Toolbox for bio-ontology analysis.
Basic
| 软件包 | 链接 |
|---|---|
| Language | R, C++ |
| Bioconductor | https://bioconductor.org/packages/simona/ |
| GitHub | https://github.com/jokergoo/simona |
| Documentation | https://jokergoo.github.io/simona/ |
| Publication | Zuguang Gu, simona: a comprehensive R package for semantic similarity analysis on bio-ontologies. BMC genomics 2024. |
Example
library(simona)
dag = create_ontology_DAG_from_GO_db("BP", org_db = "org.Hs.eg.db")
dag
## An ontology_DAG object:
## Source: GO BP / GO.db package 3.20.0
## 26552 terms / 51745 relations
## Root: GO:0008150
## Terms: GO:0000001, GO:0000002, GO:0000011, GO:0000012, ...
## Max depth: 18
## Avg number of parents: 1.95
## Avg number of children: 1.83
## Aspect ratio: 343.15:1 (based on the longest distance from root)
## 756.89:1 (based on the shortest distance from root)
## Relations: is_a, part_of
## Annotations: 18986 items
## 291, 1890, 4205, 4358, ...
##
## With the following columns in the metadata data frame:
## id, name, definition