000 | 0.0000 | 29 |
GO:0070897 | transcription preinitiation complex assembly | 10/594 | 44/18670 | 0.0000 | 0.0000 | 10 |
GO:0051050 | positive regulation of transport | 60/594 | 982/18670 | 0.0000 | 0.0000 | 60 |
GO:0002764 | immune response-regulating signaling pathway | 46/594 | 675/18670 | 0.0000 | 0.0000 | 46 |
GO:0090670 | RNA localization to Cajal body | 7/594 | 19/18670 | 0.0000 | 0.0000 | 7 |
GO:0090671 | telomerase RNA localization to Cajal body | 7/594 | 19/18670 | 0.0000 | 0.0000 | 7 |
GO:0090672 | telomerase RNA localization | 7/594 | 19/18670 | 0.0000 | 0.0000 | 7 |
GO:0090685 | RNA localization to nucleus | 7/594 | 19/18670 | 0.0000 | 0.0000 | 7 |
GO:0090407 | organophosphate biosynthetic process | 47/594 | 699/18670 | 0.0000 | 0.0000 | 47 |
GO:0009611 | response to wounding | 46/594 | 678/18670 | 0.0000 | 0.0000 | 46 |
GO:0045597 | positive regulation of cell differentiation | 60/594 | 991/18670 | 0.0000 | 0.0000 | 60 |
GO:0002253 | activation of immune response | 48/594 | 724/18670 | 0.0000 | 0.0000 | 48 |
GO:0080135 | regulation of cellular response to stress | 49/594 | 746/18670 | 0.0000 | 0.0000 | 49 |
GO:0035567 | non-canonical Wnt signaling pathway | 18/594 | 150/18670 | 0.0000 | 0.0000 | 18 |
GO:0042180 | cellular ketone metabolic process | 24/594 | 248/18670 | 0.0000 | 0.0000 | 24 |
GO:0051338 | regulation of transferase activity | 59/594 | 972/18670 | 0.0000 | 0.0000 | 59 |
GO:0051301 | cell division | 42/594 | 598/18670 | 0.0000 | 0.0000 | 42 |
GO:0019884 | antigen processing and presentation of exogenous antigen | 20/594 | 182/18670 | 0.0000 | 0.0000 | 20 |
GO:0051345 | positive regulation of hydrolase activity | 50/594 | 771/18670 | 0.0000 | 0.0000 | 50 |
GO:0008284 | positive regulation of cell proliferation | 58/594 | 951/18670 | 0.0000 | 0.0000 | 58 |
GO:0060341 | regulation of cellular localization | 56/594 | 906/18670 | 0.0000 | 0.0000 | 56 |
GO:0060071 | Wnt signaling pathway, planar cell polarity pathway | 15/594 | 108/18670 | 0.0000 | 0.0000 | 15 |
GO:0036294 | cellular response to decreased oxygen levels | 22/594 | 217/18670 | 0.0000 | 0.0000 | 22 |
GO:2000045 | regulation of G1/S transition of mitotic cell cycle | 20/594 | 184/18670 | 0.0000 | 0.0000 | 20 |
GO:0007004 | telomere maintenance via telomerase | 12/594 | 70/18670 | 0.0000 | 0.0001 | 12 |
GO:0001736 | establishment of planar polarity | 16/594 | 124/18670 | 0.0000 | 0.0001 | 16 |
GO:0007164 | establishment of tissue polarity | 16/594 | 124/18670 | 0.0000 | 0.0001 | 16 |
GO:0032508 | DNA duplex unwinding | 15/594 | 110/18670 | 0.0000 | 0.0001 | 15 |
GO:0090175 | regulation of establishment of planar polarity | 15/594 | 110/18670 | 0.0000 | 0.0001 | 15 |
GO:0045936 | negative regulation of phosphate metabolic process | 41/594 | 586/18670 | 0.0000 | 0.0001 | 41 |
GO:0042063 | gliogenesis | 26/594 | 290/18670 | 0.0000 | 0.0001 | 26 |
GO:0010563 | negative regulation of phosphorus metabolic process | 41/594 | 587/18670 | 0.0000 | 0.0001 | 41 |
GO:0009636 | response to toxic substance | 38/594 | 525/18670 | 0.0000 | 0.0001 | 38 |
GO:0002573 | myeloid leukocyte differentiation | 21/594 | 204/18670 | 0.0000 | 0.0001 | 21 |
GO:0006091 | generation of precursor metabolites and energy | 38/594 | 526/18670 | 0.0000 | 0.0001 | 38 |
GO:0052548 | regulation of endopeptidase activity | 33/594 | 425/18670 | 0.0000 | 0.0001 | 33 |
GO:0009165 | nucleotide biosynthetic process | 31/594 | 386/18670 | 0.0000 | 0.0001 | 31 |
GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 37/594 | 506/18670 | 0.0000 | 0.0001 | 37 |
GO:0048002 | antigen processing and presentation of peptide antigen | 20/594 | 189/18670 | 0.0000 | 0.0001 | 20 |
GO:0030217 | T cell differentiation | 23/594 | 240/18670 | 0.0000 | 0.0001 | 23 |
GO:0009617 | response to bacterium | 46/594 | 699/18670 | 0.0000 | 0.0001 | 46 |
GO:0043620 | regulation of DNA-templated transcription in response to stress | 16/594 | 127/18670 | 0.0000 | 0.0001 | 16 |
GO:1901293 | nucleoside phosphate biosynthetic process | 31/594 | 390/18670 | 0.0000 | 0.0001 | 31 |
GO:0043408 | regulation of MAPK cascade | 49/594 | 768/18670 | 0.0000 | 0.0001 | 49 |
GO:0050792 | regulation of viral process | 21/594 | 208/18670 | 0.0000 | 0.0001 | 21 |
GO:0030098 | lymphocyte differentiation | 29/594 | 353/18670 | 0.0000 | 0.0001 | 29 |
GO:0002758 | innate immune response-activating signal transduction | 26/594 | 298/18670 | 0.0000 | 0.0001 | 26 |
GO:0006457 | protein folding | 22/594 | 227/18670 | 0.0000 | 0.0001 | 22 |
GO:0043066 | negative regulation of apoptotic process | 55/594 | 911/18670 | 0.0000 | 0.0001 | 55 |
GO:0009117 | nucleotide metabolic process | 46/594 | 709/18670 | 0.0000 | 0.0001 | 46 |
GO:0006353 | DNA-templated transcription, termination | 12/594 | 75/18670 | 0.0000 | 0.0001 | 12 |
GO:1904951 | positive regulation of establishment of protein localization | 34/594 | 456/18670 | 0.0000 | 0.0001 | 34 |
GO:0055086 | nucleobase-containing small molecule metabolic process | 50/594 | 801/18670 | 0.0000 | 0.0001 | 50 |
GO:0010212 | response to ionizing radiation | 17/594 | 147/18670 | 0.0000 | 0.0001 | 17 |
GO:0034599 | cellular response to oxidative stress | 26/594 | 302/18670 | 0.0000 | 0.0001 | 26 |
GO:0051236 | establishment of RNA localization | 20/594 | 196/18670 | 0.0000 | 0.0001 | 20 |
GO:0031349 | positive regulation of defense response | 37/594 | 521/18670 | 0.0000 | 0.0001 | 37 |
GO:0006753 | nucleoside phosphate metabolic process | 46/594 | 716/18670 | 0.0000 | 0.0001 | 46 |
GO:0044283 | small molecule biosynthetic process | 50/594 | 807/18670 | 0.0000 | 0.0001 | 50 |
GO:1903827 | regulation of cellular protein localization | 37/594 | 524/18670 | 0.0000 | 0.0001 | 37 |
GO:0045862 | positive regulation of proteolysis | 29/594 | 363/18670 | 0.0000 | 0.0001 | 29 |
GO:0022407 | regulation of cell-cell adhesion | 31/594 | 403/18670 | 0.0000 | 0.0001 | 31 |
GO:0019725 | cellular homeostasis | 57/594 | 970/18670 | 0.0000 | 0.0001 | 57 |
GO:0031347 | regulation of defense response | 54/594 | 901/18670 | 0.0000 | 0.0001 | 54 |
GO:0043484 | regulation of RNA splicing | 16/594 | 135/18670 | 0.0000 | 0.0001 | 16 |
GO:0038061 | NIK/NF-kappaB signaling | 19/594 | 183/18670 | 0.0000 | 0.0001 | 19 |
GO:0016999 | antibiotic metabolic process | 17/594 | 151/18670 | 0.0000 | 0.0001 | 17 |
GO:0043900 | regulation of multi-organism process | 31/594 | 405/18670 | 0.0000 | 0.0001 | 31 |
GO:2000027 | regulation of animal organ morphogenesis | 23/594 | 253/18670 | 0.0000 | 0.0001 | 23 |
GO:0006520 | cellular amino acid metabolic process | 29/594 | 366/18670 | 0.0000 | 0.0001 | 29 |
GO:0043618 | regulation of transcription from RNA polymerase II promoter in response to stress | 15/594 | 121/18670 | 0.0000 | 0.0002 | 15 |
GO:0071216 | cellular response to biotic stimulus | 22/594 | 236/18670 | 0.0000 | 0.0002 | 22 |
GO:0034614 | cellular response to reactive oxygen species | 18/594 | 168/18670 | 0.0000 | 0.0002 | 18 |
GO:0044087 | regulation of cellular component biogenesis | 56/594 | 954/18670 | 0.0000 | 0.0002 | 56 |
GO:1902806 | regulation of cell cycle G1/S phase transition | 20/594 | 202/18670 | 0.0000 | 0.0002 | 20 |
GO:0010720 | positive regulation of cell development | 38/594 | 553/18670 | 0.0000 | 0.0002 | 38 |
GO:0035690 | cellular response to drug | 29/594 | 369/18670 | 0.0000 | 0.0002 | 29 |
GO:0002757 | immune response-activating signal transduction | 42/594 | 641/18670 | 0.0000 | 0.0002 | 42 |
GO:0006275 | regulation of DNA replication | 14/594 | 108/18670 | 0.0000 | 0.0002 | 14 |
GO:0010942 | positive regulation of cell death | 46/594 | 730/18670 | 0.0000 | 0.0002 | 46 |
GO:0043903 | regulation of symbiosis, encompassing mutualism through parasitism | 21/594 | 222/18670 | 0.0000 | 0.0002 | 21 |
GO:0002429 | immune response-activating cell surface receptor signaling pathway | 34/594 | 473/18670 | 0.0000 | 0.0002 | 34 |
GO:0006289 | nucleotide-excision repair | 14/594 | 109/18670 | 0.0000 | 0.0002 | 14 |
GO:0008334 | histone mRNA metabolic process | 7/594 | 25/18670 | 0.0000 | 0.0002 | 7 |
GO:0070199 | establishment of protein localization to chromosome | 7/594 | 25/18670 | 0.0000 | 0.0002 | 7 |
GO:0010332 | response to gamma radiation | 10/594 | 56/18670 | 0.0000 | 0.0002 | 10 |
GO:0050769 | positive regulation of neurogenesis | 34/594 | 474/18670 | 0.0000 | 0.0002 | 34 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 13/594 | 95/18670 | 0.0000 | 0.0002 | 13 |
GO:0038093 | Fc receptor signaling pathway | 22/594 | 241/18670 | 0.0000 | 0.0002 | 22 |
GO:0006518 | peptide metabolic process | 53/594 | 894/18670 | 0.0000 | 0.0002 | 53 |
GO:0006418 | tRNA aminoacylation for protein translation | 9/594 | 45/18670 | 0.0000 | 0.0002 | 9 |
GO:0009123 | nucleoside monophosphate metabolic process | 29/594 | 375/18670 | 0.0000 | 0.0002 | 29 |
GO:0070661 | leukocyte proliferation | 25/594 | 298/18670 | 0.0000 | 0.0002 | 25 |
GO:0001738 | morphogenesis of a polarized epithelium | 16/594 | 141/18670 | 0.0000 | 0.0002 | 16 |
GO:0009411 | response to UV | 16/594 | 141/18670 | 0.0000 | 0.0002 | 16 |
GO:0009124 | nucleoside monophosphate biosynthetic process | 20/594 | 208/18670 | 0.0000 | 0.0002 | 20 |
GO:0043065 | positive regulation of apoptotic process | 43/594 | 672/18670 | 0.0000 | 0.0002 | 43 |
GO:0034504 | protein localization to nucleus | 23/594 | 262/18670 | 0.0000 | 0.0002 | 23 |
GO:0071417 | cellular response to organonitrogen compound | 39/594 | 585/18670 | 0.0000 | 0.0002 | 39 |
GO:0050766 | positive regulation of phagocytosis | 11/594 | 70/18670 | 0.0000 | 0.0002 | 11 |
GO:0001817 | regulation of cytokine production | 45/594 | 719/18670 | 0.0000 | 0.0002 | 45 |
GO:0048024 | regulation of mRNA splicing, via spliceosome | 13/594 | 98/18670 | 0.0000 | 0.0003 | 13 |
GO:0050764 | regulation of phagocytosis | 13/594 | 98/18670 | 0.0000 | 0.0003 | 13 |
GO:0050657 | nucleic acid transport | 19/594 | 193/18670 | 0.0000 | 0.0003 | 19 |
GO:0050658 | RNA transport | 19/594 | 193/18670 | 0.0000 | 0.0003 | 19 |
GO:0016579 | protein deubiquitination | 24/594 | 283/18670 | 0.0000 | 0.0003 | 24 |
GO:0043062 | extracellular structure organization | 31/594 | 422/18670 | 0.0000 | 0.0003 | 31 |
GO:0071219 | cellular response to molecule of bacterial origin | 20/594 | 212/18670 | 0.0000 | 0.0003 | 20 |
GO:0071482 | cellular response to light stimulus | 15/594 | 129/18670 | 0.0000 | 0.0003 | 15 |
GO:1903037 | regulation of leukocyte cell-cell adhesion | 25/594 | 304/18670 | 0.0000 | 0.0003 | 25 |
GO:0043068 | positive regulation of programmed cell death | 43/594 | 680/18670 | 0.0000 | 0.0003 | 43 |
GO:0045785 | positive regulation of cell adhesion | 30/594 | 403/18670 | 0.0000 | 0.0003 | 30 |
GO:0072331 | signal transduction by p53 class mediator | 23/594 | 267/18670 | 0.0000 | 0.0003 | 23 |
GO:0006402 | mRNA catabolic process | 28/594 | 364/18670 | 0.0000 | 0.0003 | 28 |
GO:0006270 | DNA replication initiation | 8/594 | 37/18670 | 0.0000 | 0.0003 | 8 |
GO:0043039 | tRNA aminoacylation | 9/594 | 48/18670 | 0.0000 | 0.0003 | 9 |
