Top 1000 genes under the two top-value methods

Figure 1. Top 1000 genes with the highest ATC and SD values.

Figure 1. Top 1000 genes with the highest ATC and SD values.

Compare classifications

Figure 2. Conseusus partitions from ATC:skmeans and SD:kmeans methods.

Figure 2. Conseusus partitions from ATC:skmeans and SD:kmeans methods.

Dimension reduction by UMAP

UMAP plots with 2-group classification for ATC:skmeans and 2-group classification for SD:kmeans:

Figure 3. UMAP plots for visualizing the two classifications. Classification on the left plot is from ATC:skmeans and on the right is from SD:kmeans.

Figure 3. UMAP plots for visualizing the two classifications. Classification on the left plot is from ATC:skmeans and on the right is from SD:kmeans.

Signature genes (FDR < 0.05)

Signature genes from two classifications:

ATC:skmeans (2 groups)

Figure 4A. Signature genes from ATC:skmeans (2-group classification).

Figure 4A. Signature genes from ATC:skmeans (2-group classification).

SD:kmeans (2 groups)

Figure 4B. Signature genes from SD:kmeans (2-group classification).

Figure 4B. Signature genes from SD:kmeans (2-group classification).

Overlap of the two signature lists:

Figure 5. Overlap of signatures in ATC:skmeans and SD:kmeans.

Figure 5. Overlap of signatures in ATC:skmeans and SD:kmeans.

The signature genes are put into three groups, termed as:

Figure 6. Heatmaps of ATC:skmeans specific signatures, SD:kmeans specific signatures and common signatures in the two classifcations.

Figure 6. Heatmaps of ATC:skmeans specific signatures, SD:kmeans specific signatures and common signatures in the two classifcations.

Gene Ontology enrichment

Gene Ontology enrichment to the three set of genes are performed by hypergenometric test (with the clusterProfiler package). BP ontologies (Biological Process) is only applied and the significant GO terms are filtered by FDR < 0.01. The enriched GO terms are visualized as a heatmap by their similarities between GO terms (with GOSemSim package). GO terms are split and clustered with the simplifyEnrichment package. The keywords of the summaries of GO functions in each cluster are visualized by word clouds.

The most left heatmap illustrates the FDR of GO terms for each gene list. Red basically means significant.

Figure 7. Gene ontology enrichment (FDR < 0.001) on the three sets of genes illustrated in the previous Figure.

Figure 7. Gene ontology enrichment (FDR < 0.001) on the three sets of genes illustrated in the previous Figure.

A1 (394 terms)

