生物本体论分析工具箱。
基本信息
| 软件包 | 链接 |
|---|---|
| 编程语言 | R, C++ |
| Bioconductor | https://bioconductor.org/packages/simona/ |
| GitHub | https://github.com/jokergoo/simona |
| 文档 | https://jokergoo.github.io/simona/ |
| 论文 | Zuguang Gu, simona: a comprehensive R package for semantic similarity analysis on bio-ontologies. BMC genomics 2024. |
例子
library(simona)
dag = create_ontology_DAG_from_GO_db("BP", org_db = "org.Hs.eg.db")
dag
## An ontology_DAG object:
## Source: GO BP / GO.db package 3.17.0
## 27942 terms / 55956 relations
## Root: GO:0008150
## Terms: GO:0000001, GO:0000002, GO:0000003, GO:0000011, ...
## Max depth: 18
## Avg number of parents: 2.00
## Avg number of children: 1.88
## Aspect ratio: 363.92:1 (based on the longest distance from root)
## 782.78:1 (based on the shortest distance from root)
## Relations: is_a, part_of
## Annotations: 18614 items
## 291, 1890, 4205, 4358, ...
##
## With the following columns in the metadata data frame:
## id, name, definition