GO:0048545 | response to steroid hormone | 29/594 | 385/18670 | 0.0000 | 0.0003 | 29 |
GO:0000302 | response to reactive oxygen species | 21/594 | 232/18670 | 0.0000 | 0.0003 | 21 |
GO:0042326 | negative regulation of phosphorylation | 33/594 | 468/18670 | 0.0000 | 0.0003 | 33 |
GO:1905330 | regulation of morphogenesis of an epithelium | 18/594 | 180/18670 | 0.0000 | 0.0003 | 18 |
GO:0010565 | regulation of cellular ketone metabolic process | 18/594 | 181/18670 | 0.0000 | 0.0004 | 18 |
GO:0043549 | regulation of kinase activity | 51/594 | 870/18670 | 0.0000 | 0.0004 | 51 |
GO:0070997 | neuron death | 27/594 | 348/18670 | 0.0000 | 0.0004 | 27 |
GO:0007420 | brain development | 45/594 | 733/18670 | 0.0000 | 0.0004 | 45 |
GO:0043038 | amino acid activation | 9/594 | 49/18670 | 0.0000 | 0.0004 | 9 |
GO:0051123 | RNA polymerase II preinitiation complex assembly | 7/594 | 28/18670 | 0.0000 | 0.0004 | 7 |
GO:0051095 | regulation of helicase activity | 5/594 | 12/18670 | 0.0000 | 0.0004 | 5 |
GO:0045787 | positive regulation of cell cycle | 29/594 | 389/18670 | 0.0000 | 0.0004 | 29 |
GO:0071241 | cellular response to inorganic substance | 20/594 | 217/18670 | 0.0000 | 0.0004 | 20 |
GO:0046651 | lymphocyte proliferation | 23/594 | 272/18670 | 0.0000 | 0.0004 | 23 |
GO:0071826 | ribonucleoprotein complex subunit organization | 24/594 | 291/18670 | 0.0000 | 0.0004 | 24 |
GO:0006979 | response to oxidative stress | 32/594 | 451/18670 | 0.0000 | 0.0004 | 32 |
GO:0002562 | somatic diversification of immune receptors via germline recombination within a single locus | 10/594 | 62/18670 | 0.0000 | 0.0004 | 10 |
GO:0016444 | somatic cell DNA recombination | 10/594 | 62/18670 | 0.0000 | 0.0004 | 10 |
GO:0032922 | circadian regulation of gene expression | 10/594 | 62/18670 | 0.0000 | 0.0004 | 10 |
GO:0032943 | mononuclear cell proliferation | 23/594 | 274/18670 | 0.0000 | 0.0004 | 23 |
GO:1901998 | toxin transport | 8/594 | 39/18670 | 0.0000 | 0.0004 | 8 |
GO:0050852 | T cell receptor signaling pathway | 19/594 | 202/18670 | 0.0000 | 0.0004 | 19 |
GO:0009416 | response to light stimulus | 25/594 | 314/18670 | 0.0000 | 0.0005 | 25 |
GO:0051962 | positive regulation of nervous system development | 36/594 | 541/18670 | 0.0000 | 0.0005 | 36 |
GO:0048511 | rhythmic process | 24/594 | 295/18670 | 0.0000 | 0.0005 | 24 |
GO:0071407 | cellular response to organic cyclic compound | 36/594 | 542/18670 | 0.0000 | 0.0005 | 36 |
GO:0022618 | ribonucleoprotein complex assembly | 23/594 | 277/18670 | 0.0000 | 0.0005 | 23 |
GO:0030099 | myeloid cell differentiation | 30/594 | 416/18670 | 0.0000 | 0.0005 | 30 |
GO:0050851 | antigen receptor-mediated signaling pathway | 25/594 | 316/18670 | 0.0000 | 0.0005 | 25 |
GO:0001816 | cytokine production | 47/594 | 790/18670 | 0.0000 | 0.0005 | 47 |
GO:0051223 | regulation of protein transport | 43/594 | 699/18670 | 0.0000 | 0.0005 | 43 |
GO:0032481 | positive regulation of type I interferon production | 11/594 | 77/18670 | 0.0000 | 0.0005 | 11 |
GO:0015931 | nucleobase-containing compound transport | 21/594 | 241/18670 | 0.0000 | 0.0005 | 21 |
GO:0007159 | leukocyte cell-cell adhesion | 26/594 | 337/18670 | 0.0000 | 0.0005 | 26 |
GO:0071222 | cellular response to lipopolysaccharide | 19/594 | 205/18670 | 0.0000 | 0.0005 | 19 |
GO:0043902 | positive regulation of multi-organism process | 18/594 | 188/18670 | 0.0000 | 0.0005 | 18 |
GO:0070646 | protein modification by small protein removal | 24/594 | 299/18670 | 0.0000 | 0.0006 | 24 |
GO:0050865 | regulation of cell activation | 39/594 | 614/18670 | 0.0000 | 0.0006 | 39 |
GO:0048524 | positive regulation of viral process | 13/594 | 107/18670 | 0.0000 | 0.0006 | 13 |
GO:0098781 | ncRNA transcription | 13/594 | 107/18670 | 0.0000 | 0.0006 | 13 |
GO:0070317 | negative regulation of G0 to G1 transition | 8/594 | 41/18670 | 0.0000 | 0.0006 | 8 |
GO:0090087 | regulation of peptide transport | 44/594 | 729/18670 | 0.0000 | 0.0006 | 44 |
GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 27/594 | 361/18670 | 0.0000 | 0.0006 | 27 |
GO:0007623 | circadian rhythm | 19/594 | 208/18670 | 0.0000 | 0.0006 | 19 |
GO:0060322 | head development | 46/594 | 776/18670 | 0.0000 | 0.0006 | 46 |
GO:0034976 | response to endoplasmic reticulum stress | 23/594 | 285/18670 | 0.0000 | 0.0007 | 23 |
GO:0032479 | regulation of type I interferon production | 14/594 | 126/18670 | 0.0000 | 0.0008 | 14 |
GO:0032069 | regulation of nuclease activity | 6/594 | 22/18670 | 0.0000 | 0.0008 | 6 |
GO:0031056 | regulation of histone modification | 15/594 | 143/18670 | 0.0001 | 0.0008 | 15 |
GO:0030198 | extracellular matrix organization | 27/594 | 368/18670 | 0.0001 | 0.0008 | 27 |
GO:2000377 | regulation of reactive oxygen species metabolic process | 18/594 | 195/18670 | 0.0001 | 0.0008 | 18 |
GO:0051347 | positive regulation of transferase activity | 40/594 | 649/18670 | 0.0001 | 0.0009 | 40 |
GO:0034644 | cellular response to UV | 11/594 | 82/18670 | 0.0001 | 0.0009 | 11 |
GO:0006354 | DNA-templated transcription, elongation | 13/594 | 112/18670 | 0.0001 | 0.0009 | 13 |
GO:0032606 | type I interferon production | 14/594 | 128/18670 | 0.0001 | 0.0009 | 14 |
GO:0044089 | positive regulation of cellular component biogenesis | 35/594 | 540/18670 | 0.0001 | 0.0009 | 35 |
GO:0045859 | regulation of protein kinase activity | 46/594 | 792/18670 | 0.0001 | 0.0010 | 46 |
GO:0010499 | proteasomal ubiquitin-independent protein catabolic process | 6/594 | 23/18670 | 0.0001 | 0.0010 | 6 |
GO:2001251 | negative regulation of chromosome organization | 15/594 | 146/18670 | 0.0001 | 0.0010 | 15 |
GO:0051170 | import into nucleus | 16/594 | 163/18670 | 0.0001 | 0.0010 | 16 |
GO:0032870 | cellular response to hormone stimulus | 42/594 | 701/18670 | 0.0001 | 0.0010 | 42 |
GO:1901214 | regulation of neuron death | 24/594 | 313/18670 | 0.0001 | 0.0011 | 24 |
GO:0006368 | transcription elongation from RNA polymerase II promoter | 11/594 | 84/18670 | 0.0001 | 0.0011 | 11 |
GO:0035966 | response to topologically incorrect protein | 18/594 | 199/18670 | 0.0001 | 0.0011 | 18 |
GO:0050863 | regulation of T cell activation | 24/594 | 314/18670 | 0.0001 | 0.0011 | 24 |
GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 19/594 | 218/18670 | 0.0001 | 0.0011 | 19 |
GO:0033151 | V(D)J recombination | 5/594 | 15/18670 | 0.0001 | 0.0011 | 5 |
GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly | 5/594 | 15/18670 | 0.0001 | 0.0011 | 5 |
GO:1902969 | mitotic DNA replication | 5/594 | 15/18670 | 0.0001 | 0.0011 | 5 |
GO:0070316 | regulation of G0 to G1 transition | 8/594 | 45/18670 | 0.0001 | 0.0011 | 8 |
GO:0072594 | establishment of protein localization to organelle | 35/594 | 549/18670 | 0.0001 | 0.0012 | 35 |
GO:0007569 | cell aging | 13/594 | 116/18670 | 0.0001 | 0.0012 | 13 |
GO:0043687 | post-translational protein modification | 26/594 | 361/18670 | 0.0001 | 0.0015 | 26 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 10/594 | 73/18670 | 0.0001 | 0.0015 | 10 |
GO:0038095 | Fc-epsilon receptor signaling pathway | 16/594 | 169/18670 | 0.0001 | 0.0015 | 16 |
GO:0045023 | G0 to G1 transition | 8/594 | 47/18670 | 0.0001 | 0.0015 | 8 |
GO:0061614 | pri-miRNA transcription by RNA polymerase II | 8/594 | 47/18670 | 0.0001 | 0.0015 | 8 |
GO:0009266 | response to temperature stimulus | 20/594 | 243/18670 | 0.0001 | 0.0015 | 20 |
GO:0001101 | response to acid chemical | 25/594 | 343/18670 | 0.0001 | 0.0016 | 25 |
GO:0045807 | positive regulation of endocytosis | 15/594 | 153/18670 | 0.0001 | 0.0016 | 15 |
GO:0002009 | morphogenesis of an epithelium | 34/594 | 537/18670 | 0.0001 | 0.0017 | 34 |
GO:0002200 | somatic diversification of immune receptors | 10/594 | 75/18670 | 0.0001 | 0.0018 | 10 |
GO:0008584 | male gonad development | 14/594 | 138/18670 | 0.0001 | 0.0019 | 14 |
GO:0097237 | cellular response to toxic substance | 20/594 | 247/18670 | 0.0001 | 0.0019 | 20 |
GO:0019216 | regulation of lipid metabolic process | 28/594 | 410/18670 | 0.0001 | 0.0019 | 28 |
GO:0040007 | growth | 53/594 | 986/18670 | 0.0001 | 0.0019 | 53 |
GO:0008015 | blood circulation | 34/594 | 541/18670 | 0.0001 | 0.0019 | 34 |
GO:0046677 | response to antibiotic | 24/594 | 327/18670 | 0.0001 | 0.0019 | 24 |
GO:1903409 | reactive oxygen species biosynthetic process | 13/594 | 122/18670 | 0.0001 | 0.0020 | 13 |
GO:0042060 | wound healing | 35/594 | 564/18670 | 0.0001 | 0.0020 | 35 |
GO:0097529 | myeloid leukocyte migration | 18/594 | 210/18670 | 0.0001 | 0.0020 | 18 |
GO:0044774 | mitotic DNA integrity checkpoint | 12/594 | 106/18670 | 0.0001 | 0.0020 | 12 |
GO:0006302 | double-strand break repair | 20/594 | 248/18670 | 0.0001 | 0.0020 | 20 |
GO:1901652 | response to peptide | 33/594 | 520/18670 | 0.0001 | 0.0020 | 33 |
GO:0006220 | pyrimidine nucleotide metabolic process | 9/594 | 62/18670 | 0.0001 | 0.0020 | 9 |
GO:0016571 | histone methylation | 14/594 | 139/18670 | 0.0001 | 0.0020 | 14 |
GO:0046546 | development of primary male sexual characteristics | 14/594 | 139/18670 | 0.0001 | 0.0020 | 14 |
GO:0019058 | viral life cycle | 24/594 | 328/18670 | 0.0001 | 0.0020 | 24 |
GO:2000142 | regulation of DNA-templated transcription, initiation | 7/594 | 37/18670 | 0.0001 | 0.0020 | 7 |
GO:0031570 | DNA integrity checkpoint | 15/594 | 157/18670 | 0.0002 | 0.0021 | 15 |
GO:0050878 | regulation of body fluid levels | 32/594 | 501/18670 | 0.0002 | 0.0022 | 32 |
GO:0051168 | nuclear export | 17/594 | 194/18670 | 0.0002 | 0.0022 | 17 |
GO:0006986 | response to unfolded protein | 16/594 | 176/18670 | 0.0002 | 0.0022 | 16 |
GO:0032873 | negative regulation of stress-activated MAPK cascade | 8/594 | 50/18670 | 0.0002 | 0.0023 | 8 |
GO:0070303 | negative regulation of stress-activated protein kinase signaling cascade | 8/594 | 50/18670 | 0.0002 | 0.0023 | 8 |
GO:0002449 | lymphocyte mediated immunity | 25/594 | 352/18670 | 0.0002 | 0.0023 | 25 |
GO:0071356 | cellular response to tumor necrosis factor | 22/594 | 291/18670 | 0.0002 | 0.0023 | 22 |
GO:0098727 | maintenance of cell number | 15/594 | 159/18670 | 0.0002 | 0.0023 | 15 |
GO:0034612 | response to tumor necrosis factor | 23/594 | 312/18670 | 0.0002 | 0.0024 | 23 |
GO:0009161 | ribonucleoside monophosphate metabolic process | 25/594 | 354/18670 | 0.0002 | 0.0024 | 25 |
GO:0046782 | regulation of viral transcription | 9/594 | 64/18670 | 0.0002 | 0.0024 | 9 |
GO:0009157 | deoxyribonucleoside monophosphate biosynthetic process | 4/594 | 10/18670 | 0.0002 | 0.0024 | 4 |
GO:0110096 | cellular response to aldehyde | 4/594 | 10/18670 | 0.0002 | 0.0024 | 4 |
GO:0055114 | oxidation-reduction process | 53/594 | 999/18670 | 0.0002 | 0.0025 | 53 |
GO:0048146 | positive regulation of fibroblast proliferation | 8/594 | 51/18670 | 0.0002 | 0.0025 | 8 |
GO:0097366 | response to bronchodilator | 8/594 | 51/18670 | 0.0002 | 0.0025 | 8 |
GO:0003013 | circulatory system process | 34/594 | 551/18670 | 0.0002 | 0.0025 | 34 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 28/594 | 419/18670 | 0.0002 | 0.0025 | 28 |