ID Description GeneRatio BgRatio pvalue p.adjust Count
GO:0033993 response to lipid 81/553 865/18862 0e+00 0e+00 81
GO:0014070 response to organic cyclic compound 73/553 907/18862 0e+00 0e+00 73
GO:0009725 response to hormone 71/553 876/18862 0e+00 0e+00 71
GO:0043270 positive regulation of ion transport 59/553 660/18862 0e+00 0e+00 59
GO:0003013 circulatory system process 56/553 610/18862 0e+00 0e+00 56
GO:0051050 positive regulation of transport 69/553 883/18862 0e+00 0e+00 69
GO:0009611 response to wounding 57/553 654/18862 0e+00 0e+00 57
GO:0007417 central nervous system development 72/553 980/18862 0e+00 0e+00 72
GO:0019725 cellular homeostasis 69/553 937/18862 0e+00 0e+00 69
GO:0006935 chemotaxis 54/553 643/18862 0e+00 0e+00 54
GO:0042330 taxis 54/553 645/18862 0e+00 0e+00 54
GO:0008284 positive regulation of cell population proliferation 68/553 941/18862 0e+00 0e+00 68
GO:0042391 regulation of membrane potential 42/553 431/18862 0e+00 0e+00 42
GO:0007268 chemical synaptic transmission 55/553 683/18862 0e+00 0e+00 55
GO:0098916 anterograde trans-synaptic signaling 55/553 683/18862 0e+00 0e+00 55
GO:0044070 regulation of anion transport 63/553 850/18862 0e+00 0e+00 63
GO:0008015 blood circulation 47/553 527/18862 0e+00 0e+00 47
GO:0010562 positive regulation of phosphorus metabolic process 69/553 982/18862 0e+00 0e+00 69
GO:0045937 positive regulation of phosphate metabolic process 69/553 982/18862 0e+00 0e+00 69
GO:0035239 tube morphogenesis 65/553 900/18862 0e+00 0e+00 65
GO:0099537 trans-synaptic signaling 55/553 690/18862 0e+00 0e+00 55
GO:0099536 synaptic signaling 56/553 712/18862 0e+00 0e+00 56
GO:0043066 negative regulation of apoptotic process 64/553 881/18862 0e+00 0e+00 64
GO:0006936 muscle contraction 37/553 352/18862 0e+00 0e+00 37
GO:0030855 epithelial cell differentiation 59/553 775/18862 0e+00 0e+00 59
GO:0051046 regulation of secretion 51/553 613/18862 0e+00 0e+00 51
GO:0042493 response to drug 37/553 359/18862 0e+00 0e+00 37
GO:0048732 gland development 40/553 413/18862 0e+00 0e+00 40
GO:0061564 axon development 45/553 507/18862 0e+00 0e+00 45
GO:0055082 cellular chemical homeostasis 60/553 811/18862 0e+00 0e+00 60
GO:0003012 muscle system process 42/553 453/18862 0e+00 0e+00 42
GO:0043069 negative regulation of programmed cell death 64/553 902/18862 0e+00 0e+00 64
GO:0008285 negative regulation of cell population proliferation 57/553 752/18862 0e+00 0e+00 57
GO:0002790 peptide secretion 39/553 401/18862 0e+00 0e+00 39
GO:0044057 regulation of system process 49/553 591/18862 0e+00 0e+00 49
GO:0023061 signal release 43/553 475/18862 0e+00 0e+00 43
GO:0060078 regulation of postsynaptic membrane potential 22/553 136/18862 0e+00 0e+00 22
GO:0007409 axonogenesis 42/553 460/18862 0e+00 0e+00 42
GO:0071417 cellular response to organonitrogen compound 51/553 643/18862 0e+00 0e+00 51
GO:0060322 head development 56/553 750/18862 0e+00 0e+00 56
GO:0010817 regulation of hormone levels 44/553 510/18862 0e+00 0e+00 44
GO:0048514 blood vessel morphogenesis 52/553 677/18862 0e+00 0e+00 52
GO:1901699 cellular response to nitrogen compound 53/553 698/18862 0e+00 0e+00 53
GO:1903793 positive regulation of anion transport 42/553 478/18862 0e+00 0e+00 42
GO:0001944 vasculature development 57/553 786/18862 0e+00 0e+00 57
GO:0072507 divalent inorganic cation homeostasis 43/553 499/18862 0e+00 0e+00 43
GO:0072503 cellular divalent inorganic cation homeostasis 42/553 480/18862 0e+00 0e+00 42
GO:0045785 positive regulation of cell adhesion 39/553 425/18862 0e+00 0e+00 39
GO:0046879 hormone secretion 32/553 302/18862 0e+00 0e+00 32
GO:0060548 negative regulation of cell death 66/553 992/18862 0e+00 0e+00 66
GO:0071692 protein localization to extracellular region 36/553 375/18862 0e+00 0e+00 36
GO:0001568 blood vessel development 55/553 754/18862 0e+00 0e+00 55
GO:0042327 positive regulation of phosphorylation 62/553 908/18862 0e+00 0e+00 62
GO:0001525 angiogenesis 47/553 588/18862 0e+00 0e+00 47
GO:0006875 cellular metal ion homeostasis 46/553 575/18862 0e+00 0e+00 46
GO:0007411 axon guidance 30/553 277/18862 0e+00 0e+00 30
GO:0048511 rhythmic process 31/553 294/18862 0e+00 0e+00 31
GO:0009914 hormone transport 32/553 312/18862 0e+00 0e+00 32
GO:0003018 vascular process in circulatory system 28/553 245/18862 0e+00 0e+00 28
GO:0097485 neuron projection guidance 30/553 278/18862 0e+00 0e+00 30
GO:0048545 response to steroid hormone 33/553 330/18862 0e+00 0e+00 33
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 27/553 230/18862 0e+00 0e+00 27
GO:0030072 peptide hormone secretion 28/553 247/18862 0e+00 0e+00 28
GO:1903530 regulation of secretion by cell 45/553 561/18862 0e+00 0e+00 45
GO:1901652 response to peptide 43/553 521/18862 0e+00 0e+00 43
GO:0030155 regulation of cell adhesion 53/553 732/18862 0e+00 0e+00 53
GO:0001934 positive regulation of protein phosphorylation 57/553 824/18862 0e+00 0e+00 57
GO:0043068 positive regulation of programmed cell death 46/553 590/18862 0e+00 0e+00 46
GO:0055074 calcium ion homeostasis 39/553 454/18862 0e+00 0e+00 39
GO:0043065 positive regulation of apoptotic process 45/553 574/18862 0e+00 0e+00 45
GO:0120039 plasma membrane bounded cell projection morphogenesis 49/553 659/18862 0e+00 0e+00 49
GO:0071396 cellular response to lipid 44/553 556/18862 0e+00 0e+00 44
GO:0048667 cell morphogenesis involved in neuron differentiation 45/553 579/18862 0e+00 0e+00 45
GO:0048858 cell projection morphogenesis 49/553 663/18862 0e+00 0e+00 49
GO:0022409 positive regulation of cell-cell adhesion 29/553 276/18862 0e+00 0e+00 29
GO:0046883 regulation of hormone secretion 28/553 260/18862 0e+00 0e+00 28
GO:0040007 growth 60/553 908/18862 0e+00 0e+00 60
GO:0006874 cellular calcium ion homeostasis 38/553 442/18862 0e+00 0e+00 38
GO:0007420 brain development 51/553 709/18862 0e+00 0e+00 51
GO:0048812 neuron projection morphogenesis 48/553 645/18862 0e+00 0e+00 48
GO:0006954 inflammatory response 54/553 775/18862 0e+00 0e+00 54
GO:0009306 protein secretion 34/553 367/18862 0e+00 0e+00 34
GO:0035592 establishment of protein localization to extracellular region 34/553 368/18862 0e+00 0e+00 34
GO:0055065 metal ion homeostasis 48/553 647/18862 0e+00 0e+00 48
GO:0045597 positive regulation of cell differentiation 57/553 845/18862 0e+00 0e+00 57
GO:0043410 positive regulation of MAPK cascade 42/553 525/18862 0e+00 0e+00 42
GO:0050673 epithelial cell proliferation 37/553 428/18862 0e+00 0e+00 37
GO:0010942 positive regulation of cell death 48/553 652/18862 0e+00 0e+00 48
GO:0030003 cellular cation homeostasis 48/553 655/18862 0e+00 0e+00 48
GO:0050678 regulation of epithelial cell proliferation 34/553 374/18862 0e+00 0e+00 34
GO:0032990 cell part morphogenesis 49/553 679/18862 0e+00 0e+00 49
GO:0000904 cell morphogenesis involved in differentiation 51/553 723/18862 0e+00 0e+00 51
GO:0098609 cell-cell adhesion 58/553 880/18862 0e+00 0e+00 58
GO:0022407 regulation of cell-cell adhesion 37/553 437/18862 0e+00 0e+00 37
GO:0090087 regulation of peptide transport 44/553 580/18862 0e+00 0e+00 44
GO:0002791 regulation of peptide secretion 30/553 308/18862 0e+00 0e+00 30
GO:0007610 behavior 42/553 541/18862 0e+00 0e+00 42
GO:0099565 chemical synaptic transmission, postsynaptic 17/553 105/18862 0e+00 0e+00 17
GO:0006873 cellular ion homeostasis 48/553 668/18862 0e+00 0e+00 48
GO:0006937 regulation of muscle contraction 21/553 161/18862 0e+00 0e+00 21
GO:0050878 regulation of body fluid levels 40/553 503/18862 0e+00 0e+00 40
GO:0090276 regulation of peptide hormone secretion 24/553 209/18862 0e+00 0e+00 24
GO:0048598 embryonic morphogenesis 43/553 569/18862 0e+00 0e+00 43
GO:0031667 response to nutrient levels 37/553 451/18862 0e+00 0e+00 37
GO:0090066 regulation of anatomical structure size 39/553 493/18862 0e+00 0e+00 39
GO:0055080 cation homeostasis 50/553 730/18862 0e+00 0e+00 50
GO:0097190 apoptotic signaling pathway 43/553 580/18862 0e+00 0e+00 43
GO:0045471 response to ethanol 18/553 126/18862 0e+00 0e+00 18
GO:0070268 cornification 17/553 113/18862 0e+00 0e+00 17
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 50/553 737/18862 0e+00 0e+00 50
GO:0060079 excitatory postsynaptic potential 16/553 100/18862 0e+00 0e+00 16
GO:1903522 regulation of blood circulation 28/553 290/18862 0e+00 0e+00 28
GO:0098771 inorganic ion homeostasis 50/553 740/18862 0e+00 0e+00 50
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 19/553 143/18862 0e+00 0e+00 19
GO:0070482 response to oxygen levels 33/553 385/18862 0e+00 0e+00 33
GO:0007159 leukocyte cell-cell adhesion 32/553 366/18862 0e+00 0e+00 32
GO:0050804 modulation of chemical synaptic transmission 34/553 405/18862 0e+00 0e+00 34
GO:0032989 cellular component morphogenesis 51/553 766/18862 0e+00 0e+00 51
GO:0099177 regulation of trans-synaptic signaling 34/553 406/18862 0e+00 0e+00 34
GO:0045766 positive regulation of angiogenesis 21/553 175/18862 0e+00 0e+00 21
GO:1904018 positive regulation of vasculature development 21/553 175/18862 0e+00 0e+00 21
GO:0050900 leukocyte migration 39/553 509/18862 0e+00 0e+00 39
GO:0032526 response to retinoic acid 16/553 103/18862 0e+00 0e+00 16
GO:0090257 regulation of muscle system process 25/553 243/18862 0e+00 0e+00 25
GO:1901653 cellular response to peptide 33/553 391/18862 0e+00 0e+00 33
GO:0043408 regulation of MAPK cascade 48/553 708/18862 0e+00 0e+00 48
GO:0007548 sex differentiation 26/553 262/18862 0e+00 0e+00 26
GO:0042060 wound healing 40/553 535/18862 0e+00 0e+00 40
GO:0033674 positive regulation of kinase activity 43/553 601/18862 0e+00 0e+00 43
GO:0009991 response to extracellular stimulus 37/553 477/18862 0e+00 0e+00 37
GO:0048589 developmental growth 43/553 605/18862 0e+00 0e+00 43
GO:0051272 positive regulation of cellular component movement 42/553 585/18862 0e+00 0e+00 42
GO:0040017 positive regulation of locomotion 42/553 586/18862 0e+00 0e+00 42
GO:0050801 ion homeostasis 51/553 787/18862 0e+00 0e+00 51
GO:0031175 neuron projection development 59/553 977/18862 0e+00 0e+00 59
GO:0008544 epidermis development 36/553 463/18862 0e+00 0e+00 36
GO:2001236 regulation of extrinsic apoptotic signaling pathway 19/553 154/18862 0e+00 0e+00 19
GO:0048608 reproductive structure development 33/553 405/18862 0e+00 0e+00 33
GO:2000147 positive regulation of cell motility 41/553 573/18862 0e+00 0e+00 41
GO:2001233 regulation of apoptotic signaling pathway 30/553 348/18862 0e+00 0e+00 30
GO:0061458 reproductive system development 33/553 408/18862 0e+00 0e+00 33
GO:0045776 negative regulation of blood pressure 10/553 40/18862 0e+00 0e+00 10
GO:0003180 aortic valve morphogenesis 9/553 31/18862 0e+00 0e+00 9
GO:0007507 heart development 40/553 555/18862 0e+00 0e+00 40
GO:0007423 sensory organ development 39/553 534/18862 0e+00 0e+00 39
GO:0051047 positive regulation of secretion 27/553 295/18862 0e+00 0e+00 27
GO:0009790 embryo development 59/553 992/18862 0e+00 0e+00 59
GO:0032880 regulation of protein localization 54/553 875/18862 0e+00 0e+00 54
GO:0006941 striated muscle contraction 20/553 176/18862 0e+00 0e+00 20
GO:0051098 regulation of binding 30/553 357/18862 0e+00 0e+00 30
GO:0048534 hematopoietic or lymphoid organ development 56/553 932/18862 0e+00 0e+00 56
GO:0071300 cellular response to retinoic acid 12/553 64/18862 0e+00 0e+00 12
GO:0042593 glucose homeostasis 23/553 229/18862 0e+00 0e+00 23
GO:0036293 response to decreased oxygen levels 30/553 360/18862 0e+00 0e+00 30
GO:0048729 tissue morphogenesis 43/553 634/18862 0e+00 0e+00 43
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 15/553 103/18862 0e+00 0e+00 15
GO:0033500 carbohydrate homeostasis 23/553 230/18862 0e+00 0e+00 23
GO:0030879 mammary gland development 17/553 132/18862 0e+00 0e+00 17
GO:0007568 aging 27/553 304/18862 0e+00 0e+00 27
GO:0045860 positive regulation of protein kinase activity 38/553 528/18862 0e+00 0e+00 38
GO:0051480 regulation of cytosolic calcium ion concentration 29/553 344/18862 0e+00 0e+00 29
GO:0006942 regulation of striated muscle contraction 14/553 91/18862 0e+00 0e+00 14
GO:0032496 response to lipopolysaccharide 28/553 326/18862 0e+00 0e+00 28
GO:0002237 response to molecule of bacterial origin 29/553 346/18862 0e+00 0e+00 29
GO:1903039 positive regulation of leukocyte cell-cell adhesion 23/553 234/18862 0e+00 0e+00 23
GO:1903532 positive regulation of secretion by cell 25/553 271/18862 0e+00 0e+00 25
GO:0001666 response to hypoxia 29/553 348/18862 0e+00 0e+00 29
GO:0048880 sensory system development 30/553 369/18862 0e+00 0e+00 30
GO:0031960 response to corticosteroid 18/553 152/18862 0e+00 0e+00 18
GO:1903037 regulation of leukocyte cell-cell adhesion 28/553 330/18862 0e+00 0e+00 28
GO:0009612 response to mechanical stimulus 21/553 202/18862 0e+00 0e+00 21
GO:0015837 amine transport 14/553 94/18862 0e+00 0e+00 14
GO:0050679 positive regulation of epithelial cell proliferation 21/553 203/18862 0e+00 0e+00 21
GO:0003176 aortic valve development 9/553 36/18862 0e+00 0e+00 9
GO:0045765 regulation of angiogenesis 28/553 335/18862 0e+00 0e+00 28
GO:0001656 metanephros development 13/553 82/18862 0e+00 0e+00 13
GO:0000165 MAPK cascade 54/553 913/18862 0e+00 0e+00 54
GO:0032355 response to estradiol 16/553 125/18862 0e+00 0e+00 16
GO:2001234 negative regulation of apoptotic signaling pathway 22/553 224/18862 0e+00 0e+00 22
GO:0061138 morphogenesis of a branching epithelium 19/553 173/18862 0e+00 0e+00 19
GO:0030073 insulin secretion 21/553 207/18862 0e+00 0e+00 21
GO:0002520 immune system development 57/553 989/18862 0e+00 0e+00 57
GO:0030097 hemopoiesis 53/553 892/18862 0e+00 0e+00 53
GO:0001654 eye development 29/553 359/18862 0e+00 0e+00 29
GO:0030335 positive regulation of cell migration 38/553 549/18862 0e+00 0e+00 38
GO:0051223 regulation of protein transport 38/553 549/18862 0e+00 0e+00 38
GO:0035296 regulation of tube diameter 16/553 127/18862 0e+00 0e+00 16
GO:0097746 blood vessel diameter maintenance 16/553 127/18862 0e+00 0e+00 16
GO:0048771 tissue remodeling 19/553 175/18862 0e+00 0e+00 19
GO:1901342 regulation of vasculature development 28/553 341/18862 0e+00 0e+00 28
GO:0051090 regulation of DNA-binding transcription factor activity 33/553 444/18862 0e+00 0e+00 33
GO:0035150 regulation of tube size 16/553 128/18862 0e+00 0e+00 16
GO:0032870 cellular response to hormone stimulus 41/553 619/18862 0e+00 0e+00 41
GO:0150063 visual system development 29/553 363/18862 0e+00 0e+00 29
GO:0008217 regulation of blood pressure 19/553 177/18862 0e+00 0e+00 19
GO:0040008 regulation of growth 42/553 644/18862 0e+00 0e+00 42
GO:0007589 body fluid secretion 13/553 86/18862 0e+00 0e+00 13
GO:0051952 regulation of amine transport 13/553 86/18862 0e+00 0e+00 13
GO:0046683 response to organophosphorus 16/553 130/18862 0e+00 0e+00 16
GO:0032635 interleukin-6 production 18/553 162/18862 0e+00 0e+00 18
