Sim_Lin_1998

Sim_Lin_1998(
  dag,
  terms,
  IC_method = "IC_annotation",
  verbose = simona_opt$verbose
)

Methods

The similarity between two terms a and b is calculated as the IC of their MICA term c normalized by the average of the IC of the two terms:

sim = IC(c)/((IC(a) + IC(b))/2) 
    = 2*IC(c)/(IC(a) + IC(b))

Although any IC method can be used here, in more applications, it is normally used together with the IC_annotation method.