GO:0010952 | positive regulation of peptidase activity | 17/594 | 197/18670 | 0.0002 | 0.0026 | 17 |
GO:1903312 | negative regulation of mRNA metabolic process | 10/594 | 79/18670 | 0.0002 | 0.0026 | 10 |
GO:0000075 | cell cycle checkpoint | 18/594 | 216/18670 | 0.0002 | 0.0026 | 18 |
GO:0006479 | protein methylation | 16/594 | 179/18670 | 0.0002 | 0.0026 | 16 |
GO:0008213 | protein alkylation | 16/594 | 179/18670 | 0.0002 | 0.0026 | 16 |
GO:0060284 | regulation of cell development | 51/594 | 953/18670 | 0.0002 | 0.0026 | 51 |
GO:0006935 | chemotaxis | 38/594 | 644/18670 | 0.0002 | 0.0026 | 38 |
GO:0022409 | positive regulation of cell-cell adhesion | 20/594 | 255/18670 | 0.0002 | 0.0026 | 20 |
GO:0050686 | negative regulation of mRNA processing | 6/594 | 28/18670 | 0.0002 | 0.0027 | 6 |
GO:0060260 | regulation of transcription initiation from RNA polymerase II promoter | 6/594 | 28/18670 | 0.0002 | 0.0027 | 6 |
GO:0071346 | cellular response to interferon-gamma | 16/594 | 180/18670 | 0.0002 | 0.0027 | 16 |
GO:0031960 | response to corticosteroid | 15/594 | 162/18670 | 0.0002 | 0.0027 | 15 |
GO:0042330 | taxis | 38/594 | 646/18670 | 0.0002 | 0.0028 | 38 |
GO:0016447 | somatic recombination of immunoglobulin gene segments | 8/594 | 52/18670 | 0.0002 | 0.0028 | 8 |
GO:0034341 | response to interferon-gamma | 17/594 | 199/18670 | 0.0002 | 0.0028 | 17 |
GO:0048729 | tissue morphogenesis | 39/594 | 670/18670 | 0.0002 | 0.0028 | 39 |
GO:0032386 | regulation of intracellular transport | 28/594 | 423/18670 | 0.0002 | 0.0029 | 28 |
GO:0002285 | lymphocyte activation involved in immune response | 16/594 | 181/18670 | 0.0002 | 0.0029 | 16 |
GO:0043254 | regulation of protein complex assembly | 30/594 | 467/18670 | 0.0002 | 0.0029 | 30 |
GO:0042176 | regulation of protein catabolic process | 26/594 | 381/18670 | 0.0002 | 0.0029 | 26 |
GO:0097327 | response to antineoplastic agent | 11/594 | 96/18670 | 0.0002 | 0.0029 | 11 |
GO:1990823 | response to leukemia inhibitory factor | 11/594 | 96/18670 | 0.0002 | 0.0029 | 11 |
GO:1990830 | cellular response to leukemia inhibitory factor | 11/594 | 96/18670 | 0.0002 | 0.0029 | 11 |
GO:0051384 | response to glucocorticoid | 14/594 | 146/18670 | 0.0002 | 0.0030 | 14 |
GO:0006338 | chromatin remodeling | 16/594 | 182/18670 | 0.0002 | 0.0030 | 16 |
GO:0008217 | regulation of blood pressure | 16/594 | 182/18670 | 0.0002 | 0.0030 | 16 |
GO:0007599 | hemostasis | 24/594 | 341/18670 | 0.0003 | 0.0032 | 24 |
GO:0090263 | positive regulation of canonical Wnt signaling pathway | 14/594 | 147/18670 | 0.0003 | 0.0032 | 14 |
GO:0048709 | oligodendrocyte differentiation | 11/594 | 97/18670 | 0.0003 | 0.0032 | 11 |
GO:0046390 | ribose phosphate biosynthetic process | 22/594 | 300/18670 | 0.0003 | 0.0032 | 22 |
GO:0007093 | mitotic cell cycle checkpoint | 15/594 | 165/18670 | 0.0003 | 0.0032 | 15 |
GO:0050870 | positive regulation of T cell activation | 17/594 | 202/18670 | 0.0003 | 0.0032 | 17 |
GO:0045861 | negative regulation of proteolysis | 25/594 | 363/18670 | 0.0003 | 0.0033 | 25 |
GO:0042098 | T cell proliferation | 16/594 | 184/18670 | 0.0003 | 0.0033 | 16 |
GO:1901653 | cellular response to peptide | 26/594 | 385/18670 | 0.0003 | 0.0033 | 26 |
GO:0034968 | histone lysine methylation | 12/594 | 114/18670 | 0.0003 | 0.0033 | 12 |
GO:0010038 | response to metal ion | 25/594 | 364/18670 | 0.0003 | 0.0033 | 25 |
GO:0050434 | positive regulation of viral transcription | 7/594 | 41/18670 | 0.0003 | 0.0033 | 7 |
GO:1902893 | regulation of pri-miRNA transcription by RNA polymerase II | 7/594 | 41/18670 | 0.0003 | 0.0033 | 7 |
GO:0000727 | double-strand break repair via break-induced replication | 4/594 | 11/18670 | 0.0003 | 0.0033 | 4 |
GO:0019042 | viral latency | 4/594 | 11/18670 | 0.0003 | 0.0033 | 4 |
GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly | 4/594 | 11/18670 | 0.0003 | 0.0033 | 4 |
GO:0046185 | aldehyde catabolic process | 4/594 | 11/18670 | 0.0003 | 0.0033 | 4 |
GO:0090329 | regulation of DNA-dependent DNA replication | 8/594 | 54/18670 | 0.0003 | 0.0034 | 8 |
GO:1902275 | regulation of chromatin organization | 16/594 | 185/18670 | 0.0003 | 0.0035 | 16 |
GO:0050767 | regulation of neurogenesis | 45/594 | 822/18670 | 0.0003 | 0.0035 | 45 |
GO:0033209 | tumor necrosis factor-mediated signaling pathway | 15/594 | 167/18670 | 0.0003 | 0.0035 | 15 |
GO:0006970 | response to osmotic stress | 10/594 | 83/18670 | 0.0003 | 0.0035 | 10 |
GO:1903829 | positive regulation of cellular protein localization | 23/594 | 324/18670 | 0.0003 | 0.0036 | 23 |
GO:0006954 | inflammatory response | 46/594 | 848/18670 | 0.0003 | 0.0036 | 46 |
GO:0030595 | leukocyte chemotaxis | 18/594 | 224/18670 | 0.0003 | 0.0036 | 18 |
GO:0072593 | reactive oxygen species metabolic process | 21/594 | 284/18670 | 0.0003 | 0.0037 | 21 |
GO:0031330 | negative regulation of cellular catabolic process | 20/594 | 264/18670 | 0.0003 | 0.0037 | 20 |
GO:0050900 | leukocyte migration | 31/594 | 499/18670 | 0.0003 | 0.0038 | 31 |
GO:0006304 | DNA modification | 12/594 | 116/18670 | 0.0003 | 0.0038 | 12 |
GO:1900180 | regulation of protein localization to nucleus | 12/594 | 116/18670 | 0.0003 | 0.0038 | 12 |
GO:0009615 | response to virus | 23/594 | 326/18670 | 0.0003 | 0.0038 | 23 |
GO:0002320 | lymphoid progenitor cell differentiation | 5/594 | 20/18670 | 0.0003 | 0.0038 | 5 |
GO:0006271 | DNA strand elongation involved in DNA replication | 5/594 | 20/18670 | 0.0003 | 0.0038 | 5 |
GO:0016137 | glycoside metabolic process | 5/594 | 20/18670 | 0.0003 | 0.0038 | 5 |
GO:0048872 | homeostasis of number of cells | 19/594 | 246/18670 | 0.0004 | 0.0040 | 19 |
GO:0033077 | T cell differentiation in thymus | 9/594 | 70/18670 | 0.0004 | 0.0042 | 9 |
GO:0002697 | regulation of immune effector process | 29/594 | 458/18670 | 0.0004 | 0.0042 | 29 |
GO:1903362 | regulation of cellular protein catabolic process | 19/594 | 247/18670 | 0.0004 | 0.0042 | 19 |
GO:0010543 | regulation of platelet activation | 6/594 | 31/18670 | 0.0004 | 0.0043 | 6 |
GO:1902895 | positive regulation of pri-miRNA transcription by RNA polymerase II | 6/594 | 31/18670 | 0.0004 | 0.0043 | 6 |
GO:0031334 | positive regulation of protein complex assembly | 20/594 | 268/18670 | 0.0004 | 0.0044 | 20 |
GO:0006303 | double-strand break repair via nonhomologous end joining | 10/594 | 86/18670 | 0.0004 | 0.0045 | 10 |
GO:0042113 | B cell activation | 22/594 | 310/18670 | 0.0004 | 0.0046 | 22 |
GO:0006323 | DNA packaging | 17/594 | 210/18670 | 0.0004 | 0.0047 | 17 |
GO:0072431 | signal transduction involved in mitotic G1 DNA damage checkpoint | 8/594 | 57/18670 | 0.0004 | 0.0047 | 8 |
GO:1902400 | intracellular signal transduction involved in G1 DNA damage checkpoint | 8/594 | 57/18670 | 0.0004 | 0.0047 | 8 |
GO:0071383 | cellular response to steroid hormone stimulus | 19/594 | 250/18670 | 0.0004 | 0.0048 | 19 |
GO:0048871 | multicellular organismal homeostasis | 30/594 | 485/18670 | 0.0004 | 0.0048 | 30 |
GO:0001659 | temperature homeostasis | 15/594 | 173/18670 | 0.0004 | 0.0048 | 15 |
GO:0009060 | aerobic respiration | 10/594 | 87/18670 | 0.0004 | 0.0049 | 10 |
GO:0009991 | response to extracellular stimulus | 32/594 | 531/18670 | 0.0004 | 0.0049 | 32 |
GO:0035019 | somatic stem cell population maintenance | 9/594 | 72/18670 | 0.0004 | 0.0050 | 9 |
GO:0001819 | positive regulation of cytokine production | 29/594 | 464/18670 | 0.0005 | 0.0050 | 29 |
GO:0043086 | negative regulation of catalytic activity | 44/594 | 815/18670 | 0.0005 | 0.0050 | 44 |
GO:0072522 | purine-containing compound biosynthetic process | 22/594 | 313/18670 | 0.0005 | 0.0051 | 22 |
GO:1902105 | regulation of leukocyte differentiation | 20/594 | 272/18670 | 0.0005 | 0.0052 | 20 |
GO:1903557 | positive regulation of tumor necrosis factor superfamily cytokine production | 10/594 | 88/18670 | 0.0005 | 0.0052 | 10 |
GO:0030968 | endoplasmic reticulum unfolded protein response | 12/594 | 121/18670 | 0.0005 | 0.0053 | 12 |
GO:0048589 | developmental growth | 38/594 | 674/18670 | 0.0005 | 0.0054 | 38 |
GO:0019827 | stem cell population maintenance | 14/594 | 157/18670 | 0.0005 | 0.0055 | 14 |
GO:0007596 | blood coagulation | 23/594 | 336/18670 | 0.0005 | 0.0055 | 23 |
GO:2001020 | regulation of response to DNA damage stimulus | 17/594 | 214/18670 | 0.0005 | 0.0056 | 17 |
GO:0019079 | viral genome replication | 12/594 | 122/18670 | 0.0005 | 0.0056 | 12 |
GO:0072413 | signal transduction involved in mitotic cell cycle checkpoint | 8/594 | 59/18670 | 0.0005 | 0.0057 | 8 |
GO:1902402 | signal transduction involved in mitotic DNA damage checkpoint | 8/594 | 59/18670 | 0.0005 | 0.0057 | 8 |
GO:1902403 | signal transduction involved in mitotic DNA integrity checkpoint | 8/594 | 59/18670 | 0.0005 | 0.0057 | 8 |
GO:0030851 | granulocyte differentiation | 6/594 | 33/18670 | 0.0005 | 0.0058 | 6 |
GO:0007063 | regulation of sister chromatid cohesion | 5/594 | 22/18670 | 0.0005 | 0.0058 | 5 |
GO:0070371 | ERK1 and ERK2 cascade | 22/594 | 317/18670 | 0.0005 | 0.0059 | 22 |
GO:0071900 | regulation of protein serine/threonine kinase activity | 31/594 | 515/18670 | 0.0006 | 0.0059 | 31 |
GO:0014015 | positive regulation of gliogenesis | 9/594 | 74/18670 | 0.0006 | 0.0059 | 9 |
GO:1900182 | positive regulation of protein localization to nucleus | 9/594 | 74/18670 | 0.0006 | 0.0059 | 9 |
GO:0031058 | positive regulation of histone modification | 10/594 | 90/18670 | 0.0006 | 0.0061 | 10 |
GO:0009162 | deoxyribonucleoside monophosphate metabolic process | 4/594 | 13/18670 | 0.0006 | 0.0061 | 4 |
GO:0009156 | ribonucleoside monophosphate biosynthetic process | 16/594 | 197/18670 | 0.0006 | 0.0062 | 16 |
GO:0090090 | negative regulation of canonical Wnt signaling pathway | 15/594 | 178/18670 | 0.0006 | 0.0062 | 15 |
GO:0009167 | purine ribonucleoside monophosphate metabolic process | 23/594 | 340/18670 | 0.0006 | 0.0062 | 23 |
GO:0045576 | mast cell activation | 8/594 | 60/18670 | 0.0006 | 0.0063 | 8 |
GO:0008406 | gonad development | 17/594 | 217/18670 | 0.0006 | 0.0063 | 17 |
GO:0009141 | nucleoside triphosphate metabolic process | 24/594 | 362/18670 | 0.0006 | 0.0063 | 24 |
GO:0046661 | male sex differentiation | 14/594 | 160/18670 | 0.0006 | 0.0063 | 14 |
GO:0009126 | purine nucleoside monophosphate metabolic process | 23/594 | 341/18670 | 0.0006 | 0.0064 | 23 |
GO:0006611 | protein export from nucleus | 15/594 | 179/18670 | 0.0006 | 0.0064 | 15 |
GO:0030177 | positive regulation of Wnt signaling pathway | 15/594 | 179/18670 | 0.0006 | 0.0064 | 15 |
GO:0010001 | glial cell differentiation | 17/594 | 218/18670 | 0.0006 | 0.0066 | 17 |
GO:0042692 | muscle cell differentiation | 25/594 | 385/18670 | 0.0006 | 0.0066 | 25 |
GO:0050817 | coagulation | 23/594 | 342/18670 | 0.0006 | 0.0066 | 23 |
GO:0070372 | regulation of ERK1 and ERK2 cascade | 21/594 | 300/18670 | 0.0007 | 0.0067 | 21 |
GO:0051402 | neuron apoptotic process | 18/594 | 239/18670 | 0.0007 | 0.0068 | 18 |
GO:0070302 | regulation of stress-activated protein kinase signaling cascade | 18/594 | 239/18670 | 0.0007 | 0.0068 | 18 |