GO:0019932 second-messenger-mediated signaling 26/553 307/18862 0e+00 0e+00 26
GO:0071407 cellular response to organic cyclic compound 38/553 558/18862 0e+00 0e+00 38
GO:0043010 camera-type eye development 26/553 310/18862 0e+00 0e+00 26
GO:0071214 cellular response to abiotic stimulus 27/553 330/18862 0e+00 0e+00 27
GO:0104004 cellular response to environmental stimulus 27/553 330/18862 0e+00 0e+00 27
GO:0030334 regulation of cell migration 55/553 962/18862 0e+00 0e+00 55
GO:0097191 extrinsic apoptotic signaling pathway 21/553 217/18862 0e+00 0e+00 21
GO:0034762 regulation of transmembrane transport 38/553 565/18862 0e+00 0e+00 38
GO:0051347 positive regulation of transferase activity 43/553 679/18862 0e+00 0e+00 43
GO:0043434 response to peptide hormone 32/553 435/18862 0e+00 0e+00 32
GO:0043588 skin development 31/553 415/18862 0e+00 1e-04 31
GO:0035249 synaptic transmission, glutamatergic 13/553 90/18862 0e+00 1e-04 13
GO:0051384 response to glucocorticoid 16/553 135/18862 0e+00 1e-04 16
GO:0060048 cardiac muscle contraction 16/553 135/18862 0e+00 1e-04 16
GO:1905314 semi-lunar valve development 9/553 41/18862 0e+00 1e-04 9
GO:0042129 regulation of T cell proliferation 18/553 168/18862 0e+00 1e-04 18
GO:0050670 regulation of lymphocyte proliferation 21/553 221/18862 0e+00 1e-04 21
GO:0001763 morphogenesis of a branching structure 19/553 186/18862 0e+00 1e-04 19
GO:0044706 multi-multicellular organism process 20/553 204/18862 0e+00 1e-04 20
GO:0050708 regulation of protein secretion 24/553 279/18862 0e+00 1e-04 24
GO:0032944 regulation of mononuclear cell proliferation 21/553 223/18862 0e+00 1e-04 21
GO:0070201 regulation of establishment of protein localization 38/553 574/18862 0e+00 1e-04 38
GO:0030001 metal ion transport 34/553 486/18862 0e+00 1e-04 34
GO:0051093 negative regulation of developmental process 53/553 929/18862 0e+00 1e-04 53
GO:0035270 endocrine system development 15/553 122/18862 0e+00 1e-04 15
GO:0009913 epidermal cell differentiation 28/553 360/18862 0e+00 1e-04 28
GO:0061448 connective tissue development 22/553 243/18862 0e+00 1e-04 22
GO:0051591 response to cAMP 13/553 93/18862 0e+00 1e-04 13
GO:0002064 epithelial cell development 20/553 207/18862 0e+00 1e-04 20
GO:0042476 odontogenesis 15/553 123/18862 0e+00 1e-04 15
GO:0032409 regulation of transporter activity 24/553 283/18862 0e+00 1e-04 24
GO:0008016 regulation of heart contraction 22/553 245/18862 0e+00 1e-04 22
GO:0006836 neurotransmitter transport 20/553 209/18862 0e+00 1e-04 20
GO:0051954 positive regulation of amine transport 8/553 33/18862 0e+00 1e-04 8
GO:0031099 regeneration 19/553 192/18862 0e+00 1e-04 19
GO:0034330 cell junction organization 43/553 699/18862 0e+00 1e-04 43
GO:0050727 regulation of inflammatory response 28/553 366/18862 0e+00 1e-04 28
GO:0006816 calcium ion transport 30/553 409/18862 0e+00 1e-04 30
GO:0060485 mesenchyme development 24/553 287/18862 0e+00 1e-04 24
GO:0022898 regulation of transmembrane transporter activity 23/553 268/18862 0e+00 1e-04 23
GO:0071363 cellular response to growth factor stimulus 43/553 703/18862 0e+00 1e-04 43
GO:0048754 branching morphogenesis of an epithelial tube 16/553 143/18862 0e+00 1e-04 16
GO:0001816 cytokine production 48/553 823/18862 0e+00 1e-04 48
GO:1901385 regulation of voltage-gated calcium channel activity 8/553 34/18862 0e+00 1e-04 8
GO:0051966 regulation of synaptic transmission, glutamatergic 11/553 69/18862 0e+00 1e-04 11
GO:0050728 negative regulation of inflammatory response 17/553 160/18862 0e+00 1e-04 17
GO:0003015 heart process 24/553 289/18862 0e+00 1e-04 24
GO:0014074 response to purine-containing compound 16/553 144/18862 0e+00 1e-04 16
GO:0050796 regulation of insulin secretion 18/553 178/18862 0e+00 1e-04 18
GO:0007204 positive regulation of cytosolic calcium ion concentration 25/553 310/18862 0e+00 1e-04 25
GO:0018105 peptidyl-serine phosphorylation 25/553 310/18862 0e+00 1e-04 25
GO:0097305 response to alcohol 21/553 233/18862 0e+00 1e-04 21
GO:0070848 response to growth factor 44/553 732/18862 0e+00 1e-04 44
GO:0019221 cytokine-mediated signaling pathway 47/553 804/18862 0e+00 1e-04 47
GO:0097094 craniofacial suture morphogenesis 6/553 17/18862 0e+00 1e-04 6
GO:0018209 peptidyl-serine modification 26/553 333/18862 0e+00 1e-04 26
GO:0072073 kidney epithelium development 15/553 131/18862 0e+00 1e-04 15
GO:0006939 smooth muscle contraction 13/553 100/18862 0e+00 1e-04 13
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 7/553 26/18862 0e+00 1e-04 7
GO:0007584 response to nutrient 17/553 165/18862 0e+00 1e-04 17
GO:0032755 positive regulation of interleukin-6 production 12/553 86/18862 0e+00 2e-04 12
GO:0042311 vasodilation 8/553 36/18862 0e+00 2e-04 8
GO:0051924 regulation of calcium ion transport 21/553 238/18862 0e+00 2e-04 21
GO:0070663 regulation of leukocyte proliferation 21/553 241/18862 0e+00 2e-04 21
GO:0009314 response to radiation 31/553 447/18862 0e+00 2e-04 31
GO:0051928 positive regulation of calcium ion transport 14/553 118/18862 0e+00 2e-04 14
GO:0034765 regulation of ion transmembrane transport 36/553 560/18862 0e+00 2e-04 36
GO:0030216 keratinocyte differentiation 24/553 302/18862 0e+00 2e-04 24
GO:0042063 gliogenesis 23/553 283/18862 0e+00 2e-04 23
GO:0055117 regulation of cardiac muscle contraction 11/553 75/18862 0e+00 2e-04 11
GO:0070252 actin-mediated cell contraction 14/553 120/18862 0e+00 2e-04 14
GO:0042110 T cell activation 32/553 474/18862 0e+00 2e-04 32
GO:0010035 response to inorganic substance 35/553 542/18862 0e+00 2e-04 35
GO:0045664 regulation of neuron differentiation 18/553 190/18862 0e+00 2e-04 18
GO:0010959 regulation of metal ion transport 21/553 247/18862 0e+00 3e-04 21
GO:0008361 regulation of cell size 17/553 173/18862 0e+00 3e-04 17
GO:0003006 developmental process involved in reproduction 52/553 957/18862 0e+00 3e-04 52
GO:0045989 positive regulation of striated muscle contraction 5/553 12/18862 0e+00 3e-04 5
GO:0045933 positive regulation of muscle contraction 8/553 39/18862 0e+00 3e-04 8
GO:0050832 defense response to fungus 8/553 39/18862 0e+00 3e-04 8
GO:0031669 cellular response to nutrient levels 19/553 210/18862 0e+00 3e-04 19
GO:0098660 inorganic ion transmembrane transport 48/553 860/18862 0e+00 3e-04 48
GO:0060562 epithelial tube morphogenesis 24/553 309/18862 0e+00 3e-04 24
GO:0001819 positive regulation of cytokine production 30/553 437/18862 0e+00 3e-04 30
GO:0060348 bone development 18/553 193/18862 0e+00 3e-04 18
GO:0032102 negative regulation of response to external stimulus 28/553 394/18862 0e+00 3e-04 28
GO:0007623 circadian rhythm 19/553 212/18862 0e+00 3e-04 19
GO:0050870 positive regulation of T cell activation 19/553 212/18862 0e+00 3e-04 19
GO:0048762 mesenchymal cell differentiation 20/553 231/18862 0e+00 3e-04 20
GO:0046887 positive regulation of hormone secretion 14/553 124/18862 0e+00 3e-04 14
GO:1904064 positive regulation of cation transmembrane transport 15/553 141/18862 0e+00 3e-04 15
GO:0045165 cell fate commitment 21/553 251/18862 0e+00 3e-04 21
GO:0071560 cellular response to transforming growth factor beta stimulus 21/553 251/18862 0e+00 3e-04 21
GO:0032735 positive regulation of interleukin-12 production 8/553 40/18862 0e+00 3e-04 8
GO:0046717 acid secretion 8/553 40/18862 0e+00 3e-04 8
GO:0031103 axon regeneration 9/553 52/18862 0e+00 3e-04 9
GO:0060284 regulation of cell development 32/553 485/18862 0e+00 3e-04 32
GO:0042098 T cell proliferation 18/553 195/18862 0e+00 3e-04 18
GO:0015844 monoamine transport 11/553 79/18862 0e+00 3e-04 11
GO:0007565 female pregnancy 17/553 177/18862 0e+00 3e-04 17
GO:0043393 regulation of protein binding 18/553 196/18862 0e+00 3e-04 18
GO:0007601 visual perception 19/553 215/18862 0e+00 3e-04 19
GO:0002009 morphogenesis of an epithelium 34/553 533/18862 0e+00 3e-04 34
GO:0003179 heart valve morphogenesis 9/553 53/18862 0e+00 4e-04 9
GO:0009620 response to fungus 9/553 53/18862 0e+00 4e-04 9
GO:0010332 response to gamma radiation 9/553 53/18862 0e+00 4e-04 9
GO:0009268 response to pH 8/553 41/18862 0e+00 4e-04 8
GO:0032602 chemokine production 12/553 95/18862 0e+00 4e-04 12
GO:0090277 positive regulation of peptide hormone secretion 12/553 95/18862 0e+00 4e-04 12
GO:0009617 response to bacterium 42/553 724/18862 0e+00 4e-04 42
GO:0007369 gastrulation 17/553 179/18862 0e+00 4e-04 17
GO:0050806 positive regulation of synaptic transmission 15/553 144/18862 0e+00 4e-04 15
GO:0001503 ossification 28/553 401/18862 0e+00 4e-04 28
GO:0045137 development of primary sexual characteristics 19/553 217/18862 0e+00 4e-04 19
GO:0033555 multicellular organismal response to stress 10/553 67/18862 0e+00 4e-04 10
GO:1903169 regulation of calcium ion transmembrane transport 15/553 145/18862 0e+00 4e-04 15
GO:0071559 response to transforming growth factor beta 21/553 257/18862 0e+00 4e-04 21
GO:0031670 cellular response to nutrient 8/553 42/18862 0e+00 4e-04 8
GO:0071875 adrenergic receptor signaling pathway 7/553 31/18862 0e+00 4e-04 7
GO:0048638 regulation of developmental growth 24/553 319/18862 0e+00 4e-04 24
GO:1904062 regulation of cation transmembrane transport 25/553 340/18862 0e+00 4e-04 25
GO:0032868 response to insulin 22/553 278/18862 0e+00 4e-04 22
GO:0050953 sensory perception of light stimulus 19/553 219/18862 0e+00 4e-04 19
GO:0003007 heart morphogenesis 20/553 239/18862 0e+00 4e-04 20
GO:0043549 regulation of kinase activity 49/553 905/18862 0e+00 4e-04 49
GO:0060047 heart contraction 22/553 279/18862 0e+00 4e-04 22
GO:0001817 regulation of cytokine production 44/553 781/18862 0e+00 4e-04 44
GO:0070997 neuron death 25/553 342/18862 0e+00 4e-04 25
GO:1901019 regulation of calcium ion transmembrane transporter activity 11/553 83/18862 0e+00 5e-04 11
GO:0072243 metanephric nephron epithelium development 6/553 22/18862 0e+00 5e-04 6
GO:0035637 multicellular organismal signaling 18/553 203/18862 0e+00 5e-04 18
GO:0046651 lymphocyte proliferation 22/553 282/18862 0e+00 5e-04 22
GO:0019233 sensory perception of pain 12/553 99/18862 0e+00 5e-04 12
GO:0042102 positive regulation of T cell proliferation 12/553 99/18862 0e+00 5e-04 12
GO:0071496 cellular response to external stimulus 23/553 303/18862 0e+00 5e-04 23
GO:0051216 cartilage development 17/553 185/18862 0e+00 5e-04 17
GO:0030048 actin filament-based movement 15/553 150/18862 0e+00 6e-04 15
GO:0090596 sensory organ morphogenesis 20/553 244/18862 0e+00 6e-04 20
GO:0032943 mononuclear cell proliferation 22/553 285/18862 0e+00 6e-04 22
GO:0050863 regulation of T cell activation 24/553 327/18862 0e+00 6e-04 24
GO:0045926 negative regulation of growth 20/553 245/18862 0e+00 6e-04 20
GO:0002793 positive regulation of peptide secretion 15/553 151/18862 0e+00 6e-04 15
GO:0021536 diencephalon development 10/553 71/18862 0e+00 6e-04 10
GO:0034764 positive regulation of transmembrane transport 18/553 207/18862 0e+00 6e-04 18
GO:0034767 positive regulation of ion transmembrane transport 18/553 207/18862 0e+00 6e-04 18
GO:0045859 regulation of protein kinase activity 44/553 794/18862 0e+00 6e-04 44
GO:0051051 negative regulation of transport 29/553 438/18862 0e+00 6e-04 29
GO:0051101 regulation of DNA binding 13/553 118/18862 0e+00 6e-04 13
GO:0050671 positive regulation of lymphocyte proliferation 14/553 135/18862 0e+00 6e-04 14
GO:0031102 neuron projection regeneration 9/553 58/18862 0e+00 7e-04 9
GO:0061005 cell differentiation involved in kidney development 9/553 58/18862 0e+00 7e-04 9
GO:0009266 response to temperature stimulus 19/553 228/18862 0e+00 7e-04 19
GO:0001501 skeletal system development 31/553 486/18862 0e+00 7e-04 31
GO:0045229 external encapsulating structure organization 27/553 396/18862 0e+00 7e-04 27
GO:0032946 positive regulation of mononuclear cell proliferation 14/553 136/18862 0e+00 7e-04 14
GO:0035137 hindlimb morphogenesis 7/553 34/18862 0e+00 7e-04 7
GO:0060428 lung epithelium development 7/553 34/18862 0e+00 7e-04 7
GO:1902107 positive regulation of leukocyte differentiation 15/553 154/18862 0e+00 7e-04 15
GO:1903708 positive regulation of hemopoiesis 15/553 154/18862 0e+00 7e-04 15
GO:0010720 positive regulation of cell development 22/553 290/18862 0e+00 7e-04 22
GO:0010001 glial cell differentiation 18/553 210/18862 0e+00 7e-04 18
GO:0051402 neuron apoptotic process 19/553 230/18862 1e-04 7e-04 19
GO:0098657 import into cell 19/553 230/18862 1e-04 7e-04 19
GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 9/553 59/18862 1e-04 7e-04 9
GO:0060249 anatomical structure homeostasis 30/553 466/18862 1e-04 7e-04 30
GO:0001505 regulation of neurotransmitter levels 18/553 211/18862 1e-04 7e-04 18
GO:0060037 pharyngeal system development 6/553 24/18862 1e-04 7e-04 6
GO:0048863 stem cell differentiation 20/553 251/18862 1e-04 8e-04 20
GO:0008406 gonad development 18/553 212/18862 1e-04 8e-04 18
GO:0009755 hormone-mediated signaling pathway 17/553 193/18862 1e-04 8e-04 17
GO:0032642 regulation of chemokine production 11/553 89/18862 1e-04 8e-04 11
GO:0051129 negative regulation of cellular component organization 41/553 731/18862 1e-04 8e-04 41
GO:0032615 interleukin-12 production 9/553 60/18862 1e-04 8e-04 9
GO:0032655 regulation of interleukin-12 production 9/553 60/18862 1e-04 8e-04 9
GO:0046888 negative regulation of hormone secretion 9/553 60/18862 1e-04 8e-04 9
GO:0018149 peptide cross-linking 7/553 35/18862 1e-04 8e-04 7
GO:0006959 humoral immune response 26/553 380/18862 1e-04 8e-04 26
GO:0072009 nephron epithelium development 12/553 106/18862 1e-04 9e-04 12
GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling 36/553 613/18862 1e-04 9e-04 36
GO:0032675 regulation of interleukin-6 production 15/553 158/18862 1e-04 9e-04 15
GO:0007517 muscle organ development 23/553 317/18862 1e-04 9e-04 23
GO:0003170 heart valve development 9/553 61/18862 1e-04 9e-04 9
GO:0032682 negative regulation of chemokine production 6/553 25/18862 1e-04 9e-04 6
GO:0072202 cell differentiation involved in metanephros development 6/553 25/18862 1e-04 9e-04 6
GO:0072207 metanephric epithelium development 6/553 25/18862 1e-04 9e-04 6
GO:0031668 cellular response to extracellular stimulus 19/553 235/18862 1e-04 9e-04 19
GO:0035850 epithelial cell differentiation involved in kidney development 8/553 48/18862 1e-04 9e-04 8
GO:0045596 negative regulation of cell differentiation 38/553 664/18862 1e-04 9e-04 38
GO:0060341 regulation of cellular localization 44/553 813/18862 1e-04 9e-04 44
GO:0031348 negative regulation of defense response 19/553 236/18862 1e-04 1e-03 19
GO:0032412 regulation of ion transmembrane transporter activity 20/553 257/18862 1e-04 1e-03 20
GO:0031214 biomineral tissue development 15/553 160/18862 1e-04 1e-03 15
GO:0048660 regulation of smooth muscle cell proliferation 15/553 160/18862 1e-04 1e-03 15
GO:0019730 antimicrobial humoral response 14/553 142/18862 1e-04 1e-03 14

A2 (116 terms)

ID Description GeneRatio BgRatio pvalue p.adjust Count
GO:0016071 mRNA metabolic process 52/350 882/18862 0 0e+00 52
GO:1903311 regulation of mRNA metabolic process 30/350 334/18862 0 0e+00 30
GO:0016579 protein deubiquitination 26/350 283/18862 0 0e+00 26
GO:0000375 RNA splicing, via transesterification reactions 30/350 386/18862 0 0e+00 30
GO:0044403 biological process involved in symbiotic interaction 51/350 1000/18862 0 0e+00 51
GO:0016032 viral process 49/350 942/18862 0 0e+00 49
GO:0070646 protein modification by small protein removal 26/350 300/18862 0 0e+00 26
GO:0044257 cellular protein catabolic process 44/350 797/18862 0 0e+00 44
GO:0008380 RNA splicing 33/350 481/18862 0 0e+00 33
GO:0045786 negative regulation of cell cycle 38/350 624/18862 0 0e+00 38
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 29/350 383/18862 0 0e+00 29
GO:0000398 mRNA splicing, via spliceosome 29/350 383/18862 0 0e+00 29
GO:0006397 mRNA processing 35/350 546/18862 0 0e+00 35
GO:0006119 oxidative phosphorylation 18/350 148/18862 0 0e+00 18
GO:0043620 regulation of DNA-templated transcription in response to stress 16/350 115/18862 0 0e+00 16
GO:0031329 regulation of cellular catabolic process 44/350 848/18862 0 0e+00 44
GO:0030163 protein catabolic process 47/350 948/18862 0 0e+00 47
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 13/350 77/18862 0 0e+00 13
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 15/350 109/18862 0 0e+00 15
GO:0043488 regulation of mRNA stability 19/350 188/18862 0 0e+00 19
GO:0043487 regulation of RNA stability 19/350 198/18862 0 0e+00 19
GO:0043632 modification-dependent macromolecule catabolic process 36/350 656/18862 0 0e+00 36
GO:0032446 protein modification by small protein conjugation 45/350 958/18862 0 0e+00 45
GO:0006511 ubiquitin-dependent protein catabolic process 35/350 639/18862 0 0e+00 35
GO:0051603 proteolysis involved in cellular protein catabolic process 38/350 735/18862 0 0e+00 38
GO:0060071 Wnt signaling pathway, planar cell polarity pathway 14/350 108/18862 0 0e+00 14
GO:0045333 cellular respiration 18/350 187/18862 0 0e+00 18
GO:0061013 regulation of mRNA catabolic process 19/350 210/18862 0 0e+00 19
GO:0019941 modification-dependent protein catabolic process 35/350 645/18862 0 0e+00 35
GO:0016567 protein ubiquitination 42/350 874/18862 0 0e+00 42
GO:0006521 regulation of cellular amino acid metabolic process 11/350 62/18862 0 0e+00 11
GO:0090175 regulation of establishment of planar polarity 14/350 112/18862 0 0e+00 14
GO:0022904 respiratory electron transport chain 14/350 117/18862 0 0e+00 14
GO:0001736 establishment of planar polarity 14/350 123/18862 0 0e+00 14
GO:0007164 establishment of tissue polarity 14/350 123/18862 0 0e+00 14
GO:0006913 nucleocytoplasmic transport 23/350 340/18862 0 0e+00 23
GO:1902036 regulation of hematopoietic stem cell differentiation 11/350 74/18862 0 0e+00 11
GO:0010498 proteasomal protein catabolic process 28/350 483/18862 0 0e+00 28
GO:0051169 nuclear transport 23/350 343/18862 0 0e+00 23
GO:0033238 regulation of cellular amine metabolic process 11/350 77/18862 0 0e+00 11
GO:0006091 generation of precursor metabolites and energy 29/350 524/18862 0 0e+00 29
GO:0022900 electron transport chain 16/350 178/18862 0 0e+00 16
GO:0006401 RNA catabolic process 25/350 414/18862 0 0e+00 25
GO:0015980 energy derivation by oxidation of organic compounds 20/350 278/18862 0 0e+00 20
GO:0048024 regulation of mRNA splicing, via spliceosome 12/350 100/18862 0 0e+00 12
GO:0031145 anaphase-promoting complex-dependent catabolic process 11/350 83/18862 0 0e+00 11
GO:0019884 antigen processing and presentation of exogenous antigen 16/350 185/18862 0 0e+00 16
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 25/350 425/18862 0 0e+00 25
GO:0046034 ATP metabolic process 21/350 313/18862 0 0e+00 21
GO:0001738 morphogenesis of a polarized epithelium 14/350 144/18862 0 0e+00 14
GO:0060218 hematopoietic stem cell differentiation 11/350 88/18862 0 1e-04 11
GO:0048002 antigen processing and presentation of peptide antigen 16/350 194/18862 0 1e-04 16
GO:1901532 regulation of hematopoietic progenitor cell differentiation 11/350 89/18862 0 1e-04 11
GO:0080135 regulation of cellular response to stress 33/350 699/18862 0 1e-04 33
GO:0035567 non-canonical Wnt signaling pathway 14/350 153/18862 0 1e-04 14
GO:1901361 organic cyclic compound catabolic process 31/350 637/18862 0 1e-04 31
GO:0002478 antigen processing and presentation of exogenous peptide antigen 15/350 177/18862 0 1e-04 15
GO:2000736 regulation of stem cell differentiation 12/350 112/18862 0 1e-04 12
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 11/350 93/18862 0 1e-04 11
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 10/350 75/18862 0 1e-04 10
GO:0050852 T cell receptor signaling pathway 16/350 204/18862 0 1e-04 16
GO:1902600 proton transmembrane transport 14/350 157/18862 0 1e-04 14
GO:0000209 protein polyubiquitination 21/350 337/18862 0 1e-04 21
GO:0071453 cellular response to oxygen levels 17/350 231/18862 0 1e-04 17
GO:0071456 cellular response to hypoxia 16/350 206/18862 0 1e-04 16
GO:0034655 nucleobase-containing compound catabolic process 28/350 553/18862 0 1e-04 28
GO:0046700 heterocycle catabolic process 29/350 587/18862 0 1e-04 29
GO:0019882 antigen processing and presentation 17/350 234/18862 0 1e-04 17
GO:0050684 regulation of mRNA processing 13/350 139/18862 0 1e-04 13
GO:0006402 mRNA catabolic process 22/350 375/18862 0 1e-04 22
GO:0006446 regulation of translational initiation 10/350 80/18862 0 1e-04 10
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 10/350 80/18862 0 1e-04 10
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 11/350 99/18862 0 1e-04 11
GO:0042775 mitochondrial ATP synthesis coupled electron transport 11/350 99/18862 0 1e-04 11
GO:0042773 ATP synthesis coupled electron transport 11/350 100/18862 0 1e-04 11
GO:0036294 cellular response to decreased oxygen levels 16/350 214/18862 0 1e-04 16
GO:0043484 regulation of RNA splicing 13/350 145/18862 0 2e-04 13
GO:1903793 positive regulation of anion transport 25/350 478/18862 0 2e-04 25
GO:0006520 cellular amino acid metabolic process 20/350 331/18862 0 2e-04 20
GO:0009060 aerobic respiration 10/350 86/18862 0 2e-04 10
GO:2000027 regulation of animal organ morphogenesis 14/350 176/18862 0 3e-04 14
GO:0044270 cellular nitrogen compound catabolic process 28/350 592/18862 0 3e-04 28
GO:1902750 negative regulation of cell cycle G2/M phase transition 11/350 111/18862 0 3e-04 11
GO:0071347 cellular response to interleukin-1 14/350 180/18862 0 3e-04 14
GO:0044106 cellular amine metabolic process 13/350 158/18862 0 4e-04 13
GO:0002223 stimulatory C-type lectin receptor signaling pathway 11/350 114/18862 0 4e-04 11
GO:0022613 ribonucleoprotein complex biogenesis 24/350 473/18862 0 4e-04 24
GO:0038061 NIK/NF-kappaB signaling 14/350 185/18862 0 5e-04 14
GO:0009408 response to heat 13/350 161/18862 0 5e-04 13
GO:0006635 fatty acid beta-oxidation 9/350 75/18862 0 5e-04 9
GO:0019439 aromatic compound catabolic process 28/350 609/18862 0 5e-04 28
GO:0009308 amine metabolic process 13/350 163/18862 0 5e-04 13
GO:0051170 import into nucleus 13/350 163/18862 0 5e-04 13
GO:0070482 response to oxygen levels 21/350 385/18862 0 5e-04 21
GO:0072594 establishment of protein localization to organelle 27/350 579/18862 0 5e-04 27
GO:0002429 immune response-activating cell surface receptor signaling pathway 24/350 481/18862 0 5e-04 24
GO:0002757 immune response-activating signal transduction 24/350 481/18862 0 5e-04 24
GO:0002220 innate immune response activating cell surface receptor signaling pathway 11/350 118/18862 0 5e-04 11
GO:0002758 innate immune response-activating signal transduction 11/350 119/18862 0 6e-04 11
GO:0034605 cellular response to heat 11/350 120/18862 0 6e-04 11
GO:0043687 post-translational protein modification 20/350 361/18862 0 6e-04 20
GO:0017038 protein import 14/350 194/18862 0 7e-04 14
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 10/350 100/18862 0 7e-04 10
GO:0044839 cell cycle G2/M phase transition 17/350 276/18862 0 7e-04 17
GO:0009743 response to carbohydrate 15/350 221/18862 0 7e-04 15
GO:2001020 regulation of response to DNA damage stimulus 15/350 221/18862 0 7e-04 15
GO:0034248 regulation of cellular amide metabolic process 24/350 494/18862 0 7e-04 24
GO:0044772 mitotic cell cycle phase transition 27/350 595/18862 0 7e-04 27
GO:0070498 interleukin-1-mediated signaling pathway 10/350 103/18862 0 8e-04 10
GO:0033209 tumor necrosis factor-mediated signaling pathway 13/350 174/18862 0 9e-04 13
GO:0019395 fatty acid oxidation 10/350 105/18862 0 1e-03 10
GO:0006607 NLS-bearing protein import into nucleus 5/350 20/18862 0 1e-03 5
GO:0045088 regulation of innate immune response 18/350 315/18862 0 1e-03 18
GO:0044770 cell cycle phase transition 28/350 641/18862 0 1e-03 28
GO:0002253 activation of immune response 26/350 572/18862 0 1e-03 26
GO:0000086 G2/M transition of mitotic cell cycle 16/350 258/18862 0 1e-03 16

B1 (350 terms)