GO:2000116 | regulation of cysteine-type endopeptidase activity | 18/594 | 239/18670 | 0.0007 | 0.0068 | 18 |
GO:0007064 | mitotic sister chromatid cohesion | 5/594 | 23/18670 | 0.0007 | 0.0068 | 5 |
GO:0048714 | positive regulation of oligodendrocyte differentiation | 5/594 | 23/18670 | 0.0007 | 0.0068 | 5 |
GO:2000637 | positive regulation of gene silencing by miRNA | 5/594 | 23/18670 | 0.0007 | 0.0068 | 5 |
GO:0000380 | alternative mRNA splicing, via spliceosome | 9/594 | 76/18670 | 0.0007 | 0.0068 | 9 |
GO:0048608 | reproductive structure development | 27/594 | 431/18670 | 0.0007 | 0.0069 | 27 |
GO:0010498 | proteasomal protein catabolic process | 29/594 | 477/18670 | 0.0007 | 0.0071 | 29 |
GO:0009166 | nucleotide catabolic process | 15/594 | 182/18670 | 0.0007 | 0.0075 | 15 |
GO:0042593 | glucose homeostasis | 18/594 | 241/18670 | 0.0007 | 0.0075 | 18 |
GO:0002694 | regulation of leukocyte activation | 33/594 | 571/18670 | 0.0007 | 0.0075 | 33 |
GO:0006101 | citrate metabolic process | 6/594 | 35/18670 | 0.0007 | 0.0075 | 6 |
GO:0006369 | termination of RNA polymerase II transcription | 6/594 | 35/18670 | 0.0007 | 0.0075 | 6 |
GO:0009262 | deoxyribonucleotide metabolic process | 6/594 | 35/18670 | 0.0007 | 0.0075 | 6 |
GO:0061458 | reproductive system development | 27/594 | 434/18670 | 0.0008 | 0.0075 | 27 |
GO:0032648 | regulation of interferon-beta production | 7/594 | 48/18670 | 0.0008 | 0.0075 | 7 |
GO:0051972 | regulation of telomerase activity | 7/594 | 48/18670 | 0.0008 | 0.0075 | 7 |
GO:0061647 | histone H3-K9 modification | 7/594 | 48/18670 | 0.0008 | 0.0075 | 7 |
GO:1903727 | positive regulation of phospholipid metabolic process | 7/594 | 48/18670 | 0.0008 | 0.0075 | 7 |
GO:0010466 | negative regulation of peptidase activity | 19/594 | 262/18670 | 0.0008 | 0.0075 | 19 |
GO:0006412 | translation | 39/594 | 714/18670 | 0.0008 | 0.0075 | 39 |
GO:0033500 | carbohydrate homeostasis | 18/594 | 242/18670 | 0.0008 | 0.0076 | 18 |
GO:0035821 | modification of morphology or physiology of other organism | 14/594 | 164/18670 | 0.0008 | 0.0076 | 14 |
GO:0043043 | peptide biosynthetic process | 40/594 | 739/18670 | 0.0008 | 0.0077 | 40 |
GO:0061136 | regulation of proteasomal protein catabolic process | 15/594 | 183/18670 | 0.0008 | 0.0077 | 15 |
GO:0033674 | positive regulation of kinase activity | 33/594 | 573/18670 | 0.0008 | 0.0078 | 33 |
GO:0000726 | non-recombinational repair | 10/594 | 94/18670 | 0.0008 | 0.0079 | 10 |
GO:0044728 | DNA methylation or demethylation | 10/594 | 94/18670 | 0.0008 | 0.0079 | 10 |
GO:0045137 | development of primary sexual characteristics | 17/594 | 223/18670 | 0.0008 | 0.0080 | 17 |
GO:1904019 | epithelial cell apoptotic process | 11/594 | 111/18670 | 0.0008 | 0.0080 | 11 |
GO:0048017 | inositol lipid-mediated signaling | 15/594 | 184/18670 | 0.0008 | 0.0080 | 15 |
GO:0060148 | positive regulation of posttranscriptional gene silencing | 5/594 | 24/18670 | 0.0008 | 0.0080 | 5 |
GO:0098609 | cell-cell adhesion | 44/594 | 839/18670 | 0.0008 | 0.0080 | 44 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 8/594 | 63/18670 | 0.0008 | 0.0080 | 8 |
GO:0044819 | mitotic G1/S transition checkpoint | 8/594 | 63/18670 | 0.0008 | 0.0080 | 8 |
GO:0015980 | energy derivation by oxidation of organic compounds | 20/594 | 285/18670 | 0.0008 | 0.0081 | 20 |
GO:0002262 | myeloid cell homeostasis | 13/594 | 147/18670 | 0.0009 | 0.0082 | 13 |
GO:1901657 | glycosyl compound metabolic process | 13/594 | 147/18670 | 0.0009 | 0.0082 | 13 |
GO:0018022 | peptidyl-lysine methylation | 12/594 | 129/18670 | 0.0009 | 0.0082 | 12 |
GO:0097435 | supramolecular fiber organization | 37/594 | 671/18670 | 0.0009 | 0.0083 | 37 |
GO:1903708 | positive regulation of hemopoiesis | 15/594 | 185/18670 | 0.0009 | 0.0083 | 15 |
GO:0051973 | positive regulation of telomerase activity | 6/594 | 36/18670 | 0.0009 | 0.0083 | 6 |
GO:0045069 | regulation of viral genome replication | 10/594 | 95/18670 | 0.0009 | 0.0083 | 10 |
GO:0051651 | maintenance of location in cell | 10/594 | 95/18670 | 0.0009 | 0.0083 | 10 |
GO:0002440 | production of molecular mediator of immune response | 20/594 | 286/18670 | 0.0009 | 0.0083 | 20 |
GO:0050867 | positive regulation of cell activation | 25/594 | 394/18670 | 0.0009 | 0.0084 | 25 |
GO:0051817 | modification of morphology or physiology of other organism involved in symbiotic interaction | 11/594 | 112/18670 | 0.0009 | 0.0084 | 11 |
GO:0019693 | ribose phosphate metabolic process | 33/594 | 577/18670 | 0.0009 | 0.0084 | 33 |
GO:0030193 | regulation of blood coagulation | 9/594 | 79/18670 | 0.0009 | 0.0084 | 9 |
GO:0022900 | electron transport chain | 15/594 | 186/18670 | 0.0009 | 0.0086 | 15 |
GO:0016445 | somatic diversification of immunoglobulins | 8/594 | 64/18670 | 0.0009 | 0.0086 | 8 |
GO:0036498 | IRE1-mediated unfolded protein response | 8/594 | 64/18670 | 0.0009 | 0.0086 | 8 |
GO:0043550 | regulation of lipid kinase activity | 8/594 | 64/18670 | 0.0009 | 0.0086 | 8 |
GO:0044783 | G1 DNA damage checkpoint | 8/594 | 64/18670 | 0.0009 | 0.0086 | 8 |
GO:2000378 | negative regulation of reactive oxygen species metabolic process | 8/594 | 64/18670 | 0.0009 | 0.0086 | 8 |
GO:0045860 | positive regulation of protein kinase activity | 31/594 | 532/18670 | 0.0009 | 0.0087 | 31 |
GO:0034404 | nucleobase-containing small molecule biosynthetic process | 17/594 | 226/18670 | 0.0009 | 0.0088 | 17 |
GO:0043200 | response to amino acid | 11/594 | 113/18670 | 0.0010 | 0.0088 | 11 |
GO:0060964 | regulation of gene silencing by miRNA | 11/594 | 113/18670 | 0.0010 | 0.0088 | 11 |
GO:0009267 | cellular response to starvation | 13/594 | 149/18670 | 0.0010 | 0.0089 | 13 |
GO:0032787 | monocarboxylic acid metabolic process | 36/594 | 651/18670 | 0.0010 | 0.0089 | 36 |
GO:0032608 | interferon-beta production | 7/594 | 50/18670 | 0.0010 | 0.0089 | 7 |
GO:1900046 | regulation of hemostasis | 9/594 | 80/18670 | 0.0010 | 0.0090 | 9 |
GO:0098754 | detoxification | 12/594 | 131/18670 | 0.0010 | 0.0090 | 12 |
GO:0051604 | protein maturation | 25/594 | 397/18670 | 0.0010 | 0.0090 | 25 |
GO:0031668 | cellular response to extracellular stimulus | 19/594 | 268/18670 | 0.0010 | 0.0091 | 19 |
GO:0007339 | binding of sperm to zona pellucida | 6/594 | 37/18670 | 0.0010 | 0.0092 | 6 |
GO:0051567 | histone H3-K9 methylation | 6/594 | 37/18670 | 0.0010 | 0.0092 | 6 |
GO:0031060 | regulation of histone methylation | 8/594 | 65/18670 | 0.0010 | 0.0093 | 8 |
GO:1901292 | nucleoside phosphate catabolic process | 15/594 | 188/18670 | 0.0010 | 0.0093 | 15 |
GO:0051346 | negative regulation of hydrolase activity | 28/594 | 466/18670 | 0.0010 | 0.0094 | 28 |
GO:0030518 | intracellular steroid hormone receptor signaling pathway | 12/594 | 132/18670 | 0.0010 | 0.0094 | 12 |
GO:0009415 | response to water | 4/594 | 15/18670 | 0.0010 | 0.0094 | 4 |
GO:0030812 | negative regulation of nucleotide catabolic process | 4/594 | 15/18670 | 0.0010 | 0.0094 | 4 |
GO:0034349 | glial cell apoptotic process | 4/594 | 15/18670 | 0.0010 | 0.0094 | 4 |
GO:0051198 | negative regulation of coenzyme metabolic process | 4/594 | 15/18670 | 0.0010 | 0.0094 | 4 |
GO:0000819 | sister chromatid segregation | 15/594 | 189/18670 | 0.0011 | 0.0097 | 15 |
GO:0006959 | humoral immune response | 23/594 | 356/18670 | 0.0011 | 0.0099 | 23 |
GO:0042770 | signal transduction in response to DNA damage | 12/594 | 133/18670 | 0.0011 | 0.0100 | 12 |
ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | Count |
---|---|---|---|---|---|---|
GO:0002366 | leukocyte activation involved in immune response | 60/300 | 707/18670 | 0.0000 | 0.0000 | 60 |
GO:0002263 | cell activation involved in immune response | 60/300 | 711/18670 | 0.0000 | 0.0000 | 60 |
GO:0002274 | myeloid leukocyte activation | 57/300 | 651/18670 | 0.0000 | 0.0000 | 57 |
GO:0036230 | granulocyte activation | 48/300 | 504/18670 | 0.0000 | 0.0000 | 48 |
GO:0042119 | neutrophil activation | 47/300 | 498/18670 | 0.0000 | 0.0000 | 47 |
GO:0043299 | leukocyte degranulation | 48/300 | 534/18670 | 0.0000 | 0.0000 | 48 |
GO:0006887 | exocytosis | 61/300 | 903/18670 | 0.0000 | 0.0000 | 61 |
GO:0043312 | neutrophil degranulation | 45/300 | 485/18670 | 0.0000 | 0.0000 | 45 |
GO:0002283 | neutrophil activation involved in immune response | 45/300 | 488/18670 | 0.0000 | 0.0000 | 45 |
GO:0002275 | myeloid cell activation involved in immune response | 47/300 | 544/18670 | 0.0000 | 0.0000 | 47 |
GO:0002446 | neutrophil mediated immunity | 45/300 | 499/18670 | 0.0000 | 0.0000 | 45 |
GO:0002444 | myeloid leukocyte mediated immunity | 47/300 | 551/18670 | 0.0000 | 0.0000 | 47 |
GO:0045055 | regulated exocytosis | 56/300 | 794/18670 | 0.0000 | 0.0000 | 56 |
GO:0002443 | leukocyte mediated immunity | 56/300 | 874/18670 | 0.0000 | 0.0000 | 56 |
GO:0019221 | cytokine-mediated signaling pathway | 46/300 | 798/18670 | 0.0000 | 0.0000 | 46 |
GO:0097190 | apoptotic signaling pathway | 38/300 | 602/18670 | 0.0000 | 0.0000 | 38 |
GO:2001233 | regulation of apoptotic signaling pathway | 30/300 | 406/18670 | 0.0000 | 0.0000 | 30 |
GO:0001816 | cytokine production | 42/300 | 790/18670 | 0.0000 | 0.0000 | 42 |
GO:0043066 | negative regulation of apoptotic process | 45/300 | 911/18670 | 0.0000 | 0.0000 | 45 |
GO:0043069 | negative regulation of programmed cell death | 45/300 | 932/18670 | 0.0000 | 0.0000 | 45 |
GO:0014070 | response to organic cyclic compound | 44/300 | 915/18670 | 0.0000 | 0.0000 | 44 |
GO:0050865 | regulation of cell activation | 35/300 | 614/18670 | 0.0000 | 0.0000 | 35 |
GO:0002520 | immune system development | 45/300 | 985/18670 | 0.0000 | 0.0000 | 45 |
GO:0048534 | hematopoietic or lymphoid organ development | 43/300 | 929/18670 | 0.0000 | 0.0000 | 43 |
GO:0001817 | regulation of cytokine production | 37/300 | 719/18670 | 0.0000 | 0.0000 | 37 |
GO:0032870 | cellular response to hormone stimulus | 36/300 | 701/18670 | 0.0000 | 0.0000 | 36 |
GO:0002285 | lymphocyte activation involved in immune response | 18/300 | 181/18670 | 0.0000 | 0.0000 | 18 |
GO:0002694 | regulation of leukocyte activation | 32/300 | 571/18670 | 0.0000 | 0.0000 | 32 |
GO:0030097 | hemopoiesis | 41/300 | 887/18670 | 0.0000 | 0.0000 | 41 |
GO:0010942 | positive regulation of cell death | 36/300 | 730/18670 | 0.0000 | 0.0000 | 36 |
GO:0001818 | negative regulation of cytokine production | 22/300 | 296/18670 | 0.0000 | 0.0000 | 22 |
GO:0043065 | positive regulation of apoptotic process | 34/300 | 672/18670 | 0.0000 | 0.0000 | 34 |
GO:0043068 | positive regulation of programmed cell death | 34/300 | 680/18670 | 0.0000 | 0.0000 | 34 |
GO:0050867 | positive regulation of cell activation | 25/300 | 394/18670 | 0.0000 | 0.0000 | 25 |
GO:2001234 | negative regulation of apoptotic signaling pathway | 19/300 | 230/18670 | 0.0000 | 0.0000 | 19 |
GO:0051050 | positive regulation of transport | 42/300 | 982/18670 | 0.0000 | 0.0000 | 42 |
GO:0002700 | regulation of production of molecular mediator of immune response | 15/300 | 139/18670 | 0.0000 | 0.0000 | 15 |