ID Description GeneRatio BgRatio pvalue p.adjust Count
GO:0006259 DNA metabolic process 85/412 954/18862 0e+00 0e+00 85
GO:1903311 regulation of mRNA metabolic process 48/412 334/18862 0e+00 0e+00 48
GO:0016071 mRNA metabolic process 76/412 882/18862 0e+00 0e+00 76
GO:1903047 mitotic cell cycle process 74/412 886/18862 0e+00 0e+00 74
GO:0016032 viral process 76/412 942/18862 0e+00 0e+00 76
GO:0044772 mitotic cell cycle phase transition 60/412 595/18862 0e+00 0e+00 60
GO:0010948 negative regulation of cell cycle process 47/412 359/18862 0e+00 0e+00 47
GO:0044403 biological process involved in symbiotic interaction 77/412 1000/18862 0e+00 0e+00 77
GO:0044770 cell cycle phase transition 61/412 641/18862 0e+00 0e+00 61
GO:0006974 cellular response to DNA damage stimulus 67/412 869/18862 0e+00 0e+00 67
GO:0010564 regulation of cell cycle process 63/412 789/18862 0e+00 0e+00 63
GO:0045786 negative regulation of cell cycle 54/412 624/18862 0e+00 0e+00 54
GO:0007346 regulation of mitotic cell cycle 53/412 605/18862 0e+00 0e+00 53
GO:1901990 regulation of mitotic cell cycle phase transition 45/412 439/18862 0e+00 0e+00 45
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 42/412 383/18862 0e+00 0e+00 42
GO:0000398 mRNA splicing, via spliceosome 42/412 383/18862 0e+00 0e+00 42
GO:0006397 mRNA processing 50/412 546/18862 0e+00 0e+00 50
GO:0000375 RNA splicing, via transesterification reactions 42/412 386/18862 0e+00 0e+00 42
GO:0006281 DNA repair 51/412 569/18862 0e+00 0e+00 51
GO:1901991 negative regulation of mitotic cell cycle phase transition 34/412 250/18862 0e+00 0e+00 34
GO:0006403 RNA localization 33/412 234/18862 0e+00 0e+00 33
GO:1901987 regulation of cell cycle phase transition 46/412 478/18862 0e+00 0e+00 46
GO:0033044 regulation of chromosome organization 35/412 273/18862 0e+00 0e+00 35
GO:1901988 negative regulation of cell cycle phase transition 34/412 268/18862 0e+00 0e+00 34
GO:0008380 RNA splicing 45/412 481/18862 0e+00 0e+00 45
GO:0050684 regulation of mRNA processing 25/412 139/18862 0e+00 0e+00 25
GO:0006260 DNA replication 33/412 280/18862 0e+00 0e+00 33
GO:0060218 hematopoietic stem cell differentiation 20/412 88/18862 0e+00 0e+00 20
GO:1902749 regulation of cell cycle G2/M phase transition 29/412 219/18862 0e+00 0e+00 29
GO:0000082 G1/S transition of mitotic cell cycle 32/412 275/18862 0e+00 0e+00 32
GO:0000723 telomere maintenance 25/412 161/18862 0e+00 0e+00 25
GO:0006325 chromatin organization 56/412 807/18862 0e+00 0e+00 56
GO:2001252 positive regulation of chromosome organization 25/412 164/18862 0e+00 0e+00 25
GO:1902036 regulation of hematopoietic stem cell differentiation 18/412 74/18862 0e+00 0e+00 18
GO:0071824 protein-DNA complex subunit organization 32/412 281/18862 0e+00 0e+00 32
GO:0045930 negative regulation of mitotic cell cycle 34/412 321/18862 0e+00 0e+00 34
GO:0010389 regulation of G2/M transition of mitotic cell cycle 27/412 203/18862 0e+00 0e+00 27
GO:0032200 telomere organization 25/412 174/18862 0e+00 0e+00 25
GO:0044843 cell cycle G1/S phase transition 32/412 298/18862 0e+00 0e+00 32
GO:0002244 hematopoietic progenitor cell differentiation 24/412 161/18862 0e+00 0e+00 24
GO:0002520 immune system development 61/412 989/18862 0e+00 0e+00 61
GO:2000736 regulation of stem cell differentiation 20/412 112/18862 0e+00 0e+00 20
GO:0071103 DNA conformation change 34/412 352/18862 0e+00 0e+00 34
GO:0051052 regulation of DNA metabolic process 34/412 353/18862 0e+00 0e+00 34
GO:0048024 regulation of mRNA splicing, via spliceosome 19/412 100/18862 0e+00 0e+00 19
GO:0044839 cell cycle G2/M phase transition 30/412 276/18862 0e+00 0e+00 30
GO:0043488 regulation of mRNA stability 25/412 188/18862 0e+00 0e+00 25
GO:0032392 DNA geometric change 20/412 114/18862 0e+00 0e+00 20
GO:0065004 protein-DNA complex assembly 28/412 241/18862 0e+00 0e+00 28
GO:0070198 protein localization to chromosome, telomeric region 12/412 30/18862 0e+00 0e+00 12
GO:1901532 regulation of hematopoietic progenitor cell differentiation 18/412 89/18862 0e+00 0e+00 18
GO:0061013 regulation of mRNA catabolic process 26/412 210/18862 0e+00 0e+00 26
GO:0030097 hemopoiesis 56/412 892/18862 0e+00 0e+00 56
GO:0032204 regulation of telomere maintenance 17/412 79/18862 0e+00 0e+00 17
GO:0071897 DNA biosynthetic process 25/412 194/18862 0e+00 0e+00 25
GO:0002218 activation of innate immune response 22/412 148/18862 0e+00 0e+00 22
GO:0043487 regulation of RNA stability 25/412 198/18862 0e+00 0e+00 25
GO:0051054 positive regulation of DNA metabolic process 25/412 198/18862 0e+00 0e+00 25
GO:2000278 regulation of DNA biosynthetic process 19/412 107/18862 0e+00 0e+00 19
GO:1904356 regulation of telomere maintenance via telomere lengthening 15/412 60/18862 0e+00 0e+00 15
GO:1904851 positive regulation of establishment of protein localization to telomere 8/412 10/18862 0e+00 0e+00 8
GO:0034655 nucleobase-containing compound catabolic process 42/412 553/18862 0e+00 0e+00 42
GO:0032206 positive regulation of telomere maintenance 14/412 51/18862 0e+00 0e+00 14
GO:0000086 G2/M transition of mitotic cell cycle 28/412 258/18862 0e+00 0e+00 28
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 18/412 100/18862 0e+00 0e+00 18
GO:0048534 hematopoietic or lymphoid organ development 56/412 932/18862 0e+00 0e+00 56
GO:0043484 regulation of RNA splicing 21/412 145/18862 0e+00 0e+00 21
GO:2000573 positive regulation of DNA biosynthetic process 15/412 65/18862 0e+00 0e+00 15
GO:0070203 regulation of establishment of protein localization to telomere 8/412 11/18862 0e+00 0e+00 8
GO:1904869 regulation of protein localization to Cajal body 8/412 11/18862 0e+00 0e+00 8
GO:1904871 positive regulation of protein localization to Cajal body 8/412 11/18862 0e+00 0e+00 8
GO:1904358 positive regulation of telomere maintenance via telomere lengthening 12/412 36/18862 0e+00 0e+00 12
GO:0071826 ribonucleoprotein complex subunit organization 26/412 231/18862 0e+00 0e+00 26
GO:0034502 protein localization to chromosome 17/412 91/18862 0e+00 0e+00 17
GO:0046700 heterocycle catabolic process 42/412 587/18862 0e+00 0e+00 42
GO:0010833 telomere maintenance via telomere lengthening 16/412 80/18862 0e+00 0e+00 16
GO:0002833 positive regulation of response to biotic stimulus 27/412 258/18862 0e+00 0e+00 27
GO:0044270 cellular nitrogen compound catabolic process 42/412 592/18862 0e+00 0e+00 42
GO:0006310 DNA recombination 29/412 299/18862 0e+00 0e+00 29
GO:0070202 regulation of establishment of protein localization to chromosome 8/412 12/18862 0e+00 0e+00 8
GO:1903405 protein localization to nuclear body 8/412 12/18862 0e+00 0e+00 8
GO:1904816 positive regulation of protein localization to chromosome, telomeric region 8/412 12/18862 0e+00 0e+00 8
GO:1904867 protein localization to Cajal body 8/412 12/18862 0e+00 0e+00 8
GO:0045089 positive regulation of innate immune response 25/412 223/18862 0e+00 0e+00 25
GO:0022618 ribonucleoprotein complex assembly 25/412 224/18862 0e+00 0e+00 25
GO:0031145 anaphase-promoting complex-dependent catabolic process 16/412 83/18862 0e+00 0e+00 16
GO:1902750 negative regulation of cell cycle G2/M phase transition 18/412 111/18862 0e+00 0e+00 18
GO:0006401 RNA catabolic process 34/412 414/18862 0e+00 0e+00 34
GO:0070200 establishment of protein localization to telomere 9/412 18/18862 0e+00 0e+00 9
GO:0019439 aromatic compound catabolic process 42/412 609/18862 0e+00 0e+00 42
GO:0006521 regulation of cellular amino acid metabolic process 14/412 62/18862 0e+00 0e+00 14
GO:0006402 mRNA catabolic process 32/412 375/18862 0e+00 0e+00 32
GO:0032212 positive regulation of telomere maintenance via telomerase 11/412 33/18862 0e+00 0e+00 11
GO:0032210 regulation of telomere maintenance via telomerase 13/412 52/18862 0e+00 0e+00 13
GO:0006278 RNA-dependent DNA biosynthetic process 15/412 75/18862 0e+00 0e+00 15
GO:0051236 establishment of RNA localization 23/412 201/18862 0e+00 0e+00 23
GO:0033238 regulation of cellular amine metabolic process 15/412 77/18862 0e+00 0e+00 15
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia 15/412 77/18862 0e+00 0e+00 15
GO:0051169 nuclear transport 30/412 343/18862 0e+00 0e+00 30
GO:1904814 regulation of protein localization to chromosome, telomeric region 8/412 14/18862 0e+00 0e+00 8
GO:1990173 protein localization to nucleoplasm 8/412 14/18862 0e+00 0e+00 8
GO:0007004 telomere maintenance via telomerase 14/412 68/18862 0e+00 0e+00 14
GO:1901361 organic cyclic compound catabolic process 42/412 637/18862 0e+00 0e+00 42
GO:0006261 DNA-dependent DNA replication 20/412 157/18862 0e+00 0e+00 20
GO:0006352 DNA-templated transcription, initiation 25/412 249/18862 0e+00 0e+00 25
GO:1904874 positive regulation of telomerase RNA localization to Cajal body 8/412 15/18862 0e+00 0e+00 8
GO:0022613 ribonucleoprotein complex biogenesis 35/412 473/18862 0e+00 0e+00 35
GO:0050657 nucleic acid transport 22/412 198/18862 0e+00 0e+00 22
GO:0050658 RNA transport 22/412 198/18862 0e+00 0e+00 22
GO:0006913 nucleocytoplasmic transport 29/412 340/18862 0e+00 0e+00 29
GO:0031329 regulation of cellular catabolic process 49/412 848/18862 0e+00 0e+00 49
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 14/412 75/18862 0e+00 0e+00 14
GO:0006367 transcription initiation from RNA polymerase II promoter 21/412 187/18862 0e+00 0e+00 21
GO:0032508 DNA duplex unwinding 16/412 107/18862 0e+00 0e+00 16
GO:0048863 stem cell differentiation 24/412 251/18862 0e+00 0e+00 24
GO:0045088 regulation of innate immune response 27/412 315/18862 0e+00 0e+00 27
GO:1904872 regulation of telomerase RNA localization to Cajal body 8/412 18/18862 0e+00 0e+00 8
GO:0015931 nucleobase-containing compound transport 24/412 253/18862 0e+00 0e+00 24
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 14/412 80/18862 0e+00 0e+00 14
GO:0090670 RNA localization to Cajal body 8/412 19/18862 0e+00 0e+00 8
GO:0090671 telomerase RNA localization to Cajal body 8/412 19/18862 0e+00 0e+00 8
GO:0090672 telomerase RNA localization 8/412 19/18862 0e+00 0e+00 8
GO:0090685 RNA localization to nucleus 8/412 19/18862 0e+00 0e+00 8
GO:0060249 anatomical structure homeostasis 33/412 466/18862 0e+00 0e+00 33
GO:0070199 establishment of protein localization to chromosome 9/412 27/18862 0e+00 0e+00 9
GO:0016579 protein deubiquitination 25/412 283/18862 0e+00 0e+00 25
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 15/412 99/18862 0e+00 0e+00 15
GO:0072331 signal transduction by p53 class mediator 24/412 263/18862 0e+00 0e+00 24
GO:0000122 negative regulation of transcription by RNA polymerase II 48/412 873/18862 0e+00 0e+00 48
GO:0033260 nuclear DNA replication 12/412 59/18862 0e+00 0e+00 12
GO:0070897 transcription preinitiation complex assembly 10/412 37/18862 0e+00 0e+00 10
GO:0006302 double-strand break repair 24/412 268/18862 0e+00 0e+00 24
GO:0010638 positive regulation of organelle organization 37/412 583/18862 0e+00 0e+00 37
GO:2000045 regulation of G1/S transition of mitotic cell cycle 19/412 174/18862 0e+00 0e+00 19
GO:0044106 cellular amine metabolic process 18/412 158/18862 0e+00 0e+00 18
GO:0070646 protein modification by small protein removal 25/412 300/18862 0e+00 0e+00 25
GO:0044786 cell cycle DNA replication 12/412 64/18862 0e+00 0e+00 12
GO:0050778 positive regulation of immune response 43/412 760/18862 0e+00 0e+00 43
GO:0060071 Wnt signaling pathway, planar cell polarity pathway 15/412 108/18862 0e+00 0e+00 15
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 14/412 93/18862 0e+00 0e+00 14
GO:0002831 regulation of response to biotic stimulus 30/412 420/18862 0e+00 0e+00 30
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 15/412 109/18862 0e+00 0e+00 15
GO:0009308 amine metabolic process 18/412 163/18862 0e+00 0e+00 18
GO:0090175 regulation of establishment of planar polarity 15/412 112/18862 0e+00 0e+00 15
GO:0006303 double-strand break repair via nonhomologous end joining 14/412 98/18862 0e+00 0e+00 14
GO:0031349 positive regulation of defense response 27/412 361/18862 0e+00 0e+00 27
GO:0043620 regulation of DNA-templated transcription in response to stress 15/412 115/18862 0e+00 0e+00 15
GO:0071478 cellular response to radiation 19/412 191/18862 0e+00 0e+00 19
GO:0035567 non-canonical Wnt signaling pathway 17/412 153/18862 0e+00 0e+00 17
GO:0002220 innate immune response activating cell surface receptor signaling pathway 15/412 118/18862 0e+00 0e+00 15
GO:0002253 activation of immune response 35/412 572/18862 0e+00 0e+00 35
GO:0002758 innate immune response-activating signal transduction 15/412 119/18862 0e+00 0e+00 15
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 15/412 119/18862 0e+00 0e+00 15
GO:0070498 interleukin-1-mediated signaling pathway 14/412 103/18862 0e+00 0e+00 14
GO:0000380 alternative mRNA splicing, via spliceosome 12/412 73/18862 0e+00 0e+00 12
GO:0009314 response to radiation 30/412 447/18862 0e+00 0e+00 30
GO:0002521 leukocyte differentiation 33/412 525/18862 0e+00 0e+00 33
GO:1902806 regulation of cell cycle G1/S phase transition 19/412 195/18862 0e+00 0e+00 19
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 29/412 425/18862 0e+00 0e+00 29
GO:0006353 DNA-templated transcription, termination 12/412 75/18862 0e+00 0e+00 12
GO:0000726 non-recombinational repair 14/412 106/18862 0e+00 0e+00 14
GO:0001736 establishment of planar polarity 15/412 123/18862 0e+00 0e+00 15
GO:0007164 establishment of tissue polarity 15/412 123/18862 0e+00 0e+00 15
GO:1902807 negative regulation of cell cycle G1/S phase transition 15/412 124/18862 0e+00 0e+00 15
GO:0010212 response to ionizing radiation 16/412 142/18862 0e+00 0e+00 16
GO:0051168 nuclear export 19/412 201/18862 0e+00 0e+00 19
GO:0006289 nucleotide-excision repair 14/412 108/18862 0e+00 0e+00 14
GO:0001738 morphogenesis of a polarized epithelium 16/412 144/18862 0e+00 0e+00 16
GO:0050852 T cell receptor signaling pathway 19/412 204/18862 0e+00 0e+00 19
GO:1901998 toxin transport 9/412 39/18862 0e+00 0e+00 9
GO:0062012 regulation of small molecule metabolic process 29/412 437/18862 0e+00 0e+00 29
GO:0050686 negative regulation of mRNA processing 8/412 29/18862 0e+00 0e+00 8
GO:0010332 response to gamma radiation 10/412 53/18862 0e+00 0e+00 10
GO:0002223 stimulatory C-type lectin receptor signaling pathway 14/412 114/18862 0e+00 0e+00 14
GO:0042180 cellular ketone metabolic process 21/412 254/18862 0e+00 0e+00 21
GO:1904951 positive regulation of establishment of protein localization 24/412 328/18862 0e+00 0e+00 24
GO:0071214 cellular response to abiotic stimulus 24/412 330/18862 0e+00 0e+00 24
GO:0104004 cellular response to environmental stimulus 24/412 330/18862 0e+00 0e+00 24
GO:0010498 proteasomal protein catabolic process 30/412 483/18862 0e+00 0e+00 30
GO:0002478 antigen processing and presentation of exogenous peptide antigen 17/412 177/18862 0e+00 0e+00 17
GO:1901796 regulation of signal transduction by p53 class mediator 17/412 177/18862 0e+00 0e+00 17
GO:0070482 response to oxygen levels 26/412 385/18862 0e+00 0e+00 26
GO:0006412 translation 38/412 716/18862 0e+00 0e+00 38
GO:0070201 regulation of establishment of protein localization 33/412 574/18862 0e+00 0e+00 33
GO:1903312 negative regulation of mRNA metabolic process 12/412 88/18862 0e+00 0e+00 12
GO:0006405 RNA export from nucleus 15/412 142/18862 0e+00 0e+00 15
GO:0006091 generation of precursor metabolites and energy 31/412 524/18862 0e+00 0e+00 31
GO:0008334 histone mRNA metabolic process 7/412 24/18862 0e+00 0e+00 7
GO:0006518 peptide metabolic process 44/412 905/18862 0e+00 0e+00 44
GO:0048524 positive regulation of viral process 12/412 91/18862 0e+00 0e+00 12
GO:0071456 cellular response to hypoxia 18/412 206/18862 0e+00 0e+00 18
GO:0019884 antigen processing and presentation of exogenous antigen 17/412 185/18862 0e+00 0e+00 17
GO:0016570 histone modification 28/412 448/18862 0e+00 0e+00 28
GO:0050792 regulation of viral process 17/412 186/18862 0e+00 0e+00 17
GO:0051123 RNA polymerase II preinitiation complex assembly 7/412 25/18862 0e+00 0e+00 7
GO:0001666 response to hypoxia 24/412 348/18862 0e+00 0e+00 24
GO:0090263 positive regulation of canonical Wnt signaling pathway 15/412 147/18862 0e+00 0e+00 15
GO:0071453 cellular response to oxygen levels 19/412 231/18862 0e+00 0e+00 19
GO:0032481 positive regulation of type I interferon production 11/412 77/18862 0e+00 0e+00 11
GO:0032103 positive regulation of response to external stimulus 30/412 509/18862 0e+00 0e+00 30
GO:0016571 histone methylation 14/412 130/18862 0e+00 0e+00 14
GO:0006479 protein methylation 16/412 170/18862 0e+00 0e+00 16
GO:0008213 protein alkylation 16/412 170/18862 0e+00 0e+00 16
GO:0043043 peptide biosynthetic process 38/412 742/18862 0e+00 0e+00 38
GO:0006520 cellular amino acid metabolic process 23/412 331/18862 0e+00 0e+00 23
GO:0036294 cellular response to decreased oxygen levels 18/412 214/18862 0e+00 0e+00 18
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 10/412 64/18862 0e+00 0e+00 10
GO:0016444 somatic cell DNA recombination 10/412 64/18862 0e+00 0e+00 10
GO:0002768 immune response-regulating cell surface receptor signaling pathway 30/412 515/18862 0e+00 0e+00 30
GO:0016569 covalent chromatin modification 28/412 461/18862 0e+00 0e+00 28
GO:0051301 cell division 33/412 600/18862 0e+00 0e+00 33
GO:0000245 spliceosomal complex assembly 11/412 80/18862 0e+00 0e+00 11
GO:0048002 antigen processing and presentation of peptide antigen 17/412 194/18862 0e+00 0e+00 17
GO:0002764 immune response-regulating signaling pathway 30/412 518/18862 0e+00 0e+00 30
GO:0036293 response to decreased oxygen levels 24/412 360/18862 0e+00 0e+00 24
GO:1903827 regulation of cellular protein localization 31/412 548/18862 0e+00 0e+00 31
GO:0006323 DNA packaging 19/412 240/18862 0e+00 0e+00 19
GO:0060341 regulation of cellular localization 40/412 813/18862 0e+00 0e+00 40
GO:0032880 regulation of protein localization 42/412 875/18862 0e+00 0e+00 42
GO:0043903 regulation of biological process involved in symbiotic interaction 17/412 197/18862 0e+00 0e+00 17
GO:2000027 regulation of animal organ morphogenesis 16/412 176/18862 0e+00 0e+00 16
GO:0019042 viral latency 5/412 11/18862 0e+00 0e+00 5
GO:0006270 DNA replication initiation 8/412 40/18862 0e+00 0e+00 8
GO:0006354 DNA-templated transcription, elongation 13/412 119/18862 0e+00 0e+00 13
GO:0030177 positive regulation of Wnt signaling pathway 16/412 179/18862 0e+00 0e+00 16
GO:1903829 positive regulation of cellular protein localization 21/412 295/18862 0e+00 0e+00 21
GO:0070317 negative regulation of G0 to G1 transition 8/412 41/18862 0e+00 0e+00 8
GO:0061136 regulation of proteasomal protein catabolic process 16/412 182/18862 0e+00 1e-04 16
GO:0031056 regulation of histone modification 14/412 141/18862 0e+00 1e-04 14
GO:0002429 immune response-activating cell surface receptor signaling pathway 28/412 481/18862 0e+00 1e-04 28
GO:0002757 immune response-activating signal transduction 28/412 481/18862 0e+00 1e-04 28
GO:0050851 antigen receptor-mediated signaling pathway 22/412 323/18862 0e+00 1e-04 22
GO:0006611 protein export from nucleus 16/412 183/18862 0e+00 1e-04 16
GO:1903362 regulation of cellular protein catabolic process 19/412 251/18862 0e+00 1e-04 19
GO:0070555 response to interleukin-1 17/412 206/18862 0e+00 1e-04 17
GO:0043632 modification-dependent macromolecule catabolic process 34/412 656/18862 0e+00 1e-04 34
GO:0010565 regulation of cellular ketone metabolic process 16/412 185/18862 0e+00 1e-04 16
GO:0038061 NIK/NF-kappaB signaling 16/412 185/18862 0e+00 1e-04 16
GO:0051095 regulation of helicase activity 5/412 12/18862 0e+00 1e-04 5
GO:0000381 regulation of alternative mRNA splicing, via spliceosome 9/412 57/18862 0e+00 1e-04 9
GO:0006457 protein folding 18/412 233/18862 0e+00 1e-04 18
GO:0006283 transcription-coupled nucleotide-excision repair 10/412 73/18862 0e+00 1e-04 10
GO:0019882 antigen processing and presentation 18/412 234/18862 0e+00 1e-04 18
GO:1903131 mononuclear cell differentiation 25/412 411/18862 0e+00 1e-04 25
GO:0031503 protein-containing complex localization 20/412 283/18862 0e+00 1e-04 20
GO:2001251 negative regulation of chromosome organization 11/412 91/18862 0e+00 1e-04 11
GO:0098781 ncRNA transcription 12/412 109/18862 0e+00 1e-04 12
GO:0038095 Fc-epsilon receptor signaling pathway 15/412 169/18862 0e+00 1e-04 15
GO:0006511 ubiquitin-dependent protein catabolic process 33/412 639/18862 0e+00 1e-04 33
GO:0050821 protein stabilization 16/412 191/18862 0e+00 1e-04 16
GO:0043687 post-translational protein modification 23/412 361/18862 0e+00 1e-04 23
GO:0006418 tRNA aminoacylation for protein translation 8/412 45/18862 0e+00 1e-04 8
GO:0002200 somatic diversification of immune receptors 10/412 75/18862 0e+00 1e-04 10
GO:0030162 regulation of proteolysis 36/412 733/18862 0e+00 1e-04 36
GO:0000209 protein polyubiquitination 22/412 337/18862 0e+00 1e-04 22
GO:0038093 Fc receptor signaling pathway 18/412 239/18862 0e+00 1e-04 18
GO:0019941 modification-dependent protein catabolic process 33/412 645/18862 0e+00 1e-04 33
GO:0010499 proteasomal ubiquitin-independent protein catabolic process 6/412 22/18862 0e+00 1e-04 6
GO:0032069 regulation of nuclease activity 6/412 22/18862 0e+00 1e-04 6
GO:0044257 cellular protein catabolic process 38/412 797/18862 0e+00 1e-04 38
GO:0018205 peptidyl-lysine modification 24/412 391/18862 0e+00 1e-04 24
GO:0070316 regulation of G0 to G1 transition 8/412 46/18862 0e+00 1e-04 8
GO:0032446 protein modification by small protein conjugation 43/412 958/18862 0e+00 1e-04 43
GO:0051028 mRNA transport 14/412 152/18862 0e+00 1e-04 14
GO:0033209 tumor necrosis factor-mediated signaling pathway 15/412 174/18862 0e+00 1e-04 15
GO:0045787 positive regulation of cell cycle 24/412 395/18862 0e+00 1e-04 24
GO:0019221 cytokine-mediated signaling pathway 38/412 804/18862 0e+00 1e-04 38
GO:0045023 G0 to G1 transition 8/412 47/18862 0e+00 1e-04 8
GO:0051972 regulation of telomerase activity 8/412 47/18862 0e+00 1e-04 8
GO:1902107 positive regulation of leukocyte differentiation 14/412 154/18862 0e+00 1e-04 14
GO:1903708 positive regulation of hemopoiesis 14/412 154/18862 0e+00 1e-04 14
GO:0071482 cellular response to light stimulus 13/412 134/18862 0e+00 1e-04 13
GO:2001020 regulation of response to DNA damage stimulus 17/412 221/18862 0e+00 1e-04 17
GO:0045898 regulation of RNA polymerase II transcription preinitiation complex assembly 5/412 14/18862 0e+00 1e-04 5
GO:0043039 tRNA aminoacylation 8/412 48/18862 0e+00 1e-04 8
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 7/412 35/18862 0e+00 1e-04 7
GO:0045597 positive regulation of cell differentiation 39/412 845/18862 0e+00 1e-04 39
GO:0046649 lymphocyte activation 36/412 752/18862 0e+00 2e-04 36
GO:0090090 negative regulation of canonical Wnt signaling pathway 15/412 179/18862 0e+00 2e-04 15
GO:0043604 amide biosynthetic process 40/412 879/18862 0e+00 2e-04 40
GO:0043038 amino acid activation 8/412 49/18862 0e+00 2e-04 8
GO:0071347 cellular response to interleukin-1 15/412 180/18862 0e+00 2e-04 15
GO:0000165 MAPK cascade 41/412 913/18862 0e+00 2e-04 41
GO:0040029 regulation of gene expression, epigenetic 16/412 205/18862 0e+00 2e-04 16
GO:0009263 deoxyribonucleotide biosynthetic process 5/412 15/18862 0e+00 2e-04 5
GO:0072594 establishment of protein localization to organelle 30/412 579/18862 0e+00 2e-04 30
GO:0015980 energy derivation by oxidation of organic compounds 19/412 278/18862 0e+00 2e-04 19
GO:0006304 DNA modification 12/412 121/18862 0e+00 2e-04 12
GO:0051603 proteolysis involved in cellular protein catabolic process 35/412 735/18862 0e+00 2e-04 35
GO:1902275 regulation of chromatin organization 15/412 185/18862 0e+00 2e-04 15
GO:0030098 lymphocyte differentiation 22/412 358/18862 0e+00 2e-04 22
GO:0051170 import into nucleus 14/412 163/18862 0e+00 2e-04 14
GO:0032922 circadian regulation of gene expression 9/412 67/18862 0e+00 2e-04 9
GO:0006338 chromatin remodeling 16/412 209/18862 0e+00 2e-04 16
GO:0097193 intrinsic apoptotic signaling pathway 19/412 283/18862 0e+00 2e-04 19
GO:0033151 V(D)J recombination 5/412 16/18862 0e+00 3e-04 5
GO:1902969 mitotic DNA replication 5/412 16/18862 0e+00 3e-04 5
GO:0009060 aerobic respiration 10/412 86/18862 0e+00 3e-04 10
GO:0007059 chromosome segregation 21/412 337/18862 0e+00 3e-04 21
GO:0030099 myeloid cell differentiation 24/412 419/18862 0e+00 3e-04 24
GO:0009411 response to UV 13/412 146/18862 0e+00 3e-04 13
GO:0014070 response to organic cyclic compound 40/412 907/18862 0e+00 3e-04 40
GO:0045862 positive regulation of proteolysis 22/412 367/18862 0e+00 3e-04 22
GO:0016447 somatic recombination of immunoglobulin gene segments 8/412 54/18862 0e+00 3e-04 8
GO:0007064 mitotic sister chromatid cohesion 6/412 27/18862 0e+00 3e-04 6
GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 16/412 215/18862 0e+00 3e-04 16
GO:0006275 regulation of DNA replication 11/412 107/18862 0e+00 3e-04 11
GO:0034968 histone lysine methylation 11/412 107/18862 0e+00 3e-04 11
GO:2001022 positive regulation of response to DNA damage stimulus 11/412 107/18862 0e+00 3e-04 11
GO:0009262 deoxyribonucleotide metabolic process 7/412 40/18862 0e+00 3e-04 7
GO:0032479 regulation of type I interferon production 12/412 128/18862 0e+00 3e-04 12
GO:0031347 regulation of defense response 33/412 694/18862 0e+00 4e-04 33
GO:0032606 type I interferon production 12/412 129/18862 0e+00 4e-04 12
GO:0006368 transcription elongation from RNA polymerase II promoter 10/412 90/18862 0e+00 4e-04 10
GO:0031497 chromatin assembly 15/412 196/18862 0e+00 4e-04 15
GO:0071426 ribonucleoprotein complex export from nucleus 12/412 130/18862 0e+00 4e-04 12
GO:0031647 regulation of protein stability 19/412 295/18862 0e+00 4e-04 19
GO:0080135 regulation of cellular response to stress 33/412 699/18862 0e+00 4e-04 33
GO:0006333 chromatin assembly or disassembly 16/412 221/18862 0e+00 4e-04 16
GO:0071166 ribonucleoprotein complex localization 12/412 131/18862 0e+00 4e-04 12
GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 6/412 29/18862 0e+00 4e-04 6
GO:0000819 sister chromatid segregation 15/412 199/18862 0e+00 5e-04 15
GO:0000280 nuclear division 24/412 436/18862 0e+00 5e-04 24
GO:0034248 regulation of cellular amide metabolic process 26/412 494/18862 0e+00 5e-04 26
GO:0009124 nucleoside monophosphate biosynthetic process 7/412 43/18862 0e+00 5e-04 7
GO:2000142 regulation of DNA-templated transcription, initiation 7/412 43/18862 0e+00 5e-04 7
GO:0034504 protein localization to nucleus 18/412 275/18862 0e+00 5e-04 18
GO:0051321 meiotic cell cycle 17/412 250/18862 0e+00 5e-04 17
GO:0022900 electron transport chain 14/412 178/18862 0e+00 5e-04 14
GO:0048545 response to steroid hormone 20/412 330/18862 0e+00 6e-04 20
GO:0007339 binding of sperm to zona pellucida 7/412 44/18862 0e+00 6e-04 7
GO:0006271 DNA strand elongation involved in DNA replication 5/412 19/18862 0e+00 6e-04 5
GO:0016567 protein ubiquitination 38/412 874/18862 0e+00 6e-04 38
GO:0009725 response to hormone 38/412 876/18862 0e+00 6e-04 38
GO:0045070 positive regulation of viral genome replication 6/412 31/18862 0e+00 6e-04 6
GO:0051402 neuron apoptotic process 16/412 230/18862 0e+00 6e-04 16
GO:0030163 protein catabolic process 40/412 948/18862 1e-04 7e-04 40
GO:0048025 negative regulation of mRNA splicing, via spliceosome 5/412 20/18862 1e-04 8e-04 5
GO:0044728 DNA methylation or demethylation 10/412 99/18862 1e-04 8e-04 10
GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly 4/412 11/18862 1e-04 9e-04 4
GO:0006417 regulation of translation 23/412 425/18862 1e-04 9e-04 23
GO:0043462 regulation of ATPase activity 9/412 81/18862 1e-04 9e-04 9
GO:0030178 negative regulation of Wnt signaling pathway 15/412 212/18862 1e-04 9e-04 15
GO:0060964 regulation of gene silencing by miRNA 11/412 121/18862 1e-04 9e-04 11
GO:0051973 positive regulation of telomerase activity 6/412 33/18862 1e-04 9e-04 6
GO:0045621 positive regulation of lymphocyte differentiation 10/412 101/18862 1e-04 9e-04 10
GO:0048285 organelle fission 25/412 486/18862 1e-04 9e-04 25
GO:0016445 somatic diversification of immunoglobulins 8/412 64/18862 1e-04 9e-04 8
GO:0009165 nucleotide biosynthetic process 17/412 264/18862 1e-04 1e-03 17
GO:0060968 regulation of gene silencing 12/412 144/18862 1e-04 1e-03 12