GO:0009725 | response to hormone | 42/300 | 987/18670 | 0.0000 | 0.0000 | 42 |
GO:0046649 | lymphocyte activation | 35/300 | 733/18670 | 0.0000 | 0.0000 | 35 |
GO:0010035 | response to inorganic substance | 30/300 | 562/18670 | 0.0000 | 0.0000 | 30 |
GO:0033993 | response to lipid | 40/300 | 923/18670 | 0.0000 | 0.0000 | 40 |
GO:0002521 | leukocyte differentiation | 28/300 | 515/18670 | 0.0000 | 0.0000 | 28 |
GO:1903047 | mitotic cell cycle process | 38/300 | 873/18670 | 0.0000 | 0.0000 | 38 |
GO:0044403 | symbiont process | 38/300 | 884/18670 | 0.0000 | 0.0000 | 38 |
GO:0071222 | cellular response to lipopolysaccharide | 17/300 | 205/18670 | 0.0000 | 0.0000 | 17 |
GO:0051098 | regulation of binding | 23/300 | 373/18670 | 0.0000 | 0.0000 | 23 |
GO:0023014 | signal transduction by protein phosphorylation | 40/300 | 969/18670 | 0.0000 | 0.0000 | 40 |
GO:0019725 | cellular homeostasis | 40/300 | 970/18670 | 0.0000 | 0.0000 | 40 |
GO:0044419 | interspecies interaction between organisms | 39/300 | 932/18670 | 0.0000 | 0.0000 | 39 |
GO:0070997 | neuron death | 22/300 | 348/18670 | 0.0000 | 0.0000 | 22 |
GO:0002696 | positive regulation of leukocyte activation | 23/300 | 380/18670 | 0.0000 | 0.0000 | 23 |
GO:1903706 | regulation of hemopoiesis | 26/300 | 475/18670 | 0.0000 | 0.0000 | 26 |
GO:0007568 | aging | 21/300 | 321/18670 | 0.0000 | 0.0000 | 21 |
GO:0071219 | cellular response to molecule of bacterial origin | 17/300 | 212/18670 | 0.0000 | 0.0000 | 17 |
GO:0016032 | viral process | 36/300 | 833/18670 | 0.0000 | 0.0000 | 36 |
GO:0030099 | myeloid cell differentiation | 24/300 | 416/18670 | 0.0000 | 0.0000 | 24 |
GO:0000122 | negative regulation of transcription by RNA polymerase II | 36/300 | 839/18670 | 0.0000 | 0.0000 | 36 |
GO:0030155 | regulation of cell adhesion | 32/300 | 691/18670 | 0.0000 | 0.0000 | 32 |
GO:0000165 | MAPK cascade | 39/300 | 958/18670 | 0.0000 | 0.0000 | 39 |
GO:0010243 | response to organonitrogen compound | 40/300 | 998/18670 | 0.0000 | 0.0000 | 40 |
GO:0032496 | response to lipopolysaccharide | 21/300 | 330/18670 | 0.0000 | 0.0000 | 21 |
GO:0007584 | response to nutrient | 17/300 | 219/18670 | 0.0000 | 0.0000 | 17 |
GO:0006954 | inflammatory response | 36/300 | 848/18670 | 0.0000 | 0.0000 | 36 |
GO:0010038 | response to metal ion | 22/300 | 364/18670 | 0.0000 | 0.0000 | 22 |
GO:0051338 | regulation of transferase activity | 39/300 | 972/18670 | 0.0000 | 0.0000 | 39 |
GO:0007159 | leukocyte cell-cell adhesion | 21/300 | 337/18670 | 0.0000 | 0.0000 | 21 |
GO:0002683 | negative regulation of immune system process | 25/300 | 463/18670 | 0.0000 | 0.0000 | 25 |
GO:0002576 | platelet degranulation | 13/300 | 128/18670 | 0.0000 | 0.0000 | 13 |
GO:0050778 | positive regulation of immune response | 37/300 | 902/18670 | 0.0000 | 0.0000 | 37 |
GO:0046916 | cellular transition metal ion homeostasis | 12/300 | 108/18670 | 0.0000 | 0.0000 | 12 |
GO:1901214 | regulation of neuron death | 20/300 | 313/18670 | 0.0000 | 0.0000 | 20 |
GO:0002237 | response to molecule of bacterial origin | 21/300 | 343/18670 | 0.0000 | 0.0000 | 21 |
GO:0040007 | growth | 39/300 | 986/18670 | 0.0000 | 0.0000 | 39 |
GO:0008284 | positive regulation of cell proliferation | 38/300 | 951/18670 | 0.0000 | 0.0000 | 38 |
GO:0097193 | intrinsic apoptotic signaling pathway | 19/300 | 289/18670 | 0.0000 | 0.0000 | 19 |
GO:0030003 | cellular cation homeostasis | 30/300 | 652/18670 | 0.0000 | 0.0000 | 30 |
GO:0007346 | regulation of mitotic cell cycle | 30/300 | 656/18670 | 0.0000 | 0.0000 | 30 |
GO:0071216 | cellular response to biotic stimulus | 17/300 | 236/18670 | 0.0000 | 0.0000 | 17 |
GO:0044772 | mitotic cell cycle phase transition | 28/300 | 588/18670 | 0.0000 | 0.0000 | 28 |
GO:0051249 | regulation of lymphocyte activation | 25/300 | 485/18670 | 0.0000 | 0.0000 | 25 |
GO:0006873 | cellular ion homeostasis | 30/300 | 665/18670 | 0.0000 | 0.0000 | 30 |
GO:0070661 | leukocyte proliferation | 19/300 | 298/18670 | 0.0000 | 0.0000 | 19 |
GO:0044770 | cell cycle phase transition | 29/300 | 631/18670 | 0.0000 | 0.0000 | 29 |
GO:0070482 | response to oxygen levels | 22/300 | 394/18670 | 0.0000 | 0.0000 | 22 |
GO:0032943 | mononuclear cell proliferation | 18/300 | 274/18670 | 0.0000 | 0.0000 | 18 |
GO:1902532 | negative regulation of intracellular signal transduction | 27/300 | 566/18670 | 0.0000 | 0.0000 | 27 |
GO:0051186 | cofactor metabolic process | 28/300 | 602/18670 | 0.0000 | 0.0000 | 28 |
GO:0001819 | positive regulation of cytokine production | 24/300 | 464/18670 | 0.0000 | 0.0000 | 24 |
GO:0050900 | leukocyte migration | 25/300 | 499/18670 | 0.0000 | 0.0000 | 25 |
GO:0055094 | response to lipoprotein particle | 7/300 | 32/18670 | 0.0000 | 0.0000 | 7 |
GO:0071901 | negative regulation of protein serine/threonine kinase activity | 13/300 | 145/18670 | 0.0000 | 0.0000 | 13 |
GO:1905477 | positive regulation of protein localization to membrane | 12/300 | 122/18670 | 0.0000 | 0.0000 | 12 |
GO:0071396 | cellular response to lipid | 28/300 | 610/18670 | 0.0000 | 0.0000 | 28 |
GO:0045637 | regulation of myeloid cell differentiation | 17/300 | 251/18670 | 0.0000 | 0.0000 | 17 |
GO:0002637 | regulation of immunoglobulin production | 9/300 | 63/18670 | 0.0000 | 0.0000 | 9 |
GO:2000379 | positive regulation of reactive oxygen species metabolic process | 11/300 | 102/18670 | 0.0000 | 0.0000 | 11 |
GO:0055080 | cation homeostasis | 31/300 | 730/18670 | 0.0000 | 0.0000 | 31 |
GO:1901990 | regulation of mitotic cell cycle phase transition | 23/300 | 444/18670 | 0.0000 | 0.0000 | 23 |
GO:0010507 | negative regulation of autophagy | 10/300 | 84/18670 | 0.0000 | 0.0000 | 10 |
GO:0071402 | cellular response to lipoprotein particle stimulus | 7/300 | 34/18670 | 0.0000 | 0.0000 | 7 |
GO:1901987 | regulation of cell cycle phase transition | 24/300 | 480/18670 | 0.0000 | 0.0000 | 24 |
GO:0071900 | regulation of protein serine/threonine kinase activity | 25/300 | 515/18670 | 0.0000 | 0.0000 | 25 |
GO:0055082 | cellular chemical homeostasis | 33/300 | 812/18670 | 0.0000 | 0.0000 | 33 |
GO:0043086 | negative regulation of catalytic activity | 33/300 | 815/18670 | 0.0000 | 0.0000 | 33 |
GO:0002573 | myeloid leukocyte differentiation | 15/300 | 204/18670 | 0.0000 | 0.0000 | 15 |
GO:0006979 | response to oxidative stress | 23/300 | 451/18670 | 0.0000 | 0.0001 | 23 |
GO:0098771 | inorganic ion homeostasis | 31/300 | 741/18670 | 0.0000 | 0.0001 | 31 |
GO:2001236 | regulation of extrinsic apoptotic signaling pathway | 13/300 | 155/18670 | 0.0000 | 0.0001 | 13 |
GO:0055076 | transition metal ion homeostasis | 12/300 | 131/18670 | 0.0000 | 0.0001 | 12 |
GO:1901215 | negative regulation of neuron death | 15/300 | 208/18670 | 0.0000 | 0.0001 | 15 |
GO:1900407 | regulation of cellular response to oxidative stress | 10/300 | 88/18670 | 0.0000 | 0.0001 | 10 |
GO:2000116 | regulation of cysteine-type endopeptidase activity | 16/300 | 239/18670 | 0.0000 | 0.0001 | 16 |
GO:0043302 | positive regulation of leukocyte degranulation | 6/300 | 24/18670 | 0.0000 | 0.0001 | 6 |
GO:0009991 | response to extracellular stimulus | 25/300 | 531/18670 | 0.0000 | 0.0001 | 25 |
GO:0006914 | autophagy | 24/300 | 496/18670 | 0.0000 | 0.0001 | 24 |
GO:0061919 | process utilizing autophagic mechanism | 24/300 | 496/18670 | 0.0000 | 0.0001 | 24 |
GO:1903708 | positive regulation of hemopoiesis | 14/300 | 185/18670 | 0.0000 | 0.0001 | 14 |
GO:0098609 | cell-cell adhesion | 33/300 | 839/18670 | 0.0000 | 0.0001 | 33 |
GO:0034599 | cellular response to oxidative stress | 18/300 | 302/18670 | 0.0000 | 0.0001 | 18 |
GO:0046651 | lymphocyte proliferation | 17/300 | 272/18670 | 0.0000 | 0.0001 | 17 |
GO:0043281 | regulation of cysteine-type endopeptidase activity involved in apoptotic process | 15/300 | 215/18670 | 0.0000 | 0.0001 | 15 |
GO:0002699 | positive regulation of immune effector process | 15/300 | 216/18670 | 0.0000 | 0.0001 | 15 |
GO:0071407 | cellular response to organic cyclic compound | 25/300 | 542/18670 | 0.0000 | 0.0001 | 25 |
GO:0045785 | positive regulation of cell adhesion | 21/300 | 403/18670 | 0.0000 | 0.0001 | 21 |
GO:1903039 | positive regulation of leukocyte cell-cell adhesion | 15/300 | 218/18670 | 0.0000 | 0.0001 | 15 |
GO:0031400 | negative regulation of protein modification process | 27/300 | 618/18670 | 0.0000 | 0.0001 | 27 |
GO:0009895 | negative regulation of catabolic process | 18/300 | 308/18670 | 0.0000 | 0.0001 | 18 |
GO:2001242 | regulation of intrinsic apoptotic signaling pathway | 13/300 | 165/18670 | 0.0000 | 0.0001 | 13 |
GO:0050801 | ion homeostasis | 32/300 | 811/18670 | 0.0000 | 0.0001 | 32 |
GO:0009617 | response to bacterium | 29/300 | 699/18670 | 0.0000 | 0.0001 | 29 |
GO:0070663 | regulation of leukocyte proliferation | 15/300 | 222/18670 | 0.0000 | 0.0001 | 15 |
GO:0030316 | osteoclast differentiation | 10/300 | 97/18670 | 0.0000 | 0.0001 | 10 |
GO:1902882 | regulation of response to oxidative stress | 10/300 | 97/18670 | 0.0000 | 0.0001 | 10 |
GO:0097191 | extrinsic apoptotic signaling pathway | 15/300 | 224/18670 | 0.0000 | 0.0001 | 15 |
GO:0002685 | regulation of leukocyte migration | 14/300 | 196/18670 | 0.0000 | 0.0001 | 14 |
GO:1902175 | regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | 6/300 | 27/18670 | 0.0000 | 0.0001 | 6 |
GO:1902107 | positive regulation of leukocyte differentiation | 12/300 | 144/18670 | 0.0000 | 0.0001 | 12 |
GO:0045089 | positive regulation of innate immune response | 20/300 | 381/18670 | 0.0000 | 0.0001 | 20 |
GO:1901652 | response to peptide | 24/300 | 520/18670 | 0.0000 | 0.0001 | 24 |
GO:0002440 | production of molecular mediator of immune response | 17/300 | 286/18670 | 0.0000 | 0.0001 | 17 |
GO:0051051 | negative regulation of transport | 24/300 | 522/18670 | 0.0000 | 0.0001 | 24 |
GO:0010564 | regulation of cell cycle process | 31/300 | 789/18670 | 0.0000 | 0.0001 | 31 |
GO:0045088 | regulation of innate immune response | 22/300 | 452/18670 | 0.0000 | 0.0001 | 22 |
GO:0043549 | regulation of kinase activity | 33/300 | 870/18670 | 0.0000 | 0.0001 | 33 |
GO:0045859 | regulation of protein kinase activity | 31/300 | 792/18670 | 0.0000 | 0.0001 | 31 |
GO:0002764 | immune response-regulating signaling pathway | 28/300 | 675/18670 | 0.0000 | 0.0001 | 28 |
GO:0042089 | cytokine biosynthetic process | 11/300 | 123/18670 | 0.0000 | 0.0002 | 11 |
GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress | 7/300 | 43/18670 | 0.0000 | 0.0002 | 7 |
GO:0043062 | extracellular structure organization | 21/300 | 422/18670 | 0.0000 | 0.0002 | 21 |
GO:0009611 | response to wounding | 28/300 | 678/18670 | 0.0000 | 0.0002 | 28 |
GO:0042107 | cytokine metabolic process | 11/300 | 124/18670 | 0.0000 | 0.0002 | 11 |
GO:0051101 | regulation of DNA binding | 11/300 | 124/18670 | 0.0000 | 0.0002 | 11 |
GO:0040008 | regulation of growth | 28/300 | 679/18670 | 0.0000 | 0.0002 | 28 |
GO:0002697 | regulation of immune effector process | 22/300 | 458/18670 | 0.0000 | 0.0002 | 22 |
GO:0052548 | regulation of endopeptidase activity | 21/300 | 425/18670 | 0.0000 | 0.0002 | 21 |
GO:0031330 | negative regulation of cellular catabolic process | 16/300 | 264/18670 | 0.0000 | 0.0002 | 16 |
GO:0010506 | regulation of autophagy | 18/300 | 327/18670 | 0.0000 | 0.0002 | 18 |
GO:0042110 | T cell activation | 22/300 | 464/18670 | 0.0000 | 0.0002 | 22 |
GO:2001235 | positive regulation of apoptotic signaling pathway | 13/300 | 179/18670 | 0.0000 | 0.0002 | 13 |
GO:0071887 | leukocyte apoptotic process | 10/300 | 104/18670 | 0.0000 | 0.0002 | 10 |
GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 10/300 | 104/18670 | 0.0000 | 0.0002 | 10 |
GO:0050878 | regulation of body fluid levels | 23/300 | 501/18670 | 0.0000 | 0.0002 | 23 |
GO:0034394 | protein localization to cell surface | 8/300 | 63/18670 | 0.0000 | 0.0002 | 8 |
GO:0051090 | regulation of DNA-binding transcription factor activity | 21/300 | 432/18670 | 0.0000 | 0.0002 | 21 |
GO:0055065 | metal ion homeostasis | 27/300 | 653/18670 | 0.0000 | 0.0002 | 27 |
GO:0051046 | regulation of secretion | 31/300 | 811/18670 | 0.0000 | 0.0002 | 31 |
GO:0032944 | regulation of mononuclear cell proliferation | 14/300 | 209/18670 | 0.0000 | 0.0002 | 14 |
GO:0006875 | cellular metal ion homeostasis | 25/300 | 579/18670 | 0.0000 | 0.0002 | 25 |
GO:0033002 | muscle cell proliferation | 15/300 | 239/18670 | 0.0000 | 0.0002 | 15 |
GO:0006974 | cellular response to DNA damage stimulus | 32/300 | 854/18670 | 0.0000 | 0.0002 | 32 |
GO:0043300 | regulation of leukocyte degranulation | 7/300 | 46/18670 | 0.0000 | 0.0002 | 7 |
GO:0006826 | iron ion transport | 8/300 | 64/18670 | 0.0000 | 0.0002 | 8 |
GO:0051251 | positive regulation of lymphocyte activation | 18/300 | 334/18670 | 0.0000 | 0.0002 | 18 |
GO:0043434 | response to peptide hormone | 21/300 | 436/18670 | 0.0000 | 0.0002 | 21 |
GO:0031347 | regulation of defense response | 33/300 | 901/18670 | 0.0000 | 0.0002 | 33 |
GO:1903037 | regulation of leukocyte cell-cell adhesion | 17/300 | 304/18670 | 0.0000 | 0.0002 | 17 |
GO:0036293 | response to decreased oxygen levels | 19/300 | 370/18670 | 0.0000 | 0.0002 | 19 |
GO:0006897 | endocytosis | 31/300 | 820/18670 | 0.0000 | 0.0002 | 31 |
GO:0032930 | positive regulation of superoxide anion generation | 5/300 | 19/18670 | 0.0000 | 0.0003 | 5 |
GO:0045921 | positive regulation of exocytosis | 9/300 | 88/18670 | 0.0000 | 0.0003 | 9 |
GO:0016049 | cell growth | 22/300 | 484/18670 | 0.0000 | 0.0003 | 22 |
GO:0060759 | regulation of response to cytokine stimulus | 13/300 | 190/18670 | 0.0000 | 0.0003 | 13 |
GO:1903530 | regulation of secretion by cell | 29/300 | 753/18670 | 0.0000 | 0.0003 | 29 |
GO:0052547 | regulation of peptidase activity | 21/300 | 452/18670 | 0.0000 | 0.0004 | 21 |
GO:0031098 | stress-activated protein kinase signaling cascade | 17/300 | 315/18670 | 0.0000 | 0.0004 | 17 |
GO:0072593 | reactive oxygen species metabolic process | 16/300 | 284/18670 | 0.0000 | 0.0004 | 16 |
GO:0051348 | negative regulation of transferase activity | 16/300 | 285/18670 | 0.0000 | 0.0004 | 16 |
GO:0022409 | positive regulation of cell-cell adhesion | 15/300 | 255/18670 | 0.0000 | 0.0004 | 15 |
GO:0002218 | activation of innate immune response | 17/300 | 319/18670 | 0.0000 | 0.0004 | 17 |
GO:0030098 | lymphocyte differentiation | 18/300 | 353/18670 | 0.0000 | 0.0004 | 18 |
GO:0002701 | negative regulation of production of molecular mediator of immune response | 6/300 | 35/18670 | 0.0000 | 0.0004 | 6 |
GO:0031589 | cell-substrate adhesion | 18/300 | 354/18670 | 0.0000 | 0.0004 | 18 |
GO:0036473 | cell death in response to oxidative stress | 9/300 | 93/18670 | 0.0000 | 0.0004 | 9 |
GO:0033673 | negative regulation of kinase activity | 15/300 | 257/18670 | 0.0000 | 0.0004 | 15 |
GO:0048660 | regulation of smooth muscle cell proliferation | 12/300 | 169/18670 | 0.0000 | 0.0004 | 12 |
GO:0051100 | negative regulation of binding | 12/300 | 169/18670 | 0.0000 | 0.0004 | 12 |
GO:0002761 | regulation of myeloid leukocyte differentiation | 10/300 | 117/18670 | 0.0000 | 0.0005 | 10 |
GO:0019852 | L-ascorbic acid metabolic process | 4/300 | 11/18670 | 0.0000 | 0.0005 | 4 |
GO:0045628 | regulation of T-helper 2 cell differentiation | 4/300 | 11/18670 | 0.0000 | 0.0005 | 4 |
GO:0009894 | regulation of catabolic process | 34/300 | 979/18670 | 0.0000 | 0.0005 | 34 |
GO:0031667 | response to nutrient levels | 22/300 | 499/18670 | 0.0000 | 0.0005 | 22 |
GO:1903307 | positive regulation of regulated secretory pathway | 7/300 | 53/18670 | 0.0000 | 0.0005 | 7 |
GO:0010742 | macrophage derived foam cell differentiation | 6/300 | 36/18670 | 0.0000 | 0.0005 | 6 |
GO:0033572 | transferrin transport | 6/300 | 36/18670 | 0.0000 | 0.0005 | 6 |
GO:0090077 | foam cell differentiation | 6/300 | 36/18670 | 0.0000 | 0.0005 | 6 |
GO:0090322 | regulation of superoxide metabolic process | 6/300 | 36/18670 | 0.0000 | 0.0005 | 6 |
GO:0097242 | amyloid-beta clearance | 6/300 | 36/18670 | 0.0000 | 0.0005 | 6 |
GO:0051047 | positive regulation of secretion | 20/300 | 428/18670 | 0.0000 | 0.0005 | 20 |
GO:0048659 | smooth muscle cell proliferation | 12/300 | 171/18670 | 0.0000 | 0.0005 | 12 |
GO:0032928 | regulation of superoxide anion generation | 5/300 | 22/18670 | 0.0000 | 0.0005 | 5 |
GO:0071404 | cellular response to low-density lipoprotein particle stimulus | 5/300 | 22/18670 | 0.0000 | 0.0005 | 5 |
GO:0002312 | B cell activation involved in immune response | 8/300 | 73/18670 | 0.0000 | 0.0005 | 8 |
GO:0002702 | positive regulation of production of molecular mediator of immune response | 9/300 | 95/18670 | 0.0000 | 0.0005 | 9 |
GO:0042100 | B cell proliferation | 9/300 | 95/18670 | 0.0000 | 0.0005 | 9 |
GO:0002822 | regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 11/300 | 145/18670 | 0.0000 | 0.0005 | 11 |
GO:0070848 | response to growth factor | 28/300 | 736/18670 | 0.0000 | 0.0005 | 28 |
GO:0002703 | regulation of leukocyte mediated immunity | 13/300 | 201/18670 | 0.0000 | 0.0005 | 13 |
GO:0050870 | positive regulation of T cell activation | 13/300 | 202/18670 | 0.0000 | 0.0005 | 13 |
GO:1903201 | regulation of oxidative stress-induced cell death | 8/300 | 75/18670 | 0.0000 | 0.0006 | 8 |
GO:0051272 | positive regulation of cellular component movement | 24/300 | 585/18670 | 0.0000 | 0.0006 | 24 |
GO:0002758 | innate immune response-activating signal transduction | 16/300 | 298/18670 | 0.0000 | 0.0006 | 16 |
GO:0045936 | negative regulation of phosphate metabolic process | 24/300 | 586/18670 | 0.0000 | 0.0006 | 24 |
GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway | 9/300 | 98/18670 | 0.0000 | 0.0006 | 9 |
GO:0006469 | negative regulation of protein kinase activity | 14/300 | 235/18670 | 0.0000 | 0.0006 | 14 |
GO:0071888 | macrophage apoptotic process | 4/300 | 12/18670 | 0.0000 | 0.0006 | 4 |
GO:0010563 | negative regulation of phosphorus metabolic process | 24/300 | 587/18670 | 0.0000 | 0.0006 | 24 |
GO:0015682 | ferric iron transport | 6/300 | 38/18670 | 0.0000 | 0.0006 | 6 |
GO:0072512 | trivalent inorganic cation transport | 6/300 | 38/18670 | 0.0000 | 0.0006 | 6 |
GO:0022407 | regulation of cell-cell adhesion | 19/300 | 403/18670 | 0.0000 | 0.0006 | 19 |
GO:0030198 | extracellular matrix organization | 18/300 | 368/18670 | 0.0000 | 0.0006 | 18 |
GO:0043122 | regulation of I-kappaB kinase/NF-kappaB signaling | 14/300 | 237/18670 | 0.0000 | 0.0006 | 14 |
GO:0009117 | nucleotide metabolic process | 27/300 | 709/18670 | 0.0000 | 0.0006 | 27 |
GO:0007249 | I-kappaB kinase/NF-kappaB signaling | 15/300 | 269/18670 | 0.0000 | 0.0006 | 15 |
GO:0050670 | regulation of lymphocyte proliferation | 13/300 | 208/18670 | 0.0000 | 0.0007 | 13 |
GO:0051402 | neuron apoptotic process | 14/300 | 239/18670 | 0.0000 | 0.0007 | 14 |
GO:0043534 | blood vessel endothelial cell migration | 12/300 | 180/18670 | 0.0000 | 0.0007 | 12 |
GO:0048661 | positive regulation of smooth muscle cell proliferation | 9/300 | 101/18670 | 0.0000 | 0.0007 | 9 |
GO:1902105 | regulation of leukocyte differentiation | 15/300 | 272/18670 | 0.0000 | 0.0007 | 15 |
GO:0043523 | regulation of neuron apoptotic process | 13/300 | 210/18670 | 0.0000 | 0.0007 | 13 |
GO:0006753 | nucleoside phosphate metabolic process | 27/300 | 716/18670 | 0.0000 | 0.0007 | 27 |
GO:0031663 | lipopolysaccharide-mediated signaling pathway | 7/300 | 58/18670 | 0.0000 | 0.0007 | 7 |
GO:0019216 | regulation of lipid metabolic process | 19/300 | 410/18670 | 0.0000 | 0.0007 | 19 |
GO:0031349 | positive regulation of defense response | 22/300 | 521/18670 | 0.0000 | 0.0007 | 22 |
GO:0043536 | positive regulation of blood vessel endothelial cell migration | 8/300 | 79/18670 | 0.0000 | 0.0007 | 8 |
GO:0007599 | hemostasis | 17/300 | 341/18670 | 0.0000 | 0.0008 | 17 |
GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 27/300 | 719/18670 | 0.0000 | 0.0008 | 27 |
GO:0002719 | negative regulation of cytokine production involved in immune response | 5/300 | 25/18670 | 0.0000 | 0.0008 | 5 |
GO:1903827 | regulation of cellular protein localization | 22/300 | 524/18670 | 0.0000 | 0.0008 | 22 |
GO:0002757 | immune response-activating signal transduction | 25/300 | 641/18670 | 0.0000 | 0.0008 | 25 |
GO:0009636 | response to toxic substance | 22/300 | 525/18670 | 0.0000 | 0.0008 | 22 |
GO:0042113 | B cell activation | 16/300 | 310/18670 | 0.0000 | 0.0008 | 16 |
GO:0048872 | homeostasis of number of cells | 14/300 | 246/18670 | 0.0000 | 0.0009 | 14 |
GO:0043408 | regulation of MAPK cascade | 28/300 | 768/18670 | 0.0000 | 0.0009 | 28 |
GO:1905475 | regulation of protein localization to membrane | 12/300 | 187/18670 | 0.0001 | 0.0009 | 12 |
GO:0050863 | regulation of T cell activation | 16/300 | 314/18670 | 0.0001 | 0.0009 | 16 |
GO:0002286 | T cell activation involved in immune response | 9/300 | 106/18670 | 0.0001 | 0.0010 | 9 |
GO:0006879 | cellular iron ion homeostasis | 7/300 | 61/18670 | 0.0001 | 0.0010 | 7 |
GO:1901653 | cellular response to peptide | 18/300 | 385/18670 | 0.0001 | 0.0010 | 18 |
GO:0048145 | regulation of fibroblast proliferation | 8/300 | 83/18670 | 0.0001 | 0.0010 | 8 |
GO:0002819 | regulation of adaptive immune response | 11/300 | 160/18670 | 0.0001 | 0.0010 | 11 |
GO:0002523 | leukocyte migration involved in inflammatory response | 4/300 | 14/18670 | 0.0001 | 0.0010 | 4 |
GO:0045064 | T-helper 2 cell differentiation | 4/300 | 14/18670 | 0.0001 | 0.0010 | 4 |
GO:0098657 | import into cell | 32/300 | 945/18670 | 0.0001 | 0.0010 | 32 |
GO:0002705 | positive regulation of leukocyte mediated immunity | 10/300 | 133/18670 | 0.0001 | 0.0010 | 10 |
GO:0002562 | somatic diversification of immune receptors via germline recombination within a single locus | 7/300 | 62/18670 | 0.0001 | 0.0010 | 7 |
GO:0016444 | somatic cell DNA recombination | 7/300 | 62/18670 | 0.0001 | 0.0010 | 7 |
GO:0002718 | regulation of cytokine production involved in immune response | 8/300 | 84/18670 | 0.0001 | 0.0010 | 8 |
GO:0048144 | fibroblast proliferation | 8/300 | 84/18670 | 0.0001 | 0.0010 | 8 |
GO:0045597 | positive regulation of cell differentiation | 33/300 | 991/18670 | 0.0001 | 0.0010 | 33 |