B2 (81 terms)

ID Description GeneRatio BgRatio pvalue p.adjust Count
GO:0045055 regulated exocytosis 47/202 779/18862 0 0e+00 47
GO:0002366 leukocyte activation involved in immune response 45/202 718/18862 0 0e+00 45
GO:0002263 cell activation involved in immune response 45/202 722/18862 0 0e+00 45
GO:0002274 myeloid leukocyte activation 43/202 659/18862 0 0e+00 43
GO:0006887 exocytosis 49/202 891/18862 0 0e+00 49
GO:0043299 leukocyte degranulation 39/202 535/18862 0 0e+00 39
GO:0002444 myeloid leukocyte mediated immunity 39/202 550/18862 0 0e+00 39
GO:0002275 myeloid cell activation involved in immune response 38/202 548/18862 0 0e+00 38
GO:0002443 leukocyte mediated immunity 46/202 882/18862 0 0e+00 46
GO:0042119 neutrophil activation 35/202 500/18862 0 0e+00 35
GO:0036230 granulocyte activation 35/202 506/18862 0 0e+00 35
GO:0043312 neutrophil degranulation 33/202 485/18862 0 0e+00 33
GO:0002283 neutrophil activation involved in immune response 33/202 488/18862 0 0e+00 33
GO:0002446 neutrophil mediated immunity 33/202 499/18862 0 0e+00 33
GO:0002237 response to molecule of bacterial origin 24/202 346/18862 0 0e+00 24
GO:0009617 response to bacterium 33/202 724/18862 0 0e+00 33
GO:0033993 response to lipid 36/202 865/18862 0 0e+00 36
GO:0032496 response to lipopolysaccharide 22/202 326/18862 0 0e+00 22
GO:0006954 inflammatory response 31/202 775/18862 0 0e+00 31
GO:0030198 extracellular matrix organization 21/202 393/18862 0 0e+00 21
GO:0043062 extracellular structure organization 21/202 394/18862 0 0e+00 21
GO:0045229 external encapsulating structure organization 21/202 396/18862 0 0e+00 21
GO:0050766 positive regulation of phagocytosis 10/202 67/18862 0 0e+00 10
GO:0030155 regulation of cell adhesion 28/202 732/18862 0 0e+00 28
GO:0050764 regulation of phagocytosis 11/202 94/18862 0 0e+00 11
GO:0060627 regulation of vesicle-mediated transport 23/202 513/18862 0 0e+00 23
GO:0051050 positive regulation of transport 30/202 883/18862 0 0e+00 30
GO:0019221 cytokine-mediated signaling pathway 28/202 804/18862 0 0e+00 28
GO:0071219 cellular response to molecule of bacterial origin 14/202 209/18862 0 0e+00 14
GO:0002576 platelet degranulation 11/202 128/18862 0 0e+00 11
GO:0042110 T cell activation 20/202 474/18862 0 0e+00 20
GO:0071222 cellular response to lipopolysaccharide 13/202 197/18862 0 0e+00 13
GO:0071216 cellular response to biotic stimulus 14/202 233/18862 0 0e+00 14
GO:0045576 mast cell activation 8/202 60/18862 0 0e+00 8
GO:0043300 regulation of leukocyte degranulation 7/202 43/18862 0 0e+00 7
GO:0043303 mast cell degranulation 7/202 46/18862 0 1e-04 7
GO:0071396 cellular response to lipid 21/202 556/18862 0 1e-04 21
GO:0002279 mast cell activation involved in immune response 7/202 47/18862 0 1e-04 7
GO:0002448 mast cell mediated immunity 7/202 47/18862 0 1e-04 7
GO:0097529 myeloid leukocyte migration 13/202 218/18862 0 1e-04 13
GO:0003013 circulatory system process 22/202 610/18862 0 1e-04 22
GO:0045785 positive regulation of cell adhesion 18/202 425/18862 0 1e-04 18
GO:0030595 leukocyte chemotaxis 13/202 226/18862 0 1e-04 13
GO:0010035 response to inorganic substance 20/202 542/18862 0 1e-04 20
GO:0050900 leukocyte migration 19/202 509/18862 0 2e-04 19
GO:0060548 negative regulation of cell death 28/202 992/18862 0 2e-04 28
GO:0006959 humoral immune response 16/202 380/18862 0 3e-04 16
GO:0030162 regulation of proteolysis 23/202 733/18862 0 3e-04 23
GO:0008015 blood circulation 19/202 527/18862 0 3e-04 19
GO:0043069 negative regulation of programmed cell death 26/202 902/18862 0 3e-04 26
GO:0044089 positive regulation of cellular component biogenesis 19/202 528/18862 0 3e-04 19
GO:0030334 regulation of cell migration 27/202 962/18862 0 3e-04 27
GO:0014070 response to organic cyclic compound 26/202 907/18862 0 3e-04 26
GO:0000165 MAPK cascade 26/202 913/18862 0 4e-04 26
GO:0007568 aging 14/202 304/18862 0 4e-04 14
GO:0003073 regulation of systemic arterial blood pressure 8/202 90/18862 0 4e-04 8
GO:0060326 cell chemotaxis 14/202 306/18862 0 4e-04 14
GO:0006935 chemotaxis 21/202 643/18862 0 4e-04 21
GO:0046649 lymphocyte activation 23/202 752/18862 0 4e-04 23
GO:0042330 taxis 21/202 645/18862 0 4e-04 21
GO:1903409 reactive oxygen species biosynthetic process 9/202 123/18862 0 4e-04 9
GO:0009611 response to wounding 21/202 654/18862 0 4e-04 21
GO:0043408 regulation of MAPK cascade 22/202 708/18862 0 4e-04 22
GO:0042493 response to drug 15/202 359/18862 0 5e-04 15
GO:0019725 cellular homeostasis 26/202 937/18862 0 5e-04 26
GO:0051046 regulation of secretion 20/202 613/18862 0 6e-04 20
GO:0051345 positive regulation of hydrolase activity 23/202 776/18862 0 6e-04 23
GO:0002697 regulation of immune effector process 17/202 465/18862 0 6e-04 17
GO:0043304 regulation of mast cell degranulation 5/202 29/18862 0 7e-04 5
GO:1901652 response to peptide 18/202 521/18862 0 7e-04 18
GO:0032418 lysosome localization 7/202 74/18862 0 7e-04 7
GO:0002521 leukocyte differentiation 18/202 525/18862 0 8e-04 18
GO:0033006 regulation of mast cell activation involved in immune response 5/202 30/18862 0 8e-04 5
GO:0006909 phagocytosis 15/202 381/18862 0 8e-04 15
GO:0050865 regulation of cell activation 20/202 633/18862 0 8e-04 20
GO:0002703 regulation of leukocyte mediated immunity 11/202 209/18862 0 8e-04 11
GO:0040017 positive regulation of locomotion 19/202 586/18862 0 9e-04 19
GO:0002886 regulation of myeloid leukocyte mediated immunity 6/202 52/18862 0 9e-04 6
GO:0071417 cellular response to organonitrogen compound 20/202 643/18862 0 9e-04 20
GO:1901699 cellular response to nitrogen compound 21/202 698/18862 0 9e-04 21
GO:0022407 regulation of cell-cell adhesion 16/202 437/18862 0 9e-04 16

C1 (23 terms)

ID Description GeneRatio BgRatio pvalue p.adjust Count
GO:1903047 mitotic cell cycle process 30/139 886/18862 0 0e+00 30
GO:0044772 mitotic cell cycle phase transition 22/139 595/18862 0 0e+00 22
GO:0044770 cell cycle phase transition 22/139 641/18862 0 0e+00 22
GO:1901990 regulation of mitotic cell cycle phase transition 17/139 439/18862 0 0e+00 17
GO:0010389 regulation of G2/M transition of mitotic cell cycle 12/139 203/18862 0 0e+00 12
GO:0010564 regulation of cell cycle process 22/139 789/18862 0 0e+00 22
GO:1902749 regulation of cell cycle G2/M phase transition 12/139 219/18862 0 0e+00 12
GO:1901987 regulation of cell cycle phase transition 17/139 478/18862 0 0e+00 17
GO:0016032 viral process 24/139 942/18862 0 0e+00 24
GO:0007346 regulation of mitotic cell cycle 19/139 605/18862 0 0e+00 19
GO:0006259 DNA metabolic process 24/139 954/18862 0 0e+00 24
GO:0044403 biological process involved in symbiotic interaction 24/139 1000/18862 0 1e-04 24
GO:0006974 cellular response to DNA damage stimulus 22/139 869/18862 0 1e-04 22
GO:0000086 G2/M transition of mitotic cell cycle 12/139 258/18862 0 1e-04 12
GO:0033673 negative regulation of kinase activity 12/139 267/18862 0 1e-04 12
GO:0044839 cell cycle G2/M phase transition 12/139 276/18862 0 2e-04 12
GO:0071901 negative regulation of protein serine/threonine kinase activity 9/139 145/18862 0 2e-04 9
GO:0006469 negative regulation of protein kinase activity 11/139 243/18862 0 3e-04 11
GO:0051348 negative regulation of transferase activity 12/139 296/18862 0 3e-04 12
GO:0006281 DNA repair 16/139 569/18862 0 7e-04 16
GO:0050851 antigen receptor-mediated signaling pathway 12/139 323/18862 0 7e-04 12
GO:0002768 immune response-regulating cell surface receptor signaling pathway 15/139 515/18862 0 8e-04 15
GO:0002764 immune response-regulating signaling pathway 15/139 518/18862 0 8e-04 15

C2 (159 terms)

ID Description GeneRatio BgRatio pvalue p.adjust Count
GO:0002366 leukocyte activation involved in immune response 54/176 718/18862 0 0e+00 54
GO:0002263 cell activation involved in immune response 54/176 722/18862 0 0e+00 54
GO:0036230 granulocyte activation 47/176 506/18862 0 0e+00 47
GO:0002274 myeloid leukocyte activation 51/176 659/18862 0 0e+00 51
GO:0042119 neutrophil activation 46/176 500/18862 0 0e+00 46
GO:0043299 leukocyte degranulation 46/176 535/18862 0 0e+00 46
GO:0045055 regulated exocytosis 53/176 779/18862 0 0e+00 53
GO:0043312 neutrophil degranulation 44/176 485/18862 0 0e+00 44
GO:0002275 myeloid cell activation involved in immune response 46/176 548/18862 0 0e+00 46
GO:0002283 neutrophil activation involved in immune response 44/176 488/18862 0 0e+00 44
GO:0002444 myeloid leukocyte mediated immunity 46/176 550/18862 0 0e+00 46
GO:0002446 neutrophil mediated immunity 44/176 499/18862 0 0e+00 44
GO:0006887 exocytosis 55/176 891/18862 0 0e+00 55
GO:0002443 leukocyte mediated immunity 50/176 882/18862 0 0e+00 50
GO:0019221 cytokine-mediated signaling pathway 34/176 804/18862 0 0e+00 34
GO:0001816 cytokine production 30/176 823/18862 0 0e+00 30
GO:0002576 platelet degranulation 13/176 128/18862 0 0e+00 13
GO:0030155 regulation of cell adhesion 27/176 732/18862 0 0e+00 27
GO:0019725 cellular homeostasis 30/176 937/18862 0 0e+00 30
GO:0045785 positive regulation of cell adhesion 20/176 425/18862 0 0e+00 20
GO:0051050 positive regulation of transport 28/176 883/18862 0 0e+00 28
GO:0001817 regulation of cytokine production 26/176 781/18862 0 0e+00 26
GO:0062197 cellular response to chemical stress 17/176 347/18862 0 0e+00 17
GO:2001233 regulation of apoptotic signaling pathway 17/176 348/18862 0 0e+00 17
GO:0060548 negative regulation of cell death 29/176 992/18862 0 0e+00 29
GO:0009725 response to hormone 27/176 876/18862 0 0e+00 27
GO:0030003 cellular cation homeostasis 23/176 655/18862 0 0e+00 23
GO:0043066 negative regulation of apoptotic process 27/176 881/18862 0 0e+00 27
GO:0008284 positive regulation of cell population proliferation 28/176 941/18862 0 0e+00 28
GO:0007159 leukocyte cell-cell adhesion 17/176 366/18862 0 0e+00 17
GO:0006873 cellular ion homeostasis 23/176 668/18862 0 0e+00 23
GO:0032496 response to lipopolysaccharide 16/176 326/18862 0 0e+00 16
GO:0032870 cellular response to hormone stimulus 22/176 619/18862 0 0e+00 22
GO:0043069 negative regulation of programmed cell death 27/176 902/18862 0 0e+00 27
GO:0055080 cation homeostasis 24/176 730/18862 0 0e+00 24
GO:0050801 ion homeostasis 25/176 787/18862 0 0e+00 25
GO:0098771 inorganic ion homeostasis 24/176 740/18862 0 0e+00 24
GO:0002700 regulation of production of molecular mediator of immune response 11/176 146/18862 0 0e+00 11
GO:0055082 cellular chemical homeostasis 25/176 811/18862 0 0e+00 25
GO:0006935 chemotaxis 22/176 643/18862 0 0e+00 22
GO:0042330 taxis 22/176 645/18862 0 0e+00 22
GO:0002237 response to molecule of bacterial origin 16/176 346/18862 0 0e+00 16
GO:0098609 cell-cell adhesion 26/176 880/18862 0 0e+00 26
GO:0002285 lymphocyte activation involved in immune response 12/176 189/18862 0 0e+00 12
GO:0031589 cell-substrate adhesion 16/176 359/18862 0 0e+00 16
GO:1903039 positive regulation of leukocyte cell-cell adhesion 13/176 234/18862 0 0e+00 13
GO:0071222 cellular response to lipopolysaccharide 12/176 197/18862 0 0e+00 12
GO:0001818 negative regulation of cytokine production 16/176 367/18862 0 0e+00 16
GO:2000379 positive regulation of reactive oxygen species metabolic process 9/176 101/18862 0 0e+00 9
GO:0090322 regulation of superoxide metabolic process 6/176 32/18862 0 0e+00 6
GO:0033993 response to lipid 25/176 865/18862 0 0e+00 25
GO:0097190 apoptotic signaling pathway 20/176 580/18862 0 0e+00 20
GO:0032930 positive regulation of superoxide anion generation 5/176 18/18862 0 0e+00 5
GO:0052548 regulation of endopeptidase activity 17/176 426/18862 0 0e+00 17
GO:0071219 cellular response to molecule of bacterial origin 12/176 209/18862 0 0e+00 12
GO:0043086 negative regulation of catalytic activity 24/176 818/18862 0 0e+00 24
GO:0006914 autophagy 19/176 536/18862 0 0e+00 19
GO:0061919 process utilizing autophagic mechanism 19/176 536/18862 0 0e+00 19
GO:0034599 cellular response to oxidative stress 14/176 299/18862 0 1e-04 14
GO:0032928 regulation of superoxide anion generation 5/176 20/18862 0 1e-04 5
GO:0033572 transferrin transport 6/176 36/18862 0 1e-04 6
GO:0006954 inflammatory response 23/176 775/18862 0 1e-04 23
GO:0097191 extrinsic apoptotic signaling pathway 12/176 217/18862 0 1e-04 12
GO:0002286 T cell activation involved in immune response 9/176 111/18862 0 1e-04 9
GO:0009617 response to bacterium 22/176 724/18862 0 1e-04 22
GO:0045597 positive regulation of cell differentiation 24/176 845/18862 0 1e-04 24
GO:0014070 response to organic cyclic compound 25/176 907/18862 0 1e-04 25
GO:0033002 muscle cell proliferation 12/176 222/18862 0 1e-04 12
GO:0052547 regulation of peptidase activity 17/176 455/18862 0 1e-04 17
GO:2001234 negative regulation of apoptotic signaling pathway 12/176 224/18862 0 1e-04 12
GO:0050900 leukocyte migration 18/176 509/18862 0 1e-04 18
GO:2001236 regulation of extrinsic apoptotic signaling pathway 10/176 154/18862 0 1e-04 10
GO:0048534 hematopoietic or lymphoid organ development 25/176 932/18862 0 1e-04 25
GO:0050865 regulation of cell activation 20/176 633/18862 0 1e-04 20
GO:0071216 cellular response to biotic stimulus 12/176 233/18862 0 1e-04 12
GO:0022409 positive regulation of cell-cell adhesion 13/176 276/18862 0 1e-04 13
GO:0042110 T cell activation 17/176 474/18862 0 1e-04 17
GO:0045628 regulation of T-helper 2 cell differentiation 4/176 11/18862 0 1e-04 4
GO:0051272 positive regulation of cellular component movement 19/176 585/18862 0 1e-04 19
GO:0072593 reactive oxygen species metabolic process 13/176 281/18862 0 1e-04 13
GO:0001934 positive regulation of protein phosphorylation 23/176 824/18862 0 1e-04 23
GO:1903037 regulation of leukocyte cell-cell adhesion 14/176 330/18862 0 1e-04 14
GO:0055065 metal ion homeostasis 20/176 647/18862 0 1e-04 20
GO:0002637 regulation of immunoglobulin production 7/176 67/18862 0 1e-04 7
GO:0002440 production of molecular mediator of immune response 13/176 286/18862 0 1e-04 13
GO:0009611 response to wounding 20/176 654/18862 0 1e-04 20
GO:0010951 negative regulation of endopeptidase activity 12/176 245/18862 0 1e-04 12
GO:0030335 positive regulation of cell migration 18/176 549/18862 0 2e-04 18
GO:0043112 receptor metabolic process 10/176 168/18862 0 2e-04 10
GO:0007599 hemostasis 14/176 346/18862 0 2e-04 14
GO:0045861 negative regulation of proteolysis 14/176 346/18862 0 2e-04 14
GO:0050878 regulation of body fluid levels 17/176 503/18862 0 2e-04 17
GO:0002520 immune system development 25/176 989/18862 0 2e-04 25
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 8/176 103/18862 0 2e-04 8
GO:0010466 negative regulation of peptidase activity 12/176 257/18862 0 2e-04 12
GO:0051346 negative regulation of hydrolase activity 16/176 456/18862 0 2e-04 16
GO:0002699 positive regulation of immune effector process 11/176 219/18862 0 2e-04 11
GO:2000147 positive regulation of cell motility 18/176 573/18862 0 3e-04 18
GO:0046649 lymphocyte activation 21/176 752/18862 0 3e-04 21
GO:0006875 cellular metal ion homeostasis 18/176 575/18862 0 3e-04 18
GO:0050867 positive regulation of cell activation 15/176 412/18862 0 3e-04 15
GO:0002697 regulation of immune effector process 16/176 465/18862 0 3e-04 16
GO:0006826 iron ion transport 7/176 79/18862 0 3e-04 7
GO:0045064 T-helper 2 cell differentiation 4/176 15/18862 0 3e-04 4
GO:0031623 receptor internalization 8/176 111/18862 0 3e-04 8
GO:0030097 hemopoiesis 23/176 892/18862 0 3e-04 23
GO:0040017 positive regulation of locomotion 18/176 586/18862 0 3e-04 18
GO:0097530 granulocyte migration 9/176 148/18862 0 3e-04 9
GO:0022617 extracellular matrix disassembly 7/176 81/18862 0 3e-04 7
GO:0042060 wound healing 17/176 535/18862 0 4e-04 17
GO:0002694 regulation of leukocyte activation 18/176 594/18862 0 4e-04 18
GO:0071375 cellular response to peptide hormone stimulus 13/176 325/18862 0 4e-04 13
GO:0097067 cellular response to thyroid hormone stimulus 4/176 16/18862 0 4e-04 4
GO:0042327 positive regulation of phosphorylation 23/176 908/18862 0 4e-04 23
GO:0006898 receptor-mediated endocytosis 13/176 328/18862 0 4e-04 13
GO:2000377 regulation of reactive oxygen species metabolic process 10/176 192/18862 0 4e-04 10
GO:0097193 intrinsic apoptotic signaling pathway 12/176 283/18862 0 4e-04 12
GO:0043434 response to peptide hormone 15/176 435/18862 0 4e-04 15
GO:0010562 positive regulation of phosphorus metabolic process 24/176 982/18862 0 4e-04 24
GO:0045937 positive regulation of phosphate metabolic process 24/176 982/18862 0 4e-04 24
GO:0046916 cellular transition metal ion homeostasis 8/176 118/18862 0 4e-04 8
GO:0001819 positive regulation of cytokine production 15/176 437/18862 0 4e-04 15
GO:0022407 regulation of cell-cell adhesion 15/176 437/18862 0 4e-04 15
GO:0045851 pH reduction 6/176 58/18862 0 5e-04 6
GO:0003013 circulatory system process 18/176 610/18862 0 5e-04 18
GO:0070663 regulation of leukocyte proliferation 11/176 241/18862 0 5e-04 11
GO:0042554 superoxide anion generation 5/176 35/18862 0 5e-04 5
GO:0030162 regulation of proteolysis 20/176 733/18862 0 5e-04 20
GO:1901653 cellular response to peptide 14/176 391/18862 0 5e-04 14
GO:0048660 regulation of smooth muscle cell proliferation 9/176 160/18862 0 5e-04 9
GO:2001242 regulation of intrinsic apoptotic signaling pathway 9/176 160/18862 0 5e-04 9
GO:0002523 leukocyte migration involved in inflammatory response 4/176 18/18862 0 5e-04 4
GO:1990266 neutrophil migration 8/176 123/18862 0 5e-04 8
GO:0007596 blood coagulation 13/176 342/18862 0 5e-04 13
GO:0070997 neuron death 13/176 342/18862 0 5e-04 13
GO:0071621 granulocyte chemotaxis 8/176 124/18862 0 6e-04 8
GO:0048659 smooth muscle cell proliferation 9/176 162/18862 0 6e-04 9
GO:0050817 coagulation 13/176 347/18862 0 6e-04 13
GO:0002696 positive regulation of leukocyte activation 14/176 401/18862 0 6e-04 14
GO:0010744 positive regulation of macrophage derived foam cell differentiation 4/176 19/18862 0 6e-04 4
GO:1905477 positive regulation of protein localization to membrane 8/176 127/18862 0 6e-04 8
GO:0010742 macrophage derived foam cell differentiation 5/176 38/18862 0 6e-04 5
GO:0090077 foam cell differentiation 5/176 38/18862 0 6e-04 5
GO:0097242 amyloid-beta clearance 5/176 38/18862 0 6e-04 5
GO:1901214 regulation of neuron death 12/176 302/18862 0 7e-04 12
GO:0002701 negative regulation of production of molecular mediator of immune response 5/176 39/18862 0 7e-04 5
GO:0030212 hyaluronan metabolic process 5/176 39/18862 0 7e-04 5
GO:0032602 chemokine production 7/176 95/18862 0 7e-04 7
GO:0050870 positive regulation of T cell activation 10/176 212/18862 0 7e-04 10
GO:1901652 response to peptide 16/176 521/18862 0 7e-04 16
GO:0070265 necrotic cell death 6/176 65/18862 0 7e-04 6
GO:0030334 regulation of cell migration 23/176 962/18862 0 7e-04 23
GO:0048661 positive regulation of smooth muscle cell proliferation 7/176 96/18862 0 7e-04 7
GO:0016236 macroautophagy 12/176 311/18862 0 8e-04 12
GO:0034394 protein localization to cell surface 6/176 67/18862 0 9e-04 6
GO:0070661 leukocyte proliferation 12/176 312/18862 0 9e-04 12
GO:0010810 regulation of cell-substrate adhesion 10/176 218/18862 0 9e-04 10
GO:0097529 myeloid leukocyte migration 10/176 218/18862 0 9e-04 10
GO:0040007 growth 22/176 908/18862 0 9e-04 22