GO:0000188 | inactivation of MAPK activity | 5/300 | 27/18670 | 0.0001 | 0.0011 | 5 |
GO:0060341 | regulation of cellular localization | 31/300 | 906/18670 | 0.0001 | 0.0011 | 31 |
GO:0030334 | regulation of cell migration | 32/300 | 950/18670 | 0.0001 | 0.0011 | 32 |
GO:0051403 | stress-activated MAPK cascade | 15/300 | 286/18670 | 0.0001 | 0.0011 | 15 |
GO:0046686 | response to cadmium ion | 7/300 | 63/18670 | 0.0001 | 0.0011 | 7 |
GO:0051924 | regulation of calcium ion transport | 14/300 | 254/18670 | 0.0001 | 0.0011 | 14 |
GO:0043112 | receptor metabolic process | 12/300 | 192/18670 | 0.0001 | 0.0011 | 12 |
GO:0051170 | import into nucleus | 11/300 | 163/18670 | 0.0001 | 0.0011 | 11 |
GO:1903555 | regulation of tumor necrosis factor superfamily cytokine production | 11/300 | 163/18670 | 0.0001 | 0.0011 | 11 |
GO:0071375 | cellular response to peptide hormone stimulus | 16/300 | 321/18670 | 0.0001 | 0.0011 | 16 |
GO:0070542 | response to fatty acid | 8/300 | 86/18670 | 0.0001 | 0.0012 | 8 |
GO:0030335 | positive regulation of cell migration | 22/300 | 544/18670 | 0.0001 | 0.0012 | 22 |
GO:0010959 | regulation of metal ion transport | 18/300 | 394/18670 | 0.0001 | 0.0012 | 18 |
GO:0042326 | negative regulation of phosphorylation | 20/300 | 468/18670 | 0.0001 | 0.0012 | 20 |
GO:0001666 | response to hypoxia | 17/300 | 359/18670 | 0.0001 | 0.0012 | 17 |
GO:0080135 | regulation of cellular response to stress | 27/300 | 746/18670 | 0.0001 | 0.0012 | 27 |
GO:0031623 | receptor internalization | 9/300 | 111/18670 | 0.0001 | 0.0012 | 9 |
GO:0002467 | germinal center formation | 4/300 | 15/18670 | 0.0001 | 0.0012 | 4 |
GO:2000377 | regulation of reactive oxygen species metabolic process | 12/300 | 195/18670 | 0.0001 | 0.0012 | 12 |
GO:0071363 | cellular response to growth factor stimulus | 26/300 | 706/18670 | 0.0001 | 0.0012 | 26 |
GO:0010389 | regulation of G2/M transition of mitotic cell cycle | 12/300 | 196/18670 | 0.0001 | 0.0013 | 12 |
GO:1903532 | positive regulation of secretion by cell | 18/300 | 399/18670 | 0.0001 | 0.0014 | 18 |
GO:0071706 | tumor necrosis factor superfamily cytokine production | 11/300 | 168/18670 | 0.0001 | 0.0014 | 11 |
GO:0071675 | regulation of mononuclear cell migration | 6/300 | 46/18670 | 0.0001 | 0.0014 | 6 |
GO:0032602 | chemokine production | 8/300 | 89/18670 | 0.0001 | 0.0014 | 8 |
GO:0042035 | regulation of cytokine biosynthetic process | 9/300 | 114/18670 | 0.0001 | 0.0015 | 9 |
GO:0030001 | metal ion transport | 30/300 | 883/18670 | 0.0001 | 0.0015 | 30 |
GO:0009411 | response to UV | 10/300 | 141/18670 | 0.0001 | 0.0015 | 10 |
GO:0006732 | coenzyme metabolic process | 18/300 | 403/18670 | 0.0001 | 0.0015 | 18 |
GO:0055086 | nucleobase-containing small molecule metabolic process | 28/300 | 801/18670 | 0.0001 | 0.0016 | 28 |
GO:0097067 | cellular response to thyroid hormone stimulus | 4/300 | 16/18670 | 0.0001 | 0.0016 | 4 |
GO:0044843 | cell cycle G1/S phase transition | 15/300 | 298/18670 | 0.0001 | 0.0016 | 15 |
GO:0016241 | regulation of macroautophagy | 11/300 | 171/18670 | 0.0001 | 0.0016 | 11 |
GO:0006909 | phagocytosis | 17/300 | 369/18670 | 0.0001 | 0.0016 | 17 |
GO:0010743 | regulation of macrophage derived foam cell differentiation | 5/300 | 30/18670 | 0.0001 | 0.0016 | 5 |
GO:0061082 | myeloid leukocyte cytokine production | 5/300 | 30/18670 | 0.0001 | 0.0016 | 5 |
GO:0006606 | protein import into nucleus | 10/300 | 143/18670 | 0.0001 | 0.0016 | 10 |
GO:0040017 | positive regulation of locomotion | 23/300 | 598/18670 | 0.0001 | 0.0016 | 23 |
GO:0045639 | positive regulation of myeloid cell differentiation | 8/300 | 91/18670 | 0.0001 | 0.0016 | 8 |
GO:0060333 | interferon-gamma-mediated signaling pathway | 8/300 | 91/18670 | 0.0001 | 0.0016 | 8 |
GO:0007596 | blood coagulation | 16/300 | 336/18670 | 0.0001 | 0.0017 | 16 |
GO:0002253 | activation of immune response | 26/300 | 724/18670 | 0.0001 | 0.0017 | 26 |
GO:0006935 | chemotaxis | 24/300 | 644/18670 | 0.0001 | 0.0018 | 24 |
GO:0042060 | wound healing | 22/300 | 564/18670 | 0.0001 | 0.0018 | 22 |
GO:0033273 | response to vitamin | 8/300 | 93/18670 | 0.0001 | 0.0019 | 8 |
GO:0002224 | toll-like receptor signaling pathway | 10/300 | 146/18670 | 0.0001 | 0.0019 | 10 |
GO:0042330 | taxis | 24/300 | 646/18670 | 0.0001 | 0.0019 | 24 |
GO:0090087 | regulation of peptide transport | 26/300 | 729/18670 | 0.0001 | 0.0019 | 26 |
GO:0010744 | positive regulation of macrophage derived foam cell differentiation | 4/300 | 17/18670 | 0.0001 | 0.0019 | 4 |
GO:0051897 | positive regulation of protein kinase B signaling | 11/300 | 176/18670 | 0.0001 | 0.0019 | 11 |
GO:1901699 | cellular response to nitrogen compound | 24/300 | 648/18670 | 0.0001 | 0.0020 | 24 |
GO:2000147 | positive regulation of cell motility | 22/300 | 568/18670 | 0.0001 | 0.0020 | 22 |
GO:0001959 | regulation of cytokine-mediated signaling pathway | 11/300 | 177/18670 | 0.0001 | 0.0020 | 11 |
GO:0050817 | coagulation | 16/300 | 342/18670 | 0.0001 | 0.0020 | 16 |
GO:0043542 | endothelial cell migration | 14/300 | 273/18670 | 0.0001 | 0.0020 | 14 |
GO:0051099 | positive regulation of binding | 11/300 | 179/18670 | 0.0002 | 0.0022 | 11 |
GO:0002712 | regulation of B cell mediated immunity | 6/300 | 51/18670 | 0.0002 | 0.0023 | 6 |
GO:0002889 | regulation of immunoglobulin mediated immune response | 6/300 | 51/18670 | 0.0002 | 0.0023 | 6 |
GO:0051169 | nuclear transport | 16/300 | 346/18670 | 0.0002 | 0.0023 | 16 |
GO:0071346 | cellular response to interferon-gamma | 11/300 | 180/18670 | 0.0002 | 0.0023 | 11 |
GO:0071466 | cellular response to xenobiotic stimulus | 11/300 | 180/18670 | 0.0002 | 0.0023 | 11 |
GO:0051223 | regulation of protein transport | 25/300 | 699/18670 | 0.0002 | 0.0023 | 25 |
GO:0016242 | negative regulation of macroautophagy | 5/300 | 33/18670 | 0.0002 | 0.0023 | 5 |
GO:0033028 | myeloid cell apoptotic process | 5/300 | 33/18670 | 0.0002 | 0.0023 | 5 |
GO:0045191 | regulation of isotype switching | 5/300 | 33/18670 | 0.0002 | 0.0023 | 5 |
GO:0031329 | regulation of cellular catabolic process | 29/300 | 871/18670 | 0.0002 | 0.0024 | 29 |
GO:0048545 | response to steroid hormone | 17/300 | 385/18670 | 0.0002 | 0.0024 | 17 |
GO:0016447 | somatic recombination of immunoglobulin gene segments | 6/300 | 52/18670 | 0.0002 | 0.0024 | 6 |
GO:1902749 | regulation of cell cycle G2/M phase transition | 12/300 | 213/18670 | 0.0002 | 0.0024 | 12 |
GO:0000082 | G1/S transition of mitotic cell cycle | 14/300 | 279/18670 | 0.0002 | 0.0024 | 14 |
GO:0070201 | regulation of establishment of protein localization | 26/300 | 746/18670 | 0.0002 | 0.0026 | 26 |
GO:0010631 | epithelial cell migration | 16/300 | 351/18670 | 0.0002 | 0.0026 | 16 |
GO:0043409 | negative regulation of MAPK cascade | 11/300 | 184/18670 | 0.0002 | 0.0027 | 11 |
GO:0045851 | pH reduction | 6/300 | 53/18670 | 0.0002 | 0.0027 | 6 |
GO:1905517 | macrophage migration | 6/300 | 53/18670 | 0.0002 | 0.0027 | 6 |
GO:0002200 | somatic diversification of immune receptors | 7/300 | 75/18670 | 0.0002 | 0.0027 | 7 |
GO:0150076 | neuroinflammatory response | 7/300 | 75/18670 | 0.0002 | 0.0027 | 7 |
GO:1902176 | negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | 4/300 | 19/18670 | 0.0002 | 0.0028 | 4 |
GO:0090132 | epithelium migration | 16/300 | 354/18670 | 0.0002 | 0.0028 | 16 |
GO:0071241 | cellular response to inorganic substance | 12/300 | 217/18670 | 0.0002 | 0.0028 | 12 |
GO:0001933 | negative regulation of protein phosphorylation | 18/300 | 429/18670 | 0.0002 | 0.0028 | 18 |
GO:0043535 | regulation of blood vessel endothelial cell migration | 10/300 | 156/18670 | 0.0002 | 0.0029 | 10 |
GO:0002763 | positive regulation of myeloid leukocyte differentiation | 6/300 | 54/18670 | 0.0002 | 0.0029 | 6 |
GO:0043392 | negative regulation of DNA binding | 6/300 | 54/18670 | 0.0002 | 0.0029 | 6 |
GO:0002687 | positive regulation of leukocyte migration | 9/300 | 128/18670 | 0.0002 | 0.0029 | 9 |
GO:0010595 | positive regulation of endothelial cell migration | 9/300 | 128/18670 | 0.0002 | 0.0029 | 9 |
GO:0002367 | cytokine production involved in immune response | 8/300 | 102/18670 | 0.0002 | 0.0031 | 8 |
GO:0048589 | developmental growth | 24/300 | 674/18670 | 0.0002 | 0.0031 | 24 |
GO:0042306 | regulation of protein import into nucleus | 6/300 | 55/18670 | 0.0002 | 0.0031 | 6 |
GO:0040013 | negative regulation of locomotion | 17/300 | 396/18670 | 0.0002 | 0.0031 | 17 |
GO:0090130 | tissue migration | 16/300 | 360/18670 | 0.0003 | 0.0032 | 16 |
GO:1903829 | positive regulation of cellular protein localization | 15/300 | 324/18670 | 0.0003 | 0.0032 | 15 |
GO:0007229 | integrin-mediated signaling pathway | 8/300 | 103/18670 | 0.0003 | 0.0033 | 8 |
GO:0043407 | negative regulation of MAP kinase activity | 7/300 | 78/18670 | 0.0003 | 0.0033 | 7 |
GO:0033194 | response to hydroperoxide | 4/300 | 20/18670 | 0.0003 | 0.0033 | 4 |
GO:0071636 | positive regulation of transforming growth factor beta production | 4/300 | 20/18670 | 0.0003 | 0.0033 | 4 |
GO:0006882 | cellular zinc ion homeostasis | 5/300 | 36/18670 | 0.0003 | 0.0033 | 5 |
GO:0042554 | superoxide anion generation | 5/300 | 36/18670 | 0.0003 | 0.0033 | 5 |
GO:0071248 | cellular response to metal ion | 11/300 | 190/18670 | 0.0003 | 0.0033 | 11 |
GO:0032680 | regulation of tumor necrosis factor production | 10/300 | 160/18670 | 0.0003 | 0.0033 | 10 |
GO:0030183 | B cell differentiation | 9/300 | 131/18670 | 0.0003 | 0.0033 | 9 |
GO:0032946 | positive regulation of mononuclear cell proliferation | 9/300 | 131/18670 | 0.0003 | 0.0033 | 9 |
GO:0098754 | detoxification | 9/300 | 131/18670 | 0.0003 | 0.0033 | 9 |
GO:1903078 | positive regulation of protein localization to plasma membrane | 6/300 | 56/18670 | 0.0003 | 0.0033 | 6 |
GO:1903202 | negative regulation of oxidative stress-induced cell death | 6/300 | 56/18670 | 0.0003 | 0.0033 | 6 |
GO:0046822 | regulation of nucleocytoplasmic transport | 8/300 | 104/18670 | 0.0003 | 0.0034 | 8 |
GO:0017144 | drug metabolic process | 28/300 | 851/18670 | 0.0003 | 0.0034 | 28 |
GO:0055072 | iron ion homeostasis | 7/300 | 79/18670 | 0.0003 | 0.0034 | 7 |
GO:0005996 | monosaccharide metabolic process | 14/300 | 292/18670 | 0.0003 | 0.0035 | 14 |
GO:0009410 | response to xenobiotic stimulus | 14/300 | 292/18670 | 0.0003 | 0.0035 | 14 |
GO:0043280 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | 9/300 | 132/18670 | 0.0003 | 0.0035 | 9 |
GO:0030212 | hyaluronan metabolic process | 5/300 | 37/18670 | 0.0003 | 0.0036 | 5 |
GO:1900408 | negative regulation of cellular response to oxidative stress | 6/300 | 57/18670 | 0.0003 | 0.0036 | 6 |
GO:0022617 | extracellular matrix disassembly | 7/300 | 80/18670 | 0.0003 | 0.0036 | 7 |
GO:0019882 | antigen processing and presentation | 12/300 | 226/18670 | 0.0003 | 0.0037 | 12 |
GO:0051235 | maintenance of location | 15/300 | 330/18670 | 0.0003 | 0.0037 | 15 |
GO:0032640 | tumor necrosis factor production | 10/300 | 163/18670 | 0.0003 | 0.0037 | 10 |
GO:0016236 | macroautophagy | 14/300 | 295/18670 | 0.0003 | 0.0038 | 14 |
GO:0032355 | response to estradiol | 9/300 | 134/18670 | 0.0003 | 0.0038 | 9 |
GO:0070838 | divalent metal ion transport | 19/300 | 483/18670 | 0.0003 | 0.0038 | 19 |
GO:0034109 | homotypic cell-cell adhesion | 7/300 | 81/18670 | 0.0003 | 0.0038 | 7 |
GO:1902041 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | 6/300 | 58/18670 | 0.0003 | 0.0039 | 6 |
GO:1904589 | regulation of protein import | 6/300 | 58/18670 | 0.0003 | 0.0039 | 6 |
GO:0035690 | cellular response to drug | 16/300 | 369/18670 | 0.0003 | 0.0039 | 16 |
GO:0001909 | leukocyte mediated cytotoxicity | 8/300 | 107/18670 | 0.0003 | 0.0039 | 8 |
GO:0048524 | positive regulation of viral process | 8/300 | 107/18670 | 0.0003 | 0.0039 | 8 |
GO:0055069 | zinc ion homeostasis | 5/300 | 38/18670 | 0.0003 | 0.0039 | 5 |
GO:0050727 | regulation of inflammatory response | 19/300 | 485/18670 | 0.0003 | 0.0040 | 19 |
GO:0051347 | positive regulation of transferase activity | 23/300 | 649/18670 | 0.0004 | 0.0041 | 23 |
GO:0090068 | positive regulation of cell cycle process | 14/300 | 298/18670 | 0.0004 | 0.0041 | 14 |
GO:1902883 | negative regulation of response to oxidative stress | 6/300 | 59/18670 | 0.0004 | 0.0042 | 6 |
GO:0006790 | sulfur compound metabolic process | 16/300 | 372/18670 | 0.0004 | 0.0042 | 16 |
GO:0006164 | purine nucleotide biosynthetic process | 14/300 | 300/18670 | 0.0004 | 0.0043 | 14 |
GO:0045582 | positive regulation of T cell differentiation | 7/300 | 83/18670 | 0.0004 | 0.0043 | 7 |
GO:0072511 | divalent inorganic cation transport | 19/300 | 489/18670 | 0.0004 | 0.0043 | 19 |
GO:0006925 | inflammatory cell apoptotic process | 4/300 | 22/18670 | 0.0004 | 0.0043 | 4 |
GO:1905521 | regulation of macrophage migration | 5/300 | 39/18670 | 0.0004 | 0.0043 | 5 |
GO:0032101 | regulation of response to external stimulus | 29/300 | 913/18670 | 0.0004 | 0.0043 | 29 |
GO:0034341 | response to interferon-gamma | 11/300 | 199/18670 | 0.0004 | 0.0044 | 11 |
GO:0045930 | negative regulation of mitotic cell cycle | 15/300 | 338/18670 | 0.0004 | 0.0045 | 15 |
GO:0060627 | regulation of vesicle-mediated transport | 20/300 | 532/18670 | 0.0004 | 0.0046 | 20 |
GO:0070665 | positive regulation of leukocyte proliferation | 9/300 | 139/18670 | 0.0004 | 0.0047 | 9 |
GO:0006163 | purine nucleotide metabolic process | 21/300 | 575/18670 | 0.0004 | 0.0048 | 21 |
GO:0001558 | regulation of cell growth | 17/300 | 416/18670 | 0.0004 | 0.0048 | 17 |
GO:0043491 | protein kinase B signaling | 13/300 | 269/18670 | 0.0004 | 0.0048 | 13 |
GO:0043433 | negative regulation of DNA-binding transcription factor activity | 10/300 | 170/18670 | 0.0004 | 0.0048 | 10 |
GO:0009396 | folic acid-containing compound biosynthetic process | 3/300 | 10/18670 | 0.0005 | 0.0050 | 3 |
GO:0140052 | cellular response to oxidised low-density lipoprotein particle stimulus | 3/300 | 10/18670 | 0.0005 | 0.0050 | 3 |
GO:0000041 | transition metal ion transport | 8/300 | 112/18670 | 0.0005 | 0.0050 | 8 |
GO:1990748 | cellular detoxification | 8/300 | 112/18670 | 0.0005 | 0.0050 | 8 |
GO:0000715 | nucleotide-excision repair, DNA damage recognition | 4/300 | 23/18670 | 0.0005 | 0.0050 | 4 |
GO:0010634 | positive regulation of epithelial cell migration | 10/300 | 171/18670 | 0.0005 | 0.0050 | 10 |
GO:0030278 | regulation of ossification | 11/300 | 203/18670 | 0.0005 | 0.0050 | 11 |
GO:0006913 | nucleocytoplasmic transport | 15/300 | 343/18670 | 0.0005 | 0.0051 | 15 |
GO:0008286 | insulin receptor signaling pathway | 9/300 | 141/18670 | 0.0005 | 0.0051 | 9 |
GO:0032623 | interleukin-2 production | 6/300 | 62/18670 | 0.0005 | 0.0051 | 6 |
GO:0046620 | regulation of organ growth | 8/300 | 113/18670 | 0.0005 | 0.0052 | 8 |
GO:0032868 | response to insulin | 13/300 | 272/18670 | 0.0005 | 0.0052 | 13 |
GO:0046637 | regulation of alpha-beta T cell differentiation | 6/300 | 63/18670 | 0.0005 | 0.0055 | 6 |
GO:1904377 | positive regulation of protein localization to cell periphery | 6/300 | 63/18670 | 0.0005 | 0.0055 | 6 |
GO:0030217 | T cell differentiation | 12/300 | 240/18670 | 0.0005 | 0.0057 | 12 |
GO:0071417 | cellular response to organonitrogen compound | 21/300 | 585/18670 | 0.0005 | 0.0057 | 21 |
GO:0071677 | positive regulation of mononuclear cell migration | 4/300 | 24/18670 | 0.0005 | 0.0057 | 4 |
GO:0002639 | positive regulation of immunoglobulin production | 5/300 | 42/18670 | 0.0005 | 0.0058 | 5 |
GO:0009165 | nucleotide biosynthetic process | 16/300 | 386/18670 | 0.0005 | 0.0058 | 16 |
GO:0016445 | somatic diversification of immunoglobulins | 6/300 | 64/18670 | 0.0006 | 0.0059 | 6 |
GO:0045670 | regulation of osteoclast differentiation | 6/300 | 64/18670 | 0.0006 | 0.0059 | 6 |
GO:0050792 | regulation of viral process | 11/300 | 208/18670 | 0.0006 | 0.0059 | 11 |
GO:0061061 | muscle structure development | 23/300 | 672/18670 | 0.0006 | 0.0060 | 23 |
GO:0072522 | purine-containing compound biosynthetic process | 14/300 | 313/18670 | 0.0006 | 0.0060 | 14 |
GO:1900180 | regulation of protein localization to nucleus | 8/300 | 116/18670 | 0.0006 | 0.0060 | 8 |
GO:0051346 | negative regulation of hydrolase activity | 18/300 | 466/18670 | 0.0006 | 0.0060 | 18 |
GO:0008285 | negative regulation of cell proliferation | 25/300 | 760/18670 | 0.0006 | 0.0061 | 25 |
GO:0051701 | interaction with host | 11/300 | 209/18670 | 0.0006 | 0.0061 | 11 |
GO:0045787 | positive regulation of cell cycle | 16/300 | 389/18670 | 0.0006 | 0.0061 | 16 |
GO:1901293 | nucleoside phosphate biosynthetic process | 16/300 | 390/18670 | 0.0006 | 0.0063 | 16 |
GO:0097529 | myeloid leukocyte migration | 11/300 | 210/18670 | 0.0006 | 0.0063 | 11 |
GO:0051896 | regulation of protein kinase B signaling | 12/300 | 244/18670 | 0.0006 | 0.0063 | 12 |
GO:0006898 | receptor-mediated endocytosis | 14/300 | 316/18670 | 0.0006 | 0.0064 | 14 |
GO:0043524 | negative regulation of neuron apoptotic process | 9/300 | 147/18670 | 0.0006 | 0.0064 | 9 |
GO:0045672 | positive regulation of osteoclast differentiation | 4/300 | 25/18670 | 0.0006 | 0.0064 | 4 |
GO:0051156 | glucose 6-phosphate metabolic process | 4/300 | 25/18670 | 0.0006 | 0.0064 | 4 |
GO:2000679 | positive regulation of transcription regulatory region DNA binding | 4/300 | 25/18670 | 0.0006 | 0.0064 | 4 |
GO:0072507 | divalent inorganic cation homeostasis | 19/300 | 513/18670 | 0.0007 | 0.0069 | 19 |
GO:0000086 | G2/M transition of mitotic cell cycle | 12/300 | 247/18670 | 0.0007 | 0.0069 | 12 |
GO:0097237 | cellular response to toxic substance | 12/300 | 247/18670 | 0.0007 | 0.0069 | 12 |
GO:0002706 | regulation of lymphocyte mediated immunity | 9/300 | 149/18670 | 0.0007 | 0.0070 | 9 |
GO:2001056 | positive regulation of cysteine-type endopeptidase activity | 9/300 | 149/18670 | 0.0007 | 0.0070 | 9 |
GO:0006816 | calcium ion transport | 17/300 | 434/18670 | 0.0007 | 0.0070 | 17 |
GO:2000117 | negative regulation of cysteine-type endopeptidase activity | 7/300 | 92/18670 | 0.0007 | 0.0071 | 7 |
GO:0016051 | carbohydrate biosynthetic process | 11/300 | 214/18670 | 0.0007 | 0.0072 | 11 |
GO:0097066 | response to thyroid hormone | 4/300 | 26/18670 | 0.0007 | 0.0074 | 4 |
GO:0001503 | ossification | 16/300 | 398/18670 | 0.0008 | 0.0075 | 16 |
GO:0010951 | negative regulation of endopeptidase activity | 12/300 | 250/18670 | 0.0008 | 0.0076 | 12 |
GO:0032869 | cellular response to insulin stimulus | 11/300 | 216/18670 | 0.0008 | 0.0077 | 11 |
GO:0002460 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 15/300 | 361/18670 | 0.0008 | 0.0078 | 15 |
GO:0045621 | positive regulation of lymphocyte differentiation | 7/300 | 94/18670 | 0.0008 | 0.0079 | 7 |
GO:0017157 | regulation of exocytosis | 11/300 | 217/18670 | 0.0008 | 0.0079 | 11 |
GO:0043393 | regulation of protein binding | 11/300 | 217/18670 | 0.0008 | 0.0079 | 11 |
GO:0050864 | regulation of B cell activation | 10/300 | 184/18670 | 0.0008 | 0.0079 | 10 |
GO:0042308 | negative regulation of protein import into nucleus | 3/300 | 12/18670 | 0.0008 | 0.0079 | 3 |
GO:1904590 | negative regulation of protein import | 3/300 | 12/18670 | 0.0008 | 0.0079 | 3 |
GO:0045861 | negative regulation of proteolysis | 15/300 | 363/18670 | 0.0008 | 0.0081 | 15 |
GO:0030168 | platelet activation | 9/300 | 153/18670 | 0.0008 | 0.0082 | 9 |
GO:0070227 | lymphocyte apoptotic process | 6/300 | 69/18670 | 0.0008 | 0.0082 | 6 |
GO:0051928 | positive regulation of calcium ion transport | 8/300 | 123/18670 | 0.0008 | 0.0082 | 8 |
GO:0071621 | granulocyte chemotaxis | 8/300 | 123/18670 | 0.0008 | 0.0082 | 8 |
GO:0007162 | negative regulation of cell adhesion | 13/300 | 289/18670 | 0.0008 | 0.0082 | 13 |
GO:0042116 | macrophage activation | 7/300 | 95/18670 | 0.0009 | 0.0082 | 7 |
GO:1903076 | regulation of protein localization to plasma membrane | 7/300 | 95/18670 | 0.0009 | 0.0082 | 7 |
GO:0032673 | regulation of interleukin-4 production | 4/300 | 27/18670 | 0.0009 | 0.0082 | 4 |
GO:0002204 | somatic recombination of immunoglobulin genes involved in immune response | 5/300 | 47/18670 | 0.0009 | 0.0087 | 5 |
GO:0002208 | somatic diversification of immunoglobulins involved in immune response | 5/300 | 47/18670 | 0.0009 | 0.0087 | 5 |
GO:0043370 | regulation of CD4-positive, alpha-beta T cell differentiation | 5/300 | 47/18670 | 0.0009 | 0.0087 | 5 |
GO:0045190 | isotype switching | 5/300 | 47/18670 | 0.0009 | 0.0087 | 5 |
GO:0046638 | positive regulation of alpha-beta T cell differentiation | 5/300 | 47/18670 | 0.0009 | 0.0087 | 5 |
GO:2001239 | regulation of extrinsic apoptotic signaling pathway in absence of ligand | 5/300 | 47/18670 | 0.0009 | 0.0087 | 5 |
GO:0030162 | regulation of proteolysis | 26/300 | 831/18670 | 0.0010 | 0.0090 | 26 |
GO:0043903 | regulation of symbiosis, encompassing mutualism through parasitism | 11/300 | 222/18670 | 0.0010 | 0.0091 | 11 |
GO:0072521 | purine-containing compound metabolic process | 21/300 | 613/18670 | 0.0010 | 0.0091 | 21 |
GO:0042440 | pigment metabolic process | 6/300 | 71/18670 | 0.0010 | 0.0092 | 6 |
GO:0036296 | response to increased oxygen levels | 4/300 | 28/18670 | 0.0010 | 0.0092 | 4 |
GO:0090383 | phagosome acidification | 4/300 | 28/18670 | 0.0010 | 0.0092 | 4 |
GO:0001774 | microglial cell activation | 5/300 | 48/18670 | 0.0010 | 0.0094 | 5 |
GO:0002269 | leukocyte activation involved in inflammatory response | 5/300 | 48/18670 | 0.0010 | 0.0094 | 5 |
GO:0046364 | monosaccharide biosynthetic process | 7/300 | 98/18670 | 0.0010 | 0.0095 | 7 |
GO:0010763 | positive regulation of fibroblast migration | 3/300 | 13/18670 | 0.0010 | 0.0097 | 3 |
GO:0042178 | xenobiotic catabolic process | 3/300 | 13/18670 | 0.0010 | 0.0097 | 3 |
GO:0038034 | signal transduction in absence of ligand | 6/300 | 72/18670 | 0.0011 | 0.0097 | 6 |
GO:0097192 | extrinsic apoptotic signaling pathway in absence of ligand | 6/300 | 72/18670 | 0.0011 | 0.0097 | 6 |
GO:0007160 | cell-matrix adhesion | 11/300 | 225/18670 | 0.0011 | 0.0099 | 11 |
GO:0033157 | regulation of intracellular protein transport | 11/300 | 225/18670 | 0.0011 | 0.0099 | 